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Search Results: 1 - 10 of 409425 matches for " Patrick M. Mukuna "
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Prognostic Signification of Admission Hyperglycemia among Acute Stroke Patients in Intensive Care Units in Kinshasa, the Democratic Republic of the Congo  [PDF]
Josée K. Tshituta, Fran?ois B. Lepira, Fran?ois P. Kajingulu, Jean Robert R. Makulo, Ernest K. Sumaili, Pierre Z. Akilimali, Aliocha N. Nkodila, Freddy M. Mbuyi, Angèle I. Masewu, Stéphane Mutombo, Eric B. Amisi, Jean Pierre M. Ilunga, Wilfrid B. Mbombo, Patrick M. Mukuna, Adolphe M. Kilembe
World Journal of Cardiovascular Diseases (WJCD) , 2019, DOI: 10.4236/wjcd.2019.99060
Abstract:
BACKGROUND AND AIM: Although admission hyperglycemia has been reported to be associated with unfavorable outcomes in acute stroke, little is known about this association in sub-Saharan Africa. Therefore, the aim of the present study was to assess the prognostic significance of admission hyperglycemia in the acute phase of stroke in Congolese patients. METHODS: In a multicenter prospective cohort study, consecutive patients with acute stroke were examined in 5 Emergency Rooms or Intensive Care Units of Kinshasa between July 15th, 2017 and March 15th, 2018. The severity of stroke was assessed at admission using the Glasgow Coma Scale. Stress hyperglycemia was defined as random blood glucose levels at admission > 140 mg/dL in patients without known type 2 diabetes mellitus (T2DM). The endpoint was 10-day all-cause in-hospital mortality. Survival (time-to-death) curves were built using the Kaplan Meier methods. Cox proportional analysis was used to identify predictors of 10-day all-cause in-hospital mortality. The predictive performance of blood glucose level
Defining Biomarker Performance and Clinical Validity
Patrick M. M. Bossuyt
Journal of Medical Biochemistry , 2011, DOI: 10.2478/v10011-011-0028-0
Abstract: In the evaluation of biomarkers three questions can be answered: what is the analytical validity of the marker, what is its clinical validity, and does the marker have clinical utility? In most cases, clinical validity will be expressed in terms of the marker's accuracy: the degree to which it can be used to correctly identify diseased patients or, more generally, patients with the target condition. Diagnostic accuracy is evaluated in studies in which the biomarker values are compared to the outcome of the clinical reference standard in the same patients. There are several ways in which the results of diagnostic accuracy studies can be summarized, reported, and interpreted. In this paper we summarize and present the available measures. We classify these as error-based measures, information-based measures, and measures of the strength of the association. Clinical validity is linked to clinical utility. If the target condition is well defined and associated with unequivocal downstream management decisions, clinical validity, when defined in comparative terms, may sometimes act as a surrogate outcome measure for clinical utility.
Photocatalytic Degradation of Paraquat Herbicide Using a Fixed Bed Reactor Containing TiO2 Nanoparticles Coated onto β-SiC Alveolar Foams  [PDF]
Ignace Christian M’Bra, Grah Patrick Atheba, Didier Robert, Patrick Drogui, Albert Trokourey
American Journal of Analytical Chemistry (AJAC) , 2019, DOI: 10.4236/ajac.2019.105015
Abstract: Photocatalytic degradation of paraquat (PQ) aqueous solutions was studied in a fixed bed photoreactor under UV irradiation at 368 nm. This contained β-SiC alveolar foams coated with TiO2 P25 by dip-coating method. SEM analyses revealed that the surface of the film did not exhibit cracks in the presence of TTIP as a binder in the TiO2 P25 suspension. The following parameters were studied in continuous mode operation: the flow rate in the reactor, the initial concentration of the paraquat, the pH of the solution, the weight of photocatalytic material with the number of foams in the reactor and the weight of the catalyst deposited onto the support. The results showed that by working under optimal operating conditions at natural pH (pH = 6.7), low paraquat (Co = 10 ppm), and flow (26 mL/min), we recorded approximately (43.16 ± 1.00)% oxidation of paraquat and a decrease in total organic carbon (TOC) of (27.13 ± 1.00)% after about 70 minutes. The apparent rate constant is in the order of (0.0656 ± 0.0010) min-1. In addition, by increasing the amount of β-SiC foams coated with TiO2, we improve the degradation of paraquat in the same order. The study of aging of the material showed its stability over time. However, photocatalytic activity was limited after 20 minutes of UV irradiation due to the limitation of the diffusion of the paraquat molecules towards the surface of the photocatalyst. As an outcome, we obtained an efficient TiO2/β-SiC material for photocatalytic degradation of organic compounds in water.
Child PIP: Making mortality meaningful by using a structured mortality review process to improve the quality of care that children receive in the South African health system
M Patrick, C Stephen
South African Journal of Child Health , 2008,
Abstract: The Child Healthcare Problem Identification Programme (Child PIP) uses the mortality review process to assess the quality of care that children receive in the South African health system, and to suggest solutions for improvement. This paper describes the origins, growth and development of Child PIP over the last 5 years, and provides an overview of the findings and recommendations to date. South African Journal of Child Health Vol. 2 (2) 2008: pp. 38-43
CALCITONIN/AMYLIN RECEPTORS AND RAMPS
Patrick M. Sexton
The Scientific World Journal , 2001, DOI: 10.1100/tsw.2001.442
Abstract:
The Death of Selective Waiver: How New Federal Rule of Evidence 502 Ends the Nationalization Debate
Patrick M. Emery
Journal of Law and Commerce , 2009, DOI: 10.5195/jlc.2009.12
Abstract: New Federal Rule of Evidence 502 (“FRE 502”) will end the threedecade push to nationalize a corporate litigation protection known as the “selective waiver doctrine.” First adopted by the Eighth Circuit in 1978, the selective waiver doctrine holds that, when a corporation discloses privileged materials to a government agency during an investigation, the corporation retains its privileges against third-party litigants—i.e., the corporation may selectively waive its attorney-client privilege (and in other circuits its attorney work product protection). This flies in the face of traditional waiver rules, under which a waiver of privilege to one’s adversary generally is a waiver to all adversaries on that subject matter. Based on years of frustration with discovery costs, fear of corporate fraud, and heavy burdens placed on administrative agencies, many legal scholars praised selective waiver as a cure for those ills. Recently, when the Advisory Committee on Evidence Rules met to discuss additions to the FRE, many called for the inclusion of a selective waiver provision. After much debate, the Advisory Committee determined that the selective waiver proposal for FRE 502 was too controversial. In its enacted form, FRE 502 does not contain a selective waiver provision.
Arf invariants of real algebraic curves
Patrick M. Gilmer
Mathematics , 2005, DOI: 10.2140/pjm.2007.230.297
Abstract: We give some new congruences for singular real algebraic curves which generalize Fiedler's congruence for nonsingular curves.
Remarks on Congruence of 3-manifolds
Patrick M. Gilmer
Mathematics , 2007, DOI: 10.1142/S021821650700583X
Abstract: We give two proofs that the 3-torus is not weakly d-congruent to the connected sum of three S^1xS^2's, if d>2. We study how cohomology ring structure relates to weak congruence. We give an example of three 3--manifolds which are weakly 5-congruent but are not 5-congruent.
Quantum invariants of periodic three-manifolds
Patrick M. Gilmer
Mathematics , 1999,
Abstract: Let p be an odd prime and r be relatively prime to p. Let G be a finite p-group. Suppose an oriented 3-manifold M-tilde has a free G-action with orbit space M. We consider certain Witten-Reshetikhin-Turaev SU(2) invariants w_r(M). We will give a fomula for w_r(M) in terms of the defect of M-tilde --> M and the number of elements in G. We also give a version of this result if M and M-tilde contain framed links or colored fat graphs. We give similar formulas for non-free actions which hold for a specified finite set of values for r.
Heegaard genus, cut number, weak p-congruence, and quantum invariants
Patrick M. Gilmer
Mathematics , 2008, DOI: 10.1142/S021821650900749X
Abstract: We use quantum invariants to define a 3-manifold invariant j_p which lies in the non-negative integers. We relate j_p to the Heegard genus, and the cut number. We show that j_$ is an invariant of weak p-congruence.
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