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Search Results: 1 - 10 of 203592 matches for " Patel P "
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Enterprise Service Bus: A Performance Evaluation  [PDF]
Sanjay P. Ahuja, Amit Patel
Communications and Network (CN) , 2011, DOI: 10.4236/cn.2011.33016
Abstract: The flexibility offered by an Enterprise Service Bus (ESB) in enabling various applications to exchange data makes it a very important middleware layer that is responsible for transporting data in a Service-Oriented Architecture (SOA). The popularity of the ESB has given rise to a number of commercial off the shelf (COTS) products as well as open source ESBs. In this study, we evaluated three open source ESBs and compared them both qualitatively and quantitatively. The empirical results were statistically tested to determine the statistical significance of the results.
Polymer in Sustainable Energy  [PDF]
Darshan Patel, S. P. Deshmukh
Journal of Minerals and Materials Characterization and Engineering (JMMCE) , 2012, DOI: 10.4236/jmmce.2012.117049
Abstract: A transparent polymer based solar cell was designed and fabricated to utilize the solar energy when exposed to sunlight. The transparent solar cell for window module was composed of a polymeric material PPV (Polyphenylene vinylene), ITO (Indium Tin Oxide) and electrode (Al, Mg, Ca). The polymeric sheet of this cell is by casting process, and electrode is applied on it by CVD (Chemical Vapor Deposition) process. The solar energy collected by this window can be used to power up small household electrical appliances. Recently, polymeric solar cell is made by a roll-to-roll process without using indium-tin oxide (ITO). A commercially available kapton (Polyimide) foil with an over layer of copper was used as the substrate. Sputtering of titanium metal on to the kapton/copper in a vacuum metalizing process gave the monolithic substrate and back electrode for the devices. The active layer was slot-die coated on to the kapton/Cu/Ti foil followed by slot-die coating of a layer of PET, PC or PEN.
Characterization & Simulation Of Class AB Current Conveyor Second Generation (CCII) Based On Current Mirrors
Dhaval P. Patel,Mitesh Patel
Golden Research Thoughts , 2013, DOI: 10.9780/22315063
Abstract: Research in analog integrated circuits has recently gone in the direction of low voltage (LV) lowpower (LP) design especially in the environment of portable systems. In this area traditional voltage-mode techniques are going to be substituted by the current-mode approach which has the advantage to overcome the gain-bandwidth product limitation typical of operational amplifier. Then they do not require high voltage gains and have good performance in terms of speed bandwidth and accuracy. Inside the current-mode architectures the current-conveyor (CCII) can be considered the basic circuit block because all the active devices can be made of a suitable connection of one or two CCIIs. Recent advances in integrated circuit technology have also highlighted the usefulness of CCII solutions in a large number of signal processing applications. This project describes different topologies of CCIIs. All topologies have been simulated in different CMOS process technologies using Eldo Spice tool and layout is made using Mentor Graphics Back End tools like IC Station and DA-IC. Different characteristics such as gain, bandwidth, terminal impedances, slew rate, dynamic range, input-output current characteristic and offset are measured and tabulated for all theCCII topologies.
Parallel Manipulators Applications—A Survey  [PDF]
Y. D. Patel, P. M. George
Modern Mechanical Engineering (MME) , 2012, DOI: 10.4236/mme.2012.23008
Abstract: This paper presents the comparison between serial and parallel manipulators. Day by day, the applications of the parallel manipulator in various field is become apparent and with a rapid rate utilized in precise manufacturing, medical science and in space exploration equipments. A parallel manipulator can be defined as a closed loop kinematic chain mechanism whose end effector is linked to the base by several independent kinematic chains. The classification of various parallel manipulators is presented herewith. The prime focus of the paper is to realize the parallel manipulators applications for industry, space, medical science or commercial usage by orienting manipulator in the space at the high speed with a desired accuracy.
Mechanisms of potentiation of Angiotensin II-induced contractile response of isolated rat aorta by hydrogen peroxide and tert-butyryl hydroperoxide
Patel R,Patel P,Patel M,Patel N
Indian Journal of Pharmacology , 2009,
Abstract: Objective: To study the mechanism involved in hydrogen peroxide (H 2 O 2 ) or tert-butyl hydroperoxide (t-BHP)-induced potentiation of the Ang II-mediated contraction of isolated rat thoracic aorta. Materials and Methods: Thoracic aorta was isolated from the Sprauge dawley rats (300-320 gm), cut spirally and response to Ang II (5 ′ 10 -8 M) was taken in the absence and presence of H 2 O 2 (10 -6 M) and t-BHP (10 -5 M). To explore the probable mechanism of H 2 O 2 and t-BHP-induced potentiation of Ang II-mediated contractile response, different blockers such as losartan (AT 1 receptor blocker; 1 μM), catalase (H 2 O 2 scavenger; 500 U/ml), lercanidipine (L-type calcium channel blocker; 1 μM), geinistein (tyrosine kinase inhibitor; 100 μM), and indomethacin (cyclo-oxygenase inhibitor; 10 μM) were used. Results: In spiral preparation of rat thoracic aorta, H 2 O 2 (10 -6 M) and t-BHP (10 -5 M) did not produce the contraction as such. However, when they are added simultaneously with Ang II (5 ′ 10 -8 M), they potentiated the contractile response of the Ang II. Catalase (500 U/ml) partially antagonized the Ang-II-induced contraction, as well as antagonized the potentiation induced by H 2 O 2 . Losartan (1 μM) and lercanidipine (1 μM) antagonized the Ang II-induced contractile response without affecting H 2 O 2 (10 -6 M)-mediated potentiation. Geinistein (100 μM) antagonized H 2 O 2 (10 -6 M)-mediated potentiation, but it slightly decreased the Ang II response. Losartan (1 μM) and lercanidipine (1 μM) and Geinistein (100 μM) antagonized the Ang II-induced contractile response but not t-BHP-mediated potentiation. Indomethacin antagonized t-BHP-mediated potentiation without affecting much of Ang II response. Conclusion: From the above-mentioned results, we can reasonably conclude that H 2 O 2 and t-BHP potentiated the contraction induced by the Ang II. H 2 O 2 -induced potentiation of Ang II response may be mediated through tyrosine kinase activation and t-BHP through the activation of cyclo-oxygenase enzyme.
High performance thin layer chromatographic method for estimation of linezolid in tablets
Patel S,Patel P,Patel N,Patel M
Indian Journal of Pharmaceutical Sciences , 2007,
Abstract: A simple and sensitive high performance thin layer chromatography (HPTLC) method has been developed for the quantitative estimation of linezolid in its single component tablet formulations (600 mg). Linezolid was chromatographed on Silica Gel 60 F254 TLC plate using methanol: benzene (2:8 v/v) as mobile phase. Linezolid showed Rf value 0.45 + 0.03 and scanned at 258 nm using a Camag TLC scanner 3. The method was validated in terms of linearity (200-1400 ng/spot), precision (intra-day variation, 0.75 to 1.26% and inter-day variation, 1.2 to 2.8%), accuracy (97.8 to 100.4%) and specificity. The limit of detection and limit of quantification for linezolid were found to be 16.7 ng/spot and 50.7 ng/spot, respectively. The developed method was successfully used for the assay of linezolid tablet formulations. The method was found to be simple, sensitive, specific, accurate and precise and can be used for the routine quality control testing of linezolid marketed formulations.
Estimation of duloxetine hydrochloride in pharmaceutical formulations by RP-HPLC method
Patel Sejal,Patel N,Patel K,Patel P
Indian Journal of Pharmaceutical Sciences , 2008,
Abstract: Simple, specific, accurate and precise method, namely, reverse phase high performance liquid chromatography was developed for estimation of duloxetine HCl in pharmaceutical formulations. For the high performance liquid chromatography method, Phenomenox C-18, 5 μm column consisting of 250x4.6 mm i.d. in isocratic mode, with mobile phase containing 0.01M 5.5 pH phosphate buffer: acetonitrile (60:40 v/v) and final pH adjust to 5.5±0.02 with phosphoric acid was used. The flow rate was 1.2 ml/min and effluent was monitored at 231 nm. The retention time was 5.61 min. The method was validated in terms of linearity, accuracy and precision. The linearity curve was found to be linear over 0.25-4 μg/ml. The limit of detection and limit of quantification were found to be 0.10 and 0.25 μg/ml respectively. The proposed method was successfully used to determine the drug content of marketed formulations.
CARDIOTONIC ACTIVITY OF ISOLATED CARDIAC GLYCOSIDE FROM THE FRUITS OF CORCHORUS AESTUANS LINN
Patel Rashmika P.,Patel Manish P.
International Research Journal of Pharmacy , 2012,
Abstract: Preliminary phytochemical investigation of various extracts of fruits of Corchorus aestuans Linn showed the presence of cardiac glycosides, triterpenes, carbohydrates, saponins, flavonoids, tannins and fatty acids. An attempt has been made to isolate cardiac glycoside and perform cardiotonic activity of the same. The cardiotonic effect was studied by using isolated frog heart perfusion technique (IFHP). Ringer solution without calcium was used as a vehicle for administration of isolated cardiac glycoside as test and digoxin as standard. A significant increase in the height of force of contraction (positive inotropic effect) and decrease in heart rate (negative chronotropic effect) was observed at smaller doses (0.4 mg). The effect increased as dose was increased. The test compound had not produced cardiac arrest even at a dose of 2 mg, a higher concentration as compared to standard, digoxin that showed cardiac arrest at dose of 0.2 mg. Hence, as compared to standard, test drug showed wide therapeutic index.
EVALUATION OF ANTIOXIDANT ACTIVITY OF CORCHORUS AESTUANS LINN LEAVES EXTRACTS
Patel Rashmika P.,Patel Manish P.
International Research Journal of Pharmacy , 2012,
Abstract: The leaves of Corchorus aestuans Linn are said to cure gonorrhea and used in making an injection for urethral discharge. In the present study, the antioxidant potency of Corchorus aestuans Linn crude methanol and its fractionated extracts (hexane, ethyl acetate and water) have been investigated, employing three different established in vitro testing systems, such as scavenging activity on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals, reducing power assay and β-carotene method. The data obtained in these testing systems clearly establish the antioxidant potency of Corchorus aestuans Linn. As such, this is the first report on the antioxidant activities of Corchorus aestuans Linn.
An Unusual Case of Obscure Gastrointestinal Bleeding in a Patient with Coeliac Disease
M. Gwiggner,P. Patel
Case Reports in Gastrointestinal Medicine , 2011, DOI: 10.1155/2011/634684
Abstract: This paper describes the journey of a patient with coeliac disease who presented with overt obscure gastrointestinal bleeding. Upper and lower gastrointestinal endoscopy did not reveal a source of bleeding, but an abdominal CT scan detected abnormal lymphadenopathy and a wireless capsule endoscopy diagnosed a jejunal tumour, which was surgically removed. Gastrointestinal bleeding is rare in celiac disease. Malignant tumours of the small intestine are generally uncommon, but celiac disease represents a significant risk factor. Wireless capsule endoscopy has been a useful tool to investigate patients with obscure gastrointestinal bleeding.
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