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Search Results: 1 - 10 of 110 matches for " Paraganglioma "
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Cardiac Paraganglioma—A Rare Subset of a Rare Tumor  [PDF]
Alecsandra-Anca Tudor, Jo?lle Tschui, Jürg Schmidli, Ralph A. Schmid, Patrick Dorn
World Journal of Cardiovascular Diseases (WJCD) , 2017, DOI: 10.4236/wjcd.2017.71001
Background: Cardiac paraganglioma is a rare entity of an uncommon neuroendocrine tumor. Clinically, non-secreting tumors are often diagnosed because of their growth effects, secreting tumors present symptoms related to catecholamine. Correct diagnosis of a paraganglioma can be reached by biochemical investigations and imaging. Surgical resection is the treatment of choice and has to be planned carefully and interdisciplinarily. Aim: On the basis of a patient with a vague clinical presentation and an unclear situation after primary investigations, we highlight the diagnostic challenge of this rare subset of paragangliomas. Case presentation: We present the case of a 42-year-old woman whose unspecific symptoms and further investigations revealed a paracardiac mass with unknown local behavior and dignity. Surgical resection and histopathological examination led to the diagnosis of a cardiac paraganglioma. Conclusion: Cardiac paragangliomas are extremely rare, but may be treated curatively by resection after careful preoperative investigation and interdisciplinary planning.
Undiagnosed Abdominal Paraganglioma: An Anaesthetic Challenge  [PDF]
Lalit Gupta, Sanjay Kr. Nihalani, Saipriya Tiwari, Poonam Bhadoria, Sonia Wadhawan
Open Journal of Anesthesiology (OJAnes) , 2013, DOI: 10.4236/ojanes.2013.310091

Paragangliomas are tumours which arise in extra adrenal autonomic paraganglia and have the ability to secrete catecholamines. Their anaesthetic management is the same as that of a case of pheochromocytoma, but in an undiagnosed case like our patient, unexpected eventful encounter in the operating theatre may lead to life threatening complications during surgical resection warranting immediate management and thus posing a real challenge to the skill of an anaesthesiologist.

Tríada de Carney incompleta e hipertensión arterial en una mujer joven Incomplete Carney’s triad and arterial hypertension in a young woman
Alberto Allievi,Valentina Araya,Cecilia Calvar,Conrado Cimino
Medicina (Buenos Aires) , 2006,
Abstract: Se presenta una el caso de paciente joven, con tríada de Carney incompleta que cursa hipertensión arterial de dos a os de evolución y anemia ferropénica grave por pérdida crónica de sangre por tubo digestivo, con tumores gástricos múltiples y paraganglioma pararrenal. No presenta aún desarrollo de condromas pulmonares visibles por tomografía axial computada. En nuestra paciente el paraganglioma no resultó funcionante. Resaltamos que la presencia de tumores gástricos múltiples en un adulto joven debe sugerir la posibilidad de tumores estromales (GIST), cuyo diagnóstico por biopsia endoscópica es difícil debido a su localización profunda, situada en las capas musculares de la pared gástrica. Asimismo queremos remarcar la importancia de las técnicas de marcación descriptas para el diagnóstico preciso. El seguimiento debe ser constante dado el pronóstico incierto de estos tumores. Los condromas pulmonares pueden aparecer a os después de la resección del GIST y ser confundidos con metástasis del GIST. The case of young woman with arterial hypertension diagnosed two years before, is here presented; she had a ferropenic anemia caused by digestive loss of blood. Multiple gastric tumors and pararenal non functioning paraganglioma were found. No chondromas were detected. An incomplete Carney’s Triad was diagnosed. We remark that multiple gastric tumors in a young adult suggest the possibility of gastrointestinal stromal tumors (GIST) Endoscopic biopsy frequently is not effective because these tumors are deep placed in the muscular gastric layers. The importance of specific techniques for a positive diagnosis are emphasized. Continuous follow up is needed because these tumors have uncertain prognosis. Lung chondromas may appear years later after the GIST was removed and might be confused with GIST metastases.
Synchronous malignant vagal paraganglioma with contralateral carotid body paraganglioma treated by radiation therapy
Tejinder Kataria,Shyam Singh Bisht,Swarupa Mitra,Ashu Abhishek
Rare Tumors , 2010, DOI: 10.4081/rt.2010.e21
Abstract: Paragangliomas are rare tumors and very few cases of malignant vagal paraganglioma with synchronous carotid body paraganglioma have been reported. We report a case of a 20-year old male who presented with slow growing bilateral neck masses of eight years duration. He had symptoms of dysphagia to solids, occasional mouth breathing and hoarseness of voice. Fine needle aspiration cytology (FNAC) performed where he lived showed a sinus histiocytosis and he was administered anti-tubercular treatment for six months without any improvement in his symptoms. His physical examination revealed pulsatile, soft to firm, non-tender swellings over the anterolateral neck confined to the upper-mid jugulo-diagastric region on both sides. Direct laryngoscopy examination revealed a bulge on the posterior pharyngeal wall and another over the right lateral pharyngeal wall. Magnetic resonance imaging (MRI), 99mTc-labeled octreotide scan and angiography diagnosed the swellings as carotid body paraganglioma, stage III on the right side with left-sided vagal malignant paraganglioma. Surgery was ruled out as a high morbidity with additional risk to life was expected due to the highly vascular nature of the tumor. The patient was treated with radiation therapy by image guided radiation to a dose of 5040cGy in 28 fractions. At a follow-up at 16 months, the tumors have regressed bilaterally and the patient can take solids with ease.
Paraganglioma pré-aórtico gigante
Costa, Sergio Renato Pais;Pinheiro, Rodrigo Nascimento;Piazzola, Luciana Paganini;Takano, Gustavo Henrique Soares;Lupinacci, Renato Arioni;
ABCD. Arquivos Brasileiros de Cirurgia Digestiva (S?o Paulo) , 2008, DOI: 10.1590/S0102-67202008000400012
Abstract: racional: paraganglioma is a rare neuroendocrine tumor which often diagnosed in the young adult. generally, paraganglioma produces catecholamines causing adrenergic syndrome. however, more rarely when tumor is nonfunctioning, their symptoms are more associated with an abdominal mass or even pain. in these circumstances, paraganglioma present a difficult diagnosis confounding with retroperitoneal sarcomas. case report: the authors present a case of nonfunctioning giant preaortic paraganglioma. this patient had low levels of catecholamines (both seric and urinary). the preoperative diagnosis was done by means computed tomography. this lesion presented as well-vascularized tumor with calcifications and necrotic central area. the patient underwent a surgical resection with good postoperative outcome. to date, one year after surgical treatment, the patient is alive without recurrence. conclusion: despite its rarity, non-funcionating preaortic paraganglioma should be reminded with differential diagnosis with retroperitoneal sarcomas. treatment is surgical resection and presents a good prognosis.
Paraganglioma del nervio vago
Torres-Carranza,E.; Infante-Cossío,P.; García-Perla,A.; Belmonte,R.; Menéndez,J.; Gutiérrez-Pérez,J.L.;
Neurocirugía , 2006, DOI: 10.4321/S1130-14732006000300006
Abstract: paragangliomas of the vagus nerve are uncommon vascular benign neoplasms of neuroectodermic origin. initial clinical manifestation is usually as an asymptomatic cervical mass, although sometimes may cause lower cranial nerve palsies. these paragangliomas seldom associate to high levels of circulating catecholamines. diagnosis is based on the clinics aided by imaging, where ct and mri play an important role. angiography is not only diagnostic, but it also allows preoperative embolization of the mass. most accepted treatment is surgical removal, even though some paragangliomas are suitable for radiation therapy in very specific patients. in this paper we describe a new case of paraganglioma of the vagus nerve in a cervical location, with hypertensive episodes and high catecholamine-levels. the authors review the literature describing the clinical presentation, the diagnosis and the treatment of this rare lesion.
Tríada de Carney incompleta e hipertensión arterial en una mujer joven
Allievi,Alberto; Araya,Valentina; Calvar,Cecilia; Cimino,Conrado; Delle Piane,Hugo; Díaz,Gabriela; Gianni,Marta; Prudkin,Ludmila;
Medicina (Buenos Aires) , 2006,
Abstract: the case of young woman with arterial hypertension diagnosed two years before, is here presented; she had a ferropenic anemia caused by digestive loss of blood. multiple gastric tumors and pararenal non functioning paraganglioma were found. no chondromas were detected. an incomplete carney?s triad was diagnosed. we remark that multiple gastric tumors in a young adult suggest the possibility of gastrointestinal stromal tumors (gist) endoscopic biopsy frequently is not effective because these tumors are deep placed in the muscular gastric layers. the importance of specific techniques for a positive diagnosis are emphasized. continuous follow up is needed because these tumors have uncertain prognosis. lung chondromas may appear years later after the gist was removed and might be confused with gist metastases.
Paraganglioma carotídeo bilateral
Galv?o Jr., Ant?nio R.;Sartini, André L.;Machado, Márcia C.;Mattioli, Fernando M.;Ribas, Marcelo H.;Fava, Ant?nio S.;
Revista Brasileira de Otorrinolaringologia , 2004, DOI: 10.1590/S0034-72992004000400023
Abstract: carotid body paragangliomas are uncommon lesions although in the head and neck region, these lesions are the most frequent ones. bilateral lesions are rare. the authors present a case of bilateral paraganglioma, its clinical aspects, diagnosis and treatment.
Tumor de cuerpo carotídeo
Revista chilena de cirugía , 2011, DOI: 10.4067/S0718-40262011000500013
Abstract: carotid body tumors (paragangliomas) are very rare, highly vascularized and usually benign tumors, originated in the carotid body chemoreceptors. we present the cases of two asymptomatic patients referred for left cervical mass; preoperative study was ct and ct angiography, respectively, which are consistent with carotid body tumors. the tumors were completely removed by subadventitial disection without complications; the biopsy was compatible with paraganglioma. no evidence of recurrence could be found.
Emboliza??o pré operatória no tratamento de paraganglioma abdominal: relato de caso
Nakamura, Fernando;Silva, Rodrigo Altenfelder;Santos, Vanessa Prado dos;Razuk Filho, álvaro;Caffaro, Roberto Augusto;
Revista do Colégio Brasileiro de Cirurgi?es , 2010, DOI: 10.1590/S0100-69912010000200015
Abstract: paragangliomas is a pheochromocytoma of extra adrenal localization. the case report is a male, 55 years old who presented symptoms of adrenergic hyperstimulation associated to an abdominal mass diagnosed as paraganglioma by a biopsy. because of its size, localization and vascularization, an aortography with embolization of the nutrient branches of the tumor was done pre-operatively. four days later, a surgical ressection was performed, and the tumor was adhered to the duodenum, infra-renal aorta and inferior vena cava. we believe that an angiographic study pre-operatively with embolization makes possible an analysis of the anastomosis and arterial supplement, making the ressecability of the tumor safer, although it seems the surgical intervention should have been done earlier.
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