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Search Results: 1 - 10 of 704 matches for " Pancreas "
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Pancreas Transplant Salvage by Proximal Loop Ileostomy and Distal Ileostotomy Tube for Duodenal Stump Leak after Enteric Conversion  [PDF]
Monroy-Cuadros Mauricio, Rodriguez-Velez Cesar
Surgical Science (SS) , 2011, DOI: 10.4236/ss.2011.21001
Abstract: After pancreas transplantation, some patients with bladder drainage (BD) of the pancreatic duct will need to be converted to enteric drainage (ED) because of reflux pancreatitis, metabolic acidosis, and urological complications. However, ED is associated with higher rates of duodenal stump leak, intra-abdominal abscess, and peritonitis. In some cases of enteric anastomosis leakage, a primary repair can be attempted, but in more severe cases, graft pancreatectomy is indicated. We report one patient who received a combined kidney and pancreas transplant with BD of exocrine secretions, but who required ED conversion 6 years later because of persistent metabolic acidosis and adverse urological symptoms. However, a significant duodenal leak was discovered 4 days post-operatively. To salvage the transplanted pancreas, we performed a diverting loop ileostomy proximal to the entero-entero anastomosis and the distal section was drained retrogradely with an ileostostomy tube, allowing the area of the leak to heal. Three months later, the ileostomy was reversed without complications, the symptoms that led to the ED conversion resolved, and the kidney and pancreas allografts remain functional 48 months later. We suggest that this might be a method by which transplanted pancreas may be salvaged in the case of leakage after ED conversion.
Oncomodulin and macrophages derived factors in pancreas injury and development paradigms  [PDF]
Jo?l Fleury Djoba Siawaya, Carmen Capito, Raphael Scharfmann
Modern Research in Inflammation (MRI) , 2013, DOI: 10.4236/mri.2013.21001
Abstract: Prior studies in the optic nerve injury paradigm showed con?icting data regarding production and signi?cance of the Ca2+-binding protein oncomodulin (OCM). Some have shown its potentaxon-regenerative or-growth attribute, where other showed little to no effect. We show here that pancreas inflammation lead to macrophages infiltration that produce OCM and inflamed tissues that express OCM receptorsin vivo. In culture OCM has a cytostatic effect on embryonic pancreas explants. Secretory products of zymosan activated macrophages are cytotoxic and factors derived from non-activated macrophages seem to promote pancreas development. It is our view that OCM is involved in protective injury response that allows through metabolism slowing sublethally injured cells to undergo recovery.
Squamous Cell Carcinoma of the Pancreas  [PDF]
Pierlesky Elion Ossibi, Issam Yazough, Amal Bennani, KarimIbn Majdoub, Imane Toughrai, Said Ait Laalim, Abdelmalek Ousadden, Laila Chbani, Khalid Mazaz, Khalid Ait Taleb
Surgical Science (SS) , 2014, DOI: 10.4236/ss.2014.510075
Abstract: Exocrine pancreatic tumors are dominated by adenocarcinomas that have a poor prognosis. Squamous Cell Carcinoma of the pancreas is rare. We report a case of squamous cell carcinoma of the pancreas in a 75-year-old patient admitted to the emergency ward with acute cholangitis.
Solid-Pseudopapillary Tumor of the Pancreas in Adults: A Case Report  [PDF]
Kamil Gulpinar, Suleyman Ozdemir, Erpulat Ozis, Sadik Ersoz
Surgical Science (SS) , 2013, DOI: 10.4236/ss.2013.41014
Abstract: Solid-pseudopapillary tumor of the pancreas (SPTP) is an uncommon low grade exocrine pancreatic malignancy. We represented a 22 years old female with an abdominal mass of 4 years history and symptoms of weakness, loss of appetite, 7 kilograms weight loss and swelling for almost 2 months. She was suspected of pancreatic malignancy due her abdominal ultrasound and CT reports and therefore underwent explorative surgery that revealed a huge pancreatic tumor .The tumor was resected totally and hystopathological examination reported significant components of pancreatic solid pseudopapiller tumor features which was also the final diagnosis.

Annular pancreas producing duodenal obstruction: A case report  [PDF]
Abdesslam Bouassria, Hicham Elbouhaddouti, Ouadii Mouaqit, El Bachir Benjelloun, Abdelmalek Ousadden, Khalid Mazaz, Khalid Ait Taleb
Open Journal of Gastroenterology (OJGas) , 2013, DOI: 10.4236/ojgas.2013.33032

Annular pancreas is a rare congenital anomaly characterized by the presence of ectopic pancreatic tissue surrounding the duodenum. This malformation is usually asymptomatic in adults, but can manifests as pancreatitis, duodenal stenosis, or duodenal or gastric ulceration. We report the case of a young patient of 18 years old hospitalized for epigastric pain and vomiting, in whom radiological investigations showed an annular pancreas. At operation, a complete obstruction of the duodenum between its first and second parts was found, caused by an annular pancreas. No other congenital anomaly of the intra abdominal organs was noted. A gastroenterostomy was performed. Both the rarity of this congenital abnormality and its successful correction by surgical means have prompted us to make the following presentation.

The Expression of Surfactant Proteins A and D in the Intestines and Pancreas of Murine Fetuses  [PDF]
Ryuta Saka, Hiroomi Okuyama, Kaoru Uchida, Kumiko Nakahira, Takashi Sasaki, Satoko Nose, Masahiro Nakayama, Masahiro Fukuzawa, Itaru Yanagihara
Open Journal of Pediatrics (OJPed) , 2014, DOI: 10.4236/ojped.2014.41002

Purpose: Surfactant proteins exist in the digestive tract and may play an important role in the host defense. However, the expression of surfactant proteins in the premature digestive system remains unclear. The aim of this study was to investigate the expression of surfactant proteins in the intes-tines and pancreas of murine fetuses. Methods: Immunostaining for SP-A and SP-D was assessed in the small intestine and pancreas of ICR murine fetuses on days 15, 16, 17 and 18 of gestation (normal duration of pregnancy: 19 - 21 days). RT-PCR was performed to detect the expression of spa and spd mRNA in the small intestine and pancreas on day 16, 17 and 18 of gestation. Results: Immunoreactivity for SP-A and SP-D in the

Neoadjuvant Therapy for Resectable and Borderline Resectable Pancreatic Cancer  [PDF]
Susan Tsai, Kathleen K. Christians, Ben George, Paul Ritch, Kiyoko Oshima, Parag Tolat, Ashley Krepline, Beth A. Erickson, Douglas B. Evans
Journal of Cancer Therapy (JCT) , 2016, DOI: 10.4236/jct.2016.71004
Abstract: The majority of patients with localized pancreatic cancer (PC) who undergo surgery followed by adjuvant therapy will develop metastatic disease, suggesting that surgery alone is not sufficient for cure and micrometastases are present even when are not clinically detected. As such, the delivery of early systemic therapy may be a rational alternative to a surgery-first approach, in an effort to provide oncologic therapies which are commensurate with the disease stage, and improve surgical selection. This review details the rationale for a neoadjuvant approach to localized PC and provides specific recommendations for both pretreatment staging and treatment sequencing for patients with resectable and borderline resectable PC.
A primary pancreatic carcinoid tumour with unusual clinical complaints: A case report
Olivier Saint-Marc, Andrea Cogliandolo, Alessandro Pozzo, Rocco Pidoto
World Journal of Surgical Oncology , 2004, DOI: 10.1186/1477-7819-2-3
Abstract: The reported case of pancreatic carcinoid tumour in a 62-year-old woman reporting only atypical symptoms consisting of intermittent epigastric pain and nausea. Urinary 5-hydroxyindolacetic acid levels were within normal limits and only a slight elevation of serum serotonine level was detected on admission. After tumour localisation with endoscopic ultrasonography, left splenopancreasectomy with splenic, celiac and hepatic lymphadenectomy was carried out.The role of endoscopic ultrasonography in early detection and precise localisation of pancreatic carcinoids, as well as the role of somatostatin-receptor scintigraphy with 111Indium labelled pentreotide in excluding distant metastases, are confirmed. The radical resection with lymphadenectomy is recommended in order to have a precise histological examination and detect occult lymph node metastases.Although carcinoid tumours are the most frequently occurring neuroendocrine tumours, its pancreatic localisation is an exceedingly rare, and often accidental [1]. In the largest published series of 8,305 cases of carcinoid tumours by Modlin and Sandor [2] only 46 (0.55%) were in the pancreas.Unless metastatic or compressing the pancreatic duct, carcinoid tumours of the pancreas are asymptomatic, with normal levels of serotonine and its metabolites in plasma and urine [3]. Though the exact ratio of functioning versus nonfunctioning carcinoid tumours is not yet known, for pancreatic tumours it was estimated to be 1:10 [4]. In contrast, there are pancreatic carcinomas with neuroendocrine characteristics and carcinoid-like-symptoms [5]. For these reasons, a late diagnosis and a consequent poor prognosis are usual patterns for pancreatic carcinoid. In the Modlin and Sandor series [2], at the time of diagnosis, 76% of pancreatic carcinoid were non-localised, and the 5-year survival rate was only 34.1%.In the recent revised classification of neuroendocrine tumours [6] the size of 2 cm seems to be of a crucial value over which carc
A ultra-sonografia do pancreas é eficaz em diagnosticar o diabete melito tipo 1 e tipo 2?
Pimenta, Walkyria de Paula;Teixeira, Altamir Santos;Aragon, Flávio Ferrari;Baptistelli, Elda Eveline;Moreira, Adriana Guanaes;Castro, Ana Valéria Barros de;Padovani, Carlos Roberto;
Radiologia Brasileira , 2002, DOI: 10.1590/S0100-39842002000400006
Abstract: the aim of this study was to determine whether ultrasonography of the pancreas can be used as an auxiliary tool in the diagnosis of adult patients with type 1 and type 2 diabetes mellitus. the size and echogenicity of the pancreas were evaluated by ultrasound in 81 diabetic patients: 20 type 1 and 61 type 2 (53 obese and 8 non-obese). obese type 2 diabetic patients showed different results from patients in the other groups, with significantly larger pancreas area and anteroposterior body diameter. the pancreas was more frequently hyperechogenic in obese type 2 diabetic patients than in type 1 diabetic patients. we concluded that ultrasonography of the pancreas may be used as an auxiliary tool for the diagnosis of type 1 and type 2 diabetic patients, although this method showed to be less efficient in non-obese patients.
Lipoma da cabe?a do pancreas
Garcia, José Huygens Parente;Sampaio, Leonardo Mesquita;Vasconcelos, Denissa Ferreira Gomes;
Revista do Colégio Brasileiro de Cirurgi?es , 2001, DOI: 10.1590/S0100-69912001000600015
Abstract: intrapancreatic lipoma is an extremely rare neoplasm. the authors present a case of pancreatic lipoma in a 51-years-old white female, with a history of abdominal pain for a twelve-month period, without other findings. computed tomography scanning showed a 5cm tumor located at the head of the pancreas. after surgical excision of a solid mass, histological study reveled a benign neoplasm of fat-cells, surrounded for normal pancreatic tissue. the authors comment on the more important aspects of this pathology.
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