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Search Results: 1 - 10 of 8653 matches for " PM;Moreno "
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Intradermal injection of Bothrops cotiara venom in mice in an experimental wound model
Lopes, JA;Giménez, APL;Zischler, LFCM;Stuelp-Campelo, PM;Moreno, AN;Elifio-Esposito, SL;
Journal of Venomous Animals and Toxins including Tropical Diseases , 2012, DOI: 10.1590/S1678-91992012000100009
Abstract: bothropic envenomation induces hemorrhage, coagulant disturbances and necrosis. regarding therapies against the local damage caused by the venom, there is little information on tissue changes until the complete healing. in the current study, local damage was evaluated by examination of morphological inflammatory alterations, mast cell count, and analysis of collagen deposition. bleeding was evident four hours after inoculation. after 24 hours, a large area of injury appeared presenting disorganized tissue, significant hemorrhage and acute inflammation. after three days, the damaged area was extensive, with a large amount of inflammatory cells and the presence of scab. in seven days, healing and reepithelization process started. and, 21 days later, the epithelium showed less infiltration and no skin appendages. the number of mast cells was similar to control after four hours, with a drop of 50% at 24 hours, followed by an increase until the 21st day. no differences of collagen deposition were observed among experimental groups. taken together, wound healing after intradermal injection of bothrops cotiara venom in mice follows similar parameters to wounds caused by other bothropic venoms. the present work reveals the importance of experimental wound models to the study of neutralizing agents against venom toxins.
Bias in multiple genetic correlation from half-sib designs
PM Visscher
Genetics Selection Evolution , 1995, DOI: 10.1186/1297-9686-27-4-335
Abstract:
Classical versus new prognostic factors for adjuvant treatment selection based on line software to estimate risk and benefit
PM Ravdin
Breast Cancer Research , 2005, DOI: 10.1186/bcr1224
Abstract: To address this problem the decision tool Adjuvant! (Fig. 1) was created [1,2]. It uses data from national databases and other sources to make estimates of a patient's baseline prognoses. It uses data from the Overview, and individual clinical trials to make estimates of treatment efficacy. It uses national data about age-specific competing mortality to make estimates of competing mortality. Although the program provides these estimates, it has the flexibility to allow the user to modify the estimates as they think appropriate. Over 200 pages of help files allow the user to review the data on which the program is based, and the methods used by the program and the assumptions which it makes. That for the most part these estimates are reasonable is supported by a validation of Adjuvant!'s estimates in a large independent database [3]. Specific sheets describing the toxicity and safety issues of different adjuvant treatment options are included.The presentation will discuss the strengths and limitations of this approach. The major strength is that this tool allows the doctor and patient to review in a quantitative sense the benefits and risk of different options. The limitations are that for many therapies we have limited knowledge about their long-term efficacy (and Adjuvant! makes specific assumptions to deal with this), and undoubtedly we will learn more about how some tumors' characters may affect their sensitivity to therapy. How new prognostic factors and genomic information may be included will be discussed.
Reflexiones sobre la Ley 34/2003 (1): Consideraciones generales sobre las tablas de indemnización de da?os personales
Garamendi,PM;
Cuadernos de Medicina Forense , 2004, DOI: 10.4321/S1135-76062004000200003
Abstract: on november 5 2003 the new law 34/2003 of modification and adaptation to the community normative of the legislation of private insurance which included the modification of chart vi of the scale of compensation of definitive sequels of the law 30/1995 of ordination and supervision of private insurance was published. in our country, the mentioned scale has constituted and constitutes the tool applied in the judicial context for the economic compensation of the lesions taken place on the occasion of traffic accidents. the previous writing of the mentioned scale has been from its beginning the motive inflamed controversies in the different debate forums related with the valuation of corporal damage. without denying the necessity of some instrument of common valuation to collaborate in avoiding the situation of existent apparent chaos in our country until the installation of the traffic scale, there has been much criticism expressed on their scientific foundation, validity and final expression. the present work tries to advance some criticism and proposals for improvement on the new composition of the scale.
Reflexiones sobre la Ley 34/2003 (3): Valoración de los capítulos relativos a raquis, extremidades superiores e inferiores
Garamendi,PM.;
Cuadernos de Medicina Forense , 2004, DOI: 10.4321/S1135-76062004000400001
Abstract: on november 5 2003 the new law 34/2003 was published. this law entails the modification and adaptation to the community normative concerning legislation of private insurance that included the modification of the chart vi of scale of compensation of definitive sequels of the law 30/1995 of ordination and supervision of private insurance. in our country, the mentioned scale has constituted and constitutes the tool applied in the judicial context for economic compensation of the lesions taken place in traffic accidents. the previous writing of the mentioned scale has been the cause of inflamed controversies in the different debate forums related to the valuation of the corporal damage from its installation. without denying the necessity of some instrument of common valuation that collaborates to avoid the situation of existing apparent chaos in our country until the installation of the traffic scale, they have been multiple the criticisms expressed on their scientific basis, validity and final writing. the present paper tries to advance some criticisms and proposals of improvement on the new writing of the scale, being centered on the modifications included in the chapter of spinal column, upper and lower extremities in the locomotor aparatus.
Intertextuality in the Book of Jubilees
PM Venter
HTS Theological Studies/Teologiese Studies , 2007,
Abstract: The second century BCE Book of Jubilees presents the contents of Genesis-Exodus in a new form. This article studies the techniques used in Jubilees 23. It indicates how Psalm 90:10 was used to link the death of Abraham to a declining-inclining scheme of longevity. This scheme was then combined with a heptadic jubilee scheme. To this the author added a Deuteronomistic retributive scheme of sinpunishment- repentance-salvation. On this combination an apocalyptic framework was finally superimposed. HTS Theological Studies Vol. 63 (2) 2007: pp. 463-480
Die huwelik as identiteitsmerker in die Ou Testament
PM Venter
HTS Theological Studies/Teologiese Studies , 2007,
Abstract: Marriage as identity marker in the Old Testament The formularies used for consecrating marriages in the Nederduitsch Hervormde Church reflect this church's view on matrimony. As the biblical bases of the formularies are deficient, new ways of exploring biblical information on this subject should be followed. This article proposes that data on marriage in the Bible always be used in conjunction with other concepts to form theological constructs to outline who God is and who his people are. It is always intended to be an identity marker to the members of the church. In the three Genesis cycles of Genesis 11:10-25:11; 25:12- 35:29 and 36:1-50:26 heirship, marriage and land are used in an integrated construct to indicate the identity of the post-exilic community in Yehud. In the penitential prayers of Ezra 9:6-15 and Nehemia 9:5b-37 the concepts law, land and marriage are jointly used to depict the identity of the “real” Israel. The conclusion drawn from this investigation is that the Bible does not present models for marriage, but rather theological constructs to understand the relationship with the Lord in metaphorical terms and to reflect on the meaning of everyday life of that relationship including matrimony under ever changing social circumstances. HTS Theological Studies Vol. 63 (3) 2007: pp. 1213-1237
Conflict over landownership: The case of farmers and cattle graziers in the northwest region of Cameroon
PM Sone
African Journal on Conflict Resolution , 2012,
Abstract: This article examines the general underlying principles of landownership in Cameroon and the northwest region in particular. It argues that the recurrent conflicts involving farmers and cattle graziers over landownership in the northwest region of Cameroon have their roots in scarcity of land, climate change and the ‘poor’ application of statutory laws guaranteeing landownership. Although some farmers have struggled to enjoy their right to use land, a culture of acknowledging their right to control land during land contention is yet to take hold. In some instances, the laws continue to be disregarded in favour of wealthy cattle graziers against farmers’ right to own land. This study argues that there cannot be peace, tenure, security and stability in the region without some attempt at resolving this perennial phenomenon of land conflict between farmers and cattle graziers. Resolving this problem will require the institution of land reform and some proactive measures to address the region’s landrelated conflicts.
Canon, Intertextuality and History in Nehemiah 7:72b–10:40
PM Venter
HTS Theological Studies/Teologiese Studies , 2009,
Abstract: The forming of the Hebrew Bible can be depicted as an ongoing movement from traditum to traditio. Several parallel and interactive phenomena contributed to this process. One of these was intertextuality, which played a major role in the process. This article indicates that intertextuality was not restricted to mere quotations or the recycling of existing traditum, but also included dialogue with older genres and existing ideological patterns. Aesthetic and polylogic intertextuality are shown to have been part of this process of inner-biblical exegesis. These two aspects of intertextuality are demonstrated in a discussion of the narrative in Nehemiah 7:72b. Aggadic exegesis linked to aesthetic intertextuality is found in several places in this passage. Polylogic intertextuality can be seen in the use of the Gattungen of Historical Review and Penitential Prayer in Nehemiah 9:1–37. These are linked to a Sitz im Leben during the fi fth century BCE when an endeavour was made to fi nd a new identity for the Judaeans.
Congruent ethos in the Second Temple literature of the Old Testament
PM Venter
HTS Theological Studies/Teologiese Studies , 2011,
Abstract: Proposing the term ‘congruent ethos’ for studying Old Testament ethics, this article indicates (in line with existing research) that opposing ethical viewpoints are found in the Old Testament. The modus operandi followed was firstly to compare the penitential prayer in Daniel 9:4–19 with those in Ezra 9:6–15 and Nehemiah 9:6–37. This comparison shows that the phenomenon of conflicting ethics was present in Yehud during the Second Temple period. Whilst the Daniel text reflects a more universal attitude, the penitential prayers in Ezra and Nehemiah propose a nationalist view of God and an exclusivist identity for Israel. Although Daniel can be dated later than Ezra-Nehemiah, the tendency to juxtapose an exclusivist viewpoint with an inclusivist one was already present in the earlier period of the Second Temple. This is evidenced by the literature of Isaiah 56–66, Ruth, Jonah, Esther, Tobit, Judith and even Joshua.
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