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Search Results: 1 - 10 of 31 matches for " PLEURISY "
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Pleuresia inflamatoria en la infancia: Conducta quirúrgica
Delgado Delgado,Arturo L.; Elizechea Hernández,ángel; Medina Vic,Lucrecia; Ponce Sandoval,Nelson;
Revista Cubana de Pediatr?-a , 2003,
Abstract: pneumonia complicated due to pleurisy has always been a process affecting morbidity and mortality at the pediatric age and on ocassions some surgical procedure has been necessary. the initial decision wether to perform only a pleural puncture or to add a minimum pleurotomy may be controversial. that's why it was decided to conduct a study of all the children that were admitted at the pediatric teaching hospital of san miguel del padrón with pneumonia complicated due to inflammatory pleurisy (pleurisy during an inflammatory pulmonary process) and that underwent surgery to resolve the effusion from january 2000 to january 2001.the medical histories of the 10 patients were studied. tables were made and figures were obtained. the age group 1-5 was the most affected with 40 %. no sex preponderance was observed and the most frequent localization of the inflammatory process (90 %) was the right lung and, within this, the right basis with 40 %. 50 % of the patients underwent only pleural puncture and in the other half pleurotomy was performed, too. 30 % of this last group had more than 150 ml in the initial puncture. a minimum pleurotomy was necessary in 5 patients. la neumonía complicada por pleuresía ha sido siempre un proceso que ha afectado la morbilidad y mortalidad en la edad pediátrica y en ocasiones necesita de algún proceder quirúrgico para su solución. la decisión inicial de si realizar solo una punción pleural o agregarle una pleurostomía mínima, puede ser controversial, por lo que se decidió realizar un estudio de todos aquellos ni?os que fueron ingresados en el hospital pediátrico universitario de san miguel del padrón con neumonía complicada por pleuresía inflamatoria (pleuresía durante un proceso inflamatorio pulmonar), a los cuales hubo que realizarles algún proceder quirúrgico para la solución de su derrame, en el período de enero de 2000 a enero de 2001; se estudiaron los expedientes clínicos de 10 pacientes; se les conformaron tablas y figuras. el grupo d
Pleuresia inflamatoria en la infancia: Conducta quirúrgica
Arturo L. Delgado Delgado,ángel Elizechea Hernández,Lucrecia Medina Vic,Nelson Ponce Sandoval
Revista Cubana de Pediatr?-a , 2003,
Abstract: La neumonía complicada por pleuresía ha sido siempre un proceso que ha afectado la morbilidad y mortalidad en la edad pediátrica y en ocasiones necesita de algún proceder quirúrgico para su solución. La decisión inicial de si realizar solo una punción pleural o agregarle una pleurostomía mínima, puede ser controversial, por lo que se decidió realizar un estudio de todos aquellos ni os que fueron ingresados en el Hospital Pediátrico Universitario de San Miguel del Padrón con neumonía complicada por pleuresía inflamatoria (pleuresía durante un proceso inflamatorio pulmonar), a los cuales hubo que realizarles algún proceder quirúrgico para la solución de su derrame, en el período de enero de 2000 a enero de 2001; se estudiaron los expedientes clínicos de 10 pacientes; se les conformaron tablas y figuras. El grupo de edad más afectado fue el de 1 a 5 a os con un 40 %. El sexo no tuvo preponderancia y la localización más frecuente del proceso inflamatorio (90 %) fueron el pulmón derecho, y entre estas la base derecha con un 40 %. Al 50 % de los pacientes se le realizó solamente una punción pleural y a la otra mitad se le a adió una pleurostomía, y tenía el 30 % en este último grupo más de 150 mL en la punción inicial; a 5 pacientes hubo que realizarles una pleurostomía mínima. Con estos resultados se consideró que en el momento de la punción pleural inicial el hallazgo macroscópico de aspecto fibrino purulento es indicativo de pleurostomía, así como este aspecto en el líquido de una segunda punción de ser necesario ésta y una celularidad mayor de 175 ′ 106, y una glucosa menor de 1 mmol/L en el microscópico del líquido de la primera, si se hace necesario realizar una segunda punción o los mismos resultados del líquido proveniente de esta segunda o cualquier otra punción. Pneumonia complicated due to pleurisy has always been a process affecting morbidity and mortality at the pediatric age and on ocassions some surgical procedure has been necessary. The initial decision wether to perform only a pleural puncture or to add a minimum pleurotomy may be controversial. That's why it was decided to conduct a study of all the children that were admitted at the Pediatric Teaching Hospital of San Miguel del Padrón with pneumonia complicated due to inflammatory pleurisy (pleurisy during an inflammatory pulmonary process) and that underwent surgery to resolve the effusion from January 2000 to January 2001.The medical histories of the 10 patients were studied. Tables were made and figures were obtained. The age group 1-5 was the most affected with 40 %. No sex preponderance
Analysis of 128 Cases With Tuberculous Pleurisy
Levent Aky?ld?z,Tekin Y?ld?z,Güng?r Ate?,Baran Gündo?u?
Dicle Medical Journal , 2007,
Abstract: In our country, most common form of extrapulmonary tuberculosis is tuberculous pleurisy. The mean age of patients is increasing to older age in developed countries in last 50 years but tuberculosis is still the illness of early ages in developing countries. We aimed to evaluate retrospectively clinical, radiological and laboratory findings and diagnostic methods of 128 patients with tuberculous pleurisy who were diagnosed as tuberculosis, between 1999 and 2005 in this study. Seventy six patients of all (%59) were males and fifty two cases were females(41%) and mean age of all patients was 39±12 (15-74) year. Pleural adenosine deaminase level was evaluted in 19 patients and mean level of them was 62±23.7 IU/L. Most common symptoms were chest pain and cough. Tuberculosis pleurisy was unilateral in 97.6% of patients. Parenchymal infiltration on Chest X-ray was observed in 18 % of cases. Most common diagnostic method was (used) pleural biopsy in 82% of patients. In conclusion, tuberculosis pleurisy is usually the diseases of young adults. In almost all of the patients, pleural effusion was unilateral and closed pleural biopsy presented high rates of diagnosis in a short time.
Genetic Association of Interferon Gamma Induced Protein-10 (IP-10), CXCL-10 Gene Polymorphisms with TB Pleurisy Susceptibility in South Indian Population  [PDF]
Ghousunnissa Sheikh, Venkata Sanjeev Kumar Neela, Satya Sudheer Pydi, Naveen Chandra Suryadevara, Ramulu Gaddam, Suman Latha Gaddam, Sai Kumar Auzumeedi, Vijaya Lakshmi Valluri
Open Journal of Immunology (OJI) , 2015, DOI: 10.4236/oji.2015.52008
Abstract: CXCL-10 known as Interferon gamma-induced protein 10 (IP-10) or small-inducible cytokine 10 is a 8.7 kDa protein, which is secreted in response to IFN-γ by monocytes, endothelial cells and fi-broblasts. It has chemo-attraction for monocytes/macrophages, T cells, NK cells and dendritic cells in promotion of T cell adhesion to endothelial cells. In the present study, we investigated whether polymorphisms in CXCL-10 gene have any role in the manifestation of Tuberculous (TB) pleurisy. Two SNPs in CXCL-10 promoter region (1447A > G and 135G > A) were genotyped in patients with TB Pleurisy (n = 186), Pulmonary TB patients (n = 159) and healthy controls (n = 205) by PCR-RFLP. Disease associations were statistically analyzed by Fisher exact test. At the 135G > A position, the frequencies of genotype GA and allele G were significantly high in TB pleurisy patients compared to healthy controls. While the frequencies of genotype AA and allele A were significantly low in TB pleurisy patients compared to healthy controls. The frequency of haplotype A-G with the combination of 1447A > G and 135G > A was significantly high in TB pleurisy. Our results reveal that genotype GA and allele G at 135G > A position were strongly associated with susceptibility to tuberculous pleurisy. The GA genotype may be a useful genetic marker for early detection of the disease in high risk individuals.
Modulatory role of eosinophils in allergic inflammation: new evidence for a rather outdated concept
Bandeira-Melo, Christianne;Cordeiro, Renato SB;Silva, Patrícia MR;Martins, Marco A;
Memórias do Instituto Oswaldo Cruz , 1997, DOI: 10.1590/S0074-02761997000800007
Abstract: the eosinophilic response has been identified as a key alteration in the pathogenesis of asthma and other allergic diseases. a close-correlation between disease severity and eosinophilia, and the eosinophil ability to provide toxic and pro-inflammatory agents are the major elements supporting the interpretation that there is indeed a causal relationship between these phenomena. nevertheless, controversy still persists since some studies have clearly demonstrated that eosinophil infiltration is not necessarily accompanied by tissue damage or hyperresponsiveness. in addition, there are some examples in the literature in which such alterations are not modified following abrogation of eosinophil influx. in this review it will be argued, based on a model of ige-dependent pleurisy, that eosinophil infiltration can be associated with down-regulation of allergic inflammatory response. the potential mechanism by which eosinophils could be acting as a immunomodulatory cells in this particular system will also be assessed.
Modulatory role of eosinophils in allergic inflammation: new evidence for a rather outdated concept
Bandeira-Melo Christianne,Cordeiro Renato SB,Silva Patrícia MR,Martins Marco A
Memórias do Instituto Oswaldo Cruz , 1997,
Abstract: The eosinophilic response has been identified as a key alteration in the pathogenesis of asthma and other allergic diseases. A close-correlation between disease severity and eosinophilia, and the eosinophil ability to provide toxic and pro-inflammatory agents are the major elements supporting the interpretation that there is indeed a causal relationship between these phenomena. Nevertheless, controversy still persists since some studies have clearly demonstrated that eosinophil infiltration is not necessarily accompanied by tissue damage or hyperresponsiveness. In addition, there are some examples in the literature in which such alterations are not modified following abrogation of eosinophil influx. In this review it will be argued, based on a model of IgE-dependent pleurisy, that eosinophil infiltration can be associated with down-regulation of allergic inflammatory response. The potential mechanism by which eosinophils could be acting as a immunomodulatory cells in this particular system will also be assessed.
内科胸腔镜治疗结核性胸膜炎的意义*
唐晓媛,左慧敏,陈国峰,李杰,文慧兰
- , 2018, DOI: 10.3969/j.issn.1007-1989.2018.07.001
Abstract: 摘要: 分析内科胸腔镜治疗结核性胸膜炎的临床意义。方法?收集该院40例诊断为结核性胸膜炎的患者,其中由内科胸腔镜下确诊结核性胸膜炎患者为20例,纳为治疗组;由常规胸腔穿刺后通过胸水化验、结核菌素试验而临床诊断为结核性胸膜炎患者20例,纳为对照组;两组诊断后均给予了相同抗结核方案治疗。计算两组患者住院天数,统计治疗组、对照组住院期间共行的胸腔穿刺数;测量两组患者治疗12个月后的胸部CT上胸膜肥厚度。结果?治疗组和对照组的平均住院天数分别为(9.55±1.63)和(13.60±3.59)d, 治疗组明显短于对照组,两组比较差异有统计学意义(P?<0.05);治疗组与对照组平均行胸腔穿刺术次数为(1.50±0.76)和(2.80±0.99)次,治疗组明显少于对照组,两组比较差异有统计学意义(P?<0.05)。治疗组与对照组治疗12个月后的胸膜CT上平均胸膜肥厚度分别为(0.15±0.09)和(2.30±0.13)mm,治疗组明显薄于对照组,两组比较差异有统计学意义(P?<0.05)。结论?使用内科胸腔镜下确诊结核性胸膜炎的患者,可减少住院日,减少胸腔穿刺频次,减少胸膜肥厚度。临床上若疑诊结核性胸膜炎者,建议优先考虑行内科胸腔镜诊治。
Abstract: To analyze the clinical significance of thoracoscopy in treatment of tuberculous pleurisy. ?Methods?We collected 40 cases of tuberculous pleurisy as research objects, 20 patients as treatment groups were diagnosed with tuberculous pleurisy by medical thoracoscopy, while the other 20 patients as control groups, diagnosed by hydrothorax test and tuberculin test by conventional thoracic puncture. Patients in both groups were treated with the same antituberculosis treatment. The hospitalization days and the thoracic puncture times of the two groups was calculated. Then measure the thickness of the pleural fertilizer by chest CT after 12 months of treatment.?Results?There was a statistical difference of the average hospitalization days between the treatment group (9.55?±?1.63)?d and the control group (13.60?±?3.59)?d, P?
Valor diagnóstico da pun??o-biópsia pleural: experiência em um servi?o de clínica médica
TRAJMAN, ANETE;BELO, MARCIA TERESA;TEIXEIRA, ELENY GUIMAR?ES;BELO NETO, EPAMINONDAS;RODRIGUES, DEBORA FERNANDES;CASTELLO BRANCO, MARIO MONJARDIM;
Jornal de Pneumologia , 2001, DOI: 10.1590/S0102-35862001000100004
Abstract: objective: to evaluate the efficacy of thoracentesis and pleural biopsy in the diagnosis of pleural inflammatory diseases. methods: a retrospective study of 82 thoracenteses performed over a 42-month period in an internal medicine ward in rio de janeiro was conducted. biochemical, cytological, and microbiological features of the pleural effusion, as well as the histopathological examination of the pleural tissue, were analyzed according to the final diagnosis. the sensitivity, sensibility, and predictive efficacy in the diagnosis of tuberculosis were calculated using different cut-off values of protein concentration and lymphocyte percentage. results: of the 82 patients, 73 (89%) had tuberculosis. this was the only diagnosis among patients aged 35 years or less. the negative predictive value (pv) raised from 17.1% to 66.7% when 4.5 and 2.5 g/dl, respectively, were used as cut-off values for protein concentration in the pleural fluid. using 70% as the cut-off value for lymphocyte percentage in pleural fluid, negative pv was 100% and positive pv was 94.2%. acid fast bacilli staining of the pleural fluid was negative in all samples. the sensitivity of the histopathological examination of the pleural tissue was 69.2% for the diagnosis of tuberculosis. conclusions: tuberculosis was the most common cause of pleural effusion in all age groups. histopathological examination had the highest sensitivity to confirm tuberculosis. the authors suggest that, in populations with a high prevalence of tuberculosis, pleural tissue biopsy should be performed simultaneously with thoracentesis.
Antigen-induced pleural eosinophilia is suppressed in diabetic rats: role of corticosteroid hormones
Diaz, Bruno L;Serra, Magda F;Barreto, Emiliano O;Cordeiro, Renato SB;Martins, Marco A;Silva, Patricia MR e;
Memórias do Instituto Oswaldo Cruz , 1997, DOI: 10.1590/S0074-02761997000800031
Abstract: previous studies have evidenced for the existence of interactive regulatory mechanisms between insulin and steroid hormones in different systems. in this study, we have investigated whether endogenous corticosteroids could be implicated in the hyporeactivity to antigen challenge observed in sensitized diabetic rats. alloxinated rats showed a long-lasting increase in the blood glucose levels and a reduction in the number of pleural mast cells at 48 and 72 hr, but not at 24 hr after alloxan administration. in parallel, they also showed a significant elevation in the plasma levels of corticosterone together with an increase in the adrenal/body weight ratio. antigen-evoked eosinophil accumulation appeared significantly reduced in rats pretreated with dexamethasone as well as in those rendered diabetic 72 hr after alloxan. in the same way, naive animals treated with dexamethasone also responded with a significant decrease in the number of pleural mast cells. interestingly, when sensitized diabetic rats were pretreated with the steroid antagonist ru 38486 a reversion of the reduction in the allergen-induced eosinophil accumulation was noted. we conclude that the down-regulation of the allergic inflammatory response in diabetic rats is close-related to reduction in mast cell numbers and over expression of endogenous corticosteroids.
The Effect of Two Extracts from Stichopus badionotus Selenka upon Induced Pleurisy in Rat
S.Z. Idid,D.M. Jalaluddin,B.H. Ridzwan,A. Bukhori
Pakistan Journal of Biological Sciences , 2001,
Abstract: The pleurisy model in rats was used to study the pharmacology of extracts from the sea-cucumber Stichopus badionotus Selenka. Ten control animals were injected intrapleurally with 0.1ml carageenan (1%) and their pleural cavities were examined. Three groups (six animals per group) were treated with concentrations of 5, 10 and 20 mg/ml of the ethanol extract of sea-cucumber given i.p. and three other groups were treated with similar concentrations of a phosphate-buffer extract also given i.p. A half-hour later the animals were administered carageenan (i.p.). These animals were killed four-hours after the administration of carageenan and their pleural cavities were examined. The results showed that the extracts were able to reduce pleural effusion, neutrophil counts, and also adenosine deaminase activity significantly and in a dose-dependent manner. The effects were more pronounced with ethanol extract compared to the phosphate-buffer extract.
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