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Search Results: 1 - 10 of 665006 matches for " P. R. M.;Carvalho "
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Biphasic modulation of insulin receptor substrate-1 during goitrogenesis
Grozovsky, R.;Morales, M.M.;Carvalho, D.P.;
Brazilian Journal of Medical and Biological Research , 2007, DOI: 10.1590/S0100-879X2006005000090
Abstract: insulin receptor substrate-1 (irs-1) is the main intracellular substrate for both insulin and insulin-like growth factor i (igf-i) receptors and is critical for cell mitogenesis. thyrotropin is able to induce thyroid cell proliferation through the cyclic amp intracellular cascade; however, the presence of either insulin or igf-i is required for the mitogenic effect of thyroid-stimulating hormone (tsh) to occur. the aim of the present study was to determine whether thyroid irs-1 content is modulated by tsh in vivo. strikingly, hypothyroid goitrous rats, which have chronically high serum tsh levels (control, c = 2.31 ± 0.28; methimazole (mmi) 21d = 51.02 ± 6.02 ng/ml, n = 12 rats), when treated with 0.03% mmi in drinking water for 21 days, showed significantly reduced thyroid irs-1 mrna content. since goiter was already established in these animals by mmi for 21 days, we also evaluated irs-1 expression during goitrogenesis. animals treated with mmi for different periods of time showed a progressive increase in thyroid weight (c = 22.18 ± 1.21; mmi 5d = 32.83 ± 1.48; mmi 7d = 31.1 ± 3.25; mmi 10d = 33.8 ± 1.25; mmi 14d = 45.5 ± 2.56; mmi 18d = 53.0 ± 3.01; mmi 21d = 61.9 ± 3.92 mg, n = 9-15 animals per group) and serum tsh levels (c = 1.57 ± 0.2; mmi 5d = 9.95 ± 0.74; mmi 7d = 10.38 ± 0.84; mmi 10d = 17.72 ± 1.47; mmi 14d = 25.65 ± 1.23; mmi 18d = 35.38 ± 3.69; mmi 21d = 31.3 ± 2.7 ng/ml, n = 9-15 animals per group). thyroid irs-1 mrna expression increased progressively during goitrogenesis, being significantly higher by the 14th day of mmi treatment, and then started to decline, reaching the lowest values by the 21st day, when a significant reduction was detected. in the liver of these animals, however, a significant decrease of irs-1 mrna was detected after 14 days of mmi treatment, a mechanism probably involved in the insulin resistance that occurs in hypothyroidism. the increase in irs-1 expression during goitrogenesis may represent an important event associated wi
Effects of Five Years Adoption of No-Tillage Systems for Vegetables Crops in Soil Organic Matter Contents  [PDF]
Carlos E. P. Lima, ítalo M. R. Guedes, Juscimar da Silva, Flávia A. Alcantara, Nuno R. Madeira, Agnaldo D. F. Carvalho, Mariana R. Fontenelle
Agricultural Sciences (AS) , 2018, DOI: 10.4236/as.2018.91009
Abstract: Vegetables productions systems are done normally with intense soil tillage causing a strong decline of soil quality. Use of conservation systems can be an alternative to recover this quality. In order to evaluate the effects of such systems on soil organic matter, an experiment has been conducted in randomized blocks design and factorial scheme 3 × 2: three soil management systems (no-tillage; reduced tillage and conventional tillage) and two cover crops (maize single; and intercropping maize with gray velvet bean—Stizolobium niveum); and repeated measures over time. Soil samples were collected before the implementation of the experiment and at the end of each crop cycle until the fifth crop cycle. Carbon associated with humic substances is also determined in 0 - 5 cm, 5 - 10 cm and 10 - 30 cm at the end of the last crop cycle. The SOM content was higher in RT (48.34 g·kg-1) than in the CT (39.48 g·kg-1) at the end of the fifth crop cycle. SOM content in NT (44.92 g·kg-1) was statistically equal to RT and CT, during the same period. In 0 - 5 cm, carbon contents associated to the humic substances present the same behavior of SOM contents in 0 - 10 cm. Probably these results are associated with the capacity of each system to improve superficial contents of SOM stable fractions. It follows that the conservation systems used are alternatives to the cultivation vegetables in order to improve soil organic matter contents.
Electronic properties, doping and defects in chlorinated silicon nanocrystals
A. Carvalho,S. ?berg,M. J. Rayson,P. R. Briddon
Physics , 2011, DOI: 10.1103/PhysRevB.86.045308
Abstract: Silicon nanocrystals with diameters between 1 and 3 nm and surfaces passivated by chlorine or a mixture of chlorine and hydrogen were modeled using density functional theory, and their properties compared with those of fully hydrogenated nanocrystals. It is found that fully and partially chlorinated nanocrystals are stable, and have higher electron affinity, higher ionization energy and lower optical absorption energy threshold. As the hydrogenated silicon nanocrystals, chlorinated silicon nanocrystals doped with phosphorus or boron require a high activation energy to transfer an electron or hole, respectively, to undoped silicon nanocrystals. The electronic levels of surface dangling bonds are similar for both types of surface passivation, although in the chlorinated silicon nanocrystals some fall outside the narrower energy gap.
Tratamiento quirúrgico de duplicidad peneana completa
Carvalho,A.P.; Ramires,R.; Soares,J.; Carvalho La Fuente,; Filinto,M.;
Actas Urológicas Espa?olas , 2008, DOI: 10.4321/S0210-48062008000900014
Abstract: penile duplication is a rare anomaly with an incidence of 1 in 5,500,000. it is almost associated with other malformations like double bladder, presence of the cloaca, imperforate anus, duplication of the recto sigmoid and vertebral deformities. the authors present the surgical technique to resolve a rare case of complete penile duplication in a 4 years old child, without any other malformation.
Use of thin films obtained by plasma polymerization for grain protection and germination enhancement
Carvalho Rodrigo A. M.,Carvalho Alexsander T.,Silva Maria Lúcia P. da,Demarquette Nicole R.
Química Nova , 2005,
Abstract: In this work, preliminary results of the use of hydrophobic thin films obtained by plasma deposition to protect grains and seeds are presented: grains coated by the films did not present biological degradation when stored in a saturated water vapor environment, but had their germination accelerated in the presence of water. A model that explains the difference of behavior of the films when exposed to water in vapor form or in liquid form, based on the formation of microchannels within the film that lead to water uptake in seeds, is presented. The model was successfully tested using quartz crystal measurements, which showed that the microchannels within the films can favor the adsorption and permeation of water when the films are immersed in water.
Chemical Screening of Urochloa humidicola: Methods for Characterizing Secondary Metabolites and Allelopathic Activity on Forage Legumes  [PDF]
R. C. Ribeiro, M. G. de Carvalho, M. de L. L. de Moraes, R. O. P. Rossiello, D. R. de Oliveira, R. M. Q. de Amorim, E. Barbieri Junior
American Journal of Plant Sciences (AJPS) , 2018, DOI: 10.4236/ajps.2018.96093
Abstract: The aim of this study was to identify the main classes of secondary metabolites present in the root and shoot crude extracts and fractions from the forage grass Urochloa humidicola (Rendle) Morrone & Zuloaga and to evaluate the allelopathic effect of these metabolites on forage legumes for intercropping. Phytochemical prospecting analyses, 1H NMR and capillary electrophoresis were performed on extracts of U. humidicola. Allelopathic activity was evaluated in germination of Stylosanthes, Macrotyloma axillare and Lactuca sativa L. (standard) in the presence of crude extracts, isolated saponins, flavonoids and trans-cinnamic acid. The metabolite classes present in the extracts could be determined by the combined use of the tested analytical techniques, but their use alone was usually not sufficient to chemically characterize the species. Capillary electrophoresis was effective in detecting phenolic compounds. Macrotyloma axillare was tolerant to crude extracts of U. humidicola. Saponins and trans-cinnamic acid, but not the flavonoids, reduced germination of the target plants.
Comparison of NCHS, CDC and WHO growth charts in the nutritional assessment of hospitalized children up to five years old
Silveira,C. R. M.; Beghetto,M. G.; Carvalho,P. R. A.; Mello,E. D.;
Nutrición Hospitalaria , 2011,
Abstract: aims: this study evaluated the agreement of growth charts proposed by the national center for health statistics (nchs/1977), centers for disease control and prevention (cdc/2000) and world health organization (who/2006). methods: were assessed children between 0 and 5 years old, hospitalized in the pediatric wards of a brazilian school hospital. z-score indexes: stature/age (s/a), weight/age (w/a) and weight/stature (w/s) was evaluated, in each of the three references (nchs, cdc and who). anova and test bland & altman and lin plots were used in the comparison of the 3 charts. the agreement of the nutritional state categories was also evaluated, through kappa coefficient. the study was approved by the institution's research ethics committee. results: the study analyzed 337 children, whose median age was 0.52 (iqr: 0.21-1.65) years, 65.3% of them were below 1 year old, 60.2% were male and 50% hospitalized due to acute respiratory disease. lower z-scores of w/a and s/a were obtained with the who charts and lower w/s with the cdc chart. high correlation and agreement were observed among the criteria, but more patients were classified as presenting shortness through the who criteria. cdc and who criteria were more rigorous than the nchs criteria for the diagnosis of underweight (w/a) and malnutrition (w/s). conclusion: despite the strong agreement of the 3 charts, the adoption of the who charts seems to be more helpful for the children's nutritional screening for admission, as it enables to detect a higher number of malnourished children or at nutritional risk, who will benefit from an early intervention.
Comparison of NCHS, CDC and WHO growth charts in the nutritional assessment of hospitalized children up to five years old Comparación de las curvas de crecimiento del NCHS, CDC y la OMS en la valoración nutricional de los ni os hasta cinco a os hospitalizados
C. R. M. Silveira,M. G. Beghetto,P. R. A. Carvalho,E. D. Mello
Nutrición Hospitalaria , 2011,
Abstract: Aims: This study evaluated the agreement of growth charts proposed by the National Center for Health Statistics (NCHS/1977), Centers for Disease Control and Prevention (CDC/2000) and World Health Organization (WHO/2006). Methods: Were assessed children between 0 and 5 years old, hospitalized in the pediatric wards of a Brazilian school hospital. Z-score indexes: stature/age (S/A), weight/age (W/A) and weight/stature (W/S) was evaluated, in each of the three references (NCHS, CDC and WHO). ANOVA and test Bland & Altman and Lin plots were used in the comparison of the 3 charts. The agreement of the nutritional state categories was also evaluated, through kappa coefficient. The study was approved by the Institution's Research Ethics Committee. Results: The study analyzed 337 children, whose median age was 0.52 (IQR: 0.21-1.65) years, 65.3% of them were below 1 year old, 60.2% were male and 50% hospitalized due to acute respiratory disease. Lower Z-scores of W/A and S/A were obtained with the WHO charts and lower W/S with the CDC chart. High correlation and agreement were observed among the criteria, but more patients were classified as presenting shortness through the WHO criteria. CDC and WHO criteria were more rigorous than the NCHS criteria for the diagnosis of underweight (W/A) and malnutrition (W/S). Conclusion: Despite the strong agreement of the 3 charts, the adoption of the WHO charts seems to be more helpful for the children's nutritional screening for admission, as it enables to detect a higher number of malnourished children or at nutritional risk, who will benefit from an early intervention. Objetivo: Este estudio comparó las curvas de crecimiento para la clasificación de la puntuación Z de talla/edad (T/E), peso/edad (P/E) y peso/talla (P/T) propuesto por el Centro Nacional para Estadísticas Sanitarias (NCHS, 1977), Centers for Disease Control and Prevention (CDC/2000) y la Organización Mundial de la Salud (OMS/2006). Métodos: Ni os entre 0 y 5 a os de edad hospitalizados en las salas de pediatría de un hospital terciario en Brazil fueron valorados. Se utilizaron ANOVA, Bland & Altman y gráfico de Lin en la comparación de las 3 curvas de crecimiento. Las categorías del estado nutricional se evaluaron por coeficiente kappa. El estudio fue aprobado por el Comité de ética de la institución. Resultados: El estudio analizó 337 ni os, cuya edad fue 0,52 (IQ: 0,21-1,65) a os, 65,3% de ellos eran menores de 1 a o de edad, 60,2% eran varones y 50% con enfermedades respiratorias agudas. Se obtuvieron puntuaciones Z más bajas de P/E y T/E con la curva de
Amphibia, Anura, Hylidae, Dendropsophus pseudomeridianus: Distribution extension and geographic distribution map.
Silva, G. R.,Carvalho-e-Silva, S. P.,Carvalho-e-Silva, A. M. P. T.
Check List , 2008,
Abstract:
Importantes características de chuva para a conserva??o do solo e da água no município de S?o Manuel (SP)
Moreti, D.;Carvalho, M. P.;Mannigel, A. R.;Medeiros, L. R.;
Revista Brasileira de Ciência do Solo , 2003, DOI: 10.1590/S0100-06832003000400016
Abstract: mathematical models for soil erosion prediction are of unquestionable validity for planning the use of agricultural soils. the universal soil loss equation (usle) is an example of such models and estimates the expected annual mean losses of soil in a given site and for a given management system based on the parameters: rain erosivity (r), soil erodibility (k), slope length (l), steepness (s), soil cover and management (c), and conservation practices (p). with the objective of contributing to conservation planning in the use of local soils, the rain erosivity factor (r) of the usle was estimated in simplified form for a 49 year daily rain series in the county of s?o manuel, brazil (22 o 45 ' s latitude; 48 o 30 ' w longitude). besides, the return period, frequency of occurrence of the annual rain erosivity indexes, and the maximum daily rain values for the calculation of canal dimension of agricultural level terraces were also calculated. the calculated value of parameter r was 7,487 mj mm ha-1 h -1 year-1, expected to occur at least once every 2.33 years at the site with a probability of 42.92%. a concentration of 81.48% of the total r value was observed from october through march, indicating that the greatest part of the annual erosion soil losses are expected to occur during this period. the values of the annual ei30 indexes for return periods of 2 , 5 , 10 , 20 , 50 , and 100 years, were 7,216; 8,675; 9,641; 10,568; 11,768 and 12,667 mj mm ha-1 h -1 year-1, respectively. maximum daily rain quantities were 73, 98, 115, 131, 151 and 167 mm, respectively, for the same return periods.
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