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Search Results: 1 - 10 of 95 matches for " Oussama Zghari "
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Effect of Chronic Aluminum Administration on Affective and Cognitive Behavior in Male and Female Rats  [PDF]
Oussama Zghari, Ayoub Rezqaoui, Sihame Ouakki, Mouloud Lamtai, Jihane Chaibat, Abdelhalem Mesfioui, Aboubaker El Hessni, El-Housseine Rifi, Azzouz Essamri, Ali Ouichou
Journal of Behavioral and Brain Science (JBBS) , 2018, DOI: 10.4236/jbbs.2018.84012
Abstract: In this study, we investigated the effect of chronic exposure of low doses of Aluminum on affective and cognitive disorders in male and female rats. Twenty-five rats for each gender are used and the treatment carried out for 8 weeks. Animals received distilled water for control or an intraperitoneal injection of different doses of Aluminum: 0.125, 0.25, 0.5 and 1 mg/kg. Behavioral performance is measured in various tests mainly the Open Field, Elevated Plus Maze, Force Swimming Test, Morris Water Maze, Y-maze and Object Recognition Test. Al exerts anxiogenic properties and depressive effect. The effect begins at 0.25 mg/kg to reach a maximum at 1 mg/kg. In addition, chronic exposure to Aluminum causes cognitive disorders characterized by affection of memory and influence spatial learning performance. The effect of Aluminum on working memory is effective just at 1 mg/kg, while the effect on spatial learning performance begins at 0.25 mg/kg to reach a maximum at 1 mg/kg. In conclusion, Aluminum enhances anxiety and depression parameters and cognitive disorders characterized by the affection of memory and spatial learning performance.
Modulation of Anxiolytic-Like and Antidepressant-Like Effects of Melatonin by Imipramine in Wistar Rats: Possible Interaction with Central Monoaminergic Systems  [PDF]
Sihame Ouakki, Oussama Zghari, Aboubaker El Hessni, Abdelhalem Mesfioui, Ali Ouichou
Neuroscience & Medicine (NM) , 2019, DOI: 10.4236/nm.2019.102008
Abstract: Our current study aims to explore the interaction of melatonin (MEL) with the monoaminergic system on the pathophysiology of affective disorders in Wistar rats. We mention here that, the role of monoaminergic transmission in the pathophysiology of affective disorders in humans is demonstrated in most recent reports. In this sense, our current work aims to explore the effect of melatonin (MEL) with or without imipramine (IMP) on levels of depression and anxiety in Wistar rats and would determine the role of MEL in modulating serotonin, noradrenaline and dopamine neurotransmission. From this point, twenty-four female Wister rats were divided into 4 groups of 6 animals and received subcutaneously during 4 weeks different doses of MEL (4 mg/kg), IMP (2 mg/kg) or MEL (4 mg/kg) + IMP (2 mg/kg). Behavioral performance especially anxiety and depression is measured in the open field (OFT), elevated plus maze (EPM) and forced swim test (FST). The anxiety-like and antidepressant-like effects were observed with MEL at 4 mg/Kg and IMP at 2 mg/Kg but the potentiating effect was more observed with the two combined molecules (MEL and IMP), since locomotors activity assessed by the OFT and EPM was not affected. These effects suggest that psychopharmacological actions of MEL are due, at least in part, to its ability to potentiate the central monoaminergic transmitter effects.
Affective Behavior Dysregulation Was Induced by Chronic Administration of Copper in Wistar Rats  [PDF]
Mouloud Lamtai, Sihame Ouakki, Oussama Zghari, Abdelhalem Mesfioui, Aboubaker El Hessni, Ali Ouichou
Neuroscience & Medicine (NM) , 2019, DOI: 10.4236/nm.2019.102009
Abstract: As both deficiency and excess of copper (Cu) can be harmful, dysregulation in its homeostasis has been connected with various neurological disorders. The present study was undertaken to examine whether Cu chronic administration can induce alterations of affective behavior especially anxiety and depression levels in male and female rats. Twenty-four rats, for each gender, divided in control and three test groups (n = 6), were injected intraperitoneally with saline (0.9% NaCl) or CuCl2 (0.25 mg/kg, 0.5 mg/kg and 1 mg/kg) for 8 weeks. After treatment period, animals were tested in the open-field, elevated plus maze tests for anxiety-like behavior, and forced swimming test for depression-like behavior. Results demonstrated that Cu administered chronically, exerts an anxiogenic effect in rats. In the OFT, Cu decreases the TCA and NRC parameters without modifying the locomotor activity represented by the NTS parameter. With regard to EPM, Cu decreases TOA and EOA parameters without modifying the TAE parameter. A significant increase in depression-like symptoms was also exhibited by Cu treated rats (p < 0.001). A dose of 1 mg/kg CuCl2 showed maximum anxiety-like and depression-like symptoms as compared to controls as well as from the other two doses indicating dose-dependent effects of chronic Cu administration. Overall, these results suggest that intoxication with Cu has potentially deleterious effects on brain as reflected in behavioral dysfunctions such as depression and anxiety.
Fixed points of endomorphisms and relations between metrics in preGarside monoids
Oussama Ajbal
Mathematics , 2014,
Abstract: Rodaro and Silva proved that the fixed points submonoid and the periodic points submonoid of a trace monoid endomorphism are always finitely generated. We show that for finitely generated left preGarside monoids, that includs finitely generated preGarside monoids, Garside monoids and Artin monoids, the fixed and periodic points submonoids of any endomorphism are also finitely generated left preGarside monoids under some condition, and in the case of Artin monoids, these submonoids are always Artin monoids too. We also prove algebraically some inequalities, equivalences and non-equivalences between three metrics in finitely generated preGarside monoids, and especially in trace monoids and Garside monoids.
Towards Efficient OpenMP Strategies for Non-Uniform Architectures
Oussama Tahan
Computer Science , 2014,
Abstract: Parallel processing is considered as todays and future trend for improving performance of computers. Computing devices ranging from small embedded systems to big clusters of computers rely on parallelizing applications to reduce execution time. Many of current computing systems rely on Non-Uniform Memory Access (NUMA) based processors architectures. In these architectures, analyzing and considering the non-uniformity is of high importance for improving scalability of systems. In this paper, we analyze and develop a NUMA based approach for the OpenMP parallel programming model. Our technique applies a smart threads allocation method and an advanced tasks scheduling strategy for reducing remote memory accesses and consequently their extra time consumption. We implemented our approach within the NANOS runtime system. A set of tests was conducted using the BOTS benchmarks and results showed the capacity of our technique in improving the performance of OpenMP applications especially those dealing with a large amount of data.
Creation of Virtual Wi-Fi Access Point and Secured Wi-Fi Pairing, through NFC  [PDF]
Oussama Stiti, Othmen Braham, Guy Pujolle
Int'l J. of Communications, Network and System Sciences (IJCNS) , 2014, DOI: 10.4236/ijcns.2014.76019

The growing ubiquity of Wi-Fi networks combined with the integration of low-cost Wi-Fi chipsets in all devices makes Wi-Fi as the wireless technology the most used for accessing to internet [1]. This means that the development of a Wi-Fi strategy has become an imperative for almost all operators worldwide. In this context, APs (Access Points) have to become as secure as cellular networks. Furthermore, authentication process between a mobile device and an access point has to be automated, without user constraining configuration. For reaching this purpose, client must have different credentials depending on authentication method. Our goal is to create an architecture that is both ergonomic and flexible in order to meet the need for connection and client mobility. We use NFC technology as a radio channel for starting communication with the network. The communication initiation will instantiate a virtual Wi-Fi AP and distribute all policies and access certificates for an authentication based on EAP-TLS (it could be extended to any EAP method for 802.1X standard). The end result of our new topology is to allow access to services through a virtual Wi-Fi AP with an enterprise-grade in a public hotspot.

Branson's Q-curvature in Riemannian and Spin Geometry
Oussama Hijazi,Simon Raulot
Symmetry, Integrability and Geometry : Methods and Applications , 2007,
Abstract: On a closed 4-dimensional Riemannian manifold, we give a lower bound for the square of the first eigenvalue of the Yamabe operator in terms of the total Branson's $Q$-curvature. As a consequence, if the manifold is spin, we relate the first eigenvalue of the Dirac operator to the total Branson's $Q$-curvature. On a closed $n$-dimensional manifold, $n ge 5$, we compare the three basic conformally covariant operators: the Branson-Paneitz, the Yamabe and the Dirac operator (if the manifold is spin) through their first eigenvalues. Equality cases are also characterized.
Typical Set Cognitive Sensing
Oussama Souihli,Tomoaki Ohtsuki
ISRN Communications and Networking , 2011, DOI: 10.5402/2011/709091
NeuroMap: A Spline-Based Interactive Open-Source Software for Spatiotemporal Mapping of 2D and 3D MEA Data
Oussama Abdoun,Blaise Yvert
Frontiers in Neuroinformatics , 2011, DOI: 10.3389/fninf.2010.00119
Abstract: A major characteristic of neural networks is the complexity of their organization at various spatial scales, from microscopic local circuits to macroscopic brain-scale areas. Understanding how neural information is processed thus entails the ability to study them at multiple scales simultaneously. This is made possible using microelectrodes array (MEA) technology. Indeed, high-density MEAs provide large-scale coverage (several square millimeters) of whole neural structures combined with microscopic resolution (about 50 μm) of unit activity. Yet, current options for spatiotemporal representation of MEA-collected data remain limited. Here we present NeuroMap, a new interactive Matlab-based software for spatiotemporal mapping of MEA data. NeuroMap uses thin plate spline interpolation, which provides several assets with respect to conventional mapping methods used currently. First, any MEA design can be considered, including 2D or 3D, regular or irregular, arrangements of electrodes. Second, spline interpolation allows the estimation of activity across the tissue with local extrema not necessarily at recording sites. Finally, this interpolation approach provides a straightforward analytical estimation of the spatial Laplacian for better current sources localization. In this software, coregistration of 2D MEA data on the anatomy of the neural tissue is made possible by fine matching of anatomical data with electrode positions using rigid-deformation-based correction of anatomical pictures. Overall, NeuroMap provides substantial material for detailed spatiotemporal analysis of MEA data. The package is distributed under GNU General Public License and available at http://sites.google.com/site/neuromapsoftware.
Branson's Q-curvature in Riemannian and Spin Geometry
Oussama Hijazi,Simon Raulot
Mathematics , 2007,
Abstract: On a closed 4-dimensional Riemannian manifold, we give a lower bound for the square of the first eigenvalue of the Yamabe operator in terms of the total Branson's Q-curvature. As a consequence, if the manifold is spin, we relate the first eigenvalue of the Dirac operator to the total Branson's Q-curvature. On a closed n-dimensional manifold, $n\ge 5$, we compare the three basic conformally covariant operators : the Branson-Paneitz, the Yamabe and the Dirac operator (if the manifold is spin) through their first eigenvalues. Equality cases are also characterized.
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