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Search Results: 1 - 10 of 621291 matches for " Oscar de Jesús Pérez Ramírez "
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Valor pronóstico del inmunofenotipo en la respuesta temprana de la leucemia aguda linfoblástica pre-B en ni?os
Correa-González, Lourdes Cecilia;Mandeville, Peter B;Manrique-Due?as, Javier;Alejo-González, Francisco;Salazar-Martínez, Abel;Pérez-Ramírez, Oscar de Jesús;Hernández-Sierra, Juan Francisco;
Gaceta médica de México , 2005,
Abstract: objective: to determine the prognostic value of pre b immunophenotype and its variants on early treatment response among of acute pediatric lymphoblast leukemia. patients and methods: a case control study nested in a cohort was carried out with male and female patients 15 years and younger with recently diagnosed pre b lymphoblast leukemia. a panel of b, t, monoclonal antibodies of the myelo monocytic and megakaryocytic cell type was used. response was assessed by bone marrow aspiration 14 days post treatment. results: 54 patients were included. the median age was 7 years (2 months - 14 years) median leukocyte count was 13,450/mm3 (1200-986,000/mm3). we identified 29 cases with late pre b immune phenotype, 19 cases with common pre b and 6 cases with early pre b immunophenotype. eleven patients also displayed myeloid antigens. a significant association (p=0.034) was found between early treatment response and the presence of myeloid antigens. no association was found between the pre b immunophenotype, age and leukocyte count with early treatment response (p=0.264). conclusions: we need to pay special emphasis on early treatment response in children with lymphoblast leukemia as our study did not corroborate the common finding that clinical factors and immune phenotype can be predictive factors.
Mexican Guidelines for the Diagnosis and Treatment of Chronic Myeloid Leukaemia  [PDF]
Eduardo Cervera, Federico Godínez, Rosa Sosa, Ramón Rivas, Carlos Best, Juan Hernández, Adrián Morales, Hugo Zurita, Ivette Carrasco, Jorge Cruz, álvaro Aguayo, José Espinoza, Juan Labardini, Luis Valero, Judith Cruz, Diana Arcos, Diego Limón, Omar López-Navarro, Daniela Gordillo-Bastidas, Myrna Candelaria, Francisco Torres, Juan Kassack, Oscar de Jesús Pérez Ramírez, Jorge Aquino, Guillermo Díaz, Mariela Cardiel, Margarita Rodríguez, Patricia Montoya, Juan Contreras, María Chávez, Sandra Chávez, David Gómez, Olga Cantú, Jorge Duque, Luis Pita, Eduardo Lobato, Julio López, Antonio López, Pedro González, Jorge Cortés
Journal of Cancer Therapy (JCT) , 2013, DOI: 10.4236/jct.2013.43092
Abstract:

Background: This document includes recommendations and guidelines issued by a group of Mexican researchers and specialists gathered in the First National Colloquium for the Diagnosis and Management of Chronic Myeloid Leukaemia (CML) by initiative of Instituto Nacional de Cancerología and with the support of the Leukaemia Department of the MD Anderson Cancer Center. Mexico lacks of updated information taken from its own reality on the diagnosis and treatment of CML and other haematological disorders; besides, there are no national guidelines. Aim: To publish a consensus document with guidelines for the management of CML adjusted to the national environment and overall characteristics. Method: The participants answered a DELPHI questionnaire about the overall aspects of the disease, aiming to target controversial topics, discuss them in the colloquium, and to agree on the best ones. After those meetings, a final document was drawn up. Results: The group presents recommendations for definition, diagnosis, prognosis, monitoring, and treatment of CML in Mexico. Conclusions: Having consensus guidelines for the clinical management of CML in our country will enable the consensual practice of Mexican specialists regarding the clinical approach to CML, as well as optimize the resources which allow the rational planning of the medical care strategies.

Motor Effects of 1,3-Disubstituted 8-Styrylxanthines as A1 and A2 Adenosine-Receptor Antagonists in Rats  [PDF]
Ilhuicamina Daniel Limón-Pérez de León, María del Carmen Parra-Cid, Alejandro Mu?oz-Zurita, Saúl Alejandro Merino-Contreras, Sara Montiel-Smith, Socorro Meza-Reyes, Gerardo Ramírez-Mejía, Jesús Sandoval-Ramírez
Pharmacology & Pharmacy (PP) , 2013, DOI: 10.4236/pp.2013.43044
Abstract:

A series of 1,3-substituted 8-styrylxanthines (11a-d) was synthesized, under chemo- and regioselective conditions, in a good overall yield. The compounds showed affinity towards both A1 and A2A-adenosine receptors by radioligand binding by means of in vitro assays. The (E)-3-ethyl-1-propyl-8-styrylxanthine (11a) showed the greatest affinity towards the A2A receptor, whereas (E)-3-pentyl-1-propyl-8-styrylxanthine (11d) showed the greatest affinity for the A1 receptor. When the 8-styrylxanthines 11a (A15Et) and 11c (A15Bu) were administrated in rats, which were previously injured with 6-hydroxydopamine at the substantia nigra pars compacta (SNc), the turning behavior decreased 50%. Based on these results we propose to A15Et as a potential compound to treat some symptoms of Parkinson’s disease.

Efecto de la (E)-3-butil-8-estiri1-1-propilxantina sobre la asimetría motora en rata
Alejandro Mu?oz Zurita,Jesús Sandoval Ramírez,Carmen Parra Cid,Daniel Limón Pérez de León
Revista de la Sociedad Química de México , 2002,
Abstract: Se describe la síntesis de la (E)-3-butil-8-estiri1-1-propilxantina (A15Bu) a partir de 6-aminouracilo (6) y un estudio biológico con el modelo experimental antiparkinsoniano de conducta de giro, en ratas de cepa Wistar. Al administrar el compuesto A15Bu en ratas lesionadas con 6-hidroxidopamina (6-OHDA) en la sustancia nigra pars compacta la asimetría motora se redujo en un 75 %.
Valoración económica de los servicios ambientales hidrológicos en El Salto, Pueblo Nuevo, Durango
Silva-Flores, Ramón;Pérez-Verdín, Gustavo;Návar-Cháidez, José de Jesús;
Madera y bosques , 2010,
Abstract: this research explored willingness to pay (wtp) and willingness to accept (wta) payment for conserving water supplies in el salto, pueblo nuevo, durango. personal interviews were applied to both el salto water users to estimate wtp and land resource owners to estimate wta. production costs were estimated at the watershed "la rosilla" near el salto. the production costs included storage, protection, restoration and water supply to el salto residents. in addition, production of water was estimated using a mass balance approach. the results showed that the watershed produces on the average 2,10 mm3/year. about 90% of the water users surveyed in the study were willing to pay for the environmental hydrological service an average of $17,18 for month. likewise, resource owners were willing to accept about $320,00 for month ($5,26/ha/year) as a compensation to forgo forest harvest and stimulate water production. differences between wtp and wta coincide with many other studies that indicate wta is larger than wtp. average production cost was estimated at $2,49/m3 of water for the first year and $2,09/m3 for the remaining years over a 10-year planning period. the cumulative wtp, based on the number of households of el salto, would not be enough to pay for all production costs. other external programs such as carbon sequestration and government subsidies, etc., are necessary to reduce the gap between estimated wtp and production costs.
Biocontrol de la pudrición de raíz de nochebuena de interior con Trichoderma spp. Root rot biocontrol for indoor poinsettia with Trichoderma spp.
Felipe de Jesús Osuna-Canizalez,María Félix Moreno-López,Faustino García-Pérez,Sergio Ramírez-Rojas
Revista mexicana de ciencias agrícolas , 2012,
Abstract: En Morelos, la pudrición de la raíz causada por Fusarium spp., es una de las principales enfermedades de la nochebuena de interior. Por su efecto devastador, en su prevención o control se realizan aplicaciones frecuentes de productos químicos, con los riesgos inherentes a la salud humana y al ambiente. En la búsqueda de alternativas bioracionales al manejo de esta enfermedad, se realizó un ensayo en el que se evaluaron tres cepas comerciales de Trichoderma spp., en tres diferentes sustratos: S1= "tierra de hoja" (70% v/v)+tezontle grueso (15% v/v)+tezontle fino (10% v/v)+agrolita (5% v/v); S2= turba (80% v/v)+ fibra de coco (20% v/v); S3= "tierra de hoja" (70%) + "tepojal" (30%), en las variedades comerciales más comunes, Freedom Red y Prestige Red. Se utilizó un dise o factorial de tratamientos 4 x 3 x 2 y los tratamientos resultantes se evaluaron en un dise o completamente al azar con seis repeticiones. Respecto a la incidencia de pudrición de la raíz, las cepas comerciales de Trichoderma spp., no mostraron diferencias entre sí ni con el testigo químico. La pudrición de la raíz estuvo asociada con S2, debido a una baja capacidad de aireación, y sólo se presentó en Prestige Red. La población (UFC g-1) de Trichoderma spp., en el sustrato al término del ciclo, fue igual (p< 0.05) entre cepas comerciales y entre estas y el testigo químico (sin inoculación), debido a la presencia de cepas nativas de Trichoderma en los componentes orgánicos de los sustratos ("tierra de hoja", turba y fibra de coco). In Morelos, root rot caused by Fusarium spp., is one of the main diseases of indoor poinsettia. In order to prevent or control its devastating effect, frequent applications of chemical products are performed, with inherent risks to human health and environment. In quest for alternative biorational options, an essay in which three commercial strains of Trichoderma spp., was done, in three different substrates: S1= "organic soil" (70% v/v)+thick tezontle (15% v/v)+thin tezontle (10% v/v)+agrolita (5% v/v); S2= peat moss (80% v/v)+ coconut fiber (20% v/v); S3= "organic soil" (70%)+"tepojal" (30%), in most common commercial varieties, Freedom Red and Prestige Red. A factorial design of 4 x 3 x 2 treatment was used and resulting treatments were evaluated in a completely random design with six repetitions. Regards root rot incidence, commercial strains of Trichoderma spp., did not show differences between them, either with chemical control. Root rot was associated with S2, due low aeration capacity, and only it was seen in Prestige Red. Population of Trichoderma spp.,
Self and Foreign Substances in Organic and Conventional Milk Produced in the Eastern Region of Mexico  [PDF]
Rey Gutiérrez, P. Rosell, S. Vega, Jesús Pérez, Acacia Ramírez, Marta Coronado
Food and Nutrition Sciences (FNS) , 2013, DOI: 10.4236/fns.2013.45076
Abstract:

The objective of the present study was to evaluate the physicochemical properties, presence of water and aflatoxin M1, as well as the effect of the time of year (dry or rainy season) to value the quality and safety of conventional and organic raw milk samples. Samples were collected of conventional (n = 12) and organic (n = 11) raw milk from Tizayuca, Hidalgo and from Tuxpan, Veracruz, respectively. Infrared spectrophotometry and other analytical techniques were employed, approved by the International Dairy Federation for the analysis of the physicochemical properties, the cryoscopy technique for the detection of water addition, and high performance liquid chromatography for the determination of aflatoxin M1. Results showed that there are no significant differences in the components of conventional milk in the season of the year, whereas in organic milk a significant difference (P < 0.05) was observed in acidity during the seasons of the year (rainy and dry), as well as a decrease in the percentage of lactose in the dry season, with a significant difference (P < 0.05). The means of the cryoscopic point of the milk samples complied with the limits established in the Mexican Official Norm (0.530,

Morbidity Due to Obesity, Hypertension and Diabetes II Attributable to Non-Breastfeeding and Low Birth Weight during the 1000 Days of Life: Estimation of the Population Attributable Fraction  [PDF]
Andrea Ramírez, Oscar Bernal, Jesús Rodríguez, José David Pinzón
Health (Health) , 2016, DOI: 10.4236/health.2016.85041
Abstract: Introduction: There is evidence that malnutrition during the first 1000 days of life contributes to the development of chronic diseases in adulthood and therefore may produce a lasting impact on the health of the population. Colombia, like other middle-income countries suffers the double burden of malnutrition in pregnant women and children under 5 years. Also, chronic diseases have positioned within the leading causes of morbidity and mortality. Objective: The aim is to estimate the burden of disease of noncommunicable chronic diseases-NCD’s (hypertension, obesity, diabetes mellitus II) in adults attributable to nutritional risk factors (no-breastfeeding and low birthweight) in the period of 1000 days in Colombia. Methods: The population attributable fraction and the number of NCD’s (hypertension, diabetes mellitus II and obesity) cases due to the risk factors (low birthweight and no-breastfeeding) were estimated. Prevalences of NCD’s and risk factors of interest were taken from national health surveys. Effect measures (odds ratios/relative risks) of the associations 1—low birthweight and hypertension, diabetes mellitus II and 2—no-breastfeeding and obesity were obtained after a systematic literature search. Results: It was estimated that not receiving breastfeeding in the 1000 days could contribute up to 29.9% of all cases of obesity, equivalent to about 4,009,779 cases across the country. Low birth weight could contribute up to 2.1% of cases of hypertension in men and to 4.0% of cases in women, equivalent to 103.769 cases across the country. In addition, low birth weight could contribute to 6.3% of diabetes mellitus II cases, which is equivalent to 23.857 cases in the country. Conclusion: In Colombia, risk factors during the first 1000 days like not receiving breastfeeding and having low birth weight could contribute up to 4,113,549 cases of obesity, hypertension and diabetes mellitus II, with important implications for the health of the population and the Colombian health system.
Pérdida del primer molar permanente en ni?os de 7 a 13 a?os
Pupo Arias,Deinys; Batista Zaldívar,Xiomara Bárbara; Nápoles González,Isidro de Jesús; Rivero Pérez,Oscar;
Revista Archivo M??dico de Camag??ey , 2008,
Abstract: background: dental caries is a transmissible, infectious, chronic and multifactorial disease; prevails in the infancy and constitutes the fundamental cause of the dental loss. objective: to determine the loss of the first permanent molar tooth in children from 7 to 13 years. method: an observational, descriptive, longitudinal and prospective study was conducted in 63 children from 7 to 13 years belonging to the sector 1 of the urbanization ?las margaritas?, carirubana municipality, falcón state, from september 2005 to may 2006. the studied variables were: age, sex, damage caused to the oral structures and oral hygiene of the boy. results: of the total of patients, 16 correspond to the male sex, what represented the 57.4% of the sample and 12 patients to the female one for a 42.6%. relating to the age a greater number of patients between 10-11 years with a total of six children was obtained (21,4%). the tooth with greater index of absence was the first right lower molar with a total of 16 for the 37.2%. of the most common oral affections caused by the loss of the first permanent molar tooth, was found that 17 children presented extrusion of the antagonist and 13 unilateral mastication. on analyzing the hygiene in the studied children was observed that just in 11 patients (39,2%) was acceptable and in the 60.8% (17 of the patients) were evaluated as no acceptable. conclusions: the male sex was the most affected one by the loss of the first permanent molar tooth and mostly oral hygiene was no acceptable.
Nefroureterectomía laparoscópica: nueva posición para el manejo ureteral
Aguilera Bazán,Alfredo; Alonso y Gregorio,Sergio; Pérez Utrilla,Manuel; Cansino Alcaide,Ramón; Cisneros Ledo,Jesús; Pe?a,Javier de la;
Archivos Espa?oles de Urología (Ed. impresa) , 2007, DOI: 10.4321/S0004-06142007000600009
Abstract: objectives: the main challenge of laparoscopic nephroureterectomy is the management of distal ureter, which also will have an important repercussion in the oncological outcome of many cases. we present our experience in such aspect, considering that we performed the last five laparoscopic nephroureterectomies in forced trendelemburg position, resulting in a more comfortable and safe management of the distal ureter. methods: between august and december 2006 we performed five purely laparoscopic nephroureterectomies with bladder cuff positioning the patient in forced trendelemburg, a position similar to that of laparoscopic radical cystectomy or prostatectomy. results: mean surgical time was 182 minutes (170-210). mean blood loss was 100 cc and no patient required transfusion. mean hospital stay was four days. conclusions: we believe this position is a good alternative for the management of the distal ureter during the laparoscopic approach. the technique is very similar to open surgery, which continues being the gold standard today.
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