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Search Results: 1 - 10 of 4337 matches for " Omar Akhouayri "
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Does Argan Oil Supplementation Affect Metabolic Parameters and Behavior in Wistar Rats?  [PDF]
Rim Bousalham, Laila Jahidi Rhazali, Amal Harmouch, Hamid Lotfi, Bouchra Benazzouz, Aboubaker El Hessni, Ali Ouichou, Omar Akhouayri, Abdelhalem Mesfioui
Food and Nutrition Sciences (FNS) , 2015, DOI: 10.4236/fns.2015.69085
Abstract: Argan oil is renowned for its particular biochemical profile: high-fat oleic and linoleic acids, tocopherols, sterols, polyphenols. This composition gives it nutritional, therapeutic and preventive properties against dermatological, metabolic and proliferative diseases. The composition of argan oil assigns its benefits to mental health; it would be provided with possible effects on the prevention and/or cure of stress related disorder. This work aims to evaluate the impact of argan oil dietary on the behavioral response, biochemical and hematological constants and histological profiles of adrenal involved in emotional responses to stress. The variation of these parameters was evaluated in Wistar rats receiving dietary 10 ml/Kg/day of argan oil, starting from weaning, for 13 weeks. Our results show that supplementation has resulted in an increase in locomotor activity, reduced sensitivity to frightening environments with sex dependent variation. Moreover, lipid markers, corticosterone and lymphocytes show a rising trend. If the important role of argan oil diet in cardio-metabolic health is generally well recognized; for mental health, it is the first study that needs further investigation linking between the nervous system, inflammation parameters and metabolism.
Toll-8/Tollo Negatively Regulates Antimicrobial Response in the Drosophila Respiratory Epithelium
Idir Akhouayri,Claire Turc,Julien Royet ,Bernard Charroux
PLOS Pathogens , 2011, DOI: 10.1371/journal.ppat.1002319
Abstract: Barrier epithelia that are persistently exposed to microbes have evolved potent immune tools to eliminate such pathogens. If mechanisms that control Drosophila systemic responses are well-characterized, the epithelial immune responses remain poorly understood. Here, we performed a genetic dissection of the cascades activated during the immune response of the Drosophila airway epithelium i.e. trachea. We present evidence that bacteria induced-antimicrobial peptide (AMP) production in the trachea is controlled by two signalling cascades. AMP gene transcription is activated by the inducible IMD pathway that acts non-cell autonomously in trachea. This IMD-dependent AMP activation is antagonized by a constitutively active signalling module involving the receptor Toll-8/Tollo, the ligand Sp?tzle2/DNT1 and Ect-4, the Drosophila ortholog of the human Sterile alpha and HEAT/ARMadillo motif (SARM). Our data show that, in addition to Toll-1 whose function is essential during the systemic immune response, Drosophila relies on another Toll family member to control the immune response in the respiratory epithelium.
Melanotic Pathology and Vertical Transmission of the Gut Commensal Elizabethkingia meningoseptica in the Major Malaria Vector Anopheles gambiae
Idir G. Akhouayri, Tibebu Habtewold, Georges K. Christophides
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0077619
Abstract: Background The resident gut flora is known to have significant impacts on the life history of the host organism. Endosymbiotic bacterial species in the Anopheles mosquito gut are potent modulators of sexual development of the malaria parasite, Plasmodium, and thus proposed as potential control agents of malaria transmission. Results Here we report a melanotic pathology in the major African malaria vector Anopheles gambiae, caused by the dominant mosquito endosymbiont Elizabethkingia meningoseptica. Transfer of melanised tissues into the haemolymph of healthy adult mosquitoes or direct haemolymph inoculation with isolated E. meningoseptica bacteria were the only means for transmission and de novo formation of melanotic lesions, specifically in the fat body tissues of recipient individuals. We show that E. meningoseptica can be vertically transmitted from eggs to larvae and that E. meningoseptica-mono-associated mosquitoes display significant mortality, which is further enhanced upon Plasmodium infection, suggesting a synergistic impact of E. meningoseptica and Plasmodium on mosquito survival. Conclusion The high pathogenicity and permanent association of E. meningoseptica with An. Gambiae through vertical transmission constitute attractive characteristics towards the potential design of novel mosquito/malaria biocontrol strategies.
Hard Decision-Based PWM for MIMO-OFDM Radar  [PDF]
Omar Daoud
Communications and Network (CN) , 2015, DOI: 10.4236/cn.2015.71004
Abstract: For the purpose of target localization, Multiple Input Multiple Output-Orthogonal Frequency Division Multiplexing (MIMO-OFDM) radar has been proposed. OFDM technique has been adopted in order to a simultaneous transmission and reception of a set of multiple narrowband orthogonal signals at orthogonal frequencies. Although multi-carrier systems such as OFDM support high data rate applications, they do not only require linear amplification but also they complicate the power amplifiers design and increase power consumption. This is because of high peak-to-average power ratio (PAPR). In this work, a new proposition has been made based on the Pulse Width Modulation (PWM) to enhance the MIMO-OFDM radar systems’ performance. In order to check the proposed systems performance and its validity, a numerical analysis and a MATLAB simulation have been conducted. Nevertheless of the system characteristics and under same bandwidth occupancy and system’s specifications, the simulation results show that this work can reduce the PAPR values clearly and show capable results over the ones in the literature.
Numerical Investigation of Phase and Group Propagation of Time-Domain Signals in a Novel Band-Reject Metamaterial Ring Hybrid  [PDF]
Omar Siddiqui
Journal of Computer and Communications (JCC) , 2015, DOI: 10.4236/jcc.2015.36002
Abstract: Phase and group propagation in metamaterial-based microwave components has always been intellectually challenging for students and engineers new to the area of periodic structures and metamaterials. This paper aims in tackling this important topic by studying the wave propagation in a metamaterial-based microwave device. Hence, the contribution of this paper is twofold. First, design of a novel metamaterial ring hybrid (or rate-race) is presented which has a large rejection band so that the second and third harmonics are effectively suppressed. Second, the electromagnetic phase and the group propagation in the ring hybrid are investigated by numerically exciting the input ports with band-limited Gaussian pulses and then finding their responses at various locations in the device.
Investigation of the Quaternion Dynamical System  [PDF]
Yasmin Omar
Journal of Applied Mathematics and Physics (JAMP) , 2017, DOI: 10.4236/jamp.2017.51014
Abstract: The quaternion Mandelbrot set is one of the most important sets in mathematics. In this paper we first give some properties of the quaternion algebra. Then, we introduce the quternion dynamical system. We are concerned with analytical and numerical investigation of the quaternion dynamical system.
Pattern-Oriented Approach for Enterprise Architecture: TOGAF Framework  [PDF]
Mohamed Taleb, Omar Cherkaoui
Journal of Software Engineering and Applications (JSEA) , 2012, DOI: 10.4236/jsea.2012.51008
Abstract: Design pattern suggests that developers must be able to reuse proven solutions emerging from the best design practices to solve common design problems while composing patterns to create reusable designs that can be mapped to different types of enterprise frameworks and architectures such as The Open Group Architecture Framework (TOGAF). Without this, business analysts, designers and developers are not properly applying design solutions or take full benefit of the power of patterns as reuse blocks, resulting in poor performance, poor scalability, and poor usability. Furthermore, these professionals may “reinvent the wheel” when attempting to implement the same design for different types of architectures of TOGAF framework. In this paper, we introduce different categories of design patterns as a vehicle for capturing and reusing good analyses, designs and implementation applied to TOGAF framework while detailing a motivating exemplar on how design patterns can be composed to create generic types of architectures of TOGAF framework. Then, we discuss why patterns are a suitable for developing and documenting various architectures including enterprise architectures as TOGAF.
Exploring QSARs for Inhibitory Activity of Cyclic Urea and Nonpeptide-Cyclic Cyanoguanidine Derivatives HIV-1 Protease Inhibitors by Artificial Neural Network  [PDF]
Omar Deeb, Mohammad Jawabreh
Advances in Chemical Engineering and Science (ACES) , 2012, DOI: 10.4236/aces.2012.21010
Abstract: Quantitative structure–activity relationship study using artificial neural network (ANN) methodology were conducted to predict the inhibition constants of 127 symmetrical and unsymmetrical cyclic urea and cyclic cyanoguanidine derivatives containing different substituent groups such as: benzyl, isopropyl, 4-hydroxybenzyl, ketone, oxime, pyrazole, imidazole, triazole and having anti-HIV-1 protease activities. The results obtained by artificial neural network give advanced regression models with good prediction ability. The two optimal artificial neural network models obtained have coefficients of determination of 0.746 and 0.756. The lowest prediction’s root mean square error obtained is 0.607. Artificial neural networks provide improved models for heterogeneous data sets without splitting them into families. Both the external and cross-validation methods are used to validate the performances of the resulting models. Randomization test is employed to check the suitability of the models.
A Space Unrestricted Multi-Robot Combat Internet of Things System  [PDF]
Omar Said, Mehedi Masud
Advances in Internet of Things (AIT) , 2012, DOI: 10.4236/ait.2012.23007
Abstract: Multi-robot cooperation problem has received increasing attention in the research community and has been extensively studied from different aspects. Space constrain problem is a major issue for building a multi-robot system. This con- strain is a major hindrance for the efficient cooperation among robots in multi-robot applications. In this paper, we demonstrate a novel architecture of a multi-robot system without space restriction. Our architecture is based on the Internet of Things technology. We validated the proposed architecture using a case study considering a multi-robot combat application.
The Appearance of Noise Terms in Modified Adomian Decomposition Method for Quadratic Integral Equations  [PDF]
Huda Omar Bakodah
American Journal of Computational Mathematics (AJCM) , 2012, DOI: 10.4236/ajcm.2012.22017
Abstract: In this paper, we apply the modified Adomian Decomposition Method to get the numerical solutions of Quadratic integral equations. The appearance of noise terms in Decomposition Method was investigated. The method was described along with several examples.
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