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Search Results: 1 - 10 of 1310 matches for " Olusoji Abidemi Solomon "
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Pattern of Upper Gastrointestinal Malignancies as Seen at Endoscopy in Ekiti State University Teaching Hospital, Ado-Ekiti, Nigeria  [PDF]
Akande Oladimeji Ajayi, Ebenezer Adekunle Ajayi, Olusoji Abidemi Solomon, Emmanuel Abidemi Omonisi, Samuel Ayokunle Dada
Open Access Library Journal (OALib Journal) , 2016, DOI: 10.4236/oalib.1102731
Abstract:
Aims and Objective: Gastrointestinal malignancies are among the most lethal of all malignancies and are equally notorious for rapidly progressing to advanced stages even in the absence of serious symptoms, thus leading to delayed diagnoses and dismal prognoses. The aim of this study was to determine the prevalence, type, pattern and the histologic characteristics of upper gastrointestinal tumors seen in patients who underwent upper gastrointestinal endoscopy at the Ekiti State University Teaching Hospital, Ado-Ekiti, Nigeria. Materials and Methods: This was a three year cross-sectional study involving 78 patients with suspected upper gastrointestinal tumor referred for upper gastrointestinal endoscopy. The study was conducted from January 2011 to December 2013 at the Ekiti State University Teaching Hospital (EKSUTH), Ado-Ekiti, Nigeria. Relevant clinical information such as age, gender, clinical presentations, smoking history, alcohol use, spices, and consumption of opiates were obtained from the patients. Tissue biopsies were taken from the suspected lesions for histological confirmation and characterization. An ethical clearance for this study was obtained from the EKSUTH Ethical and Research committee and all the patients gave written consent for the study. SPSS version 15.0 (SPSS, Inc., Chicago, Illinois, USA) was applied for statistical analysis using the t-test for quantitative variables and χ2 test for qualitative variables. Differences were considered to be statistically significant if P value was less than 0.05. Results: Seventy eight patients were enrolled into this study comprising 22 females and 56 males. The mean age of the population was 55.75 ± 7.20 years. The presenting symptoms were; abdominal mass in 30.8%, abdominal pain in 29.5%, weight loss in 20.5%, dysphagia in 6.4%, haematemesis in 5.1%, melaena in 5.1% and anaemia in 2.6% of the patients. The risk factors identified in the study included; tobacco use or smoking in 25.6%, alcohol in 19.2%, spices in 14.1%, opiates in 3.8% and combination of the above risk factors in 37.2%. 67.9% of the tumors were located in the stomach, 16.7% in the oesophagus and 15.4% in the first part of the duodenum. Of those located in the stomach, 62.3% were in the antrum while 37.7% were in the corpus. Of the oesophageal tumors, 61.5% were in the mid oesophagus, 30.8% were in the lower oesophagus and 7.8% in the upper oesophagus. Tissue histology showed 70.5% were adenocarcinoma, 26.9% were squamous cell carcinoma, 1.3% lymphoma and 1.3% malignant polyp. This was statistically significant p =< 0.05. Conclusion: In view of the fact that upper GI tumors can rapidly progress to advanced stages in the absence of serious symptoms, gastroduodenoscopy is advocated in patients with signs and symptoms of dyspepsia to avoid delayed diagnosis and improve the disease outcome.
Smoking Impact on the Microbial Load of Clarias gariepinus
OA Abidemi-Iromini, OO Olawusi-Peters, A Fadeyi, OA Bello-Olusoji
Ethiopian Journal of Environmental Studies and Management , 2011,
Abstract: Effects of different smoking methods on microbial load on freshly collected freshwater mud fish, Clarias gariepinus samples from Oyo State Fisheries Department, Ibadan in South-Western Nigeria was carried out. Seventy-two C. gariepinus (505 ± 0.45g and 25.5 ± 1.30cm) were collected and sorted into 4 groups. 10 fish samples from groups 1, 2 and 3 were subjected to cold smoking, hot smoking and oven drying methods respectively using group 4 as standard. Samples were tested for microbial loads in triplicate at the end of 24, 48 and 72 hrs. Some of the microbes identified were; Streptococcus faecium, Proteus vulgaricus, Pseudomonas aureginiosa, Bacillus cereus; Micrococcus acidiophilus, Aerobacter aerogenes, E. Coli, Streptococcus pyrogenes, Streptococcus lactis, Bacillus subtilis, Pedio cerevisiae, Sacchomyces Sp, Fusarium oxysporum, F. compacticum, Penicillium oxalicum, P. chrysogenum, Aspergillus tamari, A. niger, Cladosporum sphacrosporum, Aspergillus terreus and Rhizopus nigericans. Others are Pseadomonas, Alteromonas, Moraxella, Acinetobacter, Flavobacterium, Cytophaga, Vibrio, Aeromonoas, Staphylococcus aureus, Samonella faecuim, P. fragii. Microbial load for cold smoked products were 72%, 66% and 38%; hot smoked products had 61%, 32% and 08%; while oven-dried had 12%, 0% and 0% at 24, 48 and 12 hrs respectively. Positive correlation r = 0.94, 0.92 and 0.51 were observed between the microbial load processing methods – oven dried, hot-smoked and cold-smoked respectively. Cold smoked had 41.63% C.P and oven-dried had 25.73% C.P. Consumers had highest preference (40%) for hot smoked, 35% for oven dried and 25% for cold smoked products. Key Words: Processing, storage, smoking, bacteria, Clarias gariepinus.
Levels of Pb, Fe, Cd and Co in Soils of Automobile Workshop in Osun State, Nigeria
OO Abidemi
Journal of Applied Sciences and Environmental Management , 2011,
Abstract: The disposal of waste of all kinds in auto-repair workshop areas in Nigeria is becoming alarming. The study looks into the contribution of different sections in auto-repair workshop to heavy metal pollution in soil .Thirty –two soil samples were collected at an auto-repair workshop in Osogbo, Ikirun, Iragbiji and Iree in Osun State for their cobalt, iron , lead and cadmium level at different sections namely: auto-mechanic unit, auto welding unit, auto electrician unit and auto painting unit using atomic absorption spectrophotometer.The highest cobalt concentration was obtained in Iree at the auto welding unit, (17.25± 1.10mg/kg), iron had its highest level in Ikirun at the auto-mechanic unit (43937± 35mg/kg) , lead had its highest concentration in Iree at the auto welding unit (2460±16 mg/kg) and cadmium with the highest in Iree at the auto welding unit as well (2.02 ±1.01 mg/kg).Sites studied had higher levels of heavy metals compared to control areas. The general trend of dispersion of metal contamination within the soil profile is iron>> lead>> cobalt>cadmium. Statistical analysis reveals correlation between lead/iron (r = 0.636) at p<0.01. This work reveals the individual contribution of various allied artisans to soil pollution in automobile workshop. The research serves as an important contribution to the database on the baseline qualities of Nigerian soil.
Spectrum of congenital heart diseases in an African population: A necropsy study  [PDF]
MO Thomas, Olugbenga Olusoji, Nicholas Awolola
World Journal of Cardiovascular Diseases (WJCD) , 2013, DOI: 10.4236/wjcd.2013.31008
Abstract:

Background: The spectrum and incidence of congenital heart diseases amongst African population are not well defined in literature. There is the need to further elucidate the spectrum and epidemiology of congenital heart diseases amongst African. Aim: This study was conducted to highlight the spectrum and occurrence of congenital heart diseases in an African population. Methodology: All paediatric patients who were autopsied over a 98-month period were checked for occurrence of congenital heart diseases. Attempts were made to ascertain the primary disease and causes of death. We noted their bio-data, ages, sexes and causes of death. The results were analysed with SPSS version 17. The results formed the basis for discussion and recommendations. Results: There were 135 cardiac related deaths and 36 of them were in paediatric age brackets. The mean age was 4.7 + 1.08 months with a standard deviation of 6.27. M:F ratio was 1:1.1. The commonest anomaly was ventricular septal defect. There was a weak association with other congenital anomalies. The commonest cause of death was bronchopneumonia. Discussion and Recommendation: The disease pattern showed reasonable similarity with reports from other parts of the world. However, there is need for development of capacity for prenatal diagnosis of congenital heart diseases in Africa. This will widen the net of diagnosis and improve accuracy of incidence studies in Africa.

The quest for universal access to effective malaria treatment: how can the AMFm contribute?
Lloyd Matowe, Olusoji Adeyi
Malaria Journal , 2010, DOI: 10.1186/1475-2875-9-274
Abstract: Access to medicines frameworks paint a broad picture of dimensions of access to medicines and juxtapose components that enhance or hinder access to medicines. Access requires various activities--funding, institutions, interventions, and thinking--from public and private actors at global, national, and local levels. This paper examines, within access to medicines frameworks, the role of the AMFm across and within each dimension and discusses how the AMFm can help to solve access bottlenecks.Universal access to effective malaria treatment is among the United Nations' Millennium Development Goals [1]. This also is among the goals of the Roll Back Malaria Partnership [2]. In spite of high-level commitments, political will and substantial increases in financing, the attainment of this goal has remained elusive in most malaria-endemic countries [3], especially in relation to artemisinin-based combination therapy (ACT), the treatment recommended as first-line by the World Health Organization (WHO) for uncomplicated malaria caused by Plasmodium falciparum [4].In the World Malaria Report 2009 [3], WHO reported that access to ACT was generally poor in African countries, with less than 15 percent of children under five years of age receiving an ACT when they had fever in 11 of 13 African countries for which survey data were available. These findings are consistent with results of more recent multi-country surveys[5], which included findings for the Democratic Republic of Congo and Nigeria, the largest countries with regard to malaria burden and which together account for approximately 36 percent of all estimated malaria cases in the WHO Africa Region [3].The Affordable Medicines Facility-malaria (AMFm) is a new financing mechanism to expand access to effective malaria treatment [6-8]. A response to the dual challenge of poor access to quality-assured anti-malarial medicines and threats of parasite resistance to treatment [6], the AMFm combines price negotiations with a factory
The Benefits and Dangers of Outsourcing Employees in an Emerging Economy
Damaro Olusoji Arubayi
Acta Universitatis Danubius : Administratio , 2012,
Abstract: This paper presents the findings of the benefits and dangers of outsourcing in an emerging economy using hr managers selected public and private sectors as case studies. The aim of the study was to determine the impact of outsourcing on the employees. The findings suggested that although it has positive outcomes in achievement of organizational goals, employees are weakened by the negative impact of outsourcing as it increases job insecurity, demotivation in the organization. The significance of the study was to highlight the impact of outsourcing on employees and its relation with management although there’s not much empirical evidence, this paper thus addresses this issue. It is hoped that this study would add to knowledge, create awareness, refine the existing practices in the organization and change the attitudes of employees for better performance and organizational success.
Adult Cardiac-Related Deaths: A Reflection of Epidemiologic Transition of Diseases in the Developing World?  [PDF]
Martins Oluwafemi Thomas, Nicholas A. Awolola, Olugbenga O Olusoji
World Journal of Cardiovascular Surgery (WJCS) , 2012, DOI: 10.4236/wjcs.2012.24020
Abstract:

Background: Epidemiologic transition of diseases is taking place globally. Therefore, it is necessary that more work is done to unravel the situation in respect to cardiac diseases in the developing world; Aim: The research was conducted to ascertain the cardiac causes of death in adults and by extension to further unravel the epidemiologic transition in relation to cardiac diseases in the developing world. Materials and Methods: This is an autopsy study of adult cardiac related causes of death in the year 2010 at the Lagos University Teaching Hospital in Nigeria, West Africa. It was conducted based in a 700-bedded hospital that has a catchment area of about 15 million people. Patients’ data (including bio-data, causes of death, etc.) were extracted from autopsy records for the year 2010. The data were entered and analysed with SPSS software. Results: There were 789 autopsies in the year and 99 of deaths were cardiac-related. There was male preponderance with a mean age of 54.2 ± 1.568 years. Hypertensive heart disease was the primary disease in 97.0% of cases in the studied sample. One 76 year old adult had myocardial infarction. There was no case of adult congenital heart disease. Intracerebral haemorrhage was the commonest cause of death. Discussion and Conclusion: Cardiovascular diseases constitute a growing threat to health among Africans. The developing countries are in stages II and III of Omran epidemiologic transition of diseases. This presents a major challenge to a large proportion of the world population with additional problem of poverty and ignorance. A 4-point agenda is suggested to reduce incidence of cardiovascular diseases (and deaths) in the developing world.

Aetiology and Demographic Attributes of Common Pleural Collections in an African Population  [PDF]
Ezekiel O. Ogunleye, Martins O. Thomas, Olugbenga O. Olusoji
Surgical Science (SS) , 2013, DOI: 10.4236/ss.2013.47066
Abstract:

Background: Fluids collect in the pleural space under different conditions and they are of different types. Detailed study of demographic attributes and aetiology of pleural collections has not been well reported in Africa. Aims and Objectives: This study was conducted to determine the demographic attributes and aetiology of common pleural space fluid collections. Methods: The sample population consisted of referrals received via clinics, admission through the emergency centre and wards. We noted their biodata, hospital identification numbers, ages and gender and other relevant parameters. Data analysis was done with special interest in gender-based diseases like ovarian carcinoma prostatic carcinoma and the like. Results: There were 372 patients over a 55-month period. The M:F ratio was 1:1 approximately. The combined mean age was 37.8 ± 0.92 years at 95% confidence interval. Their distribution was negatively skewed and it was leptokurtic. The age bracket of 20 - 49 had 65.6% of cases. There was gender based disparity in ages. Discussion: Malignant effusions constituted majority of sample size and the right side was consistently affected more often than the left side. Conclusion: Advanced malignancies are the commonest causes of pleural effusion. There is ongoing epidemiologic transition of diseases as the burden of non-communicable diseases is now juxtaposed with that of communicable diseases in Africa.

Nutritive Values and Antioxidant Activity of Citrullus lanatus Fruit Extract  [PDF]
Adewale Adetutu, Olubukola Sinbad Olorunnisola, Olusoji Abiodun Owoade
Food and Nutrition Sciences (FNS) , 2015, DOI: 10.4236/fns.2015.611109
Abstract: Citrullus lanatus (Watermelon) is a fruit cultivated and consumed in Africa for its essential nutrients which are very beneficial to the human body. The present study was designed to evaluate the nutritive contents, free radical scavenging activities and phytochemical components of C. lanatus fruit. The extract of the fruit was subjected to in vitro antioxidant assessment using 1,1-di-phenylpicryl-hydrazyl radical (DPPH) and hydrogen peroxide radical scavenging assays. The proximate and phytochemical analyses were conducted using standard procedures. The results of this study showed that C. lanatus fruit had very high moisture content and its crude protein, crude fat, crude fibre and ash content were all in traceable amounts. The sugar content was considerably high in comparison with other nutritive contents. Lycopene and β-carotene contents of C. lanatus fruit were estimated to be 4537.83 and 308.71 μg/100g respectively. The gross energy evaluation showed a value of 0.335 Kcal/g. The fruit extract exhibited significant (p < 0.05) DPPH (IC50 of 0.10 mg/ml) and hydrogen peroxide radicals scavenging activity (IC50 of 0.62 mg/ml) in comparison with the positive control butylated hydroxytoluene (BTH). This study therefore recommends that C. lanatus fruit could be an excellent source of antioxidants which may prevent diseases whose pathogenesis involves oxidative stress.
Influence of Polyphenolic Contents on the Antioxidant Properties of Hibiscus sabdariffa Extract (HSE), Aged Garlic Extract (AGE) and Garlic Tablet (GT) in Vitro  [PDF]
Abiodun Olusoji Owoade, Adewale Adetutu, Olubukola Sinbad Olorunnisola
Food and Nutrition Sciences (FNS) , 2016, DOI: 10.4236/fns.2016.76043
Abstract:
This study compared the antioxidant properties of Hibiscus sabdariffa extract (HSE), commercial aged garlic extract (AGE, Kyolic) and garlic tablet (GT). The results indicate that HSE, AGE and GT are effective antioxidant as xanthine/xanthine oxidase generated superoxide ions are significantly inhibited in the presence of 20% (v/v) diethyl ether extract of HSE, AGE and GT by 100%, 66.39% and 18.61% respectively, while uric acid production is not affected byAGEand GT. However, at 2.5% and 5.0% (v/v) reaction volumes,HSEsignificantly inhibits uric acid production by 9.5% and 33.0% respectively, and this suggests that components ofHSEinhibit xanthine oxidase activity while AGE and GT scavenge superoxide. In addition, it is also found that the three extracts scavenge ABTS radical cations in dose-dependent manner. In all cell free assays, HSE is found to be more effective as an antioxidant when compared with AGE and GT under the same experimental conditions. Chromatographic and colorimetric analyses suggest thatHSEhas numerous different types of phenolic compounds with higher amount of phenolic compounds (14.9 mg/g) when compared withAGE(2.8 mg/g) and GT (3.6 mg/g) catechin equivalent respectively. Therefore, the effectiveness of antioxidant activities of these three extracts may be related to their phenolic content.
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