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Search Results: 1 - 10 of 6025 matches for " Nubia Broetto Cunha "
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Effects of chronic caloric restriction on kidney and heart redox status and antioxidant enzyme activities in Wistar rats
Marcio Ferreira Dutra*, Ivi Juliana Bristot, Cristiane Batassini, Nubia Broetto Cunha, Adriana Fernanda Kuckartz Vizuete, Daniela Fraga de Souza, Jose Cl
BMB Reports , 2012,
Abstract: Caloric restriction (CR) has been associated with healthbenefits and these effects have been attributed, in part, tomodulation of oxidative status by CR; however, data are stillcontroversial. Here, we investigate the effects of seventeenweeks of chronic CR on parameters of oxidative damage/modification of proteins and on antioxidant enzyme activitiesin cardiac and kidney tissues. Our results demonstrate that CRinduced an increase in protein carbonylation in the heartwithout changing the content of sulfhydryl groups or theactivities of superoxide dismutase and catalase (CAT).Moreover, CR caused an increase in CAT activity in kidney,without changing other parameters. Protein carbonylation hasbeen associated with oxidative damage and functionalimpairment; however, we cannot exclude the possibility that,under our conditions, this alteration indicates a differentfunctional meaning in the heart tissue. In addition, wereinforce the idea that CR can increase CAT activity in thekidney.
Estudo das altera??es eletrocardiográficas com o uso de antidepressivos tricíclicos em pacientes com dor cr?nica
Cunha Jr., Ricardo Joaquim da;Barrucand, Louis;Ver?osa, Nubia;
Revista Brasileira de Anestesiologia , 2009, DOI: 10.1590/S0034-70942009000100007
Abstract: background and objectives: tricyclic antidepressants (tcas) are widely used as analgesics in chronic lumbar pain and neuropathic pain. the objective of this study was to evaluate the electrocardiographic changes in patients with chronic pain treated with amitriptyline or imipramine. methods: forty patients, ages 26 to 81 years (57.27 ± 13.65 years) of both genders (female 19, male 21), with neuropathic syndromes (lumbosciatalgia, postlaminectomy syndromes, and post-herpetic neuritis, among others) participated in this study; 60% had cardiovascular diseases; 30% had changes in the ecg (rbbb, lbbb, first-degree avb, lahb, or pvcs). three ecgs were done in each patient: one ecg was done before beginning treatment, and 30 and 60 days after beginning treatment evaluating pr, qrs, qt, qtc, dqt, dqtc, and hr. thirty-two patients were on amitriptyline and eight on imipramine. the mean dose at the end of the study was 54.29 mg of amitriptyline and 46.87 mg of imipramine. results: analysis of electrocardiographic parameters after the use of tcas showed that amitriptyline caused a transitory increase in heart rate in females (p = 0.049), and the duration of the qrs in patients 60 years or older and patients with cardiopathies (p = 0.01). in patients who received 75 mg of amitriptyline, the qtc interval was greater when compared to that of patients who received 25 mg of the drug (p = 0.0044). the increase in those parameters demonstrated the effects of amitriptyline on cardiac conduction; however, clinical compromise was not seen, since they remained within normal limits (qrs < 110 msec and qtc < 470 msec). conclusions: the chronic use of tacs proved to be safe and effective, and it did not show changes in cardiac conduction with clinical repercussion.
Ultra-som terapêutico contínuo térmico em modelo experimental de ciatalgia
Ciena, Adriano Polican;Oliveira, Jaques Jean Junqueira;Cunha, Núbia Broetto;Bertolini, Gladson Ricardo Flor;
Fisioterapia e Pesquisa , 2009, DOI: 10.1590/S1809-29502009000200014
Abstract: therapeutic ultrasound is a physical therapy resource for relieving sciatic pain. the aim of this study was to assess the effectiveness of continuous therapeutic ultrasound in two different power densities (0,5 w/cm2 and 1 w/cm2), on reducing pain in rats submitted to a sciatica experimental model. twenty rats were used, divided into 3 groups: g1 (n=6) submitted to sciatica and placebo treatment; g2 (n=7) submitted to sciatica and treated with 0.5 w/cm2 ultrasound; and g3 (n=7), submitted to sciatica and treated with 1 w/cm2 ultrasound. sciatica was provoked by surgical nerve compression on the right posterior limb of all animals. treatment on the surgical procedure region consisted in ten daily 5-minute sessions, starting on the 3rd postoperative day. pain was inferred by the time of paw elevation (tpe) during gait, measured before the surgery and on five further moments. results showed tpe increase in all groups after surgery; but in both groups actually treated with ultrasound a significant tep decrease was noticed, practically reaching initial values, the decrease being more precocious and intense in g2. continuous ultrasound such as was delivered was hence effective in reducing sciatic pain.
Uso do laser, 670 nm, no quadro álgico de ratos submetidos à modelo experimental de ciatalgia
Cunha, Núbia Broetto;Moesch, Juliana;Mallmann, Juliana Schmatz;Ciena, Adriano Policam;Bertolini, Gladson Ricardo Flor;
Revista Brasileira de Medicina do Esporte , 2008, DOI: 10.1590/S1517-86922008000200006
Abstract: sciatica is caused by the sciatic nerve compression in some point of its course, and its treatment consists of solving the nervous compression cause, either by surgical or conservative treatment. some physiotherapeutic resources act basically in the reduction of the symptoms caused by this disturbance. the aim of this study was to verify the effectiveness of the laser 670 nm, in two different energy densities, in the pain reduction, in rats submitted to a sciatica experimental model. eighteen rats, divided in 3 groups were used: g1 (n=6) submitted to sciatica and simulated treatment (placebo group), g2 (n=6) submitted to sciatica and treated with laser 2 j/cm2, g3 (n=6) submitted to sciatica and irradiated with laser 4 j/cm2. the hamstring nerve of the animals' right hind limb was exposed and compression with catgut thread in 4 points of the nerve was performed. on the 3rd post-operation day, the treatment was begun with laser in the surgical procedure area of the right hind limb for 10 days. the time during which the limb remained on the air was verified through gait in the following periods: previous to the sciatica, before and after treatment. the results have demonstrated that the laser was not effective in the pain reduction; however, with 4 j/cm2 there was positive effect, without complete functionality reestablishment.
Aplica??o do laser 808nm na dor articular cr?nica de ratos Wistar
Bertolini, Gladson Ricardo Flor;Ciena, Adriano Polican;Silva, Taciane Stein da;Junqueira, Jaques Jean Oliveira;Cunha, Núbia Broetto;
Revista Brasileira de Medicina do Esporte , 2009, DOI: 10.1590/S1517-86922009000500006
Abstract: during the inflammatory process some kinds of cells are predominant and are involved with pain production. low power laser seems to be useful in the control of inflammatory mediators, but wide divergence in the dosemetric parameters leads to variations in its positive results. the aim of this study was to assess the use of the 808nm laser in the chronic joint pain and edema of wistar rats submitted to synovitis. sample was composed of 10 wistar rats divided in two groups: cg - synovitis induction on right knee and placebo treatment; tg - synovitis induction and irradiated with 10j/cm2 laser. 100μl of 5% phormaline were injected in the right tibiofemoral joint space. pain assessment occurred by the time of paw elevation (tpe). on the 10th day after synovitis induction, laser treatment began on the knee medial joint surface and this procedure was kept for 10 days. the outcomes showed that laser presented analgesic effects, since significant reduction of the tpe values was observed for the treated group, hence indicating pain reduction when compared with the pre-treatment values; the same situation did not occur to the group which received the placebo treatment. concerning edema, laser has also shown significant reduction. it can be concluded that laser 808nm with 10j/cm2 is efficient in reduction of chronic joint pain and edema in animals submitted to experimental synovitis.
Efeitos do ultrassom terapêutico em modelo experimental de ciatalgia
Ciena, Adriano Policam;Cunha, Núbia Broetto;Moesch, Juliana;Mallmann, Juliana Schmatz;Carvalho, Alberito Rodrigo de;Moura, Paula Jaqueline de;Bertolini, Gladson Ricardo Flor;
Revista Brasileira de Medicina do Esporte , 2009, DOI: 10.1590/S1517-86922009000700004
Abstract: the sciatica possesses great general population prevalence, and its treatment tends to solve the nervous compression causes. physiotherapy aims to reduce the symptoms caused by compression. this study aimed to evaluate the effectiveness of therapeutic ultrasound on pain in animals subjected to sciatica experimental model. eighteen rats were used and they were divided in 3 groups: group sg (n=4) submitted to the sciatica and treated with the ultrasound off, group pug (n=7) submitted to the sciatica and treated with pulsed ultrasound 2 w/cm2 (satp; 0,4 - sata) and group cug (n=7) submitted to the sciatica and treated with continuous ultrasound (0,4 w/cm2). the sciatic nerve of the posterior right limb was exposed to the compression with catgut wire in 4 points. in the 3rd postoperative day, the indirect treatment was started (right inferior limb) for four days. in the 9th postoperative day, the direct treatment begins on the surgical procedure area for 5 serial days. the paw elevation time, during the march, of the animal was verified before and after the sciatica, at the 3rd, 6th, 9th and 13th postoperative day. the results demonstrated that the application of the therapeutic ultrasound reduced the pain with both treatments in pug and cug, and it has tended larger effectiveness in the pulsed form.
Influência do alongamento passivo em três repeti??es de 30 segundos a cada 48 horas em músculo sóleo imobilizado de ratos
Menon, Thiago;Casarolli, Luana Muriel;Cunha, Núbia Broetto;Souza, Leandro de;Andrade, Paulo Henrique Muleta;Albuquerque, Carlos Eduardo de;Bertolini, Gladson Ricardo Flor;
Revista Brasileira de Medicina do Esporte , 2007, DOI: 10.1590/S1517-86922007000600010
Abstract: the skeletal muscle has the property to adapt to different stimuli, alternating the number of sarcomeres in series, according to the length to which it is submitted to. this investigation has the aim to compare weight and length adaptations of the soleus muscle in rats, besides the total estimate of the sarcomeres in series, when submitted to intermittent stretching during immobilization in plantarflexion. twenty-four 14 ± 2 weeks old wistar male rats were used. they were divided in 4 groups, namely: c (n = 6) - control; a (n = 6) - stretched left soleus muscle (lsm); i (n = 6) - immobilized left soleus muscle; ia (n = 6) - immobilized and stretched lsm. the used protocol was of 3 stretching sets with 30 s duration at every 48 h, and total immobilization period of 21 days. the variations observed were compared between right soleus muscle (rsm) and lsm concerning muscular weight, muscular length and estimate of number of sarcomeres in series (enss), through counting in 300 mm. in the analyzed variables, when rsm (control) and lsm were compared (submitted to stretching and/or immobilization) the following were observed: muscular weight: c = -1.59% (p = 0.67); a = +5.41% (p = 0.05); i = -41.48% (p = 0.01); ia = -32.46% (p = 0.01); muscular length: c = -2.63% (p = 0.43); a = +7.54% (p = 0.07); i = -12.74% (p = 0.01); ia = -10.42% (p = 0.11); enss: c = -3.81% (p = 0.09); a = +2.73% (p = 0.56); i = -12.20% (p = 0.01); ia = -12.21% (p = 0.21). it is concluded that stretching during immobilization has preserved muscular length and the amount of sarcomeres in series; however, it did not prevent muscular weight loss.
A influência das economias emergentes em assuntos internacionais
Nieto, Nubia;
Estudos Avan?ados , 2012, DOI: 10.1590/S0103-40142012000200011
Abstract: this article explores the impact of emerging economies in international affairs. the arrival of the bric's countries (brazil, russia, india and china) has changed the map of the global order and the strategies to project hegemonic power. could the bric eclipse the economic power of the richest countries of the world? what are the main strategies of bric to project its power worldwide? these and other questions are analysed in this text taking into account the new geopolitical scenario of the twenty-first century.
La socialización de las élites políticas mexicanas a través de la corrupción
Análisis Político , 2011,
Abstract: this article focuses on the study of corruption as one of the factors influencing and facilitating the socialization of mexican political elites in the context of political relations based on close friendship, family relations, caciquism or bossism, and patronage. it also analyzes the phenomenon of corruption as a factor in the process of political recruitment, mobility of elites and provides a scheme in the exercise of political power in mexico.
Political Corruption and Narcotrafficking in Mexico
Nubia Nieto
Transcience : a Journal of Global Studies , 2012,
Abstract: In recent years Mexico has been the headlines of the news of drug-related violence. The power of the gangs challenges the army and the police, killing and torture political leaders, policemen, soldiers and civilians. They seem to be unbeatable. However, they could not have prospered, without the conditions of the political corruption of the country. This article analyses the development of political corruption and drug trafficking in Mexico. Firstly, it analyzes the role of the corruption during the post-revolutionary political system headed by the Institutional Revolutionary Party (PRI). Secondly, it studies the arrival in power of the technocrats and their relationship with drug traffickers. Then, it evaluates briefly the political transition thought the defeat of the PRI in July 2000 by the National Action Party (PAN). Finally, it examines the flourishing of narcoindustry in Mexico, the militarization, the rise of the violence and its social consequences for the population.
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