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Search Results: 1 - 10 of 341221 matches for " Norah S. Al-Johani "
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Acute Impact of Artificial Sweetener, Aspartame on Blood Parameter in Mice  [PDF]
Ayoub A. Bazzaz, Norah S. Al-Johani
Advances in Bioscience and Biotechnology (ABB) , 2018, DOI: 10.4236/abb.2018.910038
Abstract: Aspartame (APM) or L-aspartyl-L-phenylalanine methyl ester, a common artificial non-saccharide sweetener used as a sugar substitute in many foods and beverages, has shown some side effects on consumers. The objective of the present study is to study the acute impact of various doses of daily ingestion of APM on blood parameters of mice. Sixty healthy 3 months old male mice raised in the departmental animal house were divided into five groups i.e. the control were fed normal diet and tap water, while other 4 groups (12 each) were daily orally fed with 1 mL of either 40, 500, 1000 or 1500 mg/Kg b wt, dissolved in distilled water using gavages for consecutive 5 weeks. Fresh blood samples collected directly from the heart at dissection were subjected to complete blood counting (CBC) using automated blood analyzer (Cell DYN-1700) in addition to manual differential Leucocytes (WBC) counting. There has been a significant increase (p 0.01) in WBC counts starting from the lowest dose (40 mg/Kg·b·wt); significant decrease (p 0.01) in both Hemoglobin percentages (Hb%) and in Lymphocyte percentages (p 0.004) in comparison with control. It is concluded that the ingestion of aspartame using the above doses has acute impact and is not dose-dependent on blood parameters which could exert further, on the long run, health risks on to other tissues of consumers.
Acute Impact of the Artificial Sweetener Aspartame on the Ultrastructures of Hepatocyte in Mice  [PDF]
Norah S. Al-Johani, Ayoub A. Bazzaz
Advances in Bioscience and Biotechnology (ABB) , 2019, DOI: 10.4236/abb.2019.106012
Abstract: A non-saccharide artificial sweetener, aspartame (L-aspartyl-L-phenylalanine methyl ester) is used worldwide as a sugar substitute in many foods and beverages. The objective of this work was to clarify the acute impact of various doses of daily ingestion of Aspartame at the cellular level of the liver tissues in mice. Sixty adult male mice were divided into five groups including control fed normal diet and tap water, while other 4 groups (12 each) were daily fed orally with 1 mL of either 40, 500, 1000 and 1500 mg/Kg b.wt. APM dissolved in distilled water using gavages for consecutive 5 weeks. Liver samples fixed in 10% formalin were cut as 5 μm using Leica microtome and the sections were stained with both routine Heamatoxylene and Eosin (H & E) as well as Transmission electron Microscope (TEM). Histological results showed cellular changes in the hepatic tissues which were proportional with the increased doses. The hepatocytes had developed fatty droplets in the cytoplasm of almost all cells, loss of nuclei, necrosis detectable at LM level. Lymphatic nodules were also generated around the triads and the central hepatic veins as well as intracellular gaps with higher doses. The TEM results demonstrated degradation of mitochondria indicating the direct acute effects of the aspartame on hepatic tissues which all were proportional with the increased doses. It is concluded that the daily ingestion of aspartame, even at lower doses, has acute effects and is dose dependant on hepatic cells which could exert further risks onto other tissues of consumers on the long run.
Stochastic Oscillators with Quadratic Nonlinearity Using WHEP and HPM Methods  [PDF]
Amnah S. Al-Johani
American Journal of Computational Mathematics (AJCM) , 2013, DOI: 10.4236/ajcm.2013.33027

In this paper, quadratic nonlinear oscillators under stochastic excitation are considered. The Wiener-Hermite expansion with perturbation (WHEP) method and the homotopy perturbation method (HPM) are used and compared. Different approximation orders are considered and statistical moments are computed in the two methods. The two methods show efficiency in estimating the stochastic response of the nonlinear differential equations.

Similarity Reduction of Nonlinear Partial Differential Equations  [PDF]
Amnah S. Al-Johani
Journal of Applied Mathematics and Physics (JAMP) , 2014, DOI: 10.4236/jamp.2014.23003

In this work, the HB method is extended to search for similarity reduction of nonlinear partial differential equations. This method is generalized and will apply for a (2 + 1)-dimensional higher order Broer-Kaup System. Some new exact solutions of Broer-Kaup System are found.

Higher-Order WHEP Solutions of Quadratic Nonlinear Stochastic Oscillatory Equation  [PDF]
Mohamed A. El-Beltagy, Amnah S. Al-Johani
Engineering (ENG) , 2013, DOI: 10.4236/eng.2013.55A009
Abstract: This paper introduces higher-order solutions of the quadratic nonlinear stochastic oscillatory equation. Solutions with different orders and different number of corrections are obtained with the WHEP technique which uses the WienerHermite expansion and perturbation technique. The equivalent deterministic equations are derived for each order and correction. The solution ensemble average and variance are estimated and compared for different orders, different number of corrections and different strengths of the nonlinearity. The solutions are simulated using symbolic computation software such as Mathematica. The comparisons between different orders and different number of corrections show the importance of higher-order and higher corrected WHEP solutions for the nonlinear stochastic differential equations.
Identification of Diabetic Retinal Exudates in Digital Color Images Using Support Vector Machine  [PDF]
R. F. Mansour, E. Md. Abdelrahim, Amna S. Al-Johani
Journal of Intelligent Learning Systems and Applications (JILSA) , 2013, DOI: 10.4236/jilsa.2013.53015

Support vector machine (SVM) has become an increasingly popular tool for machine learning tasks involving classification. In this paper, we present a simple and effective method of detect and classify hard exudates. Automatic detection of hard exudates from retinal images is worth-studying problem since hard exudates are associated with diabetic retinopathy and have been found to be one of the most prevalent earliest signs of retinopathy. The algorithm is based on Discrete Cosine Transform (DCT) analysis and SVM makes use of color information to perform the classification of retinal exudates. We prospectively assessed the algorithm performance using a database containing 1200 retinal images with variable color, brightness, and quality. Results of the proposed system can achieve a diagnostic accuracy with 97.0% sensitivity and 98.7% specificity for the identification of images containing any evidence of retinopathy.

The Impact of Samh Seeds on Blood Parameters of Experimental Animals
Norah Mohamad AL-Qahiz
Pakistan Journal of Nutrition , 2009,
Abstract: Samh seeds are cultivated in some regions of KSA and some people think that it can improve health. We aimed to find out the health benefits of Samh seeds. The seeds were obtained from Al Jouf, KSA and roasted for 5 min and grounded into flour. Its content from protein, fat and carbohydrate were determined. Thirty six normal male albino rats (100±5.0 g) were classified into 6 groups; control group that fed standard diet only, 5% Samh group received 5% of the seeds; 15% Samh group fed 15% of the seeds; high lipid diet group received high lipid diet (15% fat and 1% cholesterol); 5% Samh and high lipid group received high lipid diet plus 5% of the seeds and 15% Samh and high lipid diet group received high lipid diet plus 15% of the seeds. After 60 days, rats were fasted then anesthetized and blood samples were collected for determination of glucose, blood lipids, urea, creatinine, albumin, total protein, billirubin, calcium and iron. The results showed that the seeds are rich in protein (22.3±2.1%) and the administration of 5% of the seeds decreased glucose and BUN, while it elevated creatinine, albumin, total protein, cholesterol, triglycerides, HDL, calcium and iron. On the other hand the administration of 15% of the seeds decreased creatinine, albumin, cholesterol, triglycerides and LDL, while increased glucose, BUN, total bilirubin, HDL and iron. In conclusion the administration of 15% of Samh seeds flour reduce creatinine concentration and improve blood lipids especially cholesterol, HDL and LDL.
Management of Pleural Brucellosis: Case Report
Adel Alothman, Salih Bin Salih, Salwa Alothman and Ghassan Al Johani
Infectious Diseases: Research and Treatment , 2012,
Abstract: Background: Brucellosis is a zoonotic disease, with low incidence rate in developed countries, however the incidence rate in Middle Eastern countries remains high. Chest symptoms in brucellosis cases account for about 15% of the cases, but dealing with respiratory system involvement is rare particularly pleural involvement. Case Report: We report a case of a 60-year-old Saudi woman who was admitted with two months history of fever, productive cough, anorexia and weight loss, contact with sheep. She was ill looking, underweight and febrile while she was on treatment. Examination of the chest showed signs of pleural effusion on the right side with right infrascapular crepitations. Chest X-ray: showed pleural effusion and right LL infiltrates. CT chest: showed right loculated, pleural effusion. Pleural fluid examination showed exudative changes, on culture of pleural fluid, Brucella species grew. AFB in pleural fluid was negative. She was treated with Streptomycin, Doxycyclin and Ciprofloxacin . She improved within one week of treatment and was discharged, after 14 days on antibrucella therapy. Discussion: Pulmonary brucellosis is reported in medical literature occasionally but only few reports are available about pleural brucellosis. The challenge with pleural brucellosis and the association of loculated abscesses lies in therapy. Due to lack of previous information with such cases, we suggest that a period of more than six weeks is needed to treat this condition. We recommend that pleural brucellosis needs to be treated with at least two therapeutic agents for nine weeks.
Management of Pleural Brucellosis: Case Report
Adel Alothman,Salih Bin Salih,Salwa Alothman,Ghassan Al Johani
Infectious Diseases: Research and Treatment , 2009,
The Coxeter group
M. A. Albar,Norah Al-Saleh
International Journal of Mathematics and Mathematical Sciences , 2000, DOI: 10.1155/s0161171200002167
Abstract: We show that the Coxeter group Dn is the split extension of n−1 copies of Z2 by Sn for a given action of Sn described in the paper. We also find the centre of Dn and some of its other important subgroups.
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