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Search Results: 1 - 10 of 375162 matches for " Nina L?n "
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The Incidence of Late-Onset Pompe Disease in Subjects with Obstructive Sleep Apnea: A Cross-Sectional Study  [PDF]
Jan Stolk, Nina Ln, Jeannette Gast-Strookman, Zoltan Lukacs, Paulina Nieves Cobos, Poul Jennum
Open Journal of Internal Medicine (OJIM) , 2014, DOI: 10.4236/ojim.2014.43010
Abstract: Objectives: Current treatment options for obstructive sleep apnea syndrome often work to the sa-tisfaction of the patient, but in certain cases may not yield the required results for reasons that remain unclear. Late-onset Pompe disease may be a contributing factor in these circumstances. The aim of the present study was to determine the incidence of late-onset Pompe disease in a population diagnosed with obstructive sleep apnea. Material and Methods: The study had a cross-sec- tional, explorative design to assess the prevalence of late-onset Pompe disease in subjects with an established diagnosis of obstructive sleep apnea syndrome. In two different study mid to large size sleep clinics in Europe patients have been asked to donate a blood sample for the detection of ac-id-glucosidase enzyme activity. Results: Of a total of 544 patients with mild to severe obstructive sleep apnea, none had an acid maltase deficiency. Conclusions: Screening for Pompe disease in newly or recently detected OSA patients in mid to large size sleep clinics is not clinically effective. It should be confined to those subjects with OSA when upright forced vital capacity during spirometry is only moderately abnormal, because of the disproportionate diaphragmatic involvement.
Cómo evaluar el conocimiento que tienen los lectores acerca de sus procesos de lectura?
Paulina Nú?ez L.,Nina Crespo A.
Onomázein : Revista de Lingüística, Filología y Traducción , 1999,
Abstract: El objetivo principal de este estudio es presentar un instrumento de evaluación del conocimiento metacomprensivo, elaborado a partir de categorías emergentes durante la aplicación de dos entrevistas en profundidad a 50 sujetos de Valparaíso, Chile, que cursan primer a o de estudios universitarios. Entre las categorías de análisis referidas a partir de lo expresado por los lectores, es posible distinguir tres tipos de saberes distintos: de objetivos de lectura (por qué leo), de estrategias de comprensión (qué hago para comprender) y de experiencias o sensaciones metacognitivas que acompa an y afectan la lectura (qué siento). La intención ha sido dise ar, por medio de métodos cualitativos y cuantitativos, un sistema de evaluación que permita destacar la calidad de un conocimiento en torno a una categoría, más que la cantidad de ideas relacionadas con ella. Finalmente, el estudio presenta resultados generales obtenidos a partir de la aplicación de este instrumento a 52 alumnos que cursan 4o a o de Ense anza Media pertenecientes a establecimientos educacionales de Valparaíso, Chile. (The main objective of this study is to present a method of evaluation of metacomprehensive knowledge, obtained from a case study of 50 college freshmen students in Valparaíso, Chile, who took part in two interviews. Three types of "knowledge" can be inferred from the results: One related to "reading objectives" (Why do I read?), another, to comprehension strategies (How do I comprrehend?), and finally, one related to metacognitive sensations accompanying and affecting reading (What do I feel when I read?). Through qualitative and quantitative methods, a system of evaluation was designed that would allow priorizing the quality of knowledge around one category, rather than the amount of ideas related to it. Finally, general results obtained from the application of this instrument to 52 Senior High School students in Valparaíso, Chile, are also shown.)
Microbiological Quality of Asadero Cheese Manufactured with a Plant Based Coagulant from Solanum elaeagnifolium  [PDF]
Nina del Rocío Martínez-Ruiz, Sandra Flores Enriquez, Rosa Emma Vázquez-Nájera, José Alberto López-Díaz
Food and Nutrition Sciences (FNS) , 2013, DOI: 10.4236/fns.2013.47A009
Abstract: In Chihuahua, north Mexico, the berries of Solanum elaeagnifolium (trompillo or silverleaf nightshade) have been used in the manufacture of artisanal filata-type asadero cheese. Solanum elaeagnifolium is a wild plant that possesses proteases in its fruit; those enzymes exhibit general proteolytic activities, which are useful in traditional asadero cheesemaking as a rennet substitute. These type of cheese is softer than those made with rennin or chymosin due to their water content and proteolysis. Thus, the aim of this work was to explore microbiological susceptibility of asadero cheese made with an extract from ripe berries and compared with those elaborated with commercial rennet. Crude extract of such fruit was obtained by salting out with ammonium sulfate (40%). Cheeses were obtained by a standardized process only changing the enzyme, packaged in plastic bag or vacuum bag and storage at 4 - 6. The study included the analysis of spoilage bacteria (total aerobic count, yeasts and molds), indicators of hygiene (total coliforms and E. coli) and fecal contamination (fecal coliforms) after 1, 7, 14, 21 and 28 days of production. Although cheese made with S. elaeagnifolium had lower microbial growth, the aerobic count and yeasts and molds count of all cheese samples showing a 28 days shelf life. Total coliforms, in limits beyond the established ones by the Mexican legislation for human consumption with no effect of the enzyme type used for production, as well as for fecal coliforms. Differences were detected just for packaged method, suggesting that good manufacturing practices take place not the plant coagulant.
Sorption of Gadolinium (III) Ions by a Natural Clinoptilolite-Containing Tuff  [PDF]
Nina M. Kozhevnikova, Ekaterina N. Styazhkina
Open Journal of Physical Chemistry (OJPC) , 2013, DOI: 10.4236/ojpc.2013.33014

The equilibrium and kinetics of sorption of gadolinium (III) ions from sulfate solutions by a natural clinoptilolite containing tuff are studied. It is shown that gadolinium is completely extracted from dilute solutions (<0.002 M). The kinetic parameters of the sorption process are determined.

Dynamic Programming to Identification Problems  [PDF]
Nina N. Subbotina, Evgeniy A. Krupennikov
World Journal of Engineering and Technology (WJET) , 2016, DOI: 10.4236/wjet.2016.43D028
An identification problem is considered as inaccurate measurements of dynamics on a time interval are given. The model has the form of ordinary differential equations which are linear with respect to unknown parameters. A new approach is presented to solve the identification problem in the framework of the optimal control theory. A numerical algorithm based on the dynamic programming method is suggested to identify the unknown parameters. Results of simulations are exposed.
Tatiana L Kiseleva,Ekaterina Y Ladyiguina,Larisa N Frolova,Nina N Melnikova,Elena V Tsvetayeva,Julia A Smirnova
中国中药杂志 , 2010,
Tubular immunostimulating complex based on cucumarioside A2-2 and monogalactosyldiacylglycerol from marine macrophytes
Eduard Y Kostetsky, Nina M Sanina, Andrey N Mazeika, Alexander V Tsybulsky, Natalia S Vorobyeva, Valery L Shnyrov
Journal of Nanobiotechnology , 2011, DOI: 10.1186/1477-3155-9-35
Abstract: The cucumarioside A2-2 - cholesterol - MGalDG ratio of 6:2:4 (by weight) was found to provide the most effective formation of TI-complexes and the minimum hemolytic activity in vitro. Tubules of TI-complexes have an outer diameter of about 16 nm, an inner diameter of 6 nm, and a length of 500 nm. A significant dilution by the buffer gradually destroyed the tubular nanoparticles. The TI-complex was able to increase the immunogenicity of the protein antigens from Yersinia pseudotuberculosis by three to four times.We propose an optimized methodology for the preparation of homogeneous TI-complexes containing only tubular particles, which would achieve reproducible immunization results. We suggest that the elaborated TI-complexes apply as a universal delivery system for different subunit antigens within anti-infectious vaccines and enhance their economic efficacy and safety.Immunostimulating complexes (ISCOMs) are a commonly known adjuvant that represents a supramolecular combination of saponins from Quillaja saponaria, cholesterol, and phosphatidylcholine. It has been shown that ISCOMs display high adjuvant activity against a broad range of bacterial and viral antigens [1-5]. However, the side effects of ISCOMs are their toxicity, caused by the presence of the hemolytic saponins of Q. saponaria [2,6], a consistently insufficient adjuvant activity, and the absence of a satisfactory method of preparing them for industrial applications [6-9]. The development of the ISCOMATRIX? adjuvant, based on purified saponin fractions from Quil A substantially overcomes these shortcomings [1,10]. However, we proposed principally new biologically active components, glycoglycerolipids and triterpene glycosides isolated from marine macrophytes and invertebrates, respectively, to modify and optimize ISCOM vehicles for microbial antigens. The immunologically inert phospholipid phosphatidylcholine (PC) of ISCOMs was replaced by glycolipid monogalactosyldiacylglycerol (MGalDG) from marine mac
Achievement of Climate Planning Objectives among U.S. Member Cities of the International Council for Local Environmental Initiatives (ICLEI)  [PDF]
Margaret A. Reams, Kelsey W. Clinton, Nina S. N. Lam
Low Carbon Economy (LCE) , 2012, DOI: 10.4236/lce.2012.34018

In an effort to address climate change, many cities have joined the International Council for Local Environmental Initiatives (ICLEI) whose members commit to work toward five specific program objectives designed to reduce greenhouse gas emissions. This study examines the extent to which 257 member cities in the U.S.have been successful in achieving these program milestones and identifies factors that may explain variation in the performance of member cities. Potential influences on milestone attainment include socioeconomic, political and ideological characteristics of residents, length of ICLEI membership, existence of other climate programs within the state, and local environmental pressures. Multiple regression results indicate that length of membership is the strongest predictor of milestone attainment, regardless of local socioeconomic conditions, ideological and political orientations of residents, or other climate-related initiatives within the state. This finding supports the general effectiveness of ICLEI’s network organizational model and its outreach and education efforts. However, member cities facing more “climate stress”, including higher levels of hazardous air pollutants (HAP’s) and greater automobile use among residents are making slower progress. The findings yield insight into the conditions under which cities engaged in climate planning are more likely to succeed in reducing local greenhouse gas emissions-relevant information for planners, community stakeholders and administrators of organizations like ICLEI.

Measuring Capacity for Resilience among Coastal Counties of the U. S. Northern Gulf of Mexico Region  [PDF]
Margaret A. Reams, Nina S. N. Lam, Ariele Baker
American Journal of Climate Change (AJCC) , 2012, DOI: 10.4236/ajcc.2012.14016

Many have voiced concern about the long-term survival of coastal communities in the face of increasingly intense storms and sea level rise. In this study we select indicators of key theoretical concepts from the social-ecological resilience literature, aggregate those indicators into a resilience-capacity index, and calculate an index score for each of the 52 coastal counties of Louisiana, Texas, Mississippi, Alabama and Florida. Building upon Cutter’s Social Vulnerability Index work [1], we use Factor Analysis to combine 43 variables measuring demographics, social capital, economic re- sources, local government actions, and environmental conditions within the counties. Then, we map the counties’ scores to show the spatial distribution of resilience capacities. The counties identified as having the highest resilience capaci- ties include the suburban areas near New Orleans, Louisiana and Tampa, Florida, and the growing beach-tourist com- munities of Alabama and central Florida. Also, we examine whether those counties more active in oil and gas develop- ment and production, part of the region’s “energy coast”, have greater capacity for resilience than other counties in the region. Correlation analyses between the resilience-capacity index scores and two measures of oil and gas industry ac- tivity (total employment and number of business establishments within five industry categories) yielded no statistically significant associations. By aggregating a range of important contextual variables into a single index, the study demonstrates a useful approach for the more systematic examination and comparison of exposure, vulnerability and capacity for resilience among coastal communities.

Pulmonary artery sarcoma with angiosarcoma phenotype mimicking pleomorphic malignant fibrous histiocytoma: a case report
Olga L Bohn, Eric de León, Oscar Lezama, Nina P Rios-Luna, Sergio Sánchez-Sosa, Antonio Llombart-Bosch
Diagnostic Pathology , 2012, DOI: 10.1186/1746-1596-7-154
Abstract: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/2315906377648045 webcite.Primary sarcomas of the major blood vessels can be classified based on location in relationship to the wall (mural or intraluminal (also known as “intimal”) or by histologic type. Angiosarcomas are malignant tumors that arise from the endothelial lining of the blood vessels [1]. Pulmonary artery sarcomas (PAS) include two types: intimal sarcomas, presenting as intraluminal growing excrescences, and mural sarcomas, involving the pulmonary artery wall. PAS are rare tumors, with unknown and probably, underestimated incidence, which may show myofibroblastic, leiomyosarcomatous, osteosarcomatous, rhabdomyosarcomatous or angiosarcomatous differentiation [2]. Angiosarcoma of the pulmonary artery is a distinctive tumor and few cases have been reported to the date [2,3].A 36-year-old female presented to the clinic with a 3-month history of non-productive cough and weight loss. Her past medical history was unremarkable. Chest X-rays and a computed tomography (CT) scan showed two right perihilar lung masses, each measuring 3.5 and 2.5 cm in greater diameter, adjacent to the main right pulmonary artery (Figure 1). No extrapulmonary masses were identified by PET scan and CT; therefore, metastatic disease was excluded. A bronchoscopy was performed and transbronchial biopsies were taken but were non diagnostic. She had a thoracoscopic exploration and an open-lung biopsy. A pathology report showed a malignant fibrous histiocytoma (MFH) of the lung. A right pneumonectomy was performed and she required 2 days in the ICU; pulmonary artery hypertension and tachycardia developed, which resolved with digoxin and diltiazem.The specimen consisted of a total right lung, weighing 994 grams and measuring 35 × 11 × 7 cm. On the anterior aspect of the right upper lobe, two masses that abut pleural surfaces were identified. Cut sections showed a right pulmonary artery t
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