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Search Results: 1 - 10 of 122797 matches for " Nilberto Robson Falc?o do; "
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Identification of mechanisms involved in the relaxation of rabbit cavernous smooth muscle by a new nitric oxide donor ruthenium compound
Cerqueira, Jo?o Batista Gadelha de;Gonzaga-Silva, Lúcio Flávio;Silva, Francisco Ordelei Nascimento da;Cerqueira, Jo?o Victor Medeiros de;Oliveira, Ricardo Reges Maia;Moraes, Maria Elisabete Amaral de;Nascimento, Nilberto Robson Falco do;
International braz j urol , 2012, DOI: 10.1590/S1677-55382012000500015
Abstract: purpose: the aim of this study was to evaluate the relaxation in vitro of cavernous smooth muscle induced by a new no donor of the complex nitrosil-ruthenium, named trans-[ru(nh3)4(caffeine)(no)]c13 (rut-caf) and sodium nitroprusside (snp). materials and methods: the tissues, immersed in isolated bath systems, were pre-contracted with phenilephrine (pe) (1 μm) and then concentration-response curves (10-12 - 10-4 m) were obtained. to clarify the mechanism of action involved, it was added to the baths odq (10 μm, 30 μm), oxyhemoglobin (10 μm), l-cysteine (100 μm), hydroxicobalamine (100 μm), glibenclamide, iberotoxin and apamine. tissue samples were frozen in liquid nitrogen to measure the amount of cgmp and camp produced. results: the substances provoked significant relaxation of the cavernous smooth muscle. both rut-caf and snp determined dose-dependent relaxation with similar potency (pec50) and maximum effect (emax). the substances showed activity through activation of the soluble guanylyl cyclase (sgc), because the relaxations were inhibited by odq. oxyhemoglobin significantly diminished the relaxation effect of the substances. l-cysteine failed to modify the relaxations caused by the agents. hydroxicobalamine significantly diminished the relaxation effect of rut-caf. glibenclamide significantly increased the efficacy of rut-caf (pec50 4.09 x 7.09). there were no alterations of potency or maximum effect of the substances with the addition of the other ion channel blockers. rut-caf induced production of significant amounts of cgmp and camp during the relaxation process. conclusions: in conclusion, rut-caf causes relaxation of smooth muscle of corpus cavernosum by means of activation of sgc with intracellular production of cgmp and camp; and also by release of no in the intracellular environment. rut-caf releases the no free radical and it does not act directly on the potassium ion channels.
Raquianestesia contínua em paciente submetido à gastrectomia parcial: relato de caso
Pitombo, Patrícia Falco;Moura, Robson;Miranda, Ricardo;
Revista Brasileira de Anestesiologia , 2009, DOI: 10.1590/S0034-70942009000400011
Abstract: background and objectives: due to the high incidence of technical and neurological complications, continuous spinal blocks were not performed for several years. with the advent of intermediate catheters the technique has been used more often and gaining acceptance among anesthesiologists. the objective of this report was to demonstrate the usefulness of the technique as a viable alternative for medium and major size surgeries. case report: this is a 58 years old female patient, weighing 62 kg, physical status asa i, with a history of migraines, low back pain, and prior surgeries under spinal block without intercurrence. the patient was scheduled for exploratory laparotomy for a probable pelvic tumor. after venoclysis with an 18g catheter, monitoring with cardioscope, non-invasive blood pressure and pulse oximetry was instituted; she was sedated with 2 mg of midazolam and 100 ?g of fentanyl, and placed in left lateral decubitus. the patient underwent continuous spinal block through the median approach in l3-l4; 9 mg of 0.5% hyperbaric bupivacaine and 120 ?g of morphine sulfate were administered. inspection of the abdominal cavity revealed a gastric stromal tumor that required an increase in the incision for a partial gastrectomy. a small dose of hyperbaric solution was required for the entire procedure, which was associated with complete hemodynamic stability. postoperative admission to the icu was not necessary; the patient presented a good evolution without complaints and with a high degree of satisfaction. she was discharged from the hospital after 72 hours without intercurrence. conclusions: intermediate catheters used in continuous spinal blocks have shown the potential to turn it an attractive and useful technique in medium and large size surgeries and it can even be an effective alternative in the management of critical patients to whom hemodynamic repercussions can be harmful.
Development and Results of an Instrument to Search for Competences and Abilities in Information Technology  [PDF]
Juliana Teixeira da Camara Reis, Izabel Hazin, Jorge Tarcísio da Rocha Falco, Luciano Meira, Pedro Bendassolli, Amanda Guerra, Taciana Pontual Falco, Apuena Vieira Gomes, Marcel Vinícius Medeiros Oliveira, José Ivonildo do Rêgo
Creative Education (CE) , 2015, DOI: 10.4236/ce.2015.622244
Abstract: This article presents an analysis of the selection process of students from both private and public high schools in the state of Rio Grande do Norte (Northeast of Brazil), in order to form the first group of the Information Technology technical course of the Metrópole Digital project at the Federal University of Rio Grande do Norte (UFRN). The selection instrument consists of a written exam built on the basis of a set of matrices that depict relevant competences and abilities expected from the students. Data concerning the profile of distribution of performance per exam question are presented, together with empirical evidences of the effectiveness of the proposed competence matrices in the selection process. The correlation very fied among the matrices compounding the instrument and scores in courses, and the instrument as a wholeand scores in courses is moderate to strong (rS = 0.6 and rS = 0.7; p < 0,05). The association between the criterion variables (Average of Performance in the Basic Moduleof courses) and the explicative variables (Total score in the selection instrument (QTot) and each of the five compounding matrices) is moderate (rS=0.51, p = 0.001), and the matrices and QTot are jointly responsible for 25% of the variance of the performance in the basic module. The regression coefficient for matrix 1 is 1.38 (CI of 95% = 1.07-1.68); for matrix 2 it was 0.65 (CI of 95% = 036-0.95); for matrix 3, 1.2 (CI of 95% = 0.92 - 1,55); matrix 4 0,76 (CI of 95% = 0.45-1.06); matrix 5 1.08 (CI of 95% = 0.78-1.39). The effects of student-descriptive independent variables on performance in the exam are also presented and discussed, and predictive relationships between performance in the exam and performance in the disciplines of the course are verified. Data collected allow concluding that the instrument of selection proposed fits well the aim of forming a group of students to undertake a technical course in the area of information technology.
High Abilities and Information Technologies: The Talento Metrópole Brazilian Program  [PDF]
Izabel Hazin, Jorge Falco, Ivonildo do Rêgo, Apuena Gomes, Priscila Andrade, Laura Arag?o, Ana Carolina Sales, Juliana Reis, Mayara Wenice
Creative Education (CE) , 2015, DOI: 10.4236/ce.2015.67064
Abstract: The study presents the Brazilian experience of the Talento Metrópole program, linked to the Digital Metropolis Institute of the Federal University of Rio Grande do Norte, located in Brazil’s Northeast. The Talento Metrópole program aims to develop the interest of young people with high abilities/intellectual giftedness in scientific research, expand skills and abilities, and get creative in the fields of information technology and its interfaces, always seeking innovation and entrepreneurship. It also aims to create opportunities for the dissemination of new knowledge and to explore career opportunities related to this area, with the purpose of creatively inserting young people into the labor market and into solidary social participation. The participants are students from public and private schools, colleges and universities, aged between 13 and 21 years. The steps that comprise the structure of the program are described and characterized. In addition, the selection process for admission to the program is described, with emphasis on the stage which illustrates the development and characterization of the instrument which investigate the sources of skills and expertise subjacent to the field of information technology.
Cidade fragmentada: os usos das redes elétricas em favelas do município de Vitória-ES
Cláudio Zanotelli,Lucas do Carmo Falco de Lacerda,Victor Araújo Galv?o
Geografares , 2008,
Abstract: O texto trata da fragmenta o sócio-espacial na cidade a partir da teoria dos dois circuitos urbanos de Milton Santos e de reflex es diversas sobre a segrega o e a fragmenta o. Busca compreender o acesso às redes elétricas como reveladoras desse processo nos bairros da Penha e da Fonte Grande no município de Vitória – ES. A infra-estrutura da rede elétrica nesses lugares é precária, bem como o consumo médio das residências relativamente elevado em fun o das instala es ruins e dos inúmeros eletrodomésticos possuídos pelas famílias. As tarifas em rela o à renda média dos habitantes s o relativamente elevadas: os valores pagos por kWh para as residências s o iguais para todas as classes sociais e bem superiores àqueles da grande indústria. O meio encontrado para se suprir em eletricidade, por uma parte mais pobre dos habitantes, é o seu uso ilícito. Há uma criminaliza o de parcelas das popula es incitadas ao consumo, mas sem meios para arcar com os custos e que acabam lan ando m o de expedientes ilegais para se suprir em eletricidade. Isso refor a os processos de fragmenta o territorial e de desfilia o das popula es que ali vivem.
Aduba o NK no desenvolvimento e na concentra o de macronutrientes no florescimento do feijoeiro
Lima Eduardo do Valle,Arag?o Carlos Alberto,Morais Otoniel Magalh?es,Tanaka Robson
Scientia Agricola , 2001,
Abstract: O nitrogênio e o potássio s o os elementos mais absorvidos e exportados pelo feijoeiro, sendo a aduba o mineral entre os produtores bastante variável quanto as doses aplicadas. Este trabalho avalia os efeitos de doses de N (0, 60, 80, 100 e 120 kg ha-1) e K2O (0, 60 e 120 kg ha-1) no desenvolvimento do feijoeiro, por meio do número de unidades estruturais, peso de material fresco e seco, e a concentra o de macronutrientes no florescimento. O experimento foi realizado em Botucatu, SP., em túnel plástico, utilizando-se a cultivar 'Pérola'. Duas plantas foram cultivadas em vasos de 15 L, preenchidos com terra de Latossolo Vermelho Distrófico típico, textura média, por 50 dias. As doses de NK foram parceladas em cobertura aos 20 e 40 dias após semeadura. As variáveis estudadas foram influenciadas pela intera o entre as doses de N e K. A aduba o parcelada com N via solo, independentemente das doses utilizadas ou da fertiliza o com K, aumenta a produ o de matéria seca sem interferir nos teores de N da parte aérea do feijoeiro, assim como os de K, Ca e Mg. A omiss o de N em cobertura reduz o teor de clorofila, diminuindo a produ o de matéria seca, mas n o interferindo no número de flores. Os níveis de K utilizados n o diminuíram os teores de Ca e Mg da planta.
O tabagismo em um município de pequeno porte: um estudo etnográfico como base para gera??o de um programa de saúde pública
Falco, Thales Jenner de Oliveira;Costa, Iris do Céu Clara;
Jornal Brasileiro de Pneumologia , 2008,
Abstract: objective: to outline the prevalence of smoking in the city of parazinho, brazil, with the objective of generating data on which to base a plan of action for smoking control programs in the city. methods: a questionnaire was applied to 150 people (25.6% of whom were smokers) by community health agents during home visits. the questionnaire comprised 30 objective and subjective questions to collect social and biological information on smokers in urban and rural areas. results: the data were analyzed using descriptive statistics, and the principal findings were as follows: the prevalence of smoking was higher among males (57.8%); most of the interviewees started smoking at an early age (45% before the age of 12); economic conditions constituted a contributing factor (66% of the smokers interviewed earned less than the minimum wage); most of the interviewees reported difficulty in kicking the habit (44.6% reported living with a smoker, and 80% had a friend who smoked); there was a high prevalence of tobacco-related diseases (56.6% had respiratory problems); and there was concomitant alcohol use in 52% of the smokers. conclusion: this outline can be used in the generation of a local program of smoking prevention and control. such a program is, in fact, under development. a team of professionals has received training in a 'minimal, intensive approach to the smoker', and a municipal outpatient clinic for the treatment of nicotine dependence has been inaugurated.
Atualiza??o das diretrizes de ressuscita??o cardiopulmonar de interesse ao anestesiologista
Falco, Luiz Fernando dos Reis;Ferez, David;Amaral, José Luiz Gomes do;
Revista Brasileira de Anestesiologia , 2011, DOI: 10.1590/S0034-70942011000500013
Abstract: background and objectives: the new cardiopulmonary resuscitation (cpr) guidelines emphasize the importance of high-quality chest compressions and modify some routines. the objective of this report was to review the main changes in resuscitation practiced by anesthesiologists. contents: the emphasis on high-quality chest compressions with adequate rate and depth allowing full recoil of the chest and with minimal interruptions is highlighted in this update. one should not take more than ten seconds checking the pulse before starting cpr. the universal relationship of 30:2 is maintained, modifying its order, initiating with chest compressions, followed by airways and breathing (c-a-b instead of a-b-c). the procedure "look, listen, and feel whether the patient is breathing" was removed from the algorithm, and the use of cricoid pressure during ventilations is not recommended any more. the rate of chest compressions was changed for at least one hundred per minute instead of approximately one hundred per minute, and its depth in adults was changed to 5 cm instead of the prior recommendation of 4 to 5 cm. the single shock is maintained, and it should be of 120 to 200 j when it is biphasic; and 360 j when it is monophasic. in advanced cardiac life support, the use of capnography and capnometry to confirm intubation and monitoring the quality of cpr is a formal recommendation. atropine is no longer recommended for routine use in the treatment of pulseless electrical activity or asystole. conclusions: updating the phases of the new cpr guidelines is important, and continuous learning is recommended. this will improve the quality of resuscitation and survival of patients in cardiac arrest
O tabagismo em um município de pequeno porte: um estudo etnográfico como base para gera o de um programa de saúde pública Smoking in a small city: an ethnographic study to serve as a base for the creation of a public health program
Thales Jenner de Oliveira Falco,Iris do Céu Clara Costa
Jornal Brasileiro de Pneumologia , 2008,
Abstract: OBJETIVO: Tra ar um diagnóstico da prevalência do tabagismo em Parazinho (Rio Grande do Norte), visando subsidiar o planejamento de programas de controle do tabagismo no município. MéTODOS: Foi aplicado um questionário entre 150 pessoas (25,6% do universo de fumantes), contendo 30 perguntas objetivas e subjetivas, com a finalidade de reunir informa es sociais e biológicas sobre esses usuários de tabaco das zonas urbana e rural, pelos agentes comunitários de saúde, durante visitas domiciliares. RESULTADOS: Os dados foram analisados pela estatística descritiva, tendo como principais resultados: maior prevalência de fumantes do sexo masculino (57,8%); início precoce do consumo de tabaco entre a maioria dos entrevistados (antes dos 12 anos em 45% deles); condi o econ mica como agente agravante desta temática (66% dos entrevistados ganhavam até um salário mínimo); dificuldade encontrada para o abandono desse comportamento (44,6% deles relataram haver fumante em casa; e 80%, terem algum amigo fumante); doen as tabaco-relacionadas (56,6% dos fumantes tinham problemas respiratórios); além da associa o do uso do tabaco à ingest o alcoólica em 52% dos fumantes. CONCLUS O: Entende-se que este diagnóstico servirá de base para a gera o de um programa local de preven o e controle do tabagismo, o que na prática já come a a ser viabilizado a partir da capacita o de uma equipe para 'abordagem mínima e intensiva do fumante', além da implanta o a médio prazo de um ambulatório municipal de assistência a esses dependentes. OBJECTIVE: To outline the prevalence of smoking in the city of Parazinho, Brazil, with the objective of generating data on which to base a plan of action for smoking control programs in the city. METHODS: A questionnaire was applied to 150 people (25.6% of whom were smokers) by community health agents during home visits. The questionnaire comprised 30 objective and subjective questions to collect social and biological information on smokers in urban and rural areas. RESULTS: The data were analyzed using descriptive statistics, and the principal findings were as follows: the prevalence of smoking was higher among males (57.8%); most of the interviewees started smoking at an early age (45% before the age of 12); economic conditions constituted a contributing factor (66% of the smokers interviewed earned less than the minimum wage); most of the interviewees reported difficulty in kicking the habit (44.6% reported living with a smoker, and 80% had a friend who smoked); there was a high prevalence of tobacco-related diseases (56.6% had respiratory probl
Histological Evaluation of the Bone Repair Using Mineral Trioxide Aggregate Combined to a Material Carrier Evaluación Histológica del Proceso de Reparación ósea Utilizando Agregado Trióxido Mineral Combinado a un Material Cargador
Hilmo Barreto Leite Falco-Filho,Jo?o Paulo Mardegan Issa,Cássio do Nascimento,Mamie Mizusaki Iyomasa
International Journal of Morphology , 2007,
Abstract: The aim of this study was to present a possible carrier for MTA, monoolein gel, with the objective to maintain this material in the place that was inserted and verify if this procedure is able to optimize its action. The data were evaluated by histomorphometric method and submitted to statistical analysis. The histological responses observed in this study indicate that the MTA is a reliable material and should be considered effective in bone periapical defects and the monoolein gel was capable to maintain the MTA in situ El objetivo de este estudio fue presentar el gel de monoleína como un posible cargador para el MTA y verificar si es capaz de optimizar su acción. Los datos obtenidos fueron evaluados por métodos histomorfométricos y sometidos a análisis estadístico. El resultado histológico reveló que el MTA es un material efectivo para utilizarlo en defectos óseos periapicales y que el gel de monoleína es capaz de mantener el MTA in situ
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