Abstract:
Objective The 2010 WHO antiretroviral therapy (ART) guidelines have resulted in increased tenofovir use. Little is known about tenofovir-induced chronic kidney disease (CKD) in HIV-infected Vietnamese with mean body weight of 55 kg. We evaluated the prevalence and risk factors of CKD in this country. Design Cross-sectional study was performed. Methods Clinical data on HIV-infected Vietnamese cohort were collected twice a year. To evaluate the prevalence of CKD, serum creatinine was measured in 771 patients in October 2011 and April 2012. CKD was defined as creatinine clearance less than 60 ml/min at both time points. Multivariate logistic regression was used to determine the factors associated with CKD Results Tenofovir use increased in Vietnam from 11.9% in April 2011 to 40.3% in April 2012. CKD was diagnosed in 7.3%, of which 7% was considered moderate and 0.3% was severe. Multivariate analysis of October-2011 data identified age per year-increase (OR: 1.229, 95%CI, 1.170-1.291), body weight per 1 kg-decrement (1.286, 1.193-1.386), and tenofovir use (2.715, 1.028-7.168) as risk factors for CKD. Conclusions Older age, low body weight and tenofovir use were independent risk factors for CKD in Vietnam. Further longitudinal study is required to evaluate the impact of TDF on renal function in Vietnam and other countries with small-body weight patients.

Abstract:
A cross-sectional study was carried out to investigate the seroprevalence of M. bovis. A total of 606 serum samples were randomly collected from dairy cows in Ho Chi Minh City, Vietnam. Commercial ELISA kit was used for detection of antibody to M. bovis. The results indicated that overall seroprevalence was 80.2% (486/606). There were no significant differences between regions or age categories (P > 0.05). Degree of infection to M. bovis commonly distributed at positive degree 1 (68.5%) and 2 (24.1%). Seroprevalence at highest positive degree 4 were found in District 9, District 12 and Thu Duc (6.7%, 6.3% and 1.6%, respectively). This study is the first report of seroprevalence of M. bovis in Vietnam. The results suggested that M. bovis was spreading among dairy cow populations although degree of positivity was low. It should be considered as a high risk pathogen to dairy cows in Vietnam.

Abstract:
Background As dengue spreads to new geographical regions and the force of infection changes in existing endemic areas, a greater breadth of clinical presentations is being recognised. Clinical experience suggests that adults manifest a pattern of complications different from those observed in children, but few reports have described the age-related spectrum of disease in contemporaneous groups of patients recruited at the same geographical location. Methodology/Principal Findings Using detailed prospectively collected information from ongoing studies that encompass the full spectrum of hospitalised dengue cases admitted to a single hospital in southern Vietnam, we compared clinical and laboratory features, management, and outcome for 647 adults and 881 children with confirmed dengue. Signs of vascular leakage and shock were more frequent and more severe in children than adults, while bleeding manifestations and organ involvement were more common in adults. Additionally, adults experienced significantly more severe thrombocytopenia. Secondary infection but not serotype was independently associated with greater thrombocytopenia, although with a smaller effect than age-group. The effect of age-group on platelet count was also apparent in the values obtained several weeks after recovery, indicating that healthy adults have intrinsically lower counts compared to children. Conclusions/Significance There are clear distinctions between adults and children in the pattern of complications seen in association with dengue infection, and these depend partly on intrinsic age-dependent physiological differences. Knowledge of such differences is important to inform research on disease pathogenesis, as well as to encourage development of management guidelines that are appropriate to the age-groups at risk.

Abstract:
In the present work we obtain existence results for Hammerstein type integro-differential inclusions in a finite dimensional space for the cases when the integral multifunction satisfies upper Caratheodory conditions and when it is almost lower semicontinuous.

Abstract:
The aim of this work is to give a combinatorial way to describe all irreducible representations in case the super-dimension of $V$ is $(3|1)$.

Abstract:
We give some sufficient conditions on complex polynomials P and Q to assure that the algebraic plane curve P(x)-Q(y)=0 has no irreducible component of genus 0 or 1. Moreover, if deg (P)=deg (Q) and if both P, Q satisfy Hypothesis I introduced by H. Fujimoto, our sufficient conditions are necessary.

Abstract:
In this paper, we consider second order differential inclusions with periodic boundary conditions. We obtain the existence of positive solutions and of continuous branches of positive solutions.

Abstract:
Let consider $n$ natural numbers $a\_1 ,\ldots , a\_{n} $. Let $S$ be the numerical semigroup generated by $a\_1 ,\ldots , a\_{n} $. Set $A=K[t^{a\_1}, \ldots , t^{a\_n}]=K[{x\_1}, \ldots , {x\_n}]/I$. The aim of this paper is: \begin{enumerate}\item Give an effective pseudo-polynomial algorithm on $a\_1$, which computes The Ap{\'e}ry set and the Frobenius number of $S$. As a consequence it also solves in pseudo-polynomial time the integer knapsack problem : given a natural integer b, b belongs to $S$?\item The \gbb of $I$ for the reverse lexicographic order to $x\_n,\ldots ,x\_1$, without using Buchberger's algorithm. \item $\ini{I} $ for the reverse lexicographic order to $x\_n,\ldots ,x\_1$.\item $A$ as a $K[t^{ a\_1 }]$-module. \end{enumerate} We dont know the complexity of our algorithm. We need to solve the "multiplicative" integer knapsack problem: Find all positive integer solutions $({k\_1}, \ldots , {k\_n})$ of the inequality $\prod\_{i=2}^n (k\_i+1)\leq a\_1+1$. This algorithm is easily implemented. The implementation of this algorithm "frobenius-number-mm", for $n=17 $, can be downloaded in \hfill\breakhttps://www-fourier.ujf-grenoble.fr/~morales/frobenius-number-mm

Abstract:
Let consider $n$ natural numbers $a\_1 ,\ldots , a\_{n} $. Set $A=K[t^{a\_1}, \ldots , t^{a\_n}]=K[{x\_1}, \ldots , {x\_n}]/I$. Our aim is to describe explicitly:* The \gbb of $I$ for the reverse lexicographic order to $x\_n,\ldots ,x\_1$, without using Buchberger's algorithm.* $\ini{I} $ for the reverse lexicographic order to $x\_n,\ldots ,x\_1$.* $A$ as a $K[t^{ a\_1 }]$-module.* The Ap{\'e}ry set and the Frobenius number. The implementation of this algorithm "frobenius-number-mm" can be downloaded in \hfill\breakhttps://www-fourier.ujf-grenoble.fr/~morales/frobenius-number-mm