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Search Results: 1 - 10 of 461 matches for " Neonate "
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A lightweight mainstream capnometer with very low dead space volume is useful monitor for neonates with spontanous and mechanical ventilation: Pilot study  [PDF]
Daijiro Takahashi, Miyu Matsui, Takehiko Hiroma, Tomohiko Nakamura
Open Journal of Pediatrics (OJPed) , 2012, DOI: 10.4236/ojped.2012.22021
Abstract: Objects: The purpose of this study was to observe a correlation between PETCO2 and PaCO2 in intubated neonates under intermittent mandatory ventilation with spontaneous breathing. Material and methods: A total of 55 paired PETCO2 measured by mainstream capnometry and PaCO2 values were obtained from 4 intubated neonates in our neonatal intensive care units at Nagano Children’s Hospital, Nagano, Japan. Results: PETCO2 and PaCO2 were significantly correlated (r2 = 0.928, p < 0.0001). For samples in ventilated neonates with spontaneous breathing, maximum PETCO2 and mean PETCO2 correlated strongly with PaCO2 (maximum PETCO2: r2 = 0.9401, p < 0.0001; mean PETCO2: r2 = 0.8587, p < 0.0001). Although PaCO2 also correlated with minimum PETCO2 (r2 = 0.2884, p < 0.01) in ventilated infants with spontaneous breathing, a significant difference was seen with maximum PETCO2 (p < 0.05) and mean PETCO2 (p < 0.05) in the correlation coefficient r between PaCO2 and PETCO2. Conclusion: Present study showed that a good correlation exists between PETCO2 and PaCO2 in intubated neonates under intermittent mandatory ventilation with spontaneous breathing. Lightweight with low amounts of dead space mainstream capnometry can be used as noninvasive monitor in incubated neonates with spontaneous breathing.
Transplacental transmission of EDTA dependent pseudothrombocytopenia in a neonate  [PDF]
Ali Bay, Ercan Sivasli, Safak Taviloglu, Goksel Leblebisatan, Enes Coskun, Unal Uluca
Open Journal of Pediatrics (OJPed) , 2011, DOI: 10.4236/ojped.2011.13011
Abstract: Verifying platelet counts can prevent unwarranted diagnostic tests and transfusions. In case of thrombocytopenia, if the clinical picture and history do not suggest bleeding tendency, one should always perform peripheral blood smear by directly obtaining blood by finger puncture before doing any further tests. If the peripheral blood smear exhibits platelet clumps, pseudothrombocytopenia should always be remembered. In this case, we present a neonate with a diagnosis of transplacental transmission of EDTA-dependant pseudothrombocytopenia.
Antibiotic sensitivity pattern of common bacterial pathogens in NICU and neonatal ward in Hamedan province of Iran  [PDF]
Alireza Monsef, Fatemeh Eghbalian
Health (Health) , 2010, DOI: 10.4236/health.2010.26094
Abstract: Bacterial pathogens and drug resistance are different in hospitals of each country. In this study we determined bacterial path- ogens and drug sensitivity in the neonatal ward and neonatal intensive care unit (NICU) in Ekbatan hospital in Hamedan. This cross-sectional descriptive study was done on 1150 hospitalized neonates in neonatal and NICU wards of Ekbatan hospital of the Hamadan university of medical sciences from September 2004 to September 2006. Blood, cerebrospinal fluid (CSF), urine, stool, eye excretion, synovial fluid, umbilical secretion and ascitic fluid were evaluated. Positive cultures were evaluated for antibiotic resistance with disk diffusion test methed. All of the data in questionnaires was analyzed with SPSS 13. Cultures including blood, urine, CSF , stool, eye excretion, synovial fluid, umbilical secretion and ascitic fluid was done in 417 neonates (833 cultures). These cultures were including: urine, 323 cases (38.8%) blood 293 cases (35.2%), CSF 180 cases (21.6%) , stool 17 cases (2%), eye secretion 16 cases (1.9%) and other secretions (synovial, umbilical, etc) 4 cases (0.5%). The cultures were positive in 105 cases (25.2%). 60 male neonates (57.1%) and 45 female neonates (42.9%) were culture positive. The most common microorganisms were E coli 66.7% (70 cases), Klebsiella 10.5% (11 cases). Drug resistance was high in these microorganisms. The most common microorganisms were Ecoli and klebsiella. Drug resistance was high in the isolated microorganisms.
RNA Interference Mediated Silencing of Tissue Factor in Human Umbilical Vein Endothelial Cells  [PDF]
Xiaojuan Yin, Zhu Chen, Weiqin Zhou, Wen Tang, Zhichun Feng
Open Journal of Obstetrics and Gynecology (OJOG) , 2018, DOI: 10.4236/ojog.2018.85054
Abstract: Objective: To construct to silence tissue factor (TF) expression in Human Umbilical Vein Endothelial Cells (HUVECs) for providing evidence of the gene therapy and prevention of coagulation dysfunction in placental abruption (PA) neonates. Methods: Cultured HUVECs in vitro were divided into control group and PA group, each including non-prevention, scramble siRNA and TF-siRNA subgroups. pENTRTM/U6-shRNA/TF vector expressing TF were constructed and transfected into HUVECs. The mRNA expression of TF was tested with RT-PCR, and TF protein expression was detected with immunofluorescence staining. Results: Monolayer HUVECs with short-rod and short spindle shaped were adherent to the bottom, forming paving stone arrangement. The TF mRNA expression was significantly different between control group and PA group (P < 0.01) and among different subgroups (P < 0.01). In non-prevention subgroups, significant difference was observed in TF mRNA expression between control group and PA group (P < 0.05). Significant difference in TF mRNA expression was found in false-prevention subgroups (P < 0.05). The TF mRNA expression was
Candidiasis congénita en un recién nacido de muy bajo peso
Bustos B.,Raúl; Copaja L.,Daniel; Bancalari M.,Aldo;
Revista chilena de pediatría , 2003, DOI: 10.4067/S0370-41062003000200008
Abstract: systemic candidiasis has become an important cause of nosocomial infections in very low birth weight infants (vlbw). in this vulnerable population candidal infection may be disseminated, be congenital or related to intravenous lines. congenital candidiasis is a rare disorder acquired in utero. in this report we describe a vlbw infant (24 weeks of gestational age and birth weight of 630gm) with congenital candidiasis, and discuss the risk factors, clinical and laboratory findings, treatment and the outcome of this condition based on a review of reported cases in the literature
Evaluation of Neonates with Ventriculitis
Ferda Ozlu,Hacer Yapicioglu,Kenan Ozcan,Nejat Narli
Cukurova Medical Journal , 2013,
Abstract: Backgroud: Neonatal meningitis and ventriculitis still remain a problem with high mortality in spite of systemic and intraventricular antibiotics. Ventriculitis due to repeated taps is a serious problem of posthemorragic hydrocephalus in preterm infants. Methods: In this study, we evaluated 16 infants with ventriculitis followed at Cukurova University Faculty of Medicine Neonatal Intensive Care Unit between January 1999-December 2004. Results: Mean gestational week was 33± 5 (25-40) weeks and mean birth weight was 2096 ± 912 (980-3500) grams. Venticulitis was diagnosed at 38 ± 22 days. Eleven of the infants had intraventricular hemorrhage and 15 had hydrocephalus, 5 of whom had congenital hydrocephalus. Drainage of CSF was performed by taps in 13 infants. Gram negative microorganisms (Klebsiella pneumonia, Pseudomonas aeruginosa) were predominating in cultures. Both intravenous and intraventricular antibiotic treatment was performed according to the cerebrospinal fluid cultures. Vancomycine and amicasine as intraventricular therapy were performed for 28 ±17 days. Cerebrospinal fluid protein levels increased significantly at 8 infant during intraventricular therapy. Mean cerebrospinal fluid protein at the begining of intraventricular treatment was 624.1± 429.1 (109-1330) mg/dl while on 14th day of treatment it was 993.7± 582.2 (89-1750) mg/dl. Seven of the infants were ventriculoperitoneal shunted 6 of them were reinfected. Seven of the infants were died during treatment, 1 infant with ventriculoperitoneal shunt was treated and 8 infants were discharged during treatment because of parents refusal of therapy. Conclusion: Despite the new treatment regimens, the ventriculitis still remains a problem because of nonstandardized practice in neonatal care. [Cukurova Med J 2013; 38(4.000): 553-558]
Neonatal Empyema Thoracis
J Mazumdar,S Sen
Journal of Nepal Paediatric Society , 2014, DOI: 10.3126/jnps.v34i1.8233
Abstract: Empyema thoracis, is a rare cause of respiratory distress in neonates. Only a few cases of neonatal empyema thoracis are described in medical literature. Empyema thoracis is not a well known entity in the neonates. It is fulminant with rapid progression with a high mortality. Compounding the problem is its uncertain etiopathogenesis and lack of definite treatment guidelines. We shall describe one case of neonatal empyema in a newborn aged five days caused by Pseudomonas aeruginosa . The neonate died subsequently. DOI: http://dx.doi.org/10.3126/jnps.v34i1.8233 ? J Nepal Paediatr Soc 2014;34(1):65-67 ?
Spontaneous neonatal pneumomediastinum  [PDF]
Kiran Kumar Balegar V, Nadia Badawi, Arieta Fa’asalele, Kathryn Carmo
Open Journal of Pediatrics (OJPed) , 2011, DOI: 10.4236/ojped.2011.13010
Abstract: Radiolucency in the superior mediastinum may be caused by a congenital cystic mass or pneumomediastinum. Most cases of pneumomediastinum occur in preterm newborns with surfactant deficiency receiving treatment with positive pressure ventilation. Spontaneous pneumomediastinum in term neonates is also rarely reported. We report the outcome for a term neonate with respiratory distress who was transferred for surgical evaluation of a cystic superior mediastinal mass.
Less hypoglycaemias in single room maternity care  [PDF]
Peter Gerrits, Maartje de Hosson, Ben Semmekrot, Jan Sporken
Open Journal of Pediatrics (OJPed) , 2013, DOI: 10.4236/ojped.2013.33031
Abstract: In January 2006, the Canisius-Wilhelmina Hospital introduced the concept of Single Room Maternity Care (SMRC) by realizing 13 labour rooms for mother, infant and partner. Benefits of this new care concept not only include maternal satisfaction and increased staff satisfaction, but also significant health benefits for the neonate. Since the introduction of the concept, we registered a sharp decrease in the number of hypoglycaemias (from 15.6% in 2005 to 2.5% in 2009). Varying causes, such as successful breastfeeding and/or improved attachment between mother and infant may contribute to the decrease of hypoglycaemias.
Cor-triatriatum dexter with pulmonary hypertension in a neonate  [PDF]
Bijay Kumar Meher, Pradeep S, Leena Das, Priyadarsi Tripathy
Open Journal of Pediatrics (OJPed) , 2013, DOI: 10.4236/ojped.2013.34060

Cor-triatriatum dexter is an extremely rare congenital anomaly, in which right atrium is divided into 2 halves by a septum giving rise to 3 atrial chambers. We report here a case of cor-triatriatum dexter who presented at 3 days of life with tachypnea and did not respond to antibiotics. Echocardiography revealed ostium secundum atrial septal defect (ASD) with right to left flow, intact interventricular septum (IVS), severe tricuspid regurgitation with pulmonary arterial hypertension and a membranous structure dividing right atrium into 2 halves with good biventricular function. The patient improved with sildenafil and anti-failure medication. This case of cor-triatriatum dexter presenting with pulmonary hypertension, tricuspid regurgitation and ASD added to the new spectrum of cor-triatriatum dexter.

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