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Search Results: 1 - 10 of 582 matches for " Naveen Bobbili "
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The Antibody Response of Pregnant Cameroonian Women to VAR2CSA ID1-ID2a, a Small Recombinant Protein Containing the CSA-Binding Site
Anna Babakhanyan, Rose G. F. Leke, Ali Salanti, Naveen Bobbili, Philomina Gwanmesia, Robert J. I. Leke, Isabella A. Quakyi, John J. Chen, Diane Wallace Taylor
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0088173
Abstract: In pregnant women, Plasmodium falciparum-infected erythrocytes expressing the VAR2CSA antigen bind to chondroitin sulfate A in the placenta causing placental malaria. The binding site of VAR2CSA is present in the ID1-ID2a region. This study sought to determine if pregnant Cameroonian women naturally acquire antibodies to ID1-ID2a and if antibodies to ID1-ID2a correlate with absence of placental malaria at delivery. Antibody levels to full-length VAR2CSA and ID1-ID2a were measured in plasma samples from 745 pregnant Cameroonian women, 144 Cameroonian men, and 66 US subjects. IgM levels and IgG avidity to ID1-ID2a were also determined. As expected, antibodies to ID1-ID2a were absent in US controls. Although pregnant Cameroonian women developed increasing levels of antibodies to full-length VAR2CSA during pregnancy, no increase in either IgM or IgG to ID1-ID2a was observed. Surprisingly, no differences in antibody levels to ID1-ID2a were detected between Cameroonian men and pregnant women. For example, in rural settings only 8–9% of males had antibodies to full-length VAR2CSA, but 90–96% had antibodies to ID1-ID2a. In addition, no significant difference in the avidity of IgG to ID1-ID2a was found between pregnant women and Cameroonian men, and no correlation between antibody levels at delivery and absence of placental malaria was found. Thus, the response to ID1-ID2a was not pregnancy specific, but predominantly against cross-reactivity epitopes, which may have been induced by other PfEMP1 antigens, malarial antigens, or microbes. Currently, ID1-ID2a is a leading vaccine candidate, since it binds to the CSA with the same affinity as the full-length molecule and elicits binding-inhibitory antibodies in animals. Further studies are needed to determine if the presence of naturally acquired cross-reactive antibodies in women living in malaria endemic countries will alter the response to ID1-ID2a following vaccination with ID1-ID2a.
Microscopic Observation of Nuclear Track Pores in Polymeric Membranes  [PDF]
Naveen K. Acharya
Engineering (ENG) , 2011, DOI: 10.4236/eng.2011.36076
Abstract: Nuclear track pores were develop and observed in polycarbonate and LR-115 membranes. The polymer membranes were irradiated by swift heavy ions (SHI) and etched chemically. The stopping range of heavy ion is larger than the thickness of the membrane. The fluence of ions was changes from 103 to 107 ions-cm-2. The etching time was increased till pore size reaches up to micron range. The etching conditions were set to develop the porous tracks. The tracks are revealed under optical microscope as the size reaches up to micron or sub-micron size. The size was measured using standard electron diffraction grid. Results show that the porous tracks having average size of 2.4 micron can be developed in polycarbonate, while 5 - 10 micron porous tracks can be developed in LR-115.
Video Based Vehicle Detection and its Application in Intelligent Transportation Systems  [PDF]
Naveen Chintalacheruvu, Venkatesan Muthukumar
Journal of Transportation Technologies (JTTs) , 2012, DOI: 10.4236/jtts.2012.24033
Abstract: Video based vehicle detection technology is an integral part of Intelligent Transportation System (ITS), due to its non-intrusiveness and comprehensive vehicle behavior data collection capabilities. This paper proposes an efficient video based vehicle detection system based on Harris-Stephen corner detector algorithm. The algorithm was used to develop a stand alone vehicle detection and tracking system that determines vehicle counts and speeds at arterial roadways and freeways. The proposed video based vehicle detection system was developed to eliminate the need of complex calibration, robustness to contrasts variations, and better performance with low resolutions videos. The algorithm performance for accuracy in vehicle counts and speed was evaluated. The performance of the proposed system is equivalent or better compared to a commercial vehicle detection system. Using the developed vehicle detection and tracking system an advance warning intelligent transportation system was designed and implemented to alert commuters in advance of speed reductions and congestions at work zones and special events. The effectiveness of the advance warning system was evaluated and the impact discussed.
Minor modifications in obtainable Arabidopsis floral dip method enhances transformation efficiency and production of homozygous transgenic lines harboring a single copy of transgene  [PDF]
Priyanka Das, Naveen Chandra Joshi
Advances in Bioscience and Biotechnology (ABB) , 2011, DOI: 10.4236/abb.2011.22010
Abstract: Many researchers have developed various methods for in-planta or floral dip transformation of Arabidopsis thaliana, one of the simple protocol and widely used to produce transgenic Arabidopsis. As the efficiency and ease of getting a transformant is very much time consuming effort and less number of the transformants people get, we have developed a little modified transformation protocol to avoid the disparities. Four types of inoculums (inoculum1, inoculum2, inoculum3 and inoculum4) were used to check the transformation efficiency out of which Inoculum3 showed the highest rate of transformation among the four types. 0.07% Twin-20 also acts in same manner as silwet L-77 to increase the rate of transformation efficiency and glucose instead of sucrose can be used in inoculum to transform Arabidopsis. After vacuum infiltration keeping the Agrobacterium infected plants for 7-8 hrs horizontally in low light at 280C temperature condition, considered best to get an increased number of transformed seeds. Modified protocol produced ~12-14% increase in transformants. Selection pots (kanamycin supplemented soil filled pots) in place of selection plates (Kanamycin supplemented Murashige and Skoog agar plates) proved beneficial as no MS medium and no aseptic condition is required for selection of transformed plants. This increase in transformation efficiency consequently increased the percentage of homozygous and single copied stable transgenic lines.
Charged Lepton Flavour Violation in Littlest Higgs model with T-parity
Gaur, Naveen
High Energy Physics - Phenomenology , 2007, DOI: 10.1063/1.2898987
Abstract: The Little Higgs model with T-parity (LHT) belongs to the non-minimal flavour violating model. This model has new sources of flavour and CP violation both in quark and leptonic sectors. These new sources of flavour violation originates by the interaction of Standard Model (SM) fermions with heavy gauge bosons and heavy (or mirror) fermions. In this work we will present the impact of the new flavour structure of T-parity models on flavour violations in leptonic sector.
Validity of Running in Gait Biometrics
Naveen Rohila
International Journal of Electrical, Electronics and Computer Systems (IJEECS) , 2012,
Abstract: Due to increasing crime rate, necessity of visual surveillance and monitoring applications is increasing day by day. This paper describes the validity of running gait biometrics by establishing the relation between normal walking and running using Fourier Analysis and Phase Modulating Signals. Static and Dynamic features of each person are calculated for running and walking both. Experiments have been done at Govt. Polytechnic for Women, Faridabad in real world conditions. 77 persons participated in normal walking experiments and 15 persons from these participated in running experiments. The experimental results show that running of each person is unique and can be effectively used for recognition like normal walking.
Distributed Routing Simulation for Generic Network-on-Chip Topologies
Naveen Choudhary
International Journal of Engineering and Advanced Technology , 2011,
Abstract: Networks-on-Chip (NoC) is recently proposed as analternative to the on-chip bus to meet the increasing requirementof complex communication needs in Systems-on-Chip (SoC).Most researchers advocate the use of traditional regular networkslike meshes as architectural templates which gained a highpopularity in general-purpose parallel computing. However, mostSoC platforms are special-purpose tailored to the domain-specificrequirements of their application. They are usually built from alarge diversity of heterogeneous components which communicatein a very specific, mostly irregular way. In such systems the sizeand nature of cores may vary quite widely making the topologyirregular. Moreover regular topologies can become irregular dueto faults in links and switches. In such scenario topology agnosticrouting algorithms are generally required. In this paper, we haveanalyzed the performance and applicability distributed table basedrouting for irregular NoC on an Network-on-Chip simulationframework.
Deadlock Free Routing in Irregular Interconnection Networks for Complex SoCs
Naveen Choudhary
International Journal of Engineering and Advanced Technology , 2011,
Abstract: Networks-on-Chip (NoC) is recently proposed as an alternative communication infrastructure/Interconnection Network for address the high communication demands of the complex futuristic SoCs. Most researchers advocate the use of traditional regular networks like meshes as architectural templates which gained a high popularity in general-purpose parallel computing. However, most SoC platforms are special-purpose tailored to the domain-specific requirements of their application. They are usually built from a large diversity of heterogeneous components which communicate in a very specific, mostly irregular way. In such systems the size and nature of cores may vary quite widely making the topology irregular. Moreover regular topologies can become irregular due to faults in links and switches. In such scenario topology agnostic routing algorithms are generally required. In this paper, a survey of various deadlock free table based routing function is presented. The paper presents survey of deadlock free routing function with and without the availability of virtual layers
Indian Streams Research Journal , 2012,
Abstract: 'Choupal' in villages is a powerful source of entertainment and information. It is a wonderful gift of Indian culture. Today, in the era of digital technology, discussion, debate, constant flow of information, new ocean of knowledge and every common man has got a powerful medium to express his ideas and opinions which is known as Social Media. Social Media is such a digital platform which, through technical medium, providing important opportunity to people for knowledge-creation, participation and sharing knowledge and this social media is playing a role of such a 'Virtual Global Community Hall' whose boundaries are unlimited. The access of The Virtual Digital Hall is not limited to a particular region rather to every human being who in a way or other using internet. Global village is now converting into a Virtual Global Community Hall, a community hall where people may not be present physically but connected to every sphere of the world with the help of 'Key Board' and 'Computer Monitor'. In seconds, information can be transmitted from one corner of the world to other and we can make the world aware of our ideas. Mean to say that we can share our ideas without any hesitation, discuss the issues with people, can discuss socio-state problems for solution on Virtual Global Community Hall. Social Media began to connect friends; today it has connected the whole in a friendly manner. Social Media has opened the doors to the world for social change and is accessible to every corner of the world. Social Media has opened the door for the social change and Social Media has emerged as a powerful medium of social change worldwide.
Bridging the Digital Divide: Gyandoot—The Model for Community Networks [book review]
Naveen Prakash
Information Technologies and International Development , 2003,
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