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study was conducted to evaluate the physiological quality of forage seeds after
passage through the gastrointestinal tract of cattle, as well as the emergence
of seedlings derived from these seeds. Three Fabaceae species were used: tropical kudzu, leucaena and calopo.
One hundred grams of seeds of each species were offered, separately, to five
bovines. After the start of the dispersion, the faeces of the animals were
collected every 6 hours, in a total of 72 hours, being taken to the greenhouse
immediately after each collection. The study evaluated the total number of
seedlings in the stool, the lengths of roots and aerial parts, as well as the
natural and dry seedling weight thirty days after the disposal of the faeces in
the greenhouse. The experimental design consisted of randomized blocks, with
twelve treatments (sampling periods) and five replications (cattle). The best
performance for the total number of seedlings in the faeces of cattle was
observed in the kudzu species. The length of the root, length of the aerial
part and dry matter seedling weight was observed in the leucaena species,
followed by kudzu. The calopo showed low results for all variables due to the
high degradation of the seeds.
Cancer is a leading cause of death
worldwide, and is estimated to be the cause of 13.1 million deaths in 2030.
Breast cancer is the second cancer in the global mortality ranking, considering
both sexes. Due to the burden of breast cancer worldwide, this paper aims to
present an overview of the main R&D efforts focusing on breast cancer
treatment. Patents were retrieved from the Derwent Innovations Index?,
which has a specific code for pharmaceuticals related to breast cancer. A total
of 423 patent documents filed in recent years were identified, of which 126 are
exclusively for breast cancer, 169 for breast cancer and other cancers, and 128 are inventions related to the treatment of cancer and other diseases. The patent documents were
classified into two large groups, the first of which had a predominance of
claims for antibodies, proteins and polypeptides for use in medication
production, while the second focuses on gene therapy, nucleotides and RNA. The country with
the majority of priority
patent applications was found to be the United States, followed by China and Japan.