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Search Results: 1 - 10 of 332 matches for " Naim Haliti "
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The antibiotic utilization at the university dentistry clinical center of Kosovo  [PDF]
Fehim Haliti, Naim Haliti, Ferit Ko?ani, Agim Begzati, Fatmir Dragidella, Luljeta Ferizi, Lumnije Krasniqi, Dafina Doberdoli, Shqiprim Bajrami, Shaip Krasniqi
Open Journal of Stomatology (OJST) , 2013, DOI: 10.4236/ojst.2013.39080

Antibiotic drugs are a very important drug group considering their frequent use, safety profile and their impact on bacterial resistance induction. Aim: To investigate the utilization of antibiotic drugs at the University Dentistry Clinical Center of Kosovo (UDCCK). Methodology: Retrospective and descriptive study. Patient records were used as a data source collected for a period of 3 months. The total number of registered outpatients in the UDCCK was 1117 patients. The data analysis was performed using the WHO methodology and results were expressed in DDD per 1000 inhabitants per day. Results: The total prescription of antibiotics at UDCCK was 7.18 DDD/ 1000 inhabitants/day. Antibiotics were prescribed for 86 or 7.70% of patients. The most commonly prescribed antibiotic was Amoxicillin with clavulonic acid 3.12 (43.45%) DDD, followed by Metronidazole 2.31 DDD and Amoxicillin 1.25 DDD. Erythromycin and Cefalexin were prescribed evidently less compared to other antibiotics (0.38 and 0.12 DDD/1000 inhabitant/day, respectively). Conclusions: The quantitative analysis showed no rationality of prescription of antibiotics in UDCCK. Generally, the use of antibiotics in both departments of UDCCK is higher compared to other countries. We recommend the implementation of restrictive prescription standards for antibiotics.

The Rise and Fall of the Hydrophobic Effect in Protein Folding and Protein-Protein Association, and Molecular Recognition  [PDF]
Arieh Ben-Naim
Open Journal of Biophysics (OJBIPHY) , 2011, DOI: 10.4236/ojbiphy.2011.11001
Abstract: In the beginning everything was explained in Biochemistry in terms of hydrogen-bonds (HB). Then, the devastating blow, known as the HB-inventory argument came; hydrogen bonding with water molecules compete with intramolecular hydrogen-bonds. As a result, the HBs paradigm fell from grace. The void created was immediately filled by Kauzmann’s idea of hydrophobic (HφO) effect which reigned supreme in biochemical literature for over 50 years (1960-2010). Cracks in the HB-inventory argument on one hand, and doubts about the adequacy of Kauzmann’s model for the HφO effect, have led to a comeback of the HBs, along with a host of new hydrophilic (HφI) effects. The HφO effects lost much of its power - which it never really had - in explaining protein folding and protein-protein association. Instead, the more powerful and richer repertoire of HφI effects took over the reins. The interactions also offered simple and straightforward answers to the problems of protein folding, and protein-protein association.
Some No Longer Unknowns in Science  [PDF]
Arieh Ben-Naim
Open Journal of Biophysics (OJBIPHY) , 2012, DOI: 10.4236/ojbiphy.2012.21001
Abstract: Three out of 125 “big questions of science”, can now be claimed to have been answered. All of these questions involve water; its structure, its role in protein folding and its role in protein-protein association.
Levinthal’s Paradox Revisited, and Dismissed  [PDF]
Arieh Ben-Naim
Open Journal of Biophysics (OJBIPHY) , 2012, DOI: 10.4236/ojbiphy.2012.22004
Abstract: This article is concerned with the so-called Levinthal’s paradox. It will be argued that many have sought a “solution” to Levinthal’s paradox, where in fact, the “solution” already appeared in Levinthal’s original articles. Most of the subsequent suggested “solutions” were inadequate solutions to a non-paradox. It is shown that the discovery of strong hydrophilic forces not only dismisses the Levintal paradox, but also provides a solution to the general problem of protein folding. A simple model based on the Markov process is presented to demonstrate how a strong biased-force can dramatically reduce the number of steps required to reach the stable native 3-D structure of the protein.
Examining the M67 Classification as an Open Cluster  [PDF]
Shimmon Naim, Evgeny Griv
International Journal of Astronomy and Astrophysics (IJAA) , 2012, DOI: 10.4236/ijaa.2012.23020
Abstract: The cluster M67 (= NGC 2682) in Cancer is a rich stellar cluster, usually classified as an open cluster. Using our own observations with the 0.4 m telescope, we show that M67 is a tight group of about 1200 stars. The actual radius of the cluster is about 3.1 pc and the average mass of a star in the system is about . We also show that the ratio of the mean kinetic energy of the cluster to its mean gravitational potential energy , while the value predicted by the virial theorem is equal to . So the system is a gravitationally bound. This value of is considered as an evidence of quasi-stability of the cluster and allows us to use the Chandrasekhar-Spitzer relaxation time for M67 Myr as a characteristic dynamical relaxation time of the system. As the cluster is almost twice older its half-life time , it is argued that M67 was in the past (about 4 Gyr ago, close to its forma-tion) a relatively small ( stars) globular cluster, but got “open cluster” shape due to the dynamical evapora-tion of the majority of its stars.
Theory of cold denaturation of proteins  [PDF]
Arieh Ben-Naim
Advances in Biological Chemistry (ABC) , 2013, DOI: 10.4236/abc.2013.31005

A new approach to the problem of cold denaturation is presented. It is based on solvent-induced effects operating on hydrophilic groups along the protein. These effects are stronger than the corresponding hydrophobic effects, and they operate on the hydrophilic groups which are plentiful than hydrophobic groups. It is shown that both heat and cold denaturation can be explained by these hydrophilic effects.

Comment on a Paper: “Ben-Naim’s ‘Pitfalls’: Don Quixote’s Windmill”, by Y. Fang, Open Journal of Biophysics, 2013, 3, 13-21  [PDF]
Arieh Ben-Naim
Open Journal of Biophysics (OJBIPHY) , 2013, DOI: 10.4236/ojbiphy.2013.34032

This article is a response to Fangs article which criticizes statements never made by Ben-Naim and never appeared in the literature.

The cleaning efficiency of the root canal after different instrumentation technique and irrigation protocol: A SEM analysis  [PDF]
Ferit Ko?ani, Blerim Kamberi, Edmond Dragusha, Shefqet Mrasori, Fehim Haliti
Open Journal of Stomatology (OJST) , 2012, DOI: 10.4236/ojst.2012.22013
Abstract: Aim: The objective of this study was to evaluate the effectiveness of manual and ultrasonic instrumentation with varying irrigation protocols on removal of the smear layer from root canal walls. Methods: Forty extracted single rooted human teeth stored in 0.5% saline were used. Periodontal soft tissues were removed followed by crown separation at the CEJ. All the teeth were randomly divided into two groups. Manually Instrumented Group 1 was irrigated with 5.25% NaOCl and 17% EDTA alternately, same as Ultrasonically Instrumented Group 2. The controls for both groups were irrigated with saline solution. Results: Ultrasonic instrumentation and the combined use of two different solutions (5.25% NaOCl and 17% EDTA) yielded better results on smear removal. Conclusions: Irrigation with 17% EDTA followed by 5.25% NaOCl was successful in complete removal of smear layer on cervical and middle thirds of the root canals. Ultrasonic instrumentation was slightly more successful on the apical one third of the root canals.
Ozone Therapy in a Patient with Diabetic Foot Ulcerations and a Decision for Amputation  [PDF]
Saltuk Aytacoglu, Barlas Naim Aytacoglu
Case Reports in Clinical Medicine (CRCM) , 2019, DOI: 10.4236/crcm.2019.82005
Abstract: Background: Diabetic foot together with open wounds in distal type peripheral arterial disease constitutes a challenge in therapeutic planning. Ozone therapy may unveil new horizons in management. Case Report: A 67-year-old woman with diabetes mellitus was applied with open wounds at the bottom of her foot with purulent discharge, with a decision for above ankle amputation. She had had numerous interventions for her wounds including metatarsal amputations due to osteomyelitis and had been on an intense treatment including antibiotics, insulin, antihypertensives and antiaggregants. Angiogram revealed diffuse peripheral arterial disease in lower extremities. All medication but antihypertensives was stopped. She received major medical ozone application as 2000 gamma/session i.v. for 2 weeks, external ozone sac application starting from 60 and dropping to 30 gamma/session for 3 weeks and ozone insuflation 40 gamma/session for 10 sessions. Her purulent discharge ceased after the third session and the atonic debris of the wounds exfoliated, the wounds healed from the base towards the surface of the skin. She was then put on cilostazol and clopidogrel therapy. Conclusion: By being one of the known strongest bactericide, virucide, and fungicide elements, medical ozone therapy stimulates and upregulates the antioxidant system of the body with its hormesis effects. After the cessation of all circulatory system supporting medication (as their interaction with ozone is not clear yet), appropriate ozone therapy may bring new horizons for patients when all classically known methods of treatment have been completed, before assigning the patients for amputation.
Naim Salki?
Human : Research in Rehabilitation , 2013,
Abstract: Bilingualism of a deaf child implies concurrent cognition and usage of sign language, as community language and oral-voice language as language of greater community in which deaf persons live. Today, most authors consider that deaf persons should know both of these languages and that deaf persons need to be educated in both languages, because of their general communication and complete psycho-social development. Through research on sample of 80 deaf examinees, we affirmed the kind of relation that deaf persons have towards bi-lingualism, bilingual way of education and communication. The research results have shown that bilingualism and bilingual way of education and communication is acceptable to deaf persons and that there is no statisti-cally significant difference between the sub-samples of examinees.
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