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Search Results: 1 - 3 of 3 matches for " Nahom Iyob "
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Triphenylmethanol and Tris(2-(hydroxymethyl)phenol) Derivatives: Synthesis and Application as Indicators for Acid-Base Volumetric Titration  [PDF]
Ryan Beni, William Boadi, Jawzah Alnakhli, Samiyah Alhamed, Tiffany Robinson, Melanie Mootry, Nahom Iyob, Jamill Jackson, Natalie Spicer, Anterrial Harris, Ibrahim Bamidad, Renner Antwi, Shania Richardson, Tralynn Williams
Journal of Analytical Sciences, Methods and Instrumentation (JASMI) , 2019, DOI: 10.4236/jasmi.2019.92002
Abstract:
Polyphenols are naturally occurring compounds found largely in fruits, vegetables, cereals and beverages. Currently, there is much interest in the potential health benefits of dietary plant polyphenols as antioxidants. The effect of polyphenols on human cancer cells is most often protective and induces a reduction in the number of tumors or rate of growth. During our course of study on anticancer prodrugs, twelve triphenylmethanol and one tris(2-(hydroxymethyl) phenol derivatives were synthesized as a carrier of several drugs with optimized lipophilicity. Besides application of these compounds as a foundation for anticancer drug delivery systems, these compounds were evaluated as indicators for the acid-base volumetric titration of a standard solution of hydrochloric acid with a standard solution of sodium hydroxide. The experiments indicated a moderate-to-sharp color transition of the solutions near the neutralization point for most indicators. These indicators may have potential applications for acid-base titrations in a narrow range.
Investigation of the Physico-Chemical Standards of the Ground Waters around Mai-Bella Area in Asmara  [PDF]
Goitom Kfle, Mussie Sium, Arumugam Manohar, Semere Debretsion, Aron Tesfamariam, Nahom Tesfalem, Abel Okbaselasie, Kibrom Tesfay
Journal of Geoscience and Environment Protection (GEP) , 2019, DOI: 10.4236/gep.2019.79011
Abstract: There are many possible sources of ground water contamination and may include wastes from industrial chemical production, domestic wastewater and pesticide run off from agricultural lands. The groundwater is thus susceptible to chemical, physical and/or microbiological contamination and ultimately becomes a cause for diverse diseases borne from the contaminated water. It has been a common practice to cultivate vegetables, crops and animal feed grasses around Asmara using sewage and industrial effluents and there are likelihoods that contaminants in the wastewater used for irrigation would infiltrate to the nearby wells. It is believed that the groundwater around the wastewater irrigated area is not safe for domestic and agricultural applications. Thus, this study was conducted to evaluate the quality of the groundwater in order to safeguard the public health treats caused by using this water. Samples were collected from five locations around Mai-Bella and thus different physico-chemical parameters were investigated. The pH of the samples was measured by pH metric method; electrical conductivity (EC) and salinity by using conductometric method. Hardness was estimated by EDTA method; total alkalinity (TA) and bicarbonate concentrations by titrimetric methods. Chloride concentration was analyzed by titration against mercurial nitrate. Na and K were determined using flame photometric method. Fe, Mn, nitrate, nitrite, sulphates and ammonia were determined using spectrophotometric method. Chemical Oxygen Demand (COD) was determined using photometric method. Moreover, the concentrations of trace, major and heavy metals were analysed using Inductively Coupled Plasma Optical Emission Spectrophotometer (ICP-OES). The suitability of the groundwater for domestic and irrigation purposes was examined using WHO and FAO standards. Most of the physico-chemical parameters, except the temperature, pH, COD, Al, Cd, Cr, Cu and Zn, of the samples were found above the standard limits given by WHO. Similarly, the levels of toxic metals (Pb, As, Hg and Se) in all the water sources and Ni from two water sources were found above the permissible limit. Accordingly, the results signpost that most of the groundwater samples from the study sites are not suitable for drinking and irrigation purposes. Further studies related to the bacterial load would be appropriate to assess the health effects of all the water sources found around Mai-Bella.
VURD Syndrome in a Female
A. Zaccara,M. P. Pascali,A. Marciano,E. Carnevale,G. Salvatori,A. Dotta,A. Nahom,M. De Gennaro
Advances in Urology , 2011, DOI: 10.1155/2011/852928
Abstract: VURD syndrome has been repeatedly described as unilateral reflux into a nonfunctioning renal moiety. This syndrome is considered a pop-off mechanism dissipating pressure in lower urinary tract obstruction: it may be found in association with other protective mechanisms occurring in utero, such as ascites and/or urinomas, and has been exclusively described in male patients. A premature female baby with signs and symptoms of outflow obstruction underwent diagnostic workup revealing congenital urethral hypoplasia with unilateral reflux into a dysplastic kidney. Obstetrical history was positive for early onset, serologically negative ascites without cardiomegaly, which required serial aspirations. Reconstructive surgery was carried out with good results: ascites and VURD syndrome were both deemed to be perinatal protective mechanism against excess pressure in the urinary tract. Although rare, lower urinary tract obstruction in the female can lead to the same protective mechanisms seen in male fetuses/newborns. VURD syndrome and ascites should be interpreted as such and require perinatal specialist counselling. 1. Introduction Antenatal diagnosis of lower urinary tract obstruction has long been established: obstruction is usually associated with either posterior urethral valves or urethral atresia: as such, it is mostly seen in male fetuses [1]. Postnatal functional consequences of obstruction may consist of unilateral reflux and dysplasia, the so-called “VURD Syndrome” which is present in about 30% of patients with lower urinary tract obstruction. This syndrome was described in 1982 by Hoover and Duckett: a pop-off mechanism, dissipating high pressures generated by obstruction, was called upon to explain the association [2]. Fetal lower urinary tract obstruction in the female is quite rare and mostly includes prolapsing ureterocele and cloacal plate anomalies: the former may obstruct bladder outlet [3] whereas in the latter failure of urogenital membrane to involute will result in accumulation of drainage above the membrane and may result in hydrocolpos, urethral or ureteral obstruction, and hydronephrosis [4]. Antenatally, a spectrum of protective mechanisms may be exerted by the fetus to relieve pressure within the urinary tract: ascites (secondary to microscopic perforation in the posterior fornix or with extravasations at the caliceal fornix with escaping urine reaching perirenal space [5]), bladder rupture [6], and more importantly, perinephric urinoma [7]. However, there are no reports in the literature of VURD syndrome occurring in female fetuses
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