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Search Results: 1 - 10 of 479662 matches for " Myung-A Kim "
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Immediate impact of exercise on arterial stiffness in humans  [PDF]
Jae-Bin Seo, Woo-Young Chung, Sang-Hyun Kim, Myung-A Kim, Joo-Hee Zo
World Journal of Cardiovascular Diseases (WJCD) , 2013, DOI: 10.4236/wjcd.2013.31009

Background and objectives: Increased arterial stiffness is an accepted cardiovascular risk factor. Several studies have shown that regular exercise is associated with reduced arterial stiffness. However, the acute effect is not well known. The aim of this study was to evaluate the immediate impact of exercise on arterial stiffness measured by pulse wave velocity (PWV). Subjects and Methods: Data from 100 consecutive patients who underwent graded maximal aerobic exercise test and pulse wave velocity study due to chest pain were analyzed. Results: With respect to brachial-ankle pulse wave velocity (baPWV), it decreased after the exercise test (before vs. after; 1420 ± 260 vs. 1358 ± 245, 1428 ± 255, vs. 1360 ±239 cm/sec; left and right, respectively). Upper extremity systolic blood pressure did not change from baseline. However, upper extremity diastolic blood pressure increased slightly. In addition, lower extremity blood pressure decreased in both systolic and diastolic phases. In both normotensives and hypertensives, baPWV decreased after exercise test. Conclusion: Exercise immediately decreases arterial stiffness.

A case of successful survival from ventricular free wall micro-rupture without surgery  [PDF]
Jae-Bin Seo, Ki-Hyun Jeon, Jin-Hyun Park, Sang-Hyun Kim, Joo-Hee Zo, Myung-A Kim, Woo-Young Chung
World Journal of Cardiovascular Diseases (WJCD) , 2013, DOI: 10.4236/wjcd.2013.32029

We report a case of successful survival from ventricular free wall rupture without surgery, which was not overt rupture but micro-rupture. The patient was diagnosed with acute myocardial infarction (AMI) and underwent primary percutaneous coronary intervention (PCI). Myocardial blood leakage could be detected on transthoracic echocardiography with intravenous infusion of contrast dye 3 days after PCI. This examination revealed that there was not overt perforation but diffuse fissure. Because of his critical condition, he was treated conservatively without surgery. Nevertheless, he survived eventually.

Inhibitory Effect of Nelumbo nucifera (Gaertn.) on the Development of Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice
Rajendra Karki,Myung-A Jung,Keuk-Jun Kim,Dong-Wook Kim
Evidence-Based Complementary and Alternative Medicine , 2012, DOI: 10.1155/2012/153568
Abstract: Atopic dermatitis (AD) is a chronic inflammatory skin disease which has a complex etiology that encompasses immunologic responses. The study was carried out to examine the effect of Nelumbo nucifera (Gaertn.) leaf (NL) on the AD-like skin lesion induced by repeated epicutaneous application of 2,4-dinitrochlorobenzene (DNCB) on the dorsal skin of NC/Nga mice. Three different doses of NL (5, 25, and 50 mg/mice/day) were administered orally from the day of sensitization with DNCB for 4 weeks. The efficacy of NL was judged by histopathological examination, blood IgE level, measurement of transepidermal water loss (TEWL), scratching behavior, and skin severity score. NL resulted in the suppression of clinical severity score, TEWL, scratching behavior, and blood IgE level. Histopathologic analyses revealed that thickening of the epidermis and mast cell degranulation was significantly reduced in NL group. These results suggest that NL may be a useful natural resource for the management of AD.
The association between arterial stiffness and left ventricular filling pressure in an apparently healthy Korean population
Hack-Lyoung Kim, Moon-Sun Im, Jae-Bin Seo, Woo-Young Chung, Sang-Hyun Kim, Myung-A Kim, Joo-Hee Zo
Cardiovascular Ultrasound , 2013, DOI: 10.1186/1476-7120-11-2
Abstract: A total of 115 healthy subjects without known cardiovascular risk factors or overt heart disease who underwent both transthoracic echocardiography and brachial-ankle pulse wave velocity (baPWV) measurement at the same day during their routine check-ups were analyzed.The mean age of study subjects was 52.8 ± 8.4 years, and 78 (67.8%) were men. The mean baPWV value was 1,325 ± 185 cm/s. Study subjects were divided into 3 groups according to E/E’ value: subjects with E/E’ < 8, 8–12.9 and E/E’ ≥ 13. As E/E’ increased, baPWV value increased gradually: baPWV in subjects with E/E’ < 8, E/E’ 8–12.9 and E/E’ ≥ 13, were 1,261 ± 163, 1,345 ± 169, 1,569 ± 232 cm/s, respectively (p < 0.001). In multiple linear regression analyses, baPWV was significantly associated with E/E’ (β = 0.371, p < 0.001) after controlling confounders including age, sex and body mass index. In receiver-operating characteristic (ROC) curve analysis, the sensitivity and specificity for detection of E/E’ ≥ 10 were 78.6% and 59.8%, respectively with mean baPWV of 1,282 cm/s as the cut off value. The discriminatory capacity for predicting E/E’ ≥ 10 was improved from an area under the ROC curve of 0.646 with age alone to 0.734 when baPWV was added (p < 0.001).There is a significant association between baPWV and E/E’ in an apparently healthy Korean population. BaPWV is useful as a simple and non-invasive method for early detection of increased LV filling pressure among these people.Stiffened artery increases pulse pressure leading to left ventricular hypertrophy and coronary artery disease [1]. Arterial stiffness has been reported to be associated with cardiovascular morbidity and mortality [2,3].There are several methods to estimate arterial stiffness. Among them, pulse wave velocity (PWV) is generally accepted as the most simple, non-invasive and validated indicator of arterial stiffness [4,5]. Recently, the brachial-ankle PWV (baPWV) measurement, which is easy to perform, has become available in clinical pr
The prevention of contrast induced nephropathy by sarpogrelate in patients with chronic kidney disease: a study protocol for a prospective randomized controlled clinical trial
Kyungil Park, Woo-Young Chung, Jae-Bin Seo, Sang-Hyun Kim, Joo-Hee Zo, Myung-A Kim, Young-Bae Park
Trials , 2010, DOI: 10.1186/1745-6215-11-122
Abstract: The present study aims to investigate differences in occurrence of CIN after sarpogrelate premedication in patients with chronic kidney disease (CKD). 268 participants, aged 20-85 years with a clinical diagnosis of CKD will be recruited. They will be randomly allocated to one of two conditions: (i) routine treatment without sarpogrelate, and (ii) routine treatment with sarpogrelate (a fixed-flexible dose of 300 mg/day). The primary outcome is the occurrence of CIN during 4 weeks after receiving contrast agent.As of May 2010, there were no registered trials evaluating the therapeutic potentials of sarpogrelate in preventing for CIN. If sarpogrelate decreases the worsening of renal function and occurrence of CIN, it will provide a safe, easy and inexpensive treatment option.NCT01165567Contrast-induced nephropathy (CIN) is a common form of hospital-acquired acute renal failure (ARF) after coronary angiography (CAG) and percutaneous coronary intervention (PCI) and is associated with prolonged hospitalization and adverse clinical outcomes [1,2]. Patients undergoing PCI have a higher mortality rate if the nephropathy develops [3]. Although its incidence is low in patients with normal renal function, it can be much higher in those with renal insufficiency at baseline [4,5]. Adequate prophylaxis is needed to reduce the higher morbidity and mortality associated with CIN in high-risk patients. A variety of therapeutic interventions, including saline hydration, diuretics, mannitol, calcium channel antagonists, theophylline, endothelin receptor antagonists, and dopamine, have been used in an attempt to prevent CIN [6-9]. Hydration with normal saline solution is the most widely accepted preventive intervention [9,10]. But the nephropathy occurred in 20~30% who received the recommend treatment [11,12], it means current treatments are not enough and the optimal strategy to prevent CIN has not been established.Although the pathogenesis of this condition is not fully understood, it
Impact of acute exercise on brachial artery flow-mediated dilatation in young healthy people
In-Chang Hwang, Kyung-Hee Kim, Won-Suk Choi, Hyun-Jin Kim, Moon-Sun Im, Yong-Jin Kim, Sang-Hyun Kim, Myung-A Kim, Dae-Won Sohn, Joo-Hee Zo
Cardiovascular Ultrasound , 2012, DOI: 10.1186/1476-7120-10-39
Abstract: Eighty-six young healthy volunteers were prospectively enrolled from January 2011 to December 2011. The subjects completed FMD tests at rest and immediately after treadmill exercise test. Primary outcome was the impact of acute exercise on FMD, measured by the difference of FMD before and after exercise. Secondary outcomes were the relationship of gender and exercise habit with FMD.Seventy-four subjects who met the eligibility criteria were included for analysis. Thirty-five (47.3%) were male, and the mean age was 22.7±2.7 years. FMD was reduced after exercise (8.98±4.69 to 7.51±4.03%; P=0.017) and the reduction was found in female group (10.36±5.26 to 7.62±3.71%; P=0.002) but not in male group. Post-exercise FMD was significantly impaired in subjects who did not exercise regularly (6.92±3.13% versus 8.95±5.33%; P=0.003). The decrease of FMD after exercise was greater in female group (?2.75±5.28% versus 0.27±3.24%; P=0.003) and was associated with exercise habit (β=2.532; P=0.027).In healthy young subjects, FMD was reduced after a bout of acute exercise. The impact of acute exercise showed significant differences according to gender and exercise habit. FMD impairment after acute exercise was observed in females and subjects without regular exercise.Endothelial dysfunction is an important factor in the development of atherosclerosis, hypertension, and coronary artery disease (CAD) [1-4]. Impaired endothelial function is observed in subjects with risk factors for atherosclerosis and in patients with essential hypertension [2,5,6]. Also it is an important predictor of long-term cardiovascular events [7,8].There are several methods to assess endothelial dysfunction and flow-mediated dilatation (FMD) is the most widely used non-invasive method to assess the endothelial function, reflecting the endothelial nitric oxide (NO) dependent vasodilation in response to occlusion-induced reactive hyperemia [5,9]. As FMD is non-invasive and reliable, allows repeated measurements [1
The Aesthetic Turn in Everyday Life in Korea  [PDF]
Kwang Myung Kim
Open Journal of Philosophy (OJPP) , 2013, DOI: 10.4236/ojpp.2013.33054
Abstract: We are living in the transitional age from the rational, analytical, and scientific to the cultural, sensitive, and aesthetic. The aesthetics of everyday life lies at the center of this age. There is no boundary between art and life in contemporary art. Almost all the contents and objects of everyday life became a work of art in the condition of searching for the aesthetic. Since aesthetic theory was shifted from the artist-centered or a work of art-centered to the audience, spectator or beholder-centered, art and everyday life were more closely related to each other. So aesthetic attention or attitude is not specific to art, but pervasive broadly in everyday life. We can embrace the aesthetic concerns in everything we make and use every day. In the long tradition of Korean art, it can be seen that aesthetic consciousness is steeped in day-to-day life as well as the arts. I want to consider the problems of everydayness, Korean aesthetic consciousness in daily life, and contemplation in the aesthetic consciousness. Korean art was characterized by its “lack of refinement” and “nonchalance”. The characteristics of Korean art as the qualities of “technique without technique”, “Planning without plan”, “asymmetrical symmetry” have dominated the everyday consciousness of Korean people as well as Korean art. The extension of aesthetic emotion through experimentation shows us the change of aesthetic consciousness as a new possibility of interpretation. We stand in an urgent situation of the need for a new theory of art. It will be related to the future of aesthetics. For this reason, I think we have to consider the meaning of the aesthetic turn in everyday life.
Problems and Prospects of Geoaesthetics  [PDF]
Kwang Myung Kim
Open Journal of Philosophy (OJPP) , 2015, DOI: 10.4236/ojpp.2015.51001
Abstract: Geoaesthetics is the project of making aesthetic sense of nature through geological phenomena. The aesthetic appreciation of nature has recently become urgent because of the serious influence of the natural environment on human beings. The author’s geoaesthetical research is categorized into three problems: art in geology or geology in the arts as the close relationship between art and geology, geological cognition of nature and natural cognition in environmental aesthetics, and the geoaesthetical approach through works of art. Geologic forces and processes have become significant materials for aesthetic sensations. Based on the geoaesthetic perspective, the author explores the ultimate purpose of art as a return to natural order. It seems partly to be related to the ontological problem of art. Here we can feel earthly dynamics, universal calmness, and the contemplative atmosphere simultaneously.
Lemierre Syndrome – The forgotten disease Síndrome de Lemierre – A doen a esquecida
Carlos Eduardo Marcello,Elizabeth In Myung Kim,Luciana Andréa Avena Smeili,Leonardo Bianqui
Autopsy and Case Reports , 2011,
Abstract: Acute pharyngitis is among the most common causes of demand for emergency services. In general, they are benign, mostly of viral or bacterial etiology and evolve without complications with appropriate therapy. Rarely the infection extends deeply through the neck tissues generating serious suppurative complications. Herein is reported a case of a 20-year-old young woman who developed acute pharyngitis followed by left cervical bulging and cough with bloody sputum. Chest radiography showed bilateral pulmonary infiltrate which on thoracic computed tomography slices were represented by cavitary nodules measuring up to 33 mm universally distributed on both lungs, predominantly on peripheral location. Computed tomography of the neck with intravenous contrast showed extensive thrombosis of the left internal jugular vein, from the base of the skull to the distal third of the neck. Diagnosis of Lemierre Syndrome was made and the patient was treated with a favorable outcome. As faringites agudas est o entre as causas mais comuns de procura aos servi os de emergência. De maneira geral, s o doen as benignas, na sua grande maioria de etiologia viral ou bacteriana e cursam sem complica es quando instituída terapêutica apropriada. Raramente o processo infeccioso pode se estender para os planos profundos do pesco o e gerar complica es supurativas graves. Relatamos o caso de uma paciente de 20 anos que desenvolveu faringite aguda, logo seguida de abaulamento cervical à esquerda, além de tosse com laivos de sangue e infiltrados pulmonares bilaterais à radiografia do tórax - achado confirmado à tomografia de tórax que relevou parênquima pulmonar com nódulos cavitados medindo até 33 mm em lobos inferiores e superiores bilaterais, de localiza o periférica. A tomografia computadorizada do pesco o com contraste endovenoso mostrou trombose extensa da veia jugular interna esquerda, desde a base do cranio até o ter o distal do pesco o Através dos procedimentos de imagem o diagnóstico de Síndrome de Lemierre foi feito e a paciente foi tratada com sucesso.
How Safe Is Safe Enough? Radiation Risk for a Human Mission to Mars
Francis A. Cucinotta, Myung-Hee Y. Kim, Lori J. Chappell, Janice L. Huff
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0074988
Abstract: Astronauts on a mission to Mars would be exposed for up to 3 years to galactic cosmic rays (GCR) — made up of high-energy protons and high charge (Z) and energy (E) (HZE) nuclei. GCR exposure rate increases about three times as spacecraft venture out of Earth orbit into deep space where protection of the Earth's magnetosphere and solid body are lost. NASA's radiation standard limits astronaut exposures to a 3% risk of exposure induced death (REID) at the upper 95% confidence interval (CI) of the risk estimate. Fatal cancer risk has been considered the dominant risk for GCR, however recent epidemiological analysis of radiation risks for circulatory diseases allow for predictions of REID for circulatory diseases to be included with cancer risk predictions for space missions. Using NASA's models of risks and uncertainties, we predicted that central estimates for radiation induced mortality and morbidity could exceed 5% and 10% with upper 95% CI near 10% and 20%, respectively for a Mars mission. Additional risks to the central nervous system (CNS) and qualitative differences in the biological effects of GCR compared to terrestrial radiation may significantly increase these estimates, and will require new knowledge to evaluate.
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