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Search Results: 1 - 10 of 25341 matches for " Myeong Lee "
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Strategic Approach to the Globalization of Sasang Constitutional Medicine
Myeong Soo Lee
Evidence-Based Complementary and Alternative Medicine , 2011, DOI: 10.1093/ecam/nep202
Abstract: The workshop on “Strategic Approach to the Globalization of Sasang Constitutional Medicine (SCM)” was held in the Korea Institute of Oriental Medicine (KIOM) on September 18, 2009. This workshop was designed to discuss and brainstorm the strategic approach to the globalization of SCM, one of the unique systems in Korean Traditional Medicine, with three topics and an extensive panel discussion. Professor Edwin Cooper, Editor-in-Chief of eCAM, gave a commemorative lecture for publication of the second supplement of eCAM entitled “Sasang Constitutional Medicine as a Holistic Tailored Medicine”. The other two presenters suggested some practical methods for globalization of SCM on the basis of their experiences. After the three main presentations, there was a panel discussion session for further development of workshop topics, extended by five other external experts. They discussed the benefits, limitations and essentials for globalization of Korean Traditional Medicine, specifically SCM, from bench to bedside.
Response to Wiart, C. Lee et al., Inhibitory Effect and Mechanism of Antiproliferation of Isoatriplicolide Tiglate (PCAC) from Paulownia coreana. Molecules 2012, 17, 5945-5951: A Note Regarding Paulownia coreana. Molecules 2013, 18, 2587-2588.
Myeong-Sok Lee
Molecules , 2013, DOI: 10.3390/molecules18033041
Abstract: In a Comment recently published in Molecules [1], Prof. C. Wiart took issue with our identification of the plant species used in our work as Paulownia coreana. Although this name was assigned by H. Uyeki in 1925 [2], appears as such in handbooks of Korean flora [3], and examples of its use can be found in the recent literature [4–9], after reviewing the arguments and references presented in [1], we now recognize that this is no longer considered an accepted species name, and therefore we wish to revise our assignment to Pauwlonia tormentosa (Thunb.) Steud. We thank Prof. Wiart for bringing this fact to our attention and apologize to the readership of Molecules for any confusion caused by our previous classification of the species.
Vortex Dynamics in Selfdual Maxwell-Higgs Systems with Uniform Background Electric Charge Density
Ki-Myeong Lee
Physics , 1993, DOI: 10.1103/PhysRevD.49.4265
Abstract: We introduce selfdual Maxwell-Higgs systems with uniform background electric charge density and show that the selfdual equations satisfied by topological vortices can be reduced to the original Bogomol'nyi equations without any background. These vortices are shown to carry no spin but to feel the Magnus force due to the shielding charge carried by the Higgs field. We also study the dynamics of slowly moving vortices and show that the spin-statistics theorem holds to our vortices.
Generation and Control of Game Virtual Environment
Myeong Won Lee,Jae Moon Lee,

国际自动化与计算杂志 , 2007,
Abstract: In this paper,we present a framework for the generation and control of an Internet-based 3-dimensionai game virtual environment that allows a character to navigate through the environment.Our framework includes 3-dimensional terrain mesh data processing,a map editor,scene processing,collision processing,and waikthrough control.We also define an environment-specific semantic information editor,which can be applied using specific location obtained from the real world.Users can insert text information related to the characters real position in the real world during navigation in the game virtual environment.
Aspirin Has Antitumor Effects via Expression of Calpain Gene in Cervical Cancer Cells
Sang Koo Lee,Min Seon Park,Myeong Jin Nam
Journal of Oncology , 2008, DOI: 10.1155/2008/285374
Abstract: Aspirin and other nonsteroidal anti-inflammatory drugs show efficacy in the prevention of cancers. It is known that they can inhibit cyclooxygenases, and some studies have shown that they can induce apoptosis. Our objective in this study was to investigate the mechanism by which aspirin exerts its apoptosis effects in human cervical cancer HeLa cells. The effect of aspirin on the gene expression was studied by differential mRNA display RT-PCR. Among the isolated genes, mu-type calpain gene was upregulated by aspirin treatment. To examine whether calpain mediates the antitumor effects, HeLa cells were stably transfected with the mammalian expression vector pCR3.1 containing mu-type calpain cDNA (pCRCAL/HeLa), and tumor formations were measured in nude mice. When tumor burden was measured by day 49, HeLa cells and pCR/HeLa cells (vector control) produced tumors of 2126 mm3 and 1638 mm3, respectively, while pCRCAL/HeLa cells produced markedly smaller tumor of 434 mm3 in volume. The caspase-3 activity was markedly elevated in pCRCAL/HeLa cells. The increased activity levels of caspase-3 in pCRCAL/HeLa cells, in parallel with the decreased tumor formation, suggest a correlation between caspase-3 activity and calpain protein. Therefore, we conclude that aspirin-induced calpain mediates an antitumor effect via caspase-3 in cervical cancer cells.
Aromatherapy Massage Affects Menopausal Symptoms in Korean Climacteric Women: A Pilot-Controlled Clinical Trial
Myung-Haeng Hur,Yun Seok Yang,Myeong Soo Lee
Evidence-Based Complementary and Alternative Medicine , 2008, DOI: 10.1093/ecam/nem027
Abstract: This study investigated the effects of aromatherapy massage on menopausal symptoms in Korean climacteric women. Kupperman's menopausal index was used to compare an experimental group of 25 climacteric women with a wait-listed control group of 27 climacteric women. Aromatherapy was applied topically to subjects in the experimental group in the form of massage on the abdomen, back and arms using lavender, rose geranium, rose and jasmine in almond and primrose oils once a week for 8 weeks (eight times in total). The experimental group reported a significantly lower total menopausal index than wait-listed controls (P < 0.05). There were also significant intergroup differences in subcategories such as vasomotor, melancholia, arthralgia and myalgia (all P < 0.05). These findings suggest that aromatherapy massage may be an effective treatment of menopausal symptoms such as hot flushes, depression and pain in climacteric women. However, it could not be verified whether the positive effects were from the aromatherapy, the massage or both. Further rigorous studies should be done with more objective measures.
Randomized Clinical Trials on Acupuncture in Korean Literature: A Systematic Review
Jae Cheol Kong,Myeong Soo Lee,Byung-Cheul Shin
Evidence-Based Complementary and Alternative Medicine , 2009, DOI: 10.1093/ecam/nem130
Abstract: The aim of this systematic review was to summarize randomized clinical trials (RCTs) assessing the effectiveness of acupuncture as published in Korean literature. Systematic searches were conducted on eight Korean medical databases. Manual searches were also conducted through eight major Korean medical journals. The methodological quality was assessed using a Jadad score. Studies evaluating needle acupuncture or auricular acupuncture (AA) with or without electrical stimulation were considered if they were sham or placebo-controlled or controlled against a comparative intervention. We also excluded acupuncture as an adjuvant to other treatments and other forms of acupuncture were excluded. Seven hundred and nine possibly relevant studies were identified and 10 RCTs were included. The methodological quality of the trials was generally poor. Manual acupuncture was compared to placebo acupuncture in four studies of patients with chronic low back pain, shoulder pain, premenstrual syndrome and allergic rhinitis. Three studies tested AA (two trials) and electroacupuncture (one trial) against no treatment, while three trials compared acupuncture with other active therapeutic controls. The methodological limitations of the included trials make their contribution to the current clinical evidence of acupuncture somewhat limited. The trial for premenstrual syndrome, shoulder pain and chronic low back pain added a limited contribution among those included RCTs. However, well-designed RCTs of acupuncture with a rigorous methodology are in progress or have been completed in Korea and will contribute to establish or contribute to the current progress of research in this field.
Characterization of cp3 reveals a new bri1 allele, bri1-120, and the importance of the LRR domain of BRI1 mediating BR signaling
Yun Shang, Myeong Lee, Jianming Li, Kyoung Nam
BMC Plant Biology , 2011, DOI: 10.1186/1471-2229-11-8
Abstract: Among the mutants showing altered growth patterns compared to wild type, we further characterized cp3, which displayed defective growth and reduced BR sensitivity. We sequenced the genomic DNA spanning BRI1 in the cp3 and found that cp3 has a point mutation in the region encoding the 13th LRR of BRI1, resulting in a change from serine to phenylalanine (S399F). We renamed it bri1-120. We also showed that overexpression of the wild type BRI1 protein rescued the phenotype of bri1-120. Using a GFP-tagged bri1-120 construct, we detected the bri1-120 protein in the plasma membrane, and showed that the phenotypic defects in the rosette leaves of bri1-301, a kinase-inactive weak allele of BRI1, can be restored by the overexpression of the bri1-120 proteins in bri1-301. We also produced bri1-301 mutants that were wild type in appearance by performing a genetic cross between bri1-301 and bri1-120 plants.We identified a new bri1 allele, bri1-120, whose mutation site has not yet been found or characterized. Our results indicated that the extracellular LRR regions before the 70-amino acid island domain of BRI1 are important for the appropriate cellular functioning of BRI1. Also, we confirmed that a successful interallelic complementation occurs between the extracellular domain mutant allele and the cytoplasmic kinase-inactive mutant allele of BRI1 in vivo.Numerous plant developmental processes, such as germination, cell elongation, photomorphogenic responses, and male fertility are regulated by the plant-specific steroidal hormones, brassinosteroids (BR). BR-biosynthetic or BR-perceiving mutants have exhibited defective growth patterns in various tissues that persist throughout their entire life span, indicating the critical role of BR in plant development [1,2]. Although studies researching the BR signaling process began much more recently than any of the other plant hormones, the identification of BRASSINOSTEROID-INSENSITIVE1 (BRI1), a receptor of BR [3], and several other imp
Magnetostrictive Micro Mirrors for an Optical Switch Matrix
Heung-Shik Lee,Chongdu Cho,Myeong-Woo Cho
Sensors , 2007, DOI: 10.3390/s7102174
Abstract: We have developed a wireless-controlled compact optical switch by siliconmicromachining techniques with DC magnetron sputtering. For the optical switchingoperation, micro mirror is designed as cantilever shape size of 5mm×800μm×50μm.TbDyFe film is sputter-deposited on the upper side of the mirror with the condition as: Argas pressure below 1.2×10-9 torr, DC input power of 180W and heating temperature of up to250°C for the wireless control of each component. Mirrors are actuated by externallyapplied magnetic fields for the micro application. Applied beam path can be changedaccording to the direction and the magnitude of applied magnetic field. Reflectivity changes,M-H curves and X-ray diffractions of sputtered mirrors are measured to determine magneto-optical, magneto-elastic properties with variation in sputtered film thickness. The deflectedangle-magnetic field characteristics of the fabricated mirror are measured.
Does moxibustion work? An overview of systematic reviews
Myeong Soo Lee, Jung Won Kang, Edzard Ernst
BMC Research Notes , 2010, DOI: 10.1186/1756-0500-3-284
Abstract: Electronic searches were conducted to locate all SRs of moxibustion for any condition. Data were extracted by two authors according to predefined criteria.Ten SRs met our inclusion criteria, which related to the following conditions: cancer, ulcerative colitis, stroke rehabilitation, constipation, hypertension, pain conditions and breech presentation. Their conclusions were contradictory in several instances. Relatively clear evidence emerged to suggest that moxibustion is effective for breech presentation.Based on evidence from the currently available SRs, the effectiveness of moxibustion has been demonstrated for several conditions; however, due to the poor quality of the primary studies, there remains considerable uncertainty.Moxibustion is an East Asian therapeutic method that uses the heat generated by burning herbal preparations containing Artemisia vulgaris to stimulate acupuncture points [1]. According to the theory of traditional medicine, heat is usually applied to acupuncture points during moxibustion to cure diseases by regulating the function of meridians and visceral organs. A possible explanation for how moxibustion works is that the heat stimulates acupuncture points, which increases qi circulation and relieves qi stagnation, leading to an improved disease state [2].Acupuncture stimulation, which involves thrusting or twisting needles, results in various biochemical reactions that can have effects throughout the body. Unlike acupuncture, moxibustion uses heat stimulation at various temperature levels, ranging from mild skin warming to tissue damage from burning. This heat stimulation can yield inflammatory responses and induce vascular changes [2].Although moxibustion is often used as a symptomatic treatment for a wide range of conditions in clinical practice, e.g., arthritis, gastrointestinal problems, gynaecological complaints and stroke rehabilitation, its clinical effectiveness remains uncertain [3-5], and many experts doubt its biological plausi
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