Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99


Any time

2019 ( 22 )

2018 ( 21 )

2017 ( 19 )

2016 ( 36 )

Custom range...

Search Results: 1 - 10 of 3555 matches for " Mustafa Tekin "
All listed articles are free for downloading (OA Articles)
Page 1 /3555
Display every page Item
Bat ’da Sekülerlik ve Türkiye Müslümanl n n Seküler erimleri (Secularism in the West and Secular Implications of Turkish Islam)
Mustafa Tekin
?nsan & Toplum Dergisi , 2012, DOI: http://dx.doi.org/10.12658/human.society.2.4.m0051
Abstract: This article aims to reveal the secular contents of Muslim practices in Turkey. Secularism is a concept that originated in the west and it has developed a context within its historical process. The relationship between the west and Christianity is important in this process and secularism which has gained a structural qualification in the western world, is a result of this relationship. This article will try to analyze the context of secularism in the western history, and then will discuss the Muslim experiences and its relationship with secularism in Turkey. In this context, we can say that there are some similarities and differences in the meaning of secularism in Turkey and in the West. These differences can be due to the religions, cultures and societies of two societies. It should be noted that the impacts of secularism can be seen in some practices of daily life within the modernization process, which could be traced back to the Tanzimat period in the Ottoman Empire. The article will analyze the impacts of secularism on Muslim practices within the context of language, daily life and religious practices. The mindsets and practices indicate that secularism has had some impacts in Turkey.
The extended uses of Foley catheter in plastic surgery
Simsek Tekin,Keskin Mustafa,Eroglu Lütfi
Indian Journal of Plastic Surgery , 2006,
Further Increase in the Expression of Activation Markers on Monocyte-Derived Dendritic Cells in Coronary Artery Disease Patients with Ectasia Compared to Patients with Coronary Artery Disease Alone
Nesligul Yildirim,Ishak Ozel Tekin,Mehmet Arasli,Mustafa Aydin
Mediators of Inflammation , 2010, DOI: 10.1155/2010/748919
Abstract: Background. Coronary artery ectasia (CAE) is defined as localized or diffuse dilation of the coronary arteries. There are scarce data about the role of dendritic cells in CAE development. In this study we investigated the activation markers on the surface of monocyte-derived dendritic cells (mDCs) in coronary artery disease (CAD) patients with or without CAE. Method. The study consisted of 6 patients who had obstructive CAD with CAE, 6 CAD patients without CAE and 6 subjects with angiographically normal coronary arteries. mDCs were cultivated from peripheral blood monocytes. Surface activation markers were detected by flow cytometry. Results. CAD patients with CAE were detected to have significantly higher mean fluorescence intensities of CD11b, CD11c, CD54 , CD83, CD86 and MHC Class II molecules on mDCs in comparison to CAD patients without CAE and normal controls ( for all). A significant positive correlation was found between the number of vessels with CAE and the levels of CD11c, CD86, and MHC Class II molecules. Conclusion. mDCs display an increased cell surface concentration of activation molecules in CAD patients with CAE compared to patients with CAD alone. DC activation may play an important role for CAE development in patients with CAD. 1. Introduction Coronary artery ectasia (CAE) has been defined as segmental or diffuse luminal dilatation of the coronary arteries in coronary angiography [1]. CAE is a rare finding among coronary artery anomalies and considered to be congenital in 10–20% of the cases while the remaining are acquired in origin [2]. The common coexistence of CAE with coronary artery disease (CAD) suggests that it may be a variant of atherosclerosis [2, 3]. However it is not clear why some patients with obstructive CAD develop CAE whereas most do not. Dendritic cells (DCs) are potent antigen presenting and immune modulating cells with the unique ability to initiate a primary immune response to certain antigens by the activation of T lymphocytes [4, 5]. To acquire the ability to contact and activate T cells, DCs must undergo a maturation process with the upregulation of antigen presenting molecules including MHC class I and class II, adhesion molecules (CD11a, CD11b, CD54, CD50, CD58) and costimulatory molecules (CD40, CD80, CD86) [4–6]. In addition to these relatively well-known cell surface molecules; CD83 which is the hallmark of mature DCs and CD11c expressions were also reported to have functions in the regulation of antigen presentation and enhancement of T cell activation in the recent reports [7, 8]. During the development
Challenges in Whole Exome Sequencing: An Example from Hereditary Deafness
Asli Sirmaci, Yvonne J. K. Edwards, Hatice Akay, Mustafa Tekin
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0032000
Abstract: Whole exome sequencing provides unprecedented opportunities to identify causative DNA variants in rare Mendelian disorders. Finding the responsible mutation via traditional methods in families with hearing loss is difficult due to a high degree of genetic heterogeneity. In this study we combined autozygosity mapping and whole exome sequencing in a family with 3 affected children having nonsyndromic hearing loss born to consanguineous parents. Two novel missense homozygous variants, c.508C>A (p.H170N) in GIPC3 and c.1328C>T (p.T443M) in ZNF57, were identified in the same ~6 Mb autozygous region on chromosome 19 in affected members of the family. Both variants co-segregated with the phenotype and were absent in 335 ethnicity-matched controls. Biallelic GIPC3 mutations have recently been reported to cause autosomal recessive nonsyndromic sensorineural hearing loss. Thus we conclude that the hearing loss in the family described in this report is caused by a novel missense mutation in GIPC3. Identified variant in GIPC3 had a low read depth, which was initially filtered out during the analysis leaving ZNF57 as the only potential causative gene. This study highlights some of the challenges in the analyses of whole exome data in the bid to establish the true causative variant in Mendelian disease.
Co-existence of other copy number variations with 22q11.2 deletion or duplication: a modifier for variable phenotypes of the syndrome?
Deling Li, Mustafa Tekin, Maria Buch, Yao-Shan Fan
Molecular Cytogenetics , 2012, DOI: 10.1186/1755-8166-5-18
Abstract: We observed additional copy number variations (CNVs) in 2 of 15 cases with a 22q11.2 deletion or duplication. Both cases were newborn babies referred for severe congenital heart defects. The first case had a deletion with a size of approximately 1.56 Mb involving multiple genes including STS in the Xp22.31 region along with a 22q11.2 deletion. The second case had a duplication of 605 kb in the 15q13.3 region encompassing CHRNA7 and a deletion of 209 kb involving the RBFOX1 gene in the 16p13.2 region, in addition to 22q11.2 duplication.Our observations have shown that additional CNVs are not rare (2/15, 13%) in patients with a 22q11.2 deletion or duplication. We speculate that these CNVs may contribute to phenotype variations of 22q11.2 microdeletion/duplication syndromes as genomic modifiers.It is well known that the phenotype of patients with 22q11.2 microdeletion or microduplication can be extremely variable from near normal to severe developmental disabilities including congenital heart defects, learning disabilities, and risk of psychological problems such as attention-deficit hyperactivity disorder, autism-spectrum disorders and schizophrenia [1,2]. The mechanisms that lead to extreme phenotype variations in this syndrome remain unknown. Prior to the clinical use of microarray based comparative genomic hybridization (array CGH), vast majority of patients with a 22q11.2 deletion or duplication were diagnosed by FISH [3-5], and therefore genomic changes other than the 22q11.2 region were barely known. Here, we report additional genomic aberrations detected by array CGH in two newborns, one had a deletion and the other had a duplication of the 22q11.2 region.The patient was an infant girl, 15 days of age, born to a 23 year old healthy mother. The baby was delivered at the 38th week of gestation by C-section due to nuchal cord. The baby weighted 2.9 kg, with Apgar scores 8 at 1 min, 9 at 5 min, and 9 at 10 min. Management of the infant at delivery included stimulat
Sport and nationalism interaction: sports’ place and importance creating national identity
Mustafa Ya?ar ?ahin,Fatih Yenel,Tekin ?olako?lu
International Journal of Human Sciences , 2010,
Abstract: The aim of his study, developing nation and national state, legitimation of imperialist policies, developing national independent struggle, searching the interaction of sport and nationalism as a politic and ideologic action effecting in socia-cultural and politic area and also determinig the place and importance of sport. As a result; the role of sport according to nationalism are; developing states, creating national identity and national rivalry, nationalism that needs politics being a factor in sport competations, sports’ effects in creating social classes and national identities by active and aggressive, powerful masculinity myth incarnation, sports’ being an area of creating people as “ us” and also passing beyond the little inner parts and displacing of itself, having success in sport, reinforce patriotism by defining national sport concepts, national awareness of international sport, establishing national consciousness, pride and unity, also thinking sport as an instrument of national unity through the miscellaneous groups.
The frequency of FV G1691A and PT G20210A mutations in an Albanian population
A. Avni Atay,Mustafa Tekin,Klodian Allajalebeu,Yonca E?in
Turkish Journal of Hematology , 2011,
Prevalence of anti-HDV and HDAg in patients with chronic hepatitis B
Mustafa Do?an,Hayati Güne?,Rafet Mete,Tekin Ta?
Dicle Medical Journal , 2013,
Abstract: Objective: In this study, it is aimed to evaluate the correlationof the test results of anti-HDV and HDAg in patientswith chronic HBV infection and to collect data concerningHDV epidemiology.Materials and methods: Anti-HDV and HDAg test resultsand demographic data of the patients with chronic HBVinfection by gastroenterology and infectious diseasesin Agri State Hospital between January 2009-May 2012were analyzed retrospectively. HBsAg and Anti-HBc IgMtests were performed with macroelisa, anti-HDV andHDAg were tested with microelisa.Results: A total of 787 patients constituting 315(40.0%)females and 472(60.0%) males were included in thestudy. All the patients were HBsAg positive and Anti-HBcIgM negative. Of these patients, 55(7.0%) cases wereonly anti-HDV positive; 19(2.4%) were only HDAg positiveand two cases were both anti-HDV and HDAg positive.A total of 76(9.7%) patients had positive findings ofHDV infection. The mean age of HDV-positive patientswas 42.1±15.2 (11-77 years); of these 36(47.4) were femaleand 40(52.6) were male.Conclusion: In patients with chronic viral hepatitis, HDVinfection still remains significant. In our study HDV infectionrate was detected as 9.7%. Although this rate is lowerthan the earlier reports of the same region, it is above thenational average.Key words: HDV, HDAg, delta antigen, anti-HDV, chronic hepatitis B, pain
Wagner classification and culture analysis of diabetic foot infection
Fatma Bozkurt,Recep Tekin,Mustafa Kemal ?elen,Celal Ayaz
Dicle Medical Journal , 2011,
Abstract: The aim of this study was to determine the concordance ratio between microorganisms isolated from deep tissue culture and those from superficial culture in patients with diabetic foot according to Wagner’s wound classification method.Materials and methods: A total of 63 patients with Diabetic foot infection, who were admitted to Dicle University Hospital between October 2006 and November 2007, were included into the study. Wagner’s classification method was used for wound classification. For microbiologic studies superficial and deep tissue specimens were obtained from each patient, and were rapidly sent to laboratory for aerob and anaerob cultures. Microbiologic data were analyzed and interpreted in line with sensitivity and specifity formula.Results: Thirty-eight (60%) of the patients were in Wagner’s classification ≤2, while 25 (40%) patients were Wagner’s classification ≥3. According to our culture results, 66 (69%) Gr (+) and 30 (31%) Gr (-) microorganisms grew in Wagner classification ≤2 patients. While in Wagner classification ≥3; 25 (35%) Gr (+) and 46 (65%) Gr (-) microorganisms grew. Microorganisms grew in 89% of superficial cultures and 64% of the deep tissue cultures in patients with Wagner classification ≤2, while microorganism grew in 64% of Wagner classification ≥3.Conclusion: In ulcers of diabetic food infections, initial treatment should be started according to result of sterile superficial culture, but deep tissue culture should be taken, if unresponsive to initial treatment.
The Relationship of Fuhrman Nuclear Grade, Tumor Stage and Sarcomatoid Differentiation with Survival in Renal Cell Carcinomas
Ebru Ta?tekin,Fulya ?z Puyan,Mustafa Kaplan,Burcu Toku?
Balkan Medical Journal , 2012,
Abstract: Objective: Renal cell carcinoma derived from tubular epithelium is one of the malignant tumors of the kidney. We have investigated the histological features, pathological stage, nuclear grade and sarcomatoid differentiation of these tumors. Material and Methods: Histological slides from seventy-eight nephrectomy specimens diagnosed as renal cell carcinoma between 2000 and 2008 were reevaluated according to the 2004 World Health Organization classification system of kidney tumors. Reclassified cases were collected in five groups and were scored for Fuhrman nuclear grading, stage, sarcomatoid differentiation and survival rate. Results: In our study, cases with high nuclear grade, advanced stage and sarcomatoid differentiation revealed poor survival rates (p<0.05). In conclusion, the correlation between prognostic histopathological parameters and survival rates was consistent with literature findings. Conclusion: Fuhrman nuclear grading, stage and sarcomatoid differentiation are important parameters and are related factors in survival when investigating renal cell carcinomas. Fuhrman nuclear grading must be evaluated correctly and the highest grade should be reported. Although there aren’t enough studies about sarcomatoid differentiation, its presence significantly decreases survival rates. It is very important to state histopathological parameters including sarcomatoid differentiation precisely on the pathology report.
Page 1 /3555
Display every page Item

Copyright © 2008-2017 Open Access Library. All rights reserved.