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Search Results: 1 - 10 of 8433 matches for " Mukunda Fran?ois Lusamaki "
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Effect of TB Therapy on the Health and Nutritional Status of Infants Aged 6 Months to 5 Years Diagnosed with Latent TB  [PDF]
Kasai Emmanuel Tebandite, Kampunzu Véronique Muyobela, Mukunda Franois Lusamaki, Bukaka Gaspard Mande, Gwendiza Jean Mopepe, Sadiki Dady Falay, Likele Bibi Batoko, Oloma Antoine Tshomba, Dauly Nestor Ngbonda, Opara Jean Pierre Alworong’a, Justin Ntokamunda Kadima
Journal of Tuberculosis Research (JTR) , 2018, DOI: 10.4236/jtr.2018.64022
Abstract: Background: Infants with latent tuberculosis are often subject to high morbidity, nutritional deficiency and mortality. Early treatment can prevent the onset of TB by reducing morbidity and improving nutritional status. This paper assessed whether preventive chemotherapy for TB can improve health and nutritional status of infants diagnosed with latent TB in Kisangani City. Method: Children diagnosed TB+ by tuberculin skin test and other clinical examinations were treated with Rifampicin, Isoniazid, Pyrazinamide and Ethambutol. Clinical symptoms and nutritional status were determined before to start treatment and at the 5th month of treatment. Results: Out of 161 infants treated, 73 (45.3%) were <1 year old, 49 (30.4%) were 1 - 2 years old and 39 (24.2%) were 3 - 5 years old. Both boys and girls were almost equally represented (50.3/49.7%). The proportion of infants with fever (T > 37°C) was 62.7% before treatment and 17.4% at the 5th month of treatment; the difference was statistically significant (p < 0.001). Similarly, the proportion of children with weights below the ideal weight adjusted for each age decreased from 21.7% before treatment to 8.1% after treatment. Infants younger than one year were more likely to have fever than older children, while girls were more likely to be malnourished than boys (p < 0.05) before treatment, but the recovery rates were not different. Conclusion: Treatment of infants diagnosed of latent TB prevents TB disease and improves nutritional status, but not in all cases. Control of fever and weight gain can be an indicator of good outcome in poor health care settings.
The Changes in Cameroon’s Public Television in the Advent of Digital Switchover: The Impact of Technological Innovation on Audio-Visual Public Policies  [PDF]
Franois Wakata Bolvine
Advances in Journalism and Communication (AJC) , 2017, DOI: 10.4236/ajc.2017.51001
Abstract: Technological innovation strongly impacts the lives of citizens as a whole and is followed by serious consequences on national public policies and on the sector directly concerned. The dynamics of change in the national audio-visual landscape with the public service television engaged in the digital switch-over process is indeed the core of this study. It reveals how innovation has impelled policy-makers to develop a comprehensive strategy, leading to objectives and decisions to completely reshape the national audio-visual landscape with regard to legal, institutional, infrastructural, economic and cultural aspects; and, specifically, public television in its organization, functioning, mission as well as in its uses.
Media and Justice in Cameroon or the Dynamics of a Dual Interaction  [PDF]
Franois Wakata Bolvine
Advances in Journalism and Communication (AJC) , 2017, DOI: 10.4236/ajc.2017.52006
Abstract: Information on justice in Cameroon examines the balance of power between justice and the media in an environment characterised by an interaction highlighting tension between the objectives of the field of journalism confronted with constrains and the rigours of a judicial environment that preserves its tenets. Referring to the TOURAINE approach which associates the sociology of action with the theory of conflicts, prompts strategies of actors vacillating between conflict and collaboration, in a dynamics with well-defined requirements: if legal matters easily become media events, the contrary, namely the influence of justice by the press is hardly recognised by the judge, confronted with the norms governing his socio-professional group. Influence, if necessary, emerges from two narrow channels: speedy proceedings and exemplary sentence.
When neurological symptoms hides a nephrologic pathology and a cardiac abnormality  [PDF]
Clotilde Muller, Bernadette Faller, Franois Sellal, Franois Chantrel
Open Journal of Internal Medicine (OJIM) , 2011, DOI: 10.4236/ojim.2011.11002
Abstract: We bring report the case of a young woman who presents with neurological symptoms, and to which the practised investigations led to the discovery in chain of unexpected pathologies. These neurological disorders were revealing of the picture associating a nephrotic syndrome and a patent foramen ovale. This foramen was the major route of a rain of emboles ring peripheral favored by the nephrotic syndrome towards the cerebral hemispheres.
Labeled HepasphereTM behavior during venous drainage simulation at 1.5T  [PDF]
Hassan Jassar, Franois Langevin
Journal of Biomedical Science and Engineering (JBiSE) , 2010, DOI: 10.4236/jbise.2010.311142
Abstract: Stability of the magnetic resonance (MR) contrast agent inside vascular occlusion agents is important for their localization with magnetic resonance imaging (MRI). The aim of this paper is to study the behaviour of the superparamagnetic iron oxide (SPIO) within Hepaspheres? microparticles (MP) by MRI when they are submitted to negative pressure induced by venous drainage of a tumor. Therefore, a venous drainage model was established and three parameters were taken into account according to physiologic parameters in tumors: pH, temperature and flow blood rate. Four cycles of pumping were performed with the presence of labeled Hepaspheres? with Endorem®. Several MR images of MP and perfusion liquid were taken before and after pumping. Endorem® release was determined after correction of non-uniformity intensities in MR images. Intensity variation according to spatial position, coil and MR acquisition parameters was studied. Labeled microparticles (LB*MP) appeared as black spots in MRI images whatever duration and pH. Our model demonstrates the stability of the SPIO inside the occlusion agent during time. Moreover, the proposed correction method proves the reduction of the intensity non-uniformity in MRI images.
Architectural Model of a Biological Retina Using Cellular Automata  [PDF]
Franois Devillard, Bernard Heit
Journal of Computer and Communications (JCC) , 2014, DOI: 10.4236/jcc.2014.214008
Abstract: Developments in neurophysiology focusing on foveal vision have characterized more and more precisely the spatiotemporal processing that is well adapted to the regularization of the visual information within the retina. The works described in this article focus on a simplified architectural model based on features and mechanisms of adaptation in the retina. Similarly to the biological retina, which transforms luminance information into a series of encoded representations of image characteristics transmitted to the brain, our structural model allows us to reveal more information in the scene. Our modeling of the different functional pathways permits the mapping of important complementary information types at abstract levels of image analysis, and thereby allows a better exploitation of visual clues. Our model is based on a distributed cellular automata network and simulates the retinal processing of stimuli that are stationary or in motion. Thanks to its capacity for dynamic adaptation, our model can adapt itself to different scenes (e.g., bright and dim, stationary and moving, etc.) and can parallelize those processing steps that can be supported by parallel calculators.
Ethical Decision-Making in Clinical Nutritional Practice  [PDF]
Franois P. R. de Villiers
Food and Nutrition Sciences (FNS) , 2011, DOI: 10.4236/fns.2011.26089
Abstract: Ethics requires a critical evaluation of assumptions and arguments about norms and values; what should be done and what should not. Practitioners should practice ethically, and the professions should be at the forefront of applied ethics. There are four principles, patient autonomy, beneficence, non-maleficence and justice, which are guides to ethical day-to-day practice. Patient autonomy: Autonomy means self-rule by persons of their thoughts and actions. Patient autonomy requires the practitioner to realise that patients have the right to be involved in decision-making on their own behalf. Beneficence refers to the duty of the practitioner to do the best for the patient. The benefits of breast-feeding are many, and the eventual outcome on health enormous. Nevertheless, health-care workers are diffident in promoting breast-feeding, and readily accept excuses for not breast-feeding, contrary to the principle of beneficence. Non-maleficence refers to the duty of the practitioner not to do harm; it requires the practitioner to withhold harmful therapies; Vitamin E, for example, has been proven to be ineffective as an antioxidant in humans, and large doses have been proven to increase mortality. Yet these are the doses available in supermarkets and “Health shops”. Nutritionists should actively advise against harmful “dietary supplementation”. Distributive justice requires every patient to have an equal opportunity to obtain appropriate therapy. There are relatively few nutritionists and dieticians in South Africa, and indeed in the entire African continent, but proportionately even fewer in the areas of greatest need. A case illustrates the application of these ethical principles to show how they can be applied to our daily practice. Using these four principles is a practical approach to solving ethical dilemmas.
Microwave-Assisted Polyesterification Process in Bulk and Aqueous Media  [PDF]
Nassima Mazouzi-Sennour, Franois Henry
International Journal of Organic Chemistry (IJOC) , 2014, DOI: 10.4236/ijoc.2014.41003
Abstract: Microwave irradiation in polymer chemistry is an emerging research field. This type of heating can enhance the rate of reaction and improve the specific characteristics of the formed polymer. In this context, the present paper focuses on selective microwave (MW) heating and its influence on the polyesterification reaction. As a reaction model, the polyesterification of sebacic acid with decanediol, in bulk and in aqueous emulsion is investigated. The reaction was catalyzed by using 4-dodecylbenzenesulfonic acid (DBSA), which plays a catalytic and surfactant role. Both in bulk and in aqueous media, a polyester with higher molecular weight is obtained in MW heating compared to the conventional heating.
Influence of Microwave Irradiation on Hydrolysis Reaction of Sunflower Oil in Aqueous Emulsion  [PDF]
Nassima Mazouzi-Sennour, Franois Henry
International Journal of Organic Chemistry (IJOC) , 2014, DOI: 10.4236/ijoc.2014.41004
Abstract: Microwave irradiation (MW) has been widely applied as heating in chemical processing. It offers a clean, convenient and inexpensive method of heating which often results in higher yields and shorter reaction times. Here, we study the microwave heating influence on the hydrolysis of the triglyceride (sunflower oil) in aqueous emulsion catalyzed by using 4-dodecylbenzenesulfonic acid (DBSA). The progress of the hydrolysis reaction was determined by Fourier Transform Infrared spectroscopy (FTIR). The effects of temperature, reaction time and the catalyst nature and concentration on the hydrolysis reaction were investigated. The hydrolysis was carried out at temperatures ranging between 90°C and 150°C. The polarity of the reaction medium accelerated this reaction.
Regulation of Breast Cancer Progression by Phosphorylation of the Tumor Suppressor Tropomyosin-1 Alpha  [PDF]
Mouna Zerradi, Franois Houle, Jacques Huot
Journal of Cancer Therapy (JCT) , 2015, DOI: 10.4236/jct.2015.69086
Abstract: Background: Tropomyosin 1 alpha chain (Tm1) is an actin-binding protein that regulates the endothelial cell response to oxidative stress following its phosphorylation at Serine 283 (S283). Tm1 is also a major tumor suppressor in breast cancer. In the present study, we investigated the role of phosphorylation of Tm1 in regulating its tumor suppressor properties. Methods: MDA MB231 breast cancer cells stably overexpressing wild type form of Tm1 or Tm1 mutants (S283A and S283E) were generated. Proliferation and cell viability were assayed by means of the enzymatic cleavage of the tetrazolium salt WST-1 to formazan dye by cellular mitochondrial dehydrogenases. Adhesion assays were performed at various periods of time on cells grown on plastic. Cell migration was evaluated by using the wound-healing assay and by measuring transendothelial migration of cancer cells. Malignant transformation in vitro was determined by using the anchorage-independent growth assay on soft agar. Results: We found that cells expressing the phosphomimetic form of Tm1 S283E/Tm1 are characterized by an increased adhesion to the substratum. Moreover, the migration of MDA-MB231/S283E/Tm1 cells in a wound closure assay is reduced compared to parental cells or those expressing the non-phosphorylatable form of Tm1 (S283A). Similarly, the transendothelial migration of MDA-MB231/S283E/Tm1 cells is also reduced as compared to the other cell lines. Moreover, we found that the cells expressing the S283A mutants form more colonies in soft agar that those expressing the S283E mutants. Conclusion: Phosphorylation of Tm1 at Ser283 contributes to its anti-tumor properties, and this effect results mainly from an increase in cell adhesion associated with a decrease in their migratory and invasive potentials.
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