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Search Results: 1 - 10 of 353 matches for " Moulay Abdellah Bahlaoui "
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Physicochemical 2D-Qsar and 3D Molecular Docking Studies on N-Chlorosulfonyl Isocyanate Analogs as Sterol O-Acyl-Transferase-1 “Soat-1” Inhibitors  [PDF]
Khalid El Akri, Rokaya Mouhibi, Mohamed Zahouily, Na?ma Hanafi, Moulay Abdellah Bahlaoui
Open Journal of Medicinal Chemistry (OJMC) , 2013, DOI: 10.4236/ojmc.2013.34013
Abstract: A series of N-carbonyl-functionalized ureas, carbamates and thiocarbamates derivatives (or N-Chloro sulfonyl isocyanate
“N-CSI”) were involved in linear and nonlinear physicochemical quantitative structure-activity relationship
“QSAR” analysis to find out the structural keys to control the inhibition against Sterol O-Acyl-Transferase-1 “SOAT-1”.
The results indicate the important effects of geometrical and chemical descriptors on the inhibitory activity of SOAT-1.
The molecules were also screened for three-dimensional molecular docking on the crystal structure of ACAT-1 (1WL5
for ACAT-1, PDB). A comparison between 2D-QSAR and 3D molecular docking studies shows that the latter confirm
the first results and represent a good prediction of the chemical and physical nature of interactions between our drug
molecules and enzyme SOAT-1.
Advanced Low Energy Adaptive Clustering Hierarchy
Ezzati Abdellah,,Said Benalla,,Abderrahim BENI HSSANE,Moulay Lahcen HASNAOUI
International Journal on Computer Science and Engineering , 2010,
Abstract: The use of Wireless Sensor Networks (WSNs) is anticipated to bring enormous changes in data gathering, processing and dissemination for different environments and applications. However, a WSN is a power constrained system, since nodes run on limited power batteries which shorten its lifespan. Prolonging the network lifetime depends on efficient management of sensing node energy resource. Hierarchicalrouting protocols are best known in regard to energy efficiency. By using a clustering technique hierarchical routing protocols greatly minimize energy consumed in collecting and disseminating data. Low Energy Adaptive Clustering Hierarchy (LEACH) is one of the undamental protocols in this class. In this paper we propose Advanced LEACH (A-LEACH), a heterogeneous-energy protocol to decrease probability of failure nodes and to prolong the time interval before the death of the first node (we refer to as stability period) and increasing the lifetime in heterogeneous WSNs, which is crucial for many applications.
Improved and Balanced LEACH for heterogeneous wireless sensor networks
BEN ALLA Said,EZZATI abdellah,,Abderrahim BENI HSSANE,,Moulay Lahcen
International Journal on Computer Science and Engineering , 2010,
Abstract: While wireless sensor networks (WSN) is a power constrained system, since nodes run on limited power batteries which shorten its lifespan. Prolonging the network lifetime depends on efficient management of sensing node energy resource. Energy consumption is therefore one of the most crucial design issues in WSN. Hierarchical routing protocols are best known in regard to energy efficiency. By using a clustering technique hierarchical routing protocols greatly minimize energy consumed in collecting and disseminating data. In this paper we propose Improved and Balanced LEACH (IB-LEACH), a heterogeneous-energy protocol propose a new method to decrease probability of failure nodes and to prolong the time interval before the death of the first node (we refer to as stability period) and increasing the lifetime in heterogeneous WSNs, which is crucial for many applications. We study the impact of heterogeneity of nodes, in terms of their energy, in wireless sensor networks that are hierarchically clustered. In these networks some high-energy nodes called NCG nodes (Normal node/Cluster Head/ Gateway) become “cluster heads” to aggregate the data of their cluster members and transmit it to the chosen “Gateways” that requires the minimum communication energy to reduce the energy consumption of cluster head and decrease probability of failure nodes. The simulation results demonstrated that new protocol is more energy efficient and is more effective in prolonging the network life time and a stability period compared to LEACH and SEP.
Performance of Distributed System
Abdellah Ezzati,Abderrahim Beni hssane,Moulay Lahcen Hasnaoui
International Journal of Computer Science Issues , 2011,
Abstract: Many distributed systems are still too large to be handled. Thus, it's important to find techniques that can be used to extend the size of the systems that can be verified and analyzed. In this paper, we study the qualitative and quantitative performance of the distributed systems that can be interacting with each other by using Temporized Stochastic Petri Net (TSPN). We consider then the composition asynchronous operation for deducing properties of a global distributed system from the properties of its components. Introduction of a structured interface net allows us to preserve properties of components in the global system.
Experimental Design-Based Response Surface Methodology Optimization for Synthesis of β-Mercapto Carbonyl Derivatives as Antimycobacterial Drugs Catalyzed by Calcium Pyrophosphate
Younes Abrouki,Abdelkader Anouzla,Hayat Loukili,Jamal Bennazha,Rabiaa Lotfi,Ahmed Rayadh,My Abdellah Bahlaoui,Sa?d Sebti,Driss Zakarya,Mohamed Zahouily
International Journal of Medicinal Chemistry , 2014, DOI: 10.1155/2014/586437
Abstract: A simple protocol for the efficient preparation of β-mercapto carbonyl derivatives as antimycobacterial drugs has been achieved via Thia-Michael reaction between chalcones derivatives and thiols in the presence of calcium pyrophosphate as a heterogeneous catalyst under mild reaction conditions. The central composite design was used to design an experimental program to provide data to model the effects of various factors on reaction yield . The variables chosen were catalyst weight , reaction time , and solvent volume . The mathematical relationship of reaction yield on the three significant independent variables can be approximated by a nonlinear polynomial model. Predicted values were found to be in good agreement with experimental values. The optimum reaction conditions for reaction model (chalcone and thiophenol) obtained by response surface were applied to other substrates. This procedure provides several advantages such as high yield, clean product formation, and short reaction time. 1. Introduction Tuberculosis is the second most common cause of death from infectious disease. Roughly one-third of the world’s population has been infected with Mycobacterium tuberculosis, and new infections occur at a rate of one per second. In 2007 there were an estimated 13.7 million chronic active cases, and in 2010 there were 8.8 million new cases and 1.45 million deaths. 0.35 million of these deaths occur in those coinfected with HIV [1]. The needs of newly developed antimycobacterial drugs are required for the control of tuberculosis in the present time. In the discovery of new antimycobacterial drugs, the emergence of multidrug-resistant and extensively drug-resistant strains of Mycobacterium has encouraged the researchers to intensify the efforts to discover novel drugs [2]. Recently, the Czech authors showed that the 1,3-diphenyl-3-arylsulfenylpropan-1-one derivatives presented an antimycobacterial activity [3]. Thia-Michael reaction is a convenient route for synthesis of these β-mercapto carbonyl derivatives [4]. Traditionally, this reaction is catalyzed by strong bases [5] such as alkali metal alkoxides, hydroxides, and amines. However the use of either strongly acidic or basic conditions frequently leads to the formation of undesirable side products owing to competing reactions, such as polymerization, self-condensation, and rearrangements. The development of solid basic catalysts which could replace the liquid bases currently used in industrial processes is a major field of today’s catalysis research [6]. In this paper we report a mild and convenient
Nordic Container Port Sustainability Performance—A Conceptual Intelligent Framework  [PDF]
Moulay Hicham Hakam
Journal of Service Science and Management (JSSM) , 2015, DOI: 10.4236/jssm.2015.81002
Abstract: There is a lack of both integrative frameworks for container ports and dedicated ones to the Nordic region as observed in the literature. The purpose of this paper is to fill that gap by proposing a conceptual intelligent sustainability performance management framework for Nordic container ports. First a description of such framework is given where the application of artificial intelligence is vital. Then, scanning the literature for performance measurement, features of ports in the Nordic region and port sustainability is undertaken. A dedicated list of key performance indicators is suggested. Finally, a prototype based on hypothetical data is developed for demonstration purposes.
Optimization Method to Determine Gross Alpha-Beta in Water Samples Using Liquid Scintillation Counter  [PDF]
Waleed M. Abdellah
Journal of Water Resource and Protection (JWARP) , 2013, DOI: 10.4236/jwarp.2013.59092
Abstract:

Liquid scintillation counting (LSC) is an adequate nuclear technique to determine radioactivity levels, as verified by this study for the determination of the gross alpha and beta activities of aqueous samples because of its simplicity and low associated cost comparison with other techniques. This paper discusses a new approach to the monitoring of gross alpha and gross beta activities in water. The method consists of using pulse decay discrimination (PDD) liquid scintillation counting LSC of 2 ml of the sample after conditioning with 12 ml of AB-Ultima Gold LSC cocktail, and PDD 139 condition. Different factors that affected on the counting efficiency were studied such as quench reaction, volume of sample, and type of vial. The gross alpha and gross beta particle activity measurement using 40K and 243Am with different activities concentration for efficiency determination. The calculated detection limits were 0.07 Bq/l and 0.12 Bq/l for gross alpha and gross beta respectively for 500 min measurements of samples produced by concentration of one liter of water.

Jahn–Teller Effect, Crystal Structure and High Temperature Raman Spectroscopy Studies of Ba2-xSrxCuWO6 (0 ≤ x≤ 2) Double Perovskite Oxide.  [PDF]
Amine Ezzahi, Abdellah Elmchaouri
Advances in Materials Physics and Chemistry (AMPC) , 2014, DOI: 10.4236/ampc.2014.44009
Abstract:

The following article has been retracted due to the investigation of complaints received against it. The Editorial Board found that there are conflicts of interests among the authors. The scientific community takes a very strong view on this matter, and the Advances in Materials Physics and Chemistry treats all unethical behaviors seriously. This paper published in Vol. 4 No. 4 61-74, 2014 has been removed from this site.

Title: JahnTeller Effect, Crystal Structure and High Temperature Raman Spectroscopy Studies of Ba2-xSrxCuWO6 (0 x 2) Double Perovskite Oxide.

Authors: Amine Ezzahi, Abdellah Elmchaouri


Estimation of Soil Erosion Risk Using the Universal Soil Loss Equation (USLE) and Geo-Information Technology in Oued El Makhazine Watershed, Morocco  [PDF]
Asma Belasri, Abdellah Lakhouili
Journal of Geographic Information System (JGIS) , 2016, DOI: 10.4236/jgis.2016.81010
Abstract: Soil erosion by water is one of the major threats to soils in the north of Morocco; soil erosion not only decreases agricultural productivity, but also reduces the water availability. In the current study, Oued El Makhazine watershed is selected to estimate annual soil loss using the Universal Soil Loss Equation (USLE), remote sensing (RS) and geographic information system (GIS). GIS data layers including, rainfall erosivity (R), soil erodibility (K), slope length and steepness (LS), cover management (C) and conservation practice (P) factors are computed to determine their effects on average annual soil loss in the area. The resultant map of annual soil erosion shows a maximum soil loss of 735 t·h-1·y-1, about 65.25% (1575 km2), of the watershed ranges between 0 and 95 t·h-1·y-1. Higher soil losses are observed at higher LS factor area. The spatial erosion maps generate with USLE method, remote sensing and GIS can serve as effective inputs in deriving strategies for land planning and management in the environmentally sensitive mountainous areas.
Determination of Radium-226 in Rock Samples by Liquid Scintillation Counter  [PDF]
W. M. Abdellah
Open Journal of Applied Sciences (OJAppS) , 2019, DOI: 10.4236/ojapps.2019.94023
Abstract: The present work examines the validity of using barium as a carrier for radium-226 determination and optimizes the amount added during the radiochemical separation from rock samples. The activity concentration of Ra-226 is determined in rock samples by liquid scintillation spectrometer via its short-lived daughters after the radiochemical separation. The activity of Ra-226 was calculated based on the counts measured in a window set for Po-214 peak. The activity measured by Liquid Scintillation Counter, LSC using Pulse Shape Analysis, PSA. Ba-133 was used for chemical yield. The applied method was tested using a Certified Reference Material, CRM ore number-Dl-1a which shows a good agreement with the certified values. The applied method for measuring Ra-226 has been adapted to be used in rocks such as monazite. The average activity for Ra-226 in rock samples collected from the commercial grade Egyptian monazite was 13.85 ± 2.05 Bq/g with a detection limit 9.58 mBq/g. The optimum conditions have been established during the present work such as precision, cost and time preparation which makes the method useful for radio chemists and the decision makers.
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