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Search Results: 1 - 10 of 254 matches for " Mouhamed Cherif Dial "
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Renal Disease among HIV Positive Patients in Senegal  [PDF]
Khodia Fall, Mouhamadou Moustapha Cissé, Ahmed Tall Lemrabott, Maria Faye, Mouhamed Cherif Dial, Atoumane Faye, Seynabou Fall, Moustapha Faye, Alex Keita, Mansour Mbengue, Seynabou Diagne, Niakhaleen Keita, Bacary Ba, Abdou Niang, Boucar Diouf, El Hadji Fary Ka
Open Journal of Nephrology (OJNeph) , 2017, DOI: 10.4236/ojneph.2017.74012
Abstract: Introduction: Renal disease (RD) in human immunodeficiency virus (HIV) infection is a decisive turning point in the development and prognosis of this disease. In Africa, the prevalence varies between 2.5% and 48.6%. In Senegal, little data are available in the literature. The objective of our study was to describe the epidemiological, clinical, paraclinical, therapeutic and progressional aspects in patients living with HIV (PLWHIV). Patients and methods: This was a retrospective, descriptive and analytical study carried out over a 10-year period in the Department of Internal Medicine and Nephrology at the Aristide Le Dantec Hospital in Dakar, Senegal. We included all 15-year old and above PLHIV with available CD4 count and viral load. Results: Out of 248 PLHIV, 32 had kidney disease (KD), which means a hospital prevalence of 12.9%. The mean age was 51.22 ± 10 years (extremes of 36 and 77 years) with a sex ratio (male/female) of 1.28. Renal signs were dominated by glomerular nephropathy syndrome. It was present at 80%. Tubulo-interstitial nephropathy syndrome and chronic uremic syndrome accounted for 6.25% and 3.1% of cases, respectively. Renal function Impairment was present in 21 patients with 18 cases of acute kidney injury (85.7%) and 3 cases of chronic renal failure (14.3%), including 2 in stage 5 of chronic kidney disease. Renal biopsy (RB) was indicated and performed in 20 (62.5%) patients with glomerular signs in 12 patients (60%). Glomerular lesions were dominated by focal and segmental glomerulosclerosis (FSGS) in 6 cases, membraneous nephropathy (MN) in 4 cases and minimal change disease (MCD) in 2 cases. Tubulo-interstitial and vascular lesions were present in 45% and 12.5% of cases, respectively. In highly active antiretroviral therapy (HAART), 12 (37.5%) patients had total remission, 9 (28.12%) had partial remission. One (3.12%) death from severe metabolic acidosis on chronic renal failure was deplored. Conclusion: This study illustrates the high prevalence of RD in PLHIV in our exercise context.
Coronary Angioplasty in a Low Income Sub-Saharan Country: Situational Analysis  [PDF]
Mouhamed Cherif Mboup, Djibril Marie Ba, Modou Jobe, Massamba Thiam, Khadidiatou Dia, Pape Diadie Fall
World Journal of Cardiovascular Diseases (WJCD) , 2018, DOI: 10.4236/wjcd.2018.812053
Abstract: Introduction: Coronary angioplasty is not widely conducted in sub-Saharan Africa in general and Senegal in particular. The objective of this work was to describe the indications, techniques, results and difficulties of coronary angioplasty in Senegal. Patients and Methods: We prospectively included all patients who underwent coronary angioplasty between July 2012 and November 2014. We evaluated the clinical characteristics, techniques used, and the peri-procedural complications. Results: 110 coronary angioplasties were performed at the cardiac catheterisation unit of the Clinique du Golf in Dakar. The average age of patients was 60.41 ± 10.93 years. A male predominance was noted with a sex ratio of 6.3. Hypertension was found in 57% of patients. The principal indications for coronary angioplasty were for the management of acute coronary syndromes with or without ST elevation, in 29 and 39 patients respectively. The femoral artery was the puncture site in 104 patients. The lesions treated were type A/B1 or B2/C in 53 and 57 cases respectively. The success rates of coronary angioplasties and 30-day mortality were 91% and 0.9% respectively. Conclusion: In sub-Saharan Africa, Senegal in particular, the practice of coronary angioplasty is low. Indeed, many factors linked to socioeconomic status limit the development of coronary angioplasty in Senegal.
Renal Cortical Necrosis: An Unusual Complication of Plasmodium malariae Malaria  [PDF]
Ahmed Tall Lemrabott, Mouhamadou Moustapha Cissé, Sidy Mohamed Seck, Elhadji Fary Ka, Maria Faye, Aliou Ndongo, Cherif Dial, Younoussa Keita, Khodia Fall, Abdou Niang, Boucar Diouf
Open Journal of Nephrology (OJNeph) , 2015, DOI: 10.4236/ojneph.2015.54015
Abstract: Renal cortical necrosis (RCN) is anecdotal in malaria. To our knowledge, RCN secondary to Plasmodium malariae has not yet been published. We report a case of severe malaria complicated by RCN. A 29 year old Senegalese patient was transferred to our department for anuria in a context of severe malaria. The diagnosis was RCN secondary to a severe Plasmodium malariae malaria. Physical examination showed anuria, anaemic syndrome, haemorrhagic syndrome and a generally impaired condition. There was a normocytic normochromic anaemia aplastic, thrombocytopenia leukocytosis of 11.580/mm3, serum creatinine of 12.45 mg/dl and blood urea of 252 mg/dl. The Plasmodium malariae had been shown to thick blood film with high parasite density. The molecular study was able to confirm the infestation of this parasite. Treatment consisted of four haemodialysis sessions and antimalarial molecules. Initial evolution was favourable with a recovery through diuresis and a partial improvement in renal function. Given the persistence of impaired renal function, a renal biopsy was performed. This confirmed the RCN. At last consultation, he had no symptoms and his last glomerular filtration rate (GFR) was 30 mL/min/1.73 m2.
Double Compression of Left Atrium and Pulmonary Artery by a Huge Descending Aortic Aneurysm with Intramural Hematoma Mimicking Pulmonary Embolism: A Case Report  [PDF]
Djibril Marie BA, Aminata Diack, Alain Affangla, Khadidiatou Dia, Mouhamed Cherif Mboup, Mouhamed Leye, Abdoul Kane
World Journal of Cardiovascular Diseases (WJCD) , 2019, DOI: 10.4236/wjcd.2019.96037
Abstract: Hemodynamic instability secondary to left atrial (LA) compression by an aortic aneurysm is a rare entity. We reportthe case of a 43-year old woman with no previous diagnosis of congestive heart failure who was admitted for an initial diagnosis of pulmonary embolism (PE) based on shortness of breath, hypotension and D-Dimers?elevation. The electrocardiogram and blood counts were within normal limits. The chest X-ray revealed widening of the mediastinum. Transthoracic echocardiography demonstrated LA compression by a large descending thoracic aortic aneurysm. Left and right ventricle systolic functions were preserved. Chest angiography showed LA and left pulmonary artery (LPA) compression by a descending aortic aneurysm and an intramural hematoma with no evidence of PE evidence. Emergency surgery could not be done because of her financial status. She was treated medically and was discharged 1week later with significant improvement. However she remained hypotensive.
Management of Pheochromocytoma in Dakar: Diagnostic and Therapeutic Advances throughout 16 Cases  [PDF]
Abdoulaye Leye, Nafy Ndiaye, Yakham Mohamed Leye, Amadou Fall Cisse, Ngoné Diaba Diack, Michel Assane Ndour, Ameth Dieng, Daouda Thioub, Baidy Sy Kane, Alex Bahati, Alpha Omar Touré, Cherif Mohamed Dial, Pape Saloum Diop
Open Journal of Endocrine and Metabolic Diseases (OJEMD) , 2018, DOI: 10.4236/ojemd.2018.81003
Abstract: Introduction: Management of pheochromocytoma faces different challenges leading to misdiagnosis and therapeutic delay in developing countries. The aim of our study was to evaluate the diagnostic and therapeutic features as well as the evolution of our management strategies in hospital setting in recent years in Dakar. Patients and Method: We carried out a retrospective study over 12 years (January 2005 to June 2017), in 4 hospitals in Dakar. We only included patients with established diagnosis of pheochromocytoma upon clinical, biological, radiological and histological arguments. Results: During this period, 16 observations have been collected and were all about female patients. The mean age at the time of diagnosis was 36.81 years. The clinical signs were dominated by hypertension found for 14 patients. At biological examination, hypersecretion catecholamine was found in 13 patients, high urinary metanephrines in 7 patients, high plasmatic metanephrines in 2 patients and raised urinary Vanyl Mandelic Acid (VMA) in 4 patients. Dosage of chromogranin A showed high level for one patient. Abdominal CT scan allowed making the adrenal origin of tumors precise. One patient presented bilateral pheochromocytoma. Before being treated surgically, all patients had had medical preparation. The surgical treatment by median laparotomy consisted of an enucleation of the tumor in 2 patients, and adrenal resection in 11patients.The evolution after surgery was favorable in 12 patients out of 13. One patient died 2 days after surgery by hemodynamic instability. In 2 patients who presented metastases, multidrug therapy with cyclophosphamide, vincristine and dacarbazine was decided after a multidisciplinary meeting, but they died before treatment. Conclusion: Management of pheochromocytomas in developing countries is obviously improving, but the mortality rate remains high. Early diagnosis and perioperative care are to be targeted for better outcome and prognosis of this rare tumor in our areas.
Idiopathic Adult Nephrotic Syndrome: A Clinicopathological Study and Response to Steroid in a Sub-Saharan African Country  [PDF]
Maria Faye, Ahmed Tall Lemrabott, Mouhamadou Moustapha Cisse, Jean De Dieu Nzambaza, Cherif Mouhamed Dia, Sidy Mohamed Seck, Khodia Fall, Moustapha Faye, Elhadji Fary Ka, Abdou Niang, Boucar Diouf
Open Journal of Nephrology (OJNeph) , 2016, DOI: 10.4236/ojneph.2016.62008
Abstract: Introduction: Idiopathic nephrotic syndrome represents 25% to 30% of glomerulonephritis in adults. These glomerulonephritides are responsible of about the half of chronic kidney failure examined as well in United States as in Europe or Africa. The aim of this study was to determine the anatomoclinic, therapeutic and progression patterns of idiopathic nephritic syndrome in Dakar. Patients and Methods: It is a retrospective ten-year study in the nephrology department of Aristide Le Dantec Hospital. Patients with idiopathic nephrotic syndrome were included. We analyzed anatomoclinic, therapeutic and progression data of idiopathic nephrotic syndrome. Results: On 202 patients with nephrotic syndrome, 156 (77%) were primitive. The mean age was 29.7 ± 12 years with a sex ratio of 2.4. Edema was found in 98 patients (62.8%) and hypertension in 63 patients (40%). The mean proteinuria was 6.8 ± 4.8 g/24h. Histologic lesions found at renal biopsy were focal segmental glomerulosclerosis in 71 patients (45.5%), minimal change disease in 68 patients (43.5%) and membranous nephropathy in 8 patients (5%). 134 patients (85.8%) received steroids alone, 12 patients (7.6%) received cyclophosphamide and 4 patients (2.5%) azathioprine in association with steroids. 44 patients (28.2%) reached remission. The factors of poor prognosis were: age, above 40 years, proteinuria above 10 g/24h, existence of renal failure at admission, absence of use of steroids therapy. Conclusion: This study shows that idiopathic nephrotic syndrome is frequent in our country with a prevalence of 77%. The most common lesion found at the renal biopsy is the focal segmental glomerulosclerosis. Remission is found only in 28% which is very low. 33% of patients progress towards chronic kidney disease due to the lack of early diagnosis and the use of traditional medicine.
Corrosion effect on the flexural strength & micro-hardness of ips e-max ceramics  [PDF]
Cherif Mohsen
Open Journal of Stomatology (OJST) , 2011, DOI: 10.4236/ojst.2011.12006
Abstract: Objectives: The effect of ceramics construction (press- able, machinable) and corrosion on flexural strength and micro-hardness was studied. Materials & Methods: Two types of ceramics were tested: IPS e-max Press and IPS e-max CAD. Forty samples were constructed and divided into 2 groups according to the type of ceramics. Each group was then subdivided into 2 subgroups. Subgroups 1 were not subjected to corrosion while subgroups 2 were subjected to corro-sion test. Finally each subgroup was divided into 2 classes according to the type of test: biaxial flexural strength, micro-hardness. Results: There was a sig-nificant difference between the two tested ceramics as regard weight loss as IPS e-max CAD recorded less weight loss than IPS e-max Press. As regard the flex-ural strength, IPS e-max CAD recorded significant higher strength than IPS e-max Press. Corroded sam- ples recorded significant lower flexural strength than non-corroded samples for the two tested ceramics. As regard the Vickers micro-hardness test, the results showed significant difference between the two tested ceramics. IPS e-max CAD recorded higher mi-cro-hardness values than IPS e-max Press. The results also showed that the corroded samples recorded no significant micro-hardness values than non- corroded samples for the two tested ceramics. Conclusions: IPS e-max CAD recorded less weight loss weight loss after being subjected to corrosion test than IPS e-max Press. The method of fabrication affected the flexural strength µ-hardness of ceramic as machinable ceramic (e-max CAD) recorded significant higher data than pressable ceramic (e-mas Press). Corrosion decreased the flexural strength of both tested ceramics but had no effect on micro- hardness.
Vertical marginal gap & retention of ceramic full coverage & inlay retained ceramic fixed partial dentures  [PDF]
Cherif Mohsen
Open Journal of Stomatology (OJST) , 2011, DOI: 10.4236/ojst.2011.14021
Abstract: Objectives: A comparison study between ceramic full coverage FPDs & 3 designs of ceramic inlay retained FPDs regarding vertical marginal gap & retention. Materials & Methods: Twenty samples were construc- ted and divided into 4 groups according to the type of restorations: full coverage, inlay-shaped (occluso-pro- ximal inlay + proximal box), tub-shaped (occluso-pro- ximal inlay), and proximal box-shaped FPDs. All samples were subjected to a vertical marginal gap measurements followed by a retention test. Results: The vertical marginal gap data showed no significant difference between full coverage FPDs, the tub-shap- ed inlay retained FPDs and the proximal box-shaped inlay retained FPDs. While there was a difference between these three designs and the inlay retained FPDs. Regarding retention, the full coverage FPDs recorded higher retentive strengths and was signifi-cant difference than all inlay retained FPDs designs tested. The inlay-shaped design was significant dif-ference than the other two inlay retained FPDs de-signs. Conclusions: There was no significant differ- ence between full coverage FPDs, tub-shaped & pro- ximal box shaped inlay retained FPDs as regard ver- tical marginal discrepancies. While, the inlay-haped design showed the highest vertical marginal discrep- ancies. The premolar & molar retainers for the same type of restorations showed no difference in vertical marginal discrepancies. All measured vertical mar- ginal discrepancies were in the range of clinical ac- ceptance. The full coverage FPDs recorded higher retentive strengths than all inlay retained FPDs de- signs tested. The inlay-shaped design recorded the highest retentive strengths among the three inlay re- tained FPDs designs. There was no difference as re- gard retentive strengths between tub-shaped & pro- ximal box shaped inlay retained FPDs.
Pulmonary Embolism in Young Patients: About 24 Cases at the Cardiology Department of Dakar Principal Hospital in Senegal  [PDF]
Joseph Salvador Mingou, Amadou Tidjani Saadou, Madjiguene Ka, Zoumana Sangaré, Serigne Cheikh Tidiane Ndao, Khadidiatou Dia, Mouhamed Cherif Mboup, Pape Diadié Fall
World Journal of Cardiovascular Diseases (WJCD) , 2019, DOI: 10.4236/wjcd.2019.99056
Abstract: Introduction: Pulmonary embolism is a relatively common life-threatening cardiovascular emergency. It remains a diagnostic problem because of its nonspecific clinical signs. Objective: The general objective was to study pulmonary embolism in young patients admitted to the cardiology department of Dakar Principal Hospital in Senegal. Methodology: This was a retrospective, descriptive and analytical study in the cardiology department of the Dakar Principal Hospital over a period of two (02) years from January 1, 2015 to December 31, 2016 in young patients admitted for pulmonary embolism. Results: We collected 24 patients with a hospital prevalence of 2.18%. The average age was 42.29 years ± 8.41 years with a male predominance (sex ratio of 1.6). The Wells probability score was low in 54.16% of patients and medium in 45.83%. Functional signs were dominated by chest pain (83.33% of cases) followed by dyspnea (79.16% of cases). The thromboembolic risk factors found were gynecological-obstetrical in 16.6% of cases followed by prolonged bed rest. One case of thrombophilia was present with a deficiency of protein C and antithrombin III. The electrocardiogram recorded sinus tachycardia in 29.16% of patients; the Mac Ginn White sign (S1Q3T3) was found in 25% of cases. Echocardiography showed pulmonary arterial hypertension in 12.48% of cases, dilation of the right ventricle and a paradoxical septal motion in 14.28% of cases. CT pulmonary angiography showed 63.63% of cases with bilateral pulmonary embolism; it was unilateral in 22.72% of cases. Long-term anticoagulation was
Simple Subroutine for Inhomogeneous Deployment
Mouhamed Abdulla
Computer Science , 2014, DOI: 10.1109/GIIS.2014.6934284
Abstract: Spatial modeling of wireless networks via analytical means has been considered as a widely practiced mechanism for inference. As a result, some geometrical deployment models have been proposed in literature. Although practical in certain simulation instances, these models do not always produce inhomogeneous nodal geometries in an effective and simple manner for practical deployment situations. Therefore, we conceptualized a flexible approach for realizing random inhomogeneity by proposing the area-specific deployment (ASD) algorithm, which takes into account the clustering tendency of users. Overall, the developed spatial-level network tool has the distinct advantage of automatically producing infinitely many random realizations of users' geometry by simply entering three parameters to the simulator: the size of the cellular network, the number of deployment layers, and the overall quantity of nodes.
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