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Search Results: 1 - 10 of 177 matches for " Montasir Junaid "
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Spindle Cell Carcinoma of the Maxilla: A Case Report of Rare Entity  [PDF]
Montasir Junaid, Maliha Kazi, Sadaf Qadeer
Surgical Science (SS) , 2017, DOI: 10.4236/ss.2017.85025
Abstract: Spindle cell carcinoma also known as sarcomatoid carcinoma is a rare highly aggressive tumor which is histologically different from squamous cell ca and mesenchymal cancers. Only hands full of cases have been reported in literature since 1957 and hence no proper treatment protocol has been devised yet. We present such a case of thirty-four-year-old female who presented with spindle cell carcinoma of the maxilla at our department and was treated with extensive surgery followed by chemotherapy and radiation therapy. Spindle cell carcinoma is generally associated with poor prognosis and hence literature supports use of post operative Chemo and Radiotherapy for better result and decrease chance of local recurrence.
Quality of Life after Functional Endoscopic Sinus Surgery in Patients with Chronic Rhinosinusitis  [PDF]
Sadaf Qadeer, Shabbir Akhtar, Montasir Junaid, Muhammad Sohail Halim
International Journal of Otolaryngology and Head & Neck Surgery (IJOHNS) , 2018, DOI: 10.4236/ijohns.2018.74020
Abstract: Chronic Rhinosinusitis (CRS) is a group of disorders characterized by the inflammation of mucosa of the nasal passages and paranasal sinuses. It includes chronic rhinosinusitis with polyps, CRS without polyps and Allergic Fungal Sinusitis (AFS). This debilitating disease causes negative impact on quality of life (QOL) of patients. Functional endoscopic sinus surgery (FESS) is the mainstay of surgical treatment for patients and improves QOL of patients. This subjective assessment of QOL can be measured by disease specific questionnaires. SNOT-22 questionnaire is widely used and validated questionnaire for this purpose. Prospective study was done on 54 patients. Data were collected using SNOT-22 questionnaire and filled in pre-operative period then in post-operative follow-up visits on 1st, 3rd, 6th and 12th months. Paired sample t-test was used to compare pre-operative and post-operative SNOT scores and multivariate generalized linear model was used to estimate regression parameters for SNOT scores in CRS with polyp and AFS in comparison of CRS without polyps. Out of 54 patients, 59.3% were males, mean age was 35.98, 29.6% were in CRS without polyp group, 44.4% and 25.9% were in CRS with polyps and AFS group. Recurrence occurred in 7.4%, revision surgery required in 3.7% while 22.2% had history of asthma. Paired sample t-test showed statistical significant reduction in post-operative SNOT scores. Linear model results showed SNOT scores in CRS with polyp group was significantly reduced. Thus FESS provides significant improvement in QOL of patients in chronic rhinosinusitis.
Successful management of aggressive fibromatosis of the neck using wide surgical excision: a case report
Zain A Sobani, Montasir Junaid, Mumtaz J Khan
Journal of Medical Case Reports , 2011, DOI: 10.1186/1752-1947-5-244
Abstract: We report the case of a 39-year-old Pakistani man who presented with a two-month history of a lump on the right side of his neck. The mass was excised and histopathological analysis revealed a case of aggressive fibromatosis.Due to the rarity of the condition no guidelines are available on the indications and extent of each modality. Due to its aggressive behavior and tendency to invade local structures and recur, a multi-modality management strategy is usually employed. On the basis of this case, we suggest that aggressive surgery is a viable management option and may be successfully used as a single modality treatment.Aggressive fibromatosis (AF) is a benign tumor, thought to arise from deep musculoaponeurotic structures [1], characterized by local invasion and recurrence that can occur anywhere in the body. It has rarely been reported in the head and neck region, with 179 cases documented between 1968 and 2008.Due to the tendency of AF to invade local structures and recur, a multi-modality management strategy is usually employed. However due to its rarity in the head and neck, no guidelines are available on the indications and extent of each modality. Here we report a case of AF of the neck successfully managed by wide surgical excision; with no signs of recurrence 22 months after surgery.A 39-year-old Pakistani man had presented to our General Surgery clinic with a two-month history of a lump on the right side of his neck. There were no associated symptoms. There was no history of tobacco or irritant use. On physical examination a fixed mass, 4 cm in size, was palpated in right level III. It was not associated with any changes in the overlying skin. An examination of his upper aerodigestive tract was unremarkable. The mass was excised by a general surgeon. Histopathological analysis demonstrated spindle-shaped cells with no identifiable nuclear pleomorphism or mitotic activity. The cells stained positive for anti-smooth muscle actin (ASMA), favoring a smooth mus
Diagnostic Accuracy of Fine Needle Aspiration Cytology in Parotid Lesions
Naeem Sultan Ali,Shabbir Akhtar,Montasir Junaid,Sohail Awan,Kanwal Aftab
ISRN Surgery , 2011, DOI: 10.5402/2011/721525
Abstract: Objective. Histopathology of parotid gland tumors is extremely varied and complex due to heterogeneous cellular composition. Preoperative diagnostic tools include fine needle aspiration cytology, the role of which remains controversial. The aim of this paper is to evaluate the usefulness and accuracy of fine needle aspiration cytology (FNAC) in the diagnosis of parotid gland tumors. Methods. We retrospectively reviewed charts of 129 patients who underwent parotidectomy for parotid lesions at Aga Khan University Hospital from 2002 to 2010. We compared the results of preoperative FNAC with final histopathological diagnosis. Results. Concordance with histological results was observed in 86%, specificity was 98%, sensitivity was 84%, and diagnostic accuracy was 94%. Conclusion. Our results demonstrate that preoperative cytology in parotid lesions is fairly accurate and useful in diagnosing benign from malignant and in planning appropriate approach for treatment. 1. Introduction A lump in the salivary gland region often presents as a diagnostic challenge with regards to its site of origin, benign or malignant. Most of these occur in the parotid glands; small percentages occur in the submandibular, sublingual, and minor salivary glands. Parotid gland lesions are a histologically diverse group. Tumors of this region comprise 3% of all head and neck and 0.6% of all tumors of human body [1]. The history of fine needle aspiration cytology (FNAC) goes back to the 1920s where it came into use simultaneously in Europe and the United states [2, 3]. FNAC is a cytodiagnostic method based on the morphological findings of individual cells, group of cells, and microparticles of tissue, acquired using a needle. The role of FNAC for the diagnosis of salivary gland masses is well documented. The traditional open biopsy is no longer justified because of the risk of tumor spillage and damage to the facial nerve [4]. The method has a high degree of sensitivity in distinguishing the tumors from nonneoplastic lesions of salivary gland [5, 6]. FNAC is an easily done procedure with minimal incidence of complication and no risk of implantation of tumor cells (<1%). The complications are rare and bleeding or inflammatory reaction in the region of the puncture. The impairment of the involved nerves has been reported as a very rare complication [7, 8]. FNAC has its proponents and opponents. It is regarded as a diagnostic procedure to be superior to the combination of physical examination and radiological evaluation [9, 10]. Many authors claimed that it is accurate, safe and cost
A comparative analysis of toluidine blue with frozen section in oral squamous cell carcinoma
Montasir Junaid, Moaz M Choudhary, Zain A Sobani, Ghulam Murtaza, Sadaf Qadeer, Naeem S Ali, Mumtaz J Khan, Anwar Suhail
World Journal of Surgical Oncology , 2012, DOI: 10.1186/1477-7819-10-57
Abstract: After obtaining clearance from the in-house ethical review committee, a prospective study was conducted at Aga Khan University Hospital, Karachi, from August 15, 2009 to March 14, 2010. A sample of 56 consenting patients with biopsy-proven OSCC were included in the study, giving us 280 tumor margins. Margins were analyzed using toluidine blue staining and frozen section histopathology. A receiver operator curve (ROC) was then applied to compare assessment of margin status by toluidine blue and frozen section.Of the 280 examined margins 11 stained positive with toluidine blue, three were positive on frozen section biopsy, and three were positive on final histopathology. Toluidine blue staining had sensitivity and specificity of 100% and 97%, respectively. The diagnostic accuracy of toluidine blue was found to be 97.1% with a positive predictive value (PPV) of 27.2% and a negative predictive value (NPV) of 100%.Toluidine blue can be used as an effective screening modality for the assessment of intraoperative margins in resource limited environments and reducing the number of frozen section biopsies performed. Further by providing real-time clinical information within minutes it can reduce indirect costs such as operating room time. It may also be used as an ad hoc for frozen section biopsies where frozen section facilities are available.When assessing the incidence and prevalence of cancers the International Agency for Research on Cancer, an arm of the World Health Organization (WHO), ranked head and neck cancers as the sixth most common malignancies in males [1]. Contributing to the same database, Bhurgri et al.; while reviewing their data from Karachi, Pakistan found a higher burden of disease [2]. In the local data, head and neck neoplasms accounted for the highest number of malignant neoplasm in males (age standardized rate (ASR) of 22.5 per 100,000) and the second highest number in females (ASR of 20.4 per 100,000) [2]. Given the prevalent cultural practices of c
Terahertz Generation in an Electrically Biased Optical Fiber: A Theoretical Investigation
Montasir Qasymeh
International Journal of Optics , 2012, DOI: 10.1155/2012/486849
Abstract: We propose and theoretically investigate a novel approach for generating terahertz (THz) radiation in a standard single-mode fiber. The optical fiber is mediated by an electrostatic field, which induces an effective second-order nonlinear susceptibility via the Kerr effect. The THz generation is based on difference frequency generation (DFG). A dispersive fiber Bragg grating (FBG) is utilized to phase match the two interacting optical carriers. A ring resonator is utilized to boost the optical intensities in the biased optical fiber. A mathematical model is developed which is supported by a numerical analysis and simulations. It is shown that a wide spectrum of a tunable THz radiation can be generated, providing a proper design of the FBG and the optical carriers. 1. Introduction Due to a lack of generation and detection instrumentation, the electromagnetic spectrum between infrared light and microwave radiation, traditionally known as the terahertz (THz) gap, has not been fully explored [1]. The application of THz radiation was traditionally limited to astronomy and analytical science. Recent advances in photonics have laid the groundwork for the realization of THz sources and detectors for applications in biomedical imaging [2] and ultra-fast communications [3]. As THz sources become more readily available, THz technology is being increasingly used in a variety of fields, including information and communications technology, biology and medical sciences, nondestructive evaluation, homeland security, quality control of food and agriculture, global environmental monitoring, and ultrafast computing, to mention a few examples [4]. The wide and crucial applications of THz waves are due to its unique way of interacting with materials. For example, in medical science, the ability of THz wave to probe intermolecular interactions enables it to provide both structural and functional information. Consequently, and considering its safe, accurate, and economical features, THz radiation promisesto alternate other scanning methods such as high frequency ultrasound, magnetic resonance imaging, and near-infrared imaging [4]. This promising technology has the potential to lead the way many diseases are diagnosed and ultimately cured. In the past few years, several techniques have been proposed to generate THz waves. Generation of CW and pulsed THz waves have been both investigated. Techniques to generate CW THz waves include quantum cascade laser (QCL) [5], directly multiplied source [6], backward wave oscillator (BWO) [7], germanium laser [8], and silicon impurity
Classification Using Two Layer Neural Network Back Propagation Algorithm  [PDF]
K. A. Mohamed Junaid
Circuits and Systems (CS) , 2016, DOI: 10.4236/cs.2016.78104
Abstract: Worldwide breast cancer is the most common form of cancer death occurring in 12.6% of women. This paper presents a cost effective approach to classify the normal, malignant and benign tumor using two layer neural network back propagation algorithm. Back propagation algorithm is used to train the neural network. Parallelization techniques speed up the computation process and as a result two layer neural networks outperform the previous work in terms of accuracy. Breast cancer tumor database used for the testing purpose is from the CIA machine learning repository. The highest accuracy of 97.12% is achieved using the two layer neural network back propagation algorithm.
Measuring Religiosity and Workplace Spirituality in Pakistan: a Case Study of Armed Forces and University Teachers
Junaid Zafar
Cross-Cultural Communication , 2010, DOI: 10.3968/990
Abstract: The article reviews workplace spirituality that began as a grass-root movement and has now become a philosophy used to better management in achieving its organizational goals. The concept however is still strange to countries like Pakistan which are swamped with ignorance and business myopia.The article finds out the extent to which the sectors like Pak. Army and Teaching are experiencing religiosity and workplace spirituality. For this, individuals have been selected from different age groups and positions and case study methodology has been implemented. The study finds out that both sectors experience spirituality and religiosity more or less to a certain extent but at the same time fail to identify any organization where workplace spirituality is being followed in letter and spirit. Key words: Religion; Workplace SpiritualityResumé: L'article passe en revue la spiritualité en milieu de travail en tant qu'un mouvement de base et elle est devenue maitenant une philosophie utilisée pour une meilleure gestion dans la réalisation de ses objectifs organisationnels. Le concept est cependant toujours inaccoutumé à des pays comme le Pakistan qui sont submergés par l'ignorance et la myopie des affaires.L'article decouvre l'ampleur dans laquelle les secteurs comme les Armées pakistanaise et l'enseignement connaissent la religiosité et la spiritualité en milieu de travail. Pour cela, des individus ont été choisis parmi des groupes d'age et de position différents et une méthodologie de l'étude de cas a été mise en uvre. L'étude conclut que les deux secteurs ont plus ou moins d'expérience de la spiritualité et de la religiosité dans une certaine mesure, mais en même temps, elle ne peut pas identifier aucune organisation où la spiritualité en milieu de travail est suivie littérallement ou spirituellement.Mots-clés: religion; spiritualité en milieu de travail
Human Resource Management Practices at Work in Third World Countries:
Junaid Zafar
Management Science and Engineering , 2010,
Abstract: Human resource management is a component of every manager’s job tasks. These responsibilities include placing the right people in the right time and at the right task. The employees then have to be polished through orienting, training and compensating to improve his or her job performance. The paper will discover the Human Resource Management Practices at work and will put forth some recommendations that I have found lacking during visit to the plant. KAPCO is one of the well known organizations of Pakistan. It was established in 1984 by the collaboration of International and National efforts. Company has a well organized working structure. It has an unbiased recruitment and selection process. The policies and procedures are made with mutual consent of Top, Middle and Lower level management. Employees’ personal records are maintained very well, with each employee having his/her own KAPCO’s identity cards, medical cards etc for recognition. Unionization is very strong at KAPCO with two unions running side by side for employees’ rights. For severe type of misconduct inquiries are held and penalties are charged accordingly. Employees are provided with accommodation facilities. Transport, Medical, Education, Messing, Banking, Shopping complex facilities are provided within the premises of KAPCO. Keywords: Human Resource Management; Corporate Social Responsibility
Human Resource Management Practices at Work in Third World Countries: A Case Study of Kot Addu Power Company (KAPCO)
Junaid Zafar
Management Science and Engineering , 2010,
Abstract: Human resource management is a component of every manager’s job tasks. These responsibilities include placing the right people in the right time and at the right task. The employees then have to be polished through orienting, training and compensating to improve his or her job performance. The paper will discover the Human Resource Management Practices at work and will put forth some recommendations that I have found lacking during visit to the plant. KAPCO is one of the well known organizations of Pakistan. It was established in 1984 by the collaboration of International and National efforts. Company has a well organized working structure. It has an unbiased recruitment and selection process. The policies and procedures are made with mutual consent of Top, Middle and Lower level management. Employees’ personal records are maintained very well, with each employee having his/her own KAPCO’s identity cards, medical cards etc for recognition. Unionization is very strong at KAPCO with two unions running side by side for employees’ rights. For severe type of misconduct inquiries are held and penalties are charged accordingly. Employees are provided with accommodation facilities. Transport, Medical, Education, Messing, Banking, Shopping complex facilities are provided within the premises of KAPCO.
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