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Search Results: 1 - 10 of 5243 matches for " Mohammed Rayis "
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Neuroblastoma in Saudi Children: A Single Center Experience (2006-2014)  [PDF]
Zaid Al Naqib, Atif A. Ahmed, Musa Al Harbi, Fahad Al Manjomi, Zaheer Ullah Khan, Awatif Alanazi, Othman Mosleh, Walid Ballourah, Mohammed Rayis
Journal of Cancer Therapy (JCT) , 2015, DOI: 10.4236/jct.2015.610098
Abstract: Introduction: Neuroblastoma is the most common extracranial solid tumor in childhood and survival rate has improved during the last few decades. Only a few studies, related to Neuroblastoma in Saudi Arabian children, have been performed. We report epidemiologic data and our clinical experience from the department of Pediatric Hematology Oncology (PHO), King Fahad Medical City (KFMC), Riyadh, Saudi Arabia. Method: A retrospective observational study of all patients, with diagnosis of Neuroblastoma, who attended PHO-KFMC from July 2006 to June 2014 was performed. The survival periods (overall survival and disease-free survival) and the final outcomes for patients treated and followed at KFMC were recorded. The survival data were statistically correlated with the clinical, pathological and biological features of patients and tumors and compared to national and international cohorts. Results: Eight-year data were available for the 42 patients of which 22 (52.4%) were male and 20 (47.6%) were females. Age at diagnosis ranged 0 - 91 months with a mean and median of 26.3 and 18.5 months respectively. 16 (38.1%) patients were under one year and 26 (61.9%) above 1 year of age. The event-free survival (EFS) and overall survival (OS) rates were 66.5% and 71.5% respectively. EFS and OS among those who were <1 year age at presentation was 75% and 82%, whereas ≥1 yr age group had 59% and 62% survival rates respectively. Patients with tumors in the adrenal had considerably lower EFS (59%) and OS (63%); in comparison to patients with tumors sites other than the adrenal who had EFS and OS of 85% and 89% respectively. Both EFS and OS survival rates at the end of follow-up interval were 100.0%, in the low and intermediate risk groups. In contrast, patients in the high risk group had EFS and OS rates of 44% and 48% respectively. This difference was statistically significant (p < 0.05). Conclusion: Our results are very encouraging and comparable with known published international cohorts, and reveal an excellent outcome for stage 1, 2, 3 & 4 s. The prognosis for advanced (stage 4) disease remains rather poor. A collaborative Saudi-wide effort, with an emphasis on research in detecting clinical and biologic characteristics of aggressive disease and tailoring therapy, is needed.
Pediatric Non-Hodgkin Lymphoma: A Retrospective 7-Year Experience in Children & Adolescents with Non-Hodgkin Lymphoma Treated in King Fahad Medical City (KFMC)  [PDF]
Nahla Ali Mobark, Suha A. Tashkandi, Wafa Al Shakweer, Khalid Al Saidi, Suha A. Fataftah, Mohammed M. Al Nemer, Awatif Alanazi, Mohammed Rayis, Walid Ballourah, Othman Mosleh, Zaheer Ullah, Fahad El Manjomi, Musa Al Harbi
Journal of Cancer Therapy (JCT) , 2015, DOI: 10.4236/jct.2015.64033
Abstract:

Background: Non-Hodgkin’s lymphoma is an aggressive malignant disease in children and adolescents. Although it is the fourth most common malignancy in Saudi children as reported in Saudi cancer registry, less information is available about pediatric Non-Hodgkin lymphoma and its outcome in Saudi Arabia. Study Objectives: To provide demographic data, disease characteristics, treatment protocol, toxicity and outcome of treatment in children & adolescents with Non-Hodgkin’s lymphoma treated at KFMC. This study will form base line for future studies about pediatric Non-Hodgkin’s lymphoma in KFMC, which may help to improve outcome for children with cancer in Saudi Arabia. Study Patients and Method: We retrospectively analyzed 28 children and adolescents diagnosed to have Non-Hodgkin’s lymphoma at KFMC between December 2006 and December 2013, followed-up through June 2014. Results: Of the 28 patients, 10 (35.7%) girls and 18 (64.3%) boys, the male-to-female ratio was 1.8; 1. The median age at time of diagnosis was 6.4 years old (range 2.0 to 13.0 years old). The majority of patients (64.3%) were aged between 5 and 12 years old. Burkitt’s lymphoma BL/BLL was the most common pathological subtype (60.7%), and DLBCL was the second most common subtype (21.4%). Abdominal and Retroperitoneal involvement was the most common primary site (78.6%) including the ileocaecal region. Most of the children presented with advanced Stage III and IV (75%), Cytogenetic study which screens specifically for the t (8; 14) (q24; q32) a characteristic genetic feature of Burkitt’s Lymphoma was obtained from 21 patients, variant rearrangement was observed in 3/21 samples and complex chromosomes karyotype in addition to IGH/MYC rearrangement was observed in 2/21 samples. Those patients presented with very aggressive lymphoma and combined BM and CNS involvement. We use the French-American-British Mature B-Cell Lymphoma 96 Protocol (FAB LMB 96) for treatment fornewly diagnosed Mature B-Cell type NHL and high risk ALL CCG 1961 Protocol for lymphoblastic lymphoma and international Anaplastic Large Cell Lymphoma 99 Study Protocol for ALCL. The median follow-up in patients not experiencing an adverse event was 53.1 months. The estimated 3-year EFE and OS rates in the entire cohort of patients with newly diagnosed NHL treated in the KFMC were 85.2% and 89.2% respectively; Overall survival (OS) rate of patients with mature

Correlation of Endoscopic Findings with Various Helicobacter pylori Tests among Dyspeptic Patients  [PDF]
Mohammed O. Mohammed
International Journal of Clinical Medicine (IJCM) , 2014, DOI: 10.4236/ijcm.2014.519151
Abstract: Background: Helicobacter pylori is the most common chronic bacterial infection, and a significant etiological factor in acid peptic diseases and gastric cancer. Dyspepsia is a common gastrointestinal disorder, and the most common indication for gastroscopy. Detection of H. pylori during endoscopy has become standard clinical practice. Elevated levels of inflammatory markers such as C-reactive protein (CRP), are associated with pathological changes, and hence give useful information for exact diagnosis and therapy. Objectives: To determine the relationship between endoscopic findings, highly sensitive C-reactive protein level (hs-CRP) and H. pylori infection among dyspeptic patients using serological tests, stool antigen for H. pylori and antral histology. Methods: This was a prospective study; patients with dyspepsia, who referred to Kurdistan Teaching Center of Gastroenterology & Hepatology in Sulaimani City were assessed, during the period of December 2012 to March 2014. They underwent gastroscopy, and biopsies were taken from the corpus and antral portions of antral portion for histopathological exam. Patients’ serum samples were tested for H. pylori infection using ELISA method to detect (IgG & IgA) anti-bodies and stool samples were examined using rapid immunoassay method to detect H. pylori antigens. hs-CRP was assessed using ELISA. Results: One hundred dyspeptic patients were included in the study. The mean age was 34.2 years and male comprised 54% of the study samples. The common findings in oesophagogastroduodenoscopy (OGD) examination were antral gastropathy (59%) and duodenal ulcer (21%). A statistically significant (P < 0.01) correlation was found between hs-CRP and H. pylori IgG and IgA levels (titer). There was a highly significant (P < 0.01) correlation between the level of H. pylori IgG and the endoscopic findings. The highest serum level of H. pylori IgG was found in duodenal ulcer and antral gastritis, (88.86 ± 42.0) and (70.05 ± 35.2) Au/ml, respectively. There was a highly significant correlation (P < 0.01) between endoscopic findings and H. pylori positive antral biopsy, in duodenal ulcer, antral gastritis and duodenitis was 100%, 94.9% and 75% respectively. Also duodenal ulcer and antral gastritis showed high mean and percentage but no significant differences in both H. pylori IgA and stool Antigen.
PLOJDY ANALYSIS AND DNA CONTENT OF MUTANT BANANA
ABDELGADIR RAYIS SHADIA,ROFINA YASMIN OTHMAN,MAK CHAI
BIOTROPIA : the Southeast Asian Journal of Tropical Biology , 2002,
Abstract: Mutagens cause random changes in the nuclear DNA or cytoplasmic organelles, resulting in gene, chromosomal or genomic mutations and hence, create variability. In this study, flow cytometry (FCM) was used to determine ploidy levels and DNA content in gamma-irradiated variants of mutated Pisang Berangan (cv. Intan, AAA) - a local banana genotype. Induced variants such as shor t plant stature (stunted growth), late flowering plants (late maturity) and abnormalities in bunch characters were selected to stud y possible changes at the DNA level. The study showed that DNA content of mutated plants differed from non-irradiated control and that irradiation had the most effect at high doses (40 and 60 Gy). The increase of DNA content in 20 Gy and 30 Gy treated plants was not more than that of the control plants. The values of genomic DNA content of gamma-irra diation variants decreased as the dose of irradiation increased from 20 to 60 Gy, indicating that the high dose of gamma-irradiation had a significant effect on the genome of the plants. The analysis further showed that phenotypic variation due to mutagenesis was reflected in the DNA content of the plants. The results also showed that ploidy levels were not affected by gamma-irradiation even at high doses.
General Periodic Boundary Value Problem for Systems  [PDF]
Mohammed Elnagi
Applied Mathematics (AM) , 2012, DOI: 10.4236/am.2012.38130
Abstract: The paper deals with the existence of nonzero periodic solution of systems, where k∈(0, π/T), α, β are n×n real nonsingular matrices, μ=(μ1…μn), f(t, u)=(f1(t, u),…,fn(t, u))∈C([0, T]×□n+,□+) is periodic of period T in the t variable are continuous and nonnegative functions. We determine the Green’s function and prove that the existence of nonzero periodic positive solutions if one of . In addition, if all i=(1…n)where λ1 is the principle eigenvalues of the corresponding linear systems. The proof based on the fixed point index theorem in cones. Application of our result is given to such systems with specific nonlinearities.
Pseudocercospora leaf and fruit spot disease of citrus: Achievements and challenges in the citrus industry: A review  [PDF]
Mohammed Yesuf
Agricultural Sciences (AS) , 2013, DOI: 10.4236/as.2013.47046
Abstract:

Citruses are the worlds’ second fruit crops by volume next to banana. It is one of the most important commodity in tropical Africa as source of foreign currency, raw material for agro-industries and source of employment. The production and productivity of citrus in tropical Africa including Ethiopia are critically threatened by a number of diseases. Among others, pseudocercospora leaf and fruit spot of citrus caused by a fungus Pseudocercospora angolensis is the most destructive disease of citrus. Literature reviews have been made by searching the available information on leaf and fruit spot of citrus. Journal articles, research papers, workshop proceedings, Thesis research, manuals, and quarantine regulations were among the information sources of the review. The disease is widespread in 22 African countries including Ethiopia with a single report around Yemen in the Arabian Peninsula. Scattered research efforts have been made by different researchers in Africa mainly dealing with its geographic distribution, biology, and management practices. Fungicides, plant extracts/essential oils, and host resistance are among the research efforts made for the control of P. angolensis. Even though the disease is not yet reported to the rest of the world, it becomes a serious concern as an important quarantine pest thereby critically affecting the world trade and germplasm exchange of the citrus industry. Therefore, the purpose of this paper is to compile the scattered information on various aspects of leaf and fruit spot of citrus mainly to avail the information for researchers, development workers and policy people. Moreover, this review will suggest future research and development direction towards better understanding and sustainable management practices of the disease.

Variation of the Spectrum of Operators in Infinite Dimensional Spaces  [PDF]
Mohammed Yahdi
Advances in Pure Mathematics (APM) , 2013, DOI: 10.4236/apm.2013.37080
Abstract:

The paper investigates the variation of the spectrum of operators in infinite dimensional Banach spaces. Consider the space of bounded operators on a separable Banach space when equipped with the strong operator topology, and the Polish space of compact subsets of the closed unit disc of the complex plane when equipped with the Hausdorff topology. Then, it is shown that the unit spectrum function is Borel from the space of bounded operators into the Polish space of compact subsets of the closed unit disc. Alternative results are given when other topologies are used.

A New Expression for Rhotrix  [PDF]
Abdul Mohammed
Advances in Linear Algebra & Matrix Theory (ALAMT) , 2014, DOI: 10.4236/alamt.2014.42011
Abstract:
This paper presents a new technique for expressing rhotrices in a generalize form. The method involves using multiple array indexes as analogous to matrix expressions, unlike the earlier method in the literature, which can only be functional in a single array computational environment. The new rhotrix look will encourage the study of rhotrix algebra and analysis from a better perspective. In addition, computing efficiency and accuracy will also be improved, particularly when the operations in rhotrix space over the new expression are algorithmatized for computing machines.
Nature of Centennial Global Climate Change from Observational Records  [PDF]
Mohammed Anwer
American Journal of Climate Change (AJCC) , 2015, DOI: 10.4236/ajcc.2015.44027
Abstract: In order to provide a better benchmark for climate simulation programs, climate data at Global Historical Climatology Network (GHCN) and Global Summary of the Day (GSOD) archived by the National Climate Data Center (NCDC) are used to ascertain the nature of climate change over the last century. After data validation, about 6000 stations are considered globally to determine the change in mean temperature, and about 5000 stations to determine that change in maximum and minimum temperatures. Global nature of temperature and its change are presented separately for January and July. Both maximum and minimum daily temperatures are used in the analysis. Trend of global change in annual precipitation is also reported here. Least square linear regression is used to ascertain the nature of these changes. Global nature of temperatures in both January and July show bimodal distributions, with the geographical region between the tropics in one mode and the region outside the tropic in another mode. The individual distributions of temperatures of both these regions show separate and similar histograms. Results indicate that over the last century, temperature in January increased more than that during July. Furthermore the minimum temperature in each case increased more than the maximum temperature. Ten separate estimates of temperature change are obtained from the data presented here using different methods. Considering all these estimates, the mean rise in temperature during January was 2.19°C, and during July was 1.72°C. The geographical nature of the rise in temperature shows that though it rises in most locations, the temperature also reduces along eastern Asia, some parts of central Russia, along south-eastern Australia, and along the east coast of the United States. Predominant rise in temperature is mostly over Europe, and in the arctic. Change in precipitation shows that though there is significant reduction rainfall globally, rainfall increases along the equator, in areas around the Gulf of Mexico, along eastern Asia, along the western coast of India, and along the eastern coast of Australia.
Performance of Heat Pipe Utilized for Atmospheric Air Heating  [PDF]
Mohammed Mansur
Journal of Applied Mathematics and Physics (JAMP) , 2015, DOI: 10.4236/jamp.2015.38125
Abstract:

The objective of the present experimental work is to investigate the performance of a wrapped screen heat pipe for atmospheric air heating to compare with the limits of this pipe. The experiment was conducted using copper pipe material and acetone as working fluid at different vapor temperatures. The testing also consists of a heater, a blower for heat removal (condenser), temperature measuring device, a vapor temperature probe, acetone charging system, and a vacuum pump. The copper outside diameterof the pipe is 0.022 m, with a total length of 0.6 m. The results showed that the pipe wall temperature (Tw) for a wrapped screen heat pipe has a rapid increase and takes 50 min to reach steady state at (Q = 63 W). The vapour temperature of working fluid increases as the heat load increases at constant air velocity. It was also been found that the range of vapour temperature deceases as the filling ratio increases that means the increasing of the filling ratio results the decrease of the maximum vapour temperature and the variation in the vapour temperature. The best recorded filling ratio is 0.6 which has the lowest vapour temperature at highest heat load. The maximum heat transport limit for this pipe is 80 W and the maximum temperature difference for air is 5C.

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