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Search Results: 1 - 10 of 352473 matches for " Mohammad S. Al-Zoubaidi "
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Treatment of Basal Cell Carcinoma by Topical 25% Podophyllin Solution  [PDF]
Khalifa E. Sharquie, Adil A. Noaimi, Mohammad S. Al-Zoubaidi
Journal of Cosmetics, Dermatological Sciences and Applications (JCDSA) , 2015, DOI: 10.4236/jcdsa.2015.53023
Abstract: Background: Basal cell carcinoma is the most common malignancies of the skin. Numerous modalities of treatment are available. Podophyllin is an antimitotic and caustic agent that has been used in treatment of genital warts. Objective: To test the effectiveness and safety of topical 25% podophyllin in treatment of basal cell carcinoma. Patients and Methods: Thirty eight patients with basal cell carcinoma enrolled in this open labeled interventional study that had been enrolled in Department of Dermatology-Baghdad Teaching Hospital, Baghdad, from January 2010 to October 2011. History and physical examination was performed to all patients regarding all demographics detail related to the disease. Exclusion criteria: were pregnancy, recurrent tumors, aggressive deep subtypes, morpheaic type, and size more than 2 cm2 in diameter. Biopsies for all patients were done for histopathological examination at the first visit, and after clinical cure of the lesions. Lesions were treated with 25% topical podophyllin solution once weekly for 6 weeks. Follow up after clinical cured was done every 3 months up to 18 months to recording any sign and symptom of recurrent. Results: Thirty five patients with basal cell carcinoma completed the study: 28 (80%) males and 7(20%) females with males to females ratio 4:1, their ages ranged from 30 - 87 (64.114 ± 12.68) years, and the duration of the disease ranged from 2 months to 30 years (6.88. ± 4.83) years. The size of lesions ranged from 0.8 - 1.9 (1.454 ± 0.239) cm. The total podophyllin applications number ranged from 2 - 6 (4.65 ± 1.055) sessions. The total numbers of treated lesions were 100 lesions: 64 (64%) nodular, 31(31%) pigmented, 3(3%) Basosquamous, and 2 (2%) superficial. Ninety six (96%) lesions in 32 patients showed complete cure with 2 - 6 sessions, while 4 lesions in 3 patients showed partial response with 6 sessions. Biopsy from 21 cured lesions in 21 patients showed complete clearness apart from one with residual malignant cells. All the patients did not show clinical recurrence, during the follow up period up to 18 months. Inflammatory
A New Chaotic Behavior from Lorenz and Rossler Systems and Its Electronic Circuit Implementation  [PDF]
Qais H. Alsafasfeh, Mohammad S. Al-Arni
Circuits and Systems (CS) , 2011, DOI: 10.4236/cs.2011.22015
Abstract: This paper presents a new three-dimensional continuous autonomous chaotic system with ten terms and three quadratic nonlinearities. The new system contains five variational parameters and exhibits Lorenz and Rossler like attractors in numerical simulations. The basic dynamical properties of the new system are analyzed by means of equilibrium points, eigenvalue structures. Some of the basic dynamic behavior of the system is explored further investigation in the Lyapunov Exponent. The new system examined in Matlab-Simulink and Orcad-PSpice. An electronic circuit realization of the proposed system is presented using analog electronic elements such as capacitors, resistors, operational amplifiers and multipliers.
Determination of Antibiotic Drug Cefdinir in Human Plasma Using Liquid Chromatography Tandem Mass Spectroscopy  [PDF]
Mohammad A. Al Bayyari, Raed S. Abu Ajjour
American Journal of Analytical Chemistry (AJAC) , 2015, DOI: 10.4236/ajac.2015.63022

The following article has been retracted due to the investigation of complaints received against it. The Editorial Board found that there are conflicts of interests between the authors and their organization. The scientific community takes a very strong view on this matter, and the American Journal of Analytical Chemistry treats all unethical behavior seriously. This paper published in Vol. 6 No. 3 239-254, 2015 has been removed from this site.

Title: Determination of Antibiotic Drug Cefdinir in Human Plasma Using Liquid Chromatography Tandem Mass Spectroscopy

Author: Mohammad A. Al Bayyari, Raed S. Abu Ajjour
Selenium Nanoparticles Ameliorative Effect on Acetaminophen Hepatotoxicity in Male Mice  [PDF]
Mohammad S. AL-Harbi, Sayed A. M. Amer
Natural Science (NS) , 2017, DOI: 10.4236/ns.2017.97020
Abstract: Selenium nanoparticles (SeNPs) have been widely used as anti-inflammatory and anti-toxic agent. The present study used Bacillus tequilensis for biosynthesizing SeNPs from sodium selenite (Na2SeO3) and investigated its ameliorative effects on acetaminophen (APAP) hepatotoxicity in male mice. The results indicated that Alanine transaminase (ALT), aspartate aminotransferase (AST) and alkaline phosphatase (ALP) significantly elevated in mice treated with APAP, while other liver markers (total proteins and albumin) did not change. SeNPs either alone or in combination with APAP showed ameliorative effects on liver enzymes to some extents where their activities decreased to be insignificant with those of normal group. A slight variation was shown in total antioxidant capacity (TAC). Histopathologically, the hepatocytes of the mice treated with APAP showed cloudy swelling and vacuolar degeneration, while those treated with SeNPs or both SeNPs and APAP appeared more or less histologically normal. In conclusion, SeNPs can be used to improve or replace today’s therapies of APAP hepatotoxicity.
Subcision in the Treatment of Acne Scar in Iraqi Patients  [PDF]
Hayder R. Al-Hammamy, Abd-Allah S. Mohammad, Ihsan A. Al-Turfy
Journal of Cosmetics, Dermatological Sciences and Applications (JCDSA) , 2015, DOI: 10.4236/jcdsa.2015.52015
Abstract: Background: Acne vulgaris is a very common skin disease among young people which might be associated with scarring that has a great impact on the emotional, psychological and social life of the patients as it will go with them for life. Subcision is a new technique for the treatment of acne scars. Objective: To assess objectively and subjectively the efficacy and safety of subcision in the treatment of depressed acne scars. Patients and Methods: This is an open-label therapeutic trial. A total of 16 patients were enrolled in this study. Twelve were males and 4 were females. Their ages ranged from 19 - 39 with a mean of 26.64 ± 5.64. The duration of scar varied between 6 months and 10 years with a mean of 4.14 ± 2.54 years. subcision was done by introducing a sterile, hypodermic, 18-gauge needle. The needle was held by a three ml syringe for better orientation of the sharp tip of the needle. It was kept horizontal to the skin surface with the bevel up, and was introduced in a high sub dermal plane. The needle was slowly advanced parallel to the skin surface. Initially, rapid, repetitive linear back-and-forth motion of the needle makes the skin free of the underlying scar. This procedure was repeated in all directions in a fan-like manner. Results: According to Modified Sharquies scoring system for grading acne scars, 4 (25%) patients had severe grade, 11 (68.8%) patients had moderate grade and only 1 (6.2%) patient had mild grade. Evaluation at 6 months after treatment revealed that 8 (50%) patients had mild acne scar, 7 (43.8%) had moderate acne scar and only 1 (6.2%) patient still had severe grade. This change in the grades was statistically significant (p-value = 0.01713441). The average score before treatment was 13.13 ± 2.363; it became 9.50 ± 2.944 after 6 months. By paired t-test comparison, the difference in the score was statistically highly significant (p = 0.000044). Regarding the photographic assessment, the difference in the visual analogue scale before and after treatment was statistically significant (p-value = 0.043823). All patients were satisfied regarding subcision as treatment for their acne scars with variable degrees. In general the reported side effects were transient and vanished within 3 - 7 days apart from firm bumps which resolved within 12 weeks in all patients. Conclusion: Sub
Leachability of Oil Shale Ash from Isfir Al-Mahata Oil Shale, Southern Jordan  [PDF]
Hani M. Alnawafleh, Mohammad S. Al-Harahsheh, Adnan M. Al-Harahsheh
Journal of Minerals and Materials Characterization and Engineering (JMMCE) , 2016, DOI: 10.4236/jmmce.2016.45026
Abstract: This paper presents the first study on the oil shale (OS) ashing and OS ash leachability of Jordanian OS located further in the south. The studied OS is from Isfir Al-Mahata subsurface OS located 10 km south of Ma’an. Chemical and physical characterization of the OS ash was performed and compared with original OS. Ashing OS was conducted at different temperatures. Important parameters affecting OS ash leachability were also investigated. The leachability of certain heavy metals was investigated based on clear leaching protocol. The Fisher Assay analysis result indicates that this OS type has quite higher moisture content, lower oil content, and higher spent shale compared with other Jordanian oil shales. Ashing of OS at higher temperatures (950°C) resulted in the disappearance of silica, due to its complete reaction with lime and Al, and formation of Anhydrite and cement materials like, Portland cement. The leachability analysis indicates that for most elements the leachability is high at low pH. The released heavy metals concentrations are below EPA limits. Chromium and lead are leached out more than other elements with the exception at low pH. In general, the higher the ashing temperature is, the lower the release of elements is. The chemical composition of the ash and the leachability results suggests that it has high fixing capacity toward the heavy metals present in the ash.
Familial Eosinophilic Granulomatosis with Polyangiitis  [PDF]
Abdurhman S. Al Arfaj, Mohammad Al Anazi, Najma Khalil, Akbar Ali Khan Pathan, Narsimha Reddy Parine
Open Journal of Rheumatology and Autoimmune Diseases (OJRA) , 2017, DOI: 10.4236/ojra.2017.73013
Abstract: Eosinophilic granulomatosis with polyangiitis (EGPA) is an uncommon ANCA associated vasculitic disorder characterized by systemic necrotizing vasculitis of small vessels occurring exclusively among patients with bronchial asthma and tissue eosinophilia. Familial EGPA is extremely rare. Only two case reports have been published so far. We present a Saudi family with 3 cases of EGPA and almost three-fourths of family members affected by asthma. We explored genetic basis of EGPA in this family and found that genes were mutated in four affected siblings suggesting genetic involvement in susceptibility to EGPA.
Assessment of Heavy Metals Pollution in the Sediments of Euphrates River, Iraq  [PDF]
Emad A. Mohammad Salah, Tahseen A. Zaidan, Ahmed S. Al-Rawi
Journal of Water Resource and Protection (JWARP) , 2012, DOI: 10.4236/jwarp.2012.412117
Abstract: Fourteen bed sediments samples were collected from the Euphrates River in order to determine concentrations, seasonal, spatial and contamination assessment of heavy metals such as Pb, Cd, Zn, Cu, Ni, Co, Fe, Mn and Cr. The mean concentrations are as follows: 2249.47 mg/kg for Fe, 228.18 mg/kg for Mn, 67.08 mg/kg for Ni, 58.4 mg/kg for Cr, 48.00 mg/kg for Zn, 28.16 mg/kg for Co, 22.56 mg/kg for Pb, 18.91 mg/kg for Cu and 1.87 mg/kg for Cd. To assess metal contamination in sediments, sediment quality guidelines were applied. The mean concentration of Cd, Cu, Ni, Fe, Mn, and Cr exceeded the USEPA guideline. The metal contamination in the sediments was also evaluated by appling enrichment factor (EF), contamination factor (CF), geo-accumulation index (Igeo) and pollution load index (PLI). Based on enrichment factor (EF), the Euphrates River sediments have very high enrichment for Pb, extremely high for Cd, moderate for Zn, significant to very high for Ni, very high to extremely high for Co, moderate to significant for Mn and significant to very high for Cr. According to contamination factor (CF), Cd and Cr are responsible for very high contamination. According to Igeo, the Euphrates River sediments are moderately to strongly polluted by Cd. Based on PLI, all sampling sites suggest no overall pollution of site quality.
Depression in patients with colorectal cancer
Mohammad G. Sehlo,Mahmoud S. Al Ahwal
Saudi Medical Journal , 2013,
Abstract: Patients with colorectal cancer (CRC) experience psychological stress due to the diagnosis and the physical and social changes brought on by the illness, increasing the risk of depressive disorder. Depression causes tremendous disability and adds to the suffering that patients must already endure. It is known to alter immune and endocrine functions that affect vulnerability to CRC, its course over time, and its response to treatment. We review the prevalence of depressive symptoms and disorders worldwide and in the Kingdom of Saudi Arabia (KSA), focusing on patients with medical illness and those with CRC, in particular. We examine how often depression is diagnosed, how it is treated, and its likely course over time, and review the effects of depression on functional disability, longevity, and immune functions. Finally, we discuss research needs and make recommendations on highest priority research studies to advance our understanding of depressive disorder in CRC patients in KSA.
Abscisic Acid Effects on Maize (Zea mays L.) Embryo Culture
Dhia S. Hassawi,Mohammad Al-Nsour
Journal of Agronomy , 2007,
Abstract: Immature embryos of maize (Zea mays L.) were aseptically excised and cultured on Murashige and Skoog (MS) media containing four different Abscisic Acid (ABA) concentrations (Control 0.0, 0.1, 1.0 and 10.0 mg L-1). The ABA effects on the germination of cultured embryos, number of leaves per plant, plant height, percentage of dry matter and protein expression for plants regenerated from ABA treated embryos were studied. Effects of ABA on germinating embryos were found to be associated with time; it reduced the germination during the first week. ABA affected the percentage of dry matter significantly.
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