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Search Results: 1 - 10 of 837 matches for " Minoru Matsuno "
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Synthesis of Chiral Schiff Base Metal Complex Inducing CD and Elucidation of Structure of Adsorption on Surface of Gold Nanoparticles  [PDF]
Minako Oshima, Minoru Matsuno, Tsutsumi Yuki, Sunaga Nobumitsu, Tomoyuki Haraguchi, Takashiro Akitsu
International Journal of Organic Chemistry (IJOC) , 2017, DOI: 10.4236/ijoc.2017.72013
Abstract: We have prepared supramolecular systems of chiral Schiff base Ni(II), Cu(II), Zn(II) complexes and colloidal gold nanoparticles (AuNP) of 10 nm diameters. They demonstrated that direct adsorption of chiral Schiff base metal complex on the surface of AuNP owing to observation of clear induced CD spectra for the first time. We observed and discussed induced CD bands on AuNP from chiral Schiff base Ni(II), Cu(II), Zn(II) complexes.
Adoptability of Peer Assessment in ESL Classroom  [PDF]
Sumie Matsuno
Creative Education (CE) , 2017, DOI: 10.4236/ce.2017.88091
Abstract:
In ESL class, a teacher in charge of the class usually evaluates all the students’ performances, where using peer assessment may be a good way to confirm or modify the teacher assessment. In this study, whether peer assessment can be adopted in class is considered using FACET analysis. Since this is a regular small English class in Japan, the participants are 18 ESL university students and one teacher. First, one misfitting rater is eliminated and all the other raters including the teacher are included as assessors. The rater measurement report shows that, after eliminating one rater, no raters are misfits. The FACET map shows that most of them, including the teacher, are lenient raters. In addition, only a few unexpected responses are detected. Overall, this study concludes that peer assessment can be reasonably used as additional assessment in class.
Minimum Wage, Public Investment, Economic Growth  [PDF]
Minoru Watanabe
Theoretical Economics Letters (TEL) , 2013, DOI: 10.4236/tel.2013.35048
Abstract: This paper considers the relationship between economic growth and minimum wage. Minimum wage helps reduce poverty and maintain a minimum standard of living. However, it is also claimed that minimum wage has a negative effect on employment and GDP. This paper develops a simple two-period overlapping generation model with three economic policies, minimum wage, unemployment benefit, and public investment that improves labor productivity. The government imposes tax on firms to finance public capital and unemployment benefit under a balanced budget. We show that economic growth is promoted with an increase in minimum wage and the ratio of public investment to tax revenue.
Drosophila Carrying Pex3 or Pex16 Mutations Are Models of Zellweger Syndrome That Reflect Its Symptoms Associated with the Absence of Peroxisomes
Minoru Nakayama, Hiroyasu Sato, Takayuki Okuda, Nao Fujisawa, Nozomu Kono, Hiroyuki Arai, Emiko Suzuki, Masato Umeda, Hiroyuki O. Ishikawa, Kenji Matsuno
PLOS ONE , 2011, DOI: 10.1371/journal.pone.0022984
Abstract: The peroxisome biogenesis disorders (PBDs) are currently difficult-to-treat multiple-organ dysfunction disorders that result from the defective biogenesis of peroxisomes. Genes encoding Peroxins, which are required for peroxisome biogenesis or functions, are known causative genes of PBDs. The human peroxin genes PEX3 or PEX16 are required for peroxisomal membrane protein targeting, and their mutations cause Zellweger syndrome, a class of PBDs. Lack of understanding about the pathogenesis of Zellweger syndrome has hindered the development of effective treatments. Here, we developed potential Drosophila models for Zellweger syndrome, in which the Drosophila pex3 or pex16 gene was disrupted. As found in Zellweger syndrome patients, peroxisomes were not observed in the homozygous Drosophila pex3 mutant, which was larval lethal. However, the pex16 homozygote lacking its maternal contribution was viable and still maintained a small number of peroxisome-like granules, even though PEX16 is essential for the biosynthesis of peroxisomes in humans. These results suggest that the requirements for pex3 and pex16 in peroxisome biosynthesis in Drosophila are different, and the role of PEX16 orthologs may have diverged between mammals and Drosophila. The phenotypes of our Zellweger syndrome model flies, such as larval lethality in pex3, and reduced size, shortened longevity, locomotion defects, and abnormal lipid metabolisms in pex16, were reminiscent of symptoms of this disorder, although the Drosophila pex16 mutant does not recapitulate the infant death of Zellweger syndrome. Furthermore, pex16 mutants showed male-specific sterility that resulted from the arrest of spermatocyte maturation. pex16 expressed in somatic cyst cells but not germline cells had an essential role in the maturation of male germline cells, suggesting that peroxisome-dependent signals in somatic cyst cells could contribute to the progression of male germ-cell maturation. These potential Drosophila models for Zellweger syndrome should contribute to our understanding of its pathology.
When an Atom Becomes a Message—Practicing Experiments on the Origins of Life
Koichiro Matsuno
Information , 2012, DOI: 10.3390/info3030307
Abstract: Practicing experiments on the origins of life within the framework of quantum mechanics comes to face a task of distinguishing the descriptive spaces of the object between a space of physical states and a space of probability distributions. One candidate for accommodating both the physical and the probabilistic description in a mutually tolerable manner is to apply first-second person descriptions to the space of physical states while letting the space of probability distributions addressable in third person descriptions be accessible via first-second person descriptions. The mediator or messenger for accommodating these two types of description is the process of probability flow equilibration. The relative state formulation of quantum mechanics opens a possibility for the likelihood that a simple atom such as a carbon atom may carry a message for holding the process of probability flow equilibration. An experimental example demonstrating a carbon atom serving as a messenger is found in the running of the citric acid cycle in the absence of biological enzymes.
Receptive Openness to a Message and Its Dative—Materialist Origin of Time
Koichiro Matsuno
Information , 2011, DOI: 10.3390/info2030383
Abstract: Information precipitates the flow of time from scratch. Information as a noun, equivalent of the transitive verb “inform”, stands out in the contrast between a direct and an indirect object of the verb, that is to say, between the messenger of a message and its dative. The root of the contrast is sought in the occurrence of the flow of time in the sense that the flow requires both the invariant reference and the dative being subject to something flowing through against the reference. Empirical evidence of the contrast is found in the class identity kept by a molecular aggregate that can constantly exchange the constituent molecular subunits with those of a similar kind available in the neighborhood. The exchange of the subunits derives from the action of pulling-in, originating from the inside of the body holding the class identity. The action of pulling-in that underlies the synthesis of the flow of time empirically in a bottom-up manner originates in the constant update of the present perfect tense in the present progressive tense. The material aggregate preserving the class identity at the cost of the vicissitudes of the constituent individual subunits serves as the dative of information. The unfathomable depth of information is associated with the immense multitude of the messengers in their kinds toward the likely datives having the capacity of receiving them. The bottom line is that being informed is materially being receptive to a flow of substrate, so the information is being embodied by the receptor.
Drug-induced interstitial lung disease: mechanisms and best diagnostic approaches
Osamu Matsuno
Respiratory Research , 2012, DOI: 10.1186/1465-9921-13-39
Abstract: DILD can be difficult to diagnose; diagnosis is often possible by exclusion alone. Identifying the causative drug that induces an allergy or cytotoxicity is essential for preventing secondary reactions.One method to confirm the diagnosis of a drug-induced disease is re-exposure or re-test of the drug. However, clinicians are reluctant to place patients at further risk of illness, particularly in cases with severe drug-induced diseases. Assessment of cell-mediated immunity has recently increased, because verifying the presence or absence of drug-sensitized lymphocytes can aid in confirmation of drug-induced disease. Using peripheral blood samples from drug-allergic patients, the drug-induced lymphocyte stimulation test (DLST) and the leukocyte migration test (LMT) can detect the presence of drug-sensitized T cells. However, these tests do not have a definite role in the diagnosis of DILD. This study explores the potential of these new tests and other similar tests in the diagnosis of DILD and provides a review of the relevant literature on this topic.
Soliton and Periodic solutions of the Short Pulse Model Equation
Yoshimasa Matsuno
Physics , 2009,
Abstract: The short pulse (SP) equation is a novel model equation describing the propagation of ultra-short optical pulses in nonlinear media. This article reviews some recent results about the SP equation. In particular, we focus our attention on its exact solutions. By using a newly developed method of solution, we derive multisoliton solutions as well as 1-and 2-phase periodic solutions and investigate their properties.
The Peakon Limit of the N-Soliton Solution of the Camassa-Holm Equation
Yoshimasa Matsuno
Physics , 2007,
Abstract: We show that the analytic N-soliton solution of the Camassa-Holm (CH) shallow-water model equation converges to the nonanalytic N-peakon solution of the dispersionless CH equation when the dispersion parameter tends to zero. To demonstrate this, we develop a novel limiting procedure and apply it to the parametric representation for the N-soliton solution of the CH equaiton. In the process, we use Jacobi's formula for determinants as well as various identities among the Hankel determinants to facilitate the asymptotic analysis. We also provide a new representation of the N-peakon solution in terms of the Hankel determinants.
A direct method for solving the generalized sine-Gordon equation
Yoshimasa Matsuno
Physics , 2010, DOI: 10.1088/1751-8113/43/10/105204
Abstract: The generalized sine-Gordon (sG) equation was derived as an integrable generalization of the sG equation. In this paper, we develop a direct method for solving the generalized sG equation without recourse to the inverse scattering method. In particular, we construct multisoliton solutions in the form of parametric representation. We obtain a variety of solutions which include kinks, loop solitons and breathers. The properties of these olutions are investigated in detail. We find a novel type of solitons with a peculiar structure that the smaller soliton travels faster than the larger soliton. We also show that the short pulse equation describing the propagation of ultra-short pulses is reduced from the generalized sG equation in an appropriate scaling limit. Subsequently, the reduction to the sG equation is briefly discussed.
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