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Search Results: 1 - 10 of 21682 matches for " Min Hoan Moon "
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Successful Conservative Management of Ruptured Ovarian Cysts with Hemoperitoneum in Healthy Women
Jee Hyun Kim, Seung Mi Lee, Ji-Hyun Lee, Yu Ri Jo, Min Hoan Moon, Jonghwan Shin, Byoung Jae Kim, Kyu Ri Hwang, Taek Sang Lee, Kwang Bum Bai, Hye Won Jeon
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0091171
Abstract: Study Objective To determine the success rate of the “intended conservative management strategy” of ruptured ovarian cysts with hemoperitoneum and the risk factors for surgical interventions in healthy women of reproductive age. Methods Patients who visited the emergency department with abdominal pain and were diagnosed with a ruptured ovarian cyst with hemoperitoneum between August 2008 and June 2013 were included in this retrospective study. The diagnosis of the ruptured ovarian cysts and hemoperitoneum was based on the clinical symptoms, physical examination and ultrasound and CT imaging. The rate of surgical interventions and the risk factors for surgical intervention were determined. Results A total of 78 women were diagnosed with a ruptured ovarian cyst with hemoperitoneum. Most patients (80.8%, 63/78) were managed conservatively, and 19.2% of the patients (15/78) required a surgical intervention. In the multiple logistic regression analysis, the diastolic blood pressure (dBP) (odds ratio [OR] of 0.921 with 95% confidence interval [CI] of 0.855–0.993) and the depth of the total pelvic fluid collection in CT (DTFC_CT) (OR 1.599 with 95% CI 1.092–2.343) were the significant determining factors of surgical intervention after adjustment. The rate of surgical intervention was 6.5% vs. 15.8% vs. 77.8% in the patients with neither dBP≤70 mmHg nor DTFC_CT≥5.6 cm, those with only one of those features, and those with both, respectively. Conclusion Most cases of ruptured ovarian cysts with hemoperitoneum can be managed conservatively. A low diastolic blood pressure and a large amount of hemoperitoneum suggest the need for surgical intervention.
Basement Membrane and Cell Integrity of Self-Tissues in Maintaining Drosophila Immunological Tolerance
Moon Jong Kim,Kwang-Min Choe
PLOS Genetics , 2014, DOI: doi/10.1371/journal.pgen.1004683
Abstract: The mechanism underlying immune system recognition of different types of pathogens has been extensively studied over the past few decades; however, the mechanism by which healthy self-tissue evades an attack by its own immune system is less well-understood. Here, we established an autoimmune model of melanotic mass formation in Drosophila by genetically disrupting the basement membrane. We found that the basement membrane endows otherwise susceptible target tissues with self-tolerance that prevents autoimmunity, and further demonstrated that laminin is a key component for both structural maintenance and the self-tolerance checkpoint function of the basement membrane. Moreover, we found that cell integrity, as determined by cell-cell interaction and apicobasal polarity, functions as a second discrete checkpoint. Target tissues became vulnerable to blood cell encapsulation and subsequent melanization only after loss of both the basement membrane and cell integrity.
Targeting Cancer Cells with Reactive Oxygen and Nitrogen Species Generated by Atmospheric-Pressure Air Plasma
Hak Jun Ahn, Kang Il Kim, Nguyen Ngoc Hoan, Churl Ho Kim, Eunpyo Moon, Kyeong Sook Choi, Sang Sik Yang, Jong-Soo Lee
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0086173
Abstract: The plasma jet has been proposed as a novel therapeutic method for cancer. Anticancer activity of plasma has been reported to involve mitochondrial dysfunction. However, what constituents generated by plasma is linked to this anticancer process and its mechanism of action remain unclear. Here, we report that the therapeutic effects of air plasma result from generation of reactive oxygen/nitrogen species (ROS/RNS) including H2O2, Ox, OH?, ?O2, NOx, leading to depolarization of mitochondrial membrane potential and mitochondrial ROS accumulation. Simultaneously, ROS/RNS activate c-Jun NH2-terminal kinase (JNK) and p38 kinase. As a consequence, treatment with air plasma jets induces apoptotic death in human cervical cancer HeLa cells. Pretreatment of the cells with antioxidants, JNK and p38 inhibitors, or JNK and p38 siRNA abrogates the depolarization of mitochondrial membrane potential and impairs the air plasma-induced apoptotic cell death, suggesting that the ROS/RNS generated by plasma trigger signaling pathways involving JNK and p38 and promote mitochondrial perturbation, leading to apoptosis. Therefore, administration of air plasma may be a feasible strategy to eliminate cancer cells.
The Effect of Different Levels of Sesame Oil on Productive Performance, Egg Yolk and Blood Serum Lipid Profile in Laying Hens  [PDF]
Nguyen Duy Hoan, Mai Anh Khoa
Open Journal of Animal Sciences (OJAS) , 2016, DOI: 10.4236/ojas.2016.61011
Abstract: Addition of sesame oil into layer diets has been proved to enrich the proportion of polyunsatu-rated fatty acids in animal’s products. In this study, the effects of different levels of sesame oil in the diets on the performance, egg yolk and blood serum lipid profile of Isa Brown laying hens were investigated. A total of 96 layers were assigned into 4 groups to receive either 1 of 4 different diets contained 0.0%, 1.5%, 3.0% and 4.5% sesame oil, respectively. Sample of 12 eggs obtained from each groups were assessed for egg quality. The egg yolk fatty acid profile was determined with gas chromatography. Results revealed that the higher levels of sesame oil in the diet decreased egg production, egg weight, and egg yolk color except feed conversion ratio. In addition, supplementation of sesame oil increased the flow index of the eggs and the Haugh unite. The egg yolk lipid profile was not significantly different in the sesame oil fed groups, whereas, compare to control, it decreased the level of cholesterol. The blood serum lipid profile decreased in the sesame oil groups compare to control group. Meanwhile, monoacildigliserol also decreased in the sesame addition groups. In parallel with increasing levels of sesame oil, monounsaturated fatty acid (oleic acid) in the egg yolks significantly increased compared to the control (37.00%, 42.89%, 42.20% and 43.48%, respectively). It can be implied that sesame oil supplementation into the laying hens diet is necessary to produce monounsaturated fatty acid (MUFA) enriched eggs.
Studies of symmetries that give special quantum states the "right to exist"
Hoan Bui Dang
Physics , 2015,
Abstract: In this thesis we study symmetric structures in Hilbert spaces known as symmetric informationally complete positive operator-valued measures (SIC-POVMs), mutually unbiased bases (MUBs), and MUB-balanced states. Our tools include symmetries such as the Weyl-Heisenberg (WH) group symmetry, Clifford unitaries, Zauner symmetry, and Galois-unitaries (g-unitaries), which are non-linear operators defined to generalize the notion of anti-unitaries.
Automated Change Detection and Reactive Clustering in Multivariate Streaming Data
Dang-Hoan Tran
Computer Science , 2013,
Abstract: Many automated systems need the capability of automatic change detection without the given detection threshold. This paper presents an automated change detection algorithm in streaming multivariate data. Two overlapping windows are used to quantify the changes. While a window is used as the reference window from which the clustering is created, the other called the current window captures the newly incoming data points. A newly incoming data point can be considered a change point if it is not a member of any cluster. As our clustering-based change detector does not require detection threshold, it is an automated detector. Based on this change detector, we propose a reactive clustering algorithm for streaming data. Our empirical results show that, our clustering-based change detector works well with multivariate streaming data. The detection accuracy depends on the number of clusters in the reference window, the window width.
Communication-Efficient and Exact Clustering Distributed Streaming Data
Dang-Hoan Tran
Computer Science , 2012,
Abstract: A widely used approach to clustering a single data stream is the two-phased approach in which the online phase creates and maintains micro-clusters while the off-line phase generates the macro-clustering from the micro-clusters. We use this approach to propose a distributed framework for clustering streaming data. Our proposed framework consists of fundamen- tal processes: one coordinator-site process and many remote-site processes. Remote-site processes can directly communicate with the coordinator-process but cannot communicate the other remote site processes. Every remote-site process generates and maintains micro- clusters that represent cluster information summary, from its local data stream. Remote sites send the local micro-clusterings to the coordinator by the serialization technique, or the coordinator invokes the remote methods in order to get the local micro-clusterings from the remote sites. After the coordinator receives all the local micro-clusterings from the remote sites, it generates the global clustering by the macro-clustering method. Our theoretical and empirical results show that, the global clustering generated by our distributed framework is similar to the clustering generated by the underlying centralized algorithm on the same data set. By using the local micro-clustering approach, our framework achieves high scalability, and communication-efficiency.
1,4-Diazabicyclo[2.2.2]octane–trans,trans-hexa-2,4-dienedioic acid (1/1)
Suk-Hee Moon,Ki-Min Park
Acta Crystallographica Section E , 2012, DOI: 10.1107/s160053681202942x
Abstract: The title 1:1 co-crystal, C6H12N2·C6H6O4, the dicarboxylic acid molecule is close to planar [r.m.s. deviation from the mean plane = 0.07 (1) ]. In the crystal, the two molecules are arranged alternately and are linked by O—H...N hydrogen bonds, leading to the formation of a chain along the [20-1] direction. The chains are assembled into a two-dimensional framework parallel to the (102) plane through weak C—H...O hydrogen bonds between the two types of molecules.
4,4′-Bipyridine–trans,trans-hexa-2,4-dienedioic acid (1/1)
Suk-Hee Moon,Ki-Min Park
Acta Crystallographica Section E , 2012, DOI: 10.1107/s1600536812012391
Abstract: The title cocrystal, C10H8N2·C6H6O4, crystallizes with half-molecules of 4,4′-bipyridine and trans,trans-hexa-2,4-dienedioic acid in the asymmetric unit, as each is located about a crystallographic inversion center. The bipyridine molecule is planar from symmetry. In the dicarboxylic acid molecule, the O—C—C—C torsion angle is 13.0 (2)°. In the crystal, O—H...N and C—H...O hydrogen bonds generate a three-dimensional network.
1,4-Bis(4-pyridylsulfanylmethyl)benzene
Suk-Hee Moon,Ki-Min Park
Acta Crystallographica Section E , 2008, DOI: 10.1107/s1600536808017571
Abstract: In the title compound, C18H16N2S2, a crystallographic inversion centre lies at the centre of the benzene ring, and the two terminal 4-mercaptopyridyl groups adopt an anti geometry. Each benzene ring makes a dihedral angle of 55.4 (1)° with the plane of the benzene fragment. The crystal structure is stabilized by C—H...π interactions between a benzene H atom and a pyridyl ring of a neighbouring molecule. In addition, the crystal structure exhibits intermolecular C—H...N interactions.
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