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Search Results: 1 - 10 of 11094 matches for " Midori Hentona;Belfort Jr "
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Qualidade de vida e custos diretos em pacientes com blefaroespasmo essencial e espasmo hemifacial, tratados com toxina botulínica-A
Osaki, Midori Hentona;Belfort Jr, Rubens;
Arquivos Brasileiros de Oftalmologia , 2004, DOI: 10.1590/S0004-27492004000100008
Abstract: purpose: to evaluate both the costs and the impact on the quality of life of essential blepharospasm and hemifacial spasm patients treated with botulinum toxin-a. methods: 28 patients (16 essential blepharospasm and 12 hemifacial spasm), treated with btx-a, were evaluated by means of two research tools, namely medical outcomes study short form healthy survey, and fahn disability rating scale. the costs were mainly calculated on the basis of the toxin units used by each patient during a one-year period. results: the total estimated direct cost was estimated at 1,081.62 reais per year (±89.39) for essential blepharospasm and 618.06 reais per year (±60.06) for hemifacial spasm, at an outpatient level (p<0.001). before treatment all domains of sf-36 were significantly worse in both diseases. under effective treatment with botulinum toxin-a the increases in the indices of sf-36 show changes in the general health rates of the population under study, with a statistically significant difference between the pre and post answers (p<0.05). in relating sf-36 with the fahn disability rating scale, the essential blepharospasm cases showed significant positive relationships (functional capacity, general health, emotional aspect and social aspects) while in the hemifacial spasm patients no correlation was found. conclusion: the present study demonstrates a remarkable negative impact of both diseases on the quality of life of essential blepharospasm and hemifacial spasm patients, as well as a significant improvement of both diseases after botulinum toxin-a treatment. furthermore, the research data seem to justify the high costs of botulinum toxin-a treatment in view of its considerable benefits regarding the patients' quality of life.
Qualidade de vida e custos diretos em pacientes com blefaroespasmo essencial e espasmo hemifacial, tratados com toxina botulínica-A
Osaki Midori Hentona,Belfort Jr Rubens
Arquivos Brasileiros de Oftalmologia , 2004,
Abstract: OBJETIVO: Avaliar os custos e a qualidade de vida dos pacientes com blefaroespasmo essencial e espasmo hemifacial, submetidos à terapia com a toxina botulínica-A. MéTODOS: Vinte e oito pacientes, sendo 16 com blefaroespasmo essencial e 12 com espasmo hemifacial, tratados com toxina botulínica-A, foram avaliados por meio de dois instrumentos: o SF-36 e a Escala de Disfun o de Blefaroespasmo. Os custos foram calculados segundo o número de unidades da toxina utilizadas por cada paciente no período de um ano. RESULTADOS: O custo total direto foi estimado em 1081,62 reais por ano (±89,39) para blefaroespasmo essencial e 618,06 reais por ano (±60,06) para espasmo hemifacial, para tratamento ambulatorial (p<0,001). Antes do tratamento, todos os domínios do SF-36 foram significantemente piores em ambas as doen as. Sob tratamento efetivo com toxina botulínica-A, os aumentos nos índices do SF-36 evidenciaram mudan as nas taxas de saúde geral da popula o em estudo, com diferen a estatisticamente significante entre as respostas pré e pós-tratamento (p<0,05). Relacionando-se o SF-36 com Escala de Disfun o de Blefaroespasmo, foram observadas nos casos de blefaroespasmo essencial, rela es significantes positivas (capacidade funcional, estado geral, aspecto emocional e aspectos sociais), ao passo que nos pacientes com espasmo hemifacial n o foi encontrada nenhuma correla o. CONCLUS O: Este estudo demonstra notável impacto negativo das doen as na qualidade de vida desses pacientes, e uma significante melhora em ambas as doen as após tratamento com toxina botulínica-A. Além disso, os dados fornecem subsídios para justificar o alto custo da aquisi o da toxina botulínica-A, devido a seus consideráveis benefícios para a qualidade de vida.
Temporary management of involutional entropion with octyl-2-cyanoacrylate liquid bandage application
Osaki, Teissy;Osaki, Midori Hentona;Osaki, Tammy Hentona;
Arquivos Brasileiros de Oftalmologia , 2010, DOI: 10.1590/S0004-27492010000200004
Abstract: purpose: to evaluate the use of octyl-2-cyanoacrylate liquid bandage (band-aid liquid?, ethicon, johnson & johnson, new jersey, usa) as a temporary treatment in patients awaiting surgical repair for involutional entropion. methods: thirteen patients (15 eyelids) with involutional entropion were evaluated while they waited for surgical intervention. the lids were repositioned by the application of octyl-2-cyanoacrylate liquid bandage in the malar fold. patients were followed-up at days 1, 7 and 15. assessment and duration of correction were recorded. results: all the patients presented successful correction at day 1, with significant improvements in signs and symptoms. the mean duration of action of the octyl2-cyanoacrylate liquid bandage was three days. no ocular or dermatological reactions were noted. conclusion: octyl-2-cyanoacrylate liquid bandage showed to be a simple, safe and effective option to temporarily treat involutional entropion, while patients waited for surgical intervention.
Avalia??o de qualidade de vida em portadores de blefaroptose
Asano, Márcia Emiko;Osaki, Midori Hentona;
Arquivos Brasileiros de Oftalmologia , 2006, DOI: 10.1590/S0004-27492006000400016
Abstract: purpose: to assess the health-related quality of life in blepharoptosis patients and the impact after surgical management on their quality of life. methods: twenty-one patients with congenital or acquired blepharoptosis completed a questionnaire which was adapted from the visual function questionnaire (vfq), before and after surgical management. results: mean preoperative score was 74 and mean postoperative score was 81 and there was a statistically significant difference between mean pre- and postoperative scores of 7 (p=0.004). there was a statistically significant difference only for the mental health subdomain (p=0.001) in the evaluation of the questions (a=0.002) and subdomains (a=0.004). conclusion: the quality of life in blepharoptosis patients was significantly better after surgical management in the assessment using the vfq. the outcomes emphasize the need for of using questionnaires designed specifically for this disease.
Uso de ganciclovir 0,15% gel para tratamento de ceratoconjuntivite adenoviral
Yabiku, Simone Tiemi;Yabiku, Mariann Midori;Bottós, Kátia Mantovani;Araújo, Aline Lutz;Freitas, Denise de;Belfort Jr., Rubens;
Arquivos Brasileiros de Oftalmologia , 2011, DOI: 10.1590/S0004-27492011000600007
Abstract: purpose: to evaluate the efficacy and the toxicity of 0.15% ganciclovir gel in the treatment of adenoviral conjunctivitis and in preventing ocular complications after adenoviral conjunctivitis, such as corneal infiltrates and pseudomembranes. methods: double blind, interventional and randomized clinical trial. thirty-three patients with clinical diagnosis of adenoviral conjunctivitis with onset of symptoms for five or less days were randomized in two groups: group 1 (treatment) with 19 patients used ganciclovir gel and group 2 (control) with 14 patients used artificial tears without preservative. patients answered a questionnaire of signs and symptoms and were submitted to an ophthalmologic exam. on the 6th and 10th days of treatment they answered the same questions and were re-examined by the same ophthalmologist. signs and symptoms were compared. t student, mann-whitney e wilcoxon tests were used to statistical analysis. results: trend of better response in the treatment group in relation of patients' perception, besides faster improvement of this group compared to the control group (p=0.26). there were lower transmission to the fellow eye (p=0.86) and to people living together (p=0.16) in the treatment group. no statistical difference related to signs and symptoms of conjunctivitis were found comparing both groups. we observed statistical difference in pain, itch and photophobia only in the treatment group, comparing each group alone. no toxicity and more tolerance of the ganciclovir were observed. there was no statistical difference in the ocular complications after conjunctivitis between both groups. conclusions: this study showed trend of better and faster response of the signs and symptoms of the patients treated with ganciclovir compared with the control group, but with no statistical significant. these results need to be confirmed by additional studies, with more patients and longer follow-up. clinical trails.gov: nct01349452
Resultados clínicos e satisfa??o dos pacientes após blefaroplastia inferior
Viana, Giovanni André Pires;Osaki, Midori Hentona;Nishi, Mauro;
Revista do Colégio Brasileiro de Cirurgi?es , 2011, DOI: 10.1590/S0100-69912011000500006
Abstract: objective: to evaluate the results of fifty patients undergoing transcutaneous lower eyelid blepharoplasty. methods: we conducted a prospective, randomised, controlled trial between april 2005 and may 2007. patients were randomly divided into two groups: group 1 consisted of 25 surgical patients undergoing traditional lower blepharoplasty and routine lateral canthopexy; group 2 consisted of 25 patients undergoing lower blepharoplasty with fat bags transposition and routine lateral canthopexy. we used the rosenberg self-esteem scale unifesp / epm to assess patients' self-esteem. we also requested the participation of three independent surgeons, who examined the pre and postoperative photographs and quantified the results with the aid of a topographic scale. results: the mean age was 48.8 years, predominantly females (96%). the analysis of photographs showed a 96% significant improvement. self-esteem scores improved from a preoperative average of 5.1 (sd = 4.1) to a mean of 3.6 (sd = 3.5) six months after the operation (p = 0.001). conclusion: both procedures are safe and effective with low complication rates, causing improvement of self-esteem assessed six months after the operation.
Abstract
Belfort Jr Rubens
Arquivos Brasileiros de Oftalmologia , 2002,
Abstract:
Treatment of cytomegalovirus retinitis with an intraocular sustained-release ganciclovir implant
Muccioli, C.;Belfort Jr., R.;
Brazilian Journal of Medical and Biological Research , 2000, DOI: 10.1590/S0100-879X2000000700008
Abstract: the objective of this prospective study was to evaluate the efficacy and complications of the use of an intraocular sustained-release ganciclovir implant for the treatment of active cytomegalovirus (cmv) retinitis in aids patients. thirty-nine eyes of 26 patients were submitted to ocular surgery. all patients underwent complete ocular examination before and after surgery. the surgical procedure was always done under local anesthesia using the same technique. the mean time for the surgical procedure was 20 min (range, 15 to 30 min). the average follow-up period was 3.7 months. of all patient, only 4 presented recurrence of retinitis after 8, 8, 9 and 2 months, respectively. three of them received a successful second implant. all 39 eyes of the 26 patients presented healing of retinitis as shown by clinical improvement evaluated by indirect binocular ophthalmoscopy and retinography. retinitis healed within a period of 4 to 6 weeks in all patients, with clinical regression signs from the third week on. six (15.4%) eyes developed retinal detachment. none of the patients developed cmv retinitis in the contralateral eye. the intraocular implant proved to be effective in controlling the progression of retinitis for a period of up to 8 months even in patients for whom systemic therapy with either ganciclovir or foscarnet or both had failed. the intraocular sustained-release ganciclovir implant proved to be a safe new procedure for the treatment of cmv retinitis, avoiding the systemic side effects caused by the intravenous medications and improving the quality of life of the patients.
Treatment of cytomegalovirus retinitis with an intraocular sustained-release ganciclovir implant
Muccioli C.,Belfort Jr. R.
Brazilian Journal of Medical and Biological Research , 2000,
Abstract: The objective of this prospective study was to evaluate the efficacy and complications of the use of an intraocular sustained-release ganciclovir implant for the treatment of active cytomegalovirus (CMV) retinitis in AIDS patients. Thirty-nine eyes of 26 patients were submitted to ocular surgery. All patients underwent complete ocular examination before and after surgery. The surgical procedure was always done under local anesthesia using the same technique. The mean time for the surgical procedure was 20 min (range, 15 to 30 min). The average follow-up period was 3.7 months. Of all patient, only 4 presented recurrence of retinitis after 8, 8, 9 and 2 months, respectively. Three of them received a successful second implant. All 39 eyes of the 26 patients presented healing of retinitis as shown by clinical improvement evaluated by indirect binocular ophthalmoscopy and retinography. Retinitis healed within a period of 4 to 6 weeks in all patients, with clinical regression signs from the third week on. Six (15.4%) eyes developed retinal detachment. None of the patients developed CMV retinitis in the contralateral eye. The intraocular implant proved to be effective in controlling the progression of retinitis for a period of up to 8 months even in patients for whom systemic therapy with either ganciclovir or foscarnet or both had failed. The intraocular sustained-release ganciclovir implant proved to be a safe new procedure for the treatment of CMV retinitis, avoiding the systemic side effects caused by the intravenous medications and improving the quality of life of the patients.
Influência da toxina botulínica tipo A na fun??o lacrimal de pacientes com distonias faciais
Oliveira, Fernanda Castro de;Oliveira, Gustavo Castro de;Cariello, Angelino Julio;Felberg, Sergio;Osaki, Midori Hentona;
Arquivos Brasileiros de Oftalmologia , 2010, DOI: 10.1590/S0004-27492010000500003
Abstract: purpose: to analyze the influence of botulinum toxin on the lacrimal function of patients with facial dystonias. methods: patients with the diagnosis of hemifacial spasm or benign essential blepharospasm were evaluated and invited to answer the ocular surface index disease (osid) questionnaire. all patients underwent schirmer i and basal tests; break-up time (but) test and lacrimal clearance evaluation. on the following day, the patients were treated with botulinum toxin. the ocular surface index disease questionnaire and all the initial tests were reapplied 30 days after the treatment by the same examiner. results: twenty-six patients were enrolled in this study, 15 (57.7%) with hemifacial spasm and 11 (42.3%) with benign essential blepharospasm. the mean age of patients with hemifacial spasm was 70.9 ± 13.3 years and the male:female ratio was 1:1.5. in the group of patients with benign essential blepharospasm, the mean age was 68.9 ± 8.4 years with a female preponderance (90.0%). after the treatment, the ocular surface index disease score, schirmer i and basal tests score decreased in both groups. the mean of break-up time test increased significantly in both groups. the lacrimal clearance evaluation showed a greater number of eyes that achieved a complete drainage of the tears after the treatment in both groups. conclusion: the treatment with botulinum toxin improved dry eye symptoms in patients with facial dystonia. despite of the aqueous portion of tear have decreased, blink modifications improved the tear stability and drainage.
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