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Search Results: 1 - 10 of 12288 matches for " Michaela Bitarello do;Formigoni "
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Implanta??o de rotinas de rastreamento do uso de risco de álcool e de uma interven??o breve na aten??o primária à saúde: dificuldades a serem superadas
Ronzani, Telmo Mota;Ribeiro, Mário Sérgio;Amaral, Michaela Bitarello do;Formigoni, Maria Lúcia Oliveira de Souza;
Cadernos de Saúde Pública , 2005, DOI: 10.1590/S0102-311X2005000300019
Abstract: the variety of problems related to the so-called hazardous patterns of alcohol use make the latter a prominent public health concern. screening instruments associated with brief interventions in primary care provide one of the frequently recommended secondary prevention strategies. the objective of this study was to assess the implementation of this strategy as a routine practice in primary health care services in the city of juiz de fora, minas gerais state, brazil. a qualitative design was employed, including the application of semi-structured interviews for managers and health care professionals in the city's public health system, in addition to content analysis and participant observation. results point to difficulties in the effective implementation of such routines both by managers and health care professionals. health care professionals limit the approach to alcohol-dependent patients and demonstrate lack of motivation for preventive work. health services managers experience difficulties in the organization and administration of such instruments, despite affirming their interest in the project.
Implanta o de rotinas de rastreamento do uso de risco de álcool e de uma interven o breve na aten o primária à saúde: dificuldades a serem superadas
Ronzani Telmo Mota,Ribeiro Mário Sérgio,Amaral Michaela Bitarello do,Formigoni Maria Lúcia Oliveira de Souza
Cadernos de Saúde Pública , 2005,
Abstract: Tendo em vista os diversos problemas associados ao assim chamado uso de risco de álcool, ele é considerado uma relevante quest o de saúde pública. Uma das estratégias de preven o secundária recomendadas é a utiliza o de instrumentos de rastreamento associados a interven es breves em servi os de aten o primária à saúde. O objetivo deste estudo foi avaliar o processo de implanta o desta estratégia na rotina de aten o primária à saúde da cidade de Juiz de Fora, Minas Gerais, Brasil. Foi utilizada uma abordagem qualitativa, incluindo a aplica o de entrevistas semi-estruturadas a gestores e/ou profissionais da assistência do Sistema Municipal de Saúde, associadas à análise de conteúdo e observa o participante. Os resultados indicam que há dificuldades para a implanta o efetiva destas rotinas, tanto em rela o aos gestores quanto aos profissionais envolvidos diretamente na sua execu o. Quanto aos profissionais destacam-se a restri o da abordagem a dependentes de álcool e a falta de motiva o dos profissionais para trabalhos preventivos. Quanto aos gestores, foram detectadas dificuldades práticas no processo de organiza o e gerenciamento, a despeito de um afirmado interesse no projeto.
Is there a feeding strategy to increase milk casein content?
A. Formigoni,G. Biagi
Italian Journal of Animal Science , 2010, DOI: 10.4081/ijas.2007.1s.231
Abstract: Because more than 60% of milk produced in Italy is transformed into cheese, milk economical value strongly depends on cheese yield. Among the factors that influence cheese yield, milk casein and fat content plays a major role: when milk is converted into Grana Padano and Parmigiano reggiano, three grams of seasoned cheese are produced from one gram of milk casein.....
Adsorption Organic Cationic Dyes of Oxycelluloses and Linters  [PDF]
Michaela Filipi, Miloslav Milichovsky
Journal of Encapsulation and Adsorption Sciences (JEAS) , 2014, DOI: 10.4236/jeas.2014.41001
Abstract: Natural cellulose and oxycellulose are heterogeneous highly hydrated substances. They have the same chemical composition, but different size of molecules and representation of COOH groups organized into complex supramolecular structure. The oxycellulosic adsorption capacity of organic cationic dyes increases with increasing -COOH group content and distinctly increases with other competitive ions in the aqueous solution.
Separation of Fe(II) by the DEMI and TEMPO Oxidized Cellulose  [PDF]
Michaela Filipi, Miloslav Milichovsky
Journal of Encapsulation and Adsorption Sciences (JEAS) , 2015, DOI: 10.4236/jeas.2015.53008
Abstract: The description of some adsorption properties and behaviour of oxycellulose with Fe2+ ions is presented. Filter media from oxycelluloses materials have enormous sorption activity. There is described a sorption mechanism of poly 1,4-β-D anhydroglucuronic acid (PAGA). Utilisation of UV-VIS spectroscopy is shown on the adsorption process of optimalisation of oxycelluloses application. Supporting influence is demonstrated on the adsorption isotherms of Fe2+ ions in the competitive environment of NaCl, MgCl2.
Keeping innate immunity at bay
Michaela Torkar
Genome Biology , 2002, DOI: 10.1186/gb-spotlight-20020731-01
Abstract: Kobayashi et al. show that lack of IRAK-M causes increased production of inflammatory cytokines, including interleukin-6 and tumor-necrosis factor α, and an enhanced inflammatory response in the gut of IRAK-M-/- mice infected with the Gram-negative pathogen Salmonella typhimurium. IRAK-M-/- macrophages did not develop endotoxin tolerance to the bacterial lipopolysaccharide, a little-understood regulatory mechanism that protects from endotoxic shock. TLR signaling following stimulation of macrophages was enhanced in the absence of IRAK-M, and immunoprecipitations suggested that, in wild-type mice, IRAK-M inhibits the release of activating IRAK kinases from the TLR signaling complex, thereby blocking downstream signaling events.Kobayashi et al. conclude that the negative regulatory function of IRAK-M may be required for preventing endotoxic shock and immunopathologies such as Crohn's and other inflammatory bowel diseases.
Molecular evolution of language
Michaela Torkar
Genome Biology , 2002, DOI: 10.1186/gb-spotlight-20020815-01
Abstract: P??bo and colleagues show that human FOXP2 differs in the coding of two amino acids from chimpanzee, gorilla, orang-utan, rhesus monkey and from mouse. A third amino-acid difference is found between human and mouse, but not between human and other apes. Exon 7, which encodes the two amino acids, is highly conserved among humans, and no amino-acid polymorphism was found in 44 human chromosomes from all major continents. Analysis of allele frequencies in humans and apes indicated that the two amino-acid replacements specific to humans are the best candidates for selected sites. This FOXP2 variant was probably fixed in the human population during the past 200,000 years and may have enabled humans to control orofacial movements and therefore the development of speech.
DNA sequences associated with chromatin proteins
Michaela Torkar
Genome Biology , 2000, DOI: 10.1186/gb-2000-1-2-reports0051
Abstract: Escherichia coli DNA adenine methyltransferase (Dam), which catalyzes methylation of adenine, was used as a reporter enzyme fused to Drosophila HP1. The fusion construct was transfected into Drosophila cell lines or used to generate transgenic fly lines. HP1 became integrated into the chromatin structure and directed the Dam methyltransferase to HP1-associated DNA sequences. These sequences were subsequently marked by adenine methylation. Because methylation of adenine does not normally occur in eukaryotes, sites of Dam methylation could be mapped using methylation-specific antibodies or restriction enzymes. The authors show that HP1 guided the Dam enzyme to heterochromatic loci in vivo. Previously unidentified potential HP1 targets included the histone gene-cluster repeat, which is thought to have heterochromatic features although located in euchromatin, as well as the rDNA repeat. The new technique may allow genome-wide mapping of DNA sequences targeted by chromatin-associated factors in various eukaryotes.The new technique, called DamID (for Dam identification), was first tested using the yeast regulator protein Gal4 as the fusion partner. The complex was successfully targeted to inserted Gal4-binding sites in the genome of a transgenic Drosophila line. Although Dam has an intrinsic DNA-binding activity (resulting in some 'background' adenine methylation in the absence of the fused chromatin protein), targeting of the enzyme led to a tenfold increase of methylation in the vicinity of DNA-binding sites of the Dam fusion partner. This enrichment was sufficient for positive identification of target sequences. The technique was applied to cell-culture systems and the whole organism, which was possible because expression of the bacterial enzyme does not seem to affect Drosophila development. A PCR-based assay allowed sensitive quantification of protein-DNA interactions.The paper is accompanied by a News and Views article accessible to subscribers through the Nature Bi
Investigación y Desarrollo , 2008,
Abstract: since the late 1970s the austrian capital vienna is one of the most exciting european examples for successful and well-balanced urban renewal policy. the strategies to safeguard historical building fabric are mainly influenced by a welfare state urban development policy. during the last three decades urban renewal activities, mainly funded and/or supported by public aid and distributed all over the urban space, kept the urban development in balance and avoided occurring social segregation as well as the growth of slums. in the meantime, neo-liberalistic globalization as well as the chance to get financial support for large-scale urban projects form the european union generate some renunciation from this successful strategy. as the viennese municipality more and more turns towards prestigious projects to enhance international location competitiveness, the cycle of urban decay in the former renewed quarters might start again.
Negative impacts of high-stakes testing
Michaela Minarechová
Journal of Pedagogy / Pedagogicky casopis , 2012, DOI: 10.2478/v10159-012-0004-x
Abstract: High-stakes testing is not a new phenomenon in education. It has become part of the education system in many countries. These tests affect the school systems, teachers, students, politicians and parents, whether that is in a positive or negative sense. High-stakes testing is associated with concepts such as a school's accountability, funding and parental choice of school. The study aims to explain high-stakes testing, how it is created and developed in selected countries and look at the negative impacts of tests on various actors within this relationship.
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