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Search Results: 1 - 10 of 186053 matches for " Michael B. Cortie "
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The weird world of nanoscale gold
Michael B. Cortie
Gold Bulletin , 2004, DOI: 10.1007/BF03215512
Abstract: Protagonists in the emerging field of nanotechnology have as their objective the design, construction and study of useful devices based on nanoscale materials and objects. Objects or structures that have at least one important dimension in the range 0.5 to perhaps 50 nm may be considered to be in the nanoscale domain. These sizes lie far below the 200 nm or so that can be resolved with an optical microscope, and are closer in size to the 0.3 nm diameter of individual atoms. The field of nanotechnology is attracting keen interest at present. The excitement is motivated by the observation that control of matter at the nanoscale holds the promise of, amongst others, faster computing, better medicines, and more useful materials. In this paper, the physical phenomena on which this optimism is based are broadly discussed and explained. Where appropriate, examples of the rather different and curious properties of gold at the nanoscale are used to illustrate the points covered.
The development of Spangold
Ira M. Wolff,Michael B. Cortie
Gold Bulletin , 1994, DOI: 10.1007/BF03214729
Abstract: The underlying mechanisms of martensitic phase transformations in gold alloys have attracted a great deal of study. Whereas their technological exploitation in shape-memory devices has found only limited application, theSpangold concept introduces a novel application — that of using the transformation to decorate gold ornaments. This article examines the attributes of suitable alloys and the development of a prototype alloy for use in jewellery.
Tunable infrared absorption by metal nanoparticles: The case for gold rods and shells
Nadine Harris,Michael J Ford,Paul Mulvaney,Michael B Cortie
Gold Bulletin , 2008, DOI: 10.1007/BF03215618
Abstract: Nanoparticles of elements such as Au, Al or Ag have optical extinction cross-sections that considerably surpass their geometric cross-sections at certain wavelengths of light. While the absorption and scattering maxima for nanospheres of these elements are relatively insensitive to particle diameter, the surface plasmon resonance of Au nanoshells and nanorods can be readily tuned from the visible into the infrared by changing the shape of the particle. Here we compare nanoshells and nanorods in terms of their ease of synthesis, their optical properties, and their longer term technological prospects as tunable “plasmonic absorbers”. While both particle types are now routinely prepared by wet chemistry, we submit that it is more convenient to prepare rods. Furthermore, the plasmon resonance and peak absorption efficiency in nanorods may be readily tuned into the infrared by an increase of their aspect ratio, whereas in nanoshells such tuning may require a decrease in shell thickness to problematic dimensions.
Preparation of nanoscale gold structures by nanolithography
Nicholas Stokes,Andrew M McDonagh,Michael B Cortie
Gold Bulletin , 2007, DOI: 10.1007/BF03215605
Abstract: Gold is the material of first choice for the realisation of a large number of interesting nanoscale devices and structures due to its unique chemical and optical properties. However, conventional photolithographic processes cannot be used to manufacture such tiny structures in gold (or any other material) due to limitations imposed by the diffraction of light. New methods of lithography have been developed to overcome this limitation. In this article we review these new nanolithographic techniques, describe how they have been used to produce nanoscale precious metal artefacts, and briefly survey some of the existing and potential applications for these structures.
Guest Editorial
Michael Cortie
Gold Bulletin , 2003, DOI: 10.1007/BF03215493
Rainbow’s End: Gold-themed papers at the 2008 International Conference on Nanoscience and Nanotechnology
Michael Cortie
Gold Bulletin , 2008, DOI: 10.1007/BF03216601
Michael Cortie
Gold Bulletin , 2006, DOI: 10.1007/BF03215534
In Vivo Study of Spherical Gold Nanoparticles: Inflammatory Effects and Distribution in Mice
Hui Chen, Alisha Dorrigan, Sonia Saad, Dominic J. Hare, Michael B. Cortie, Stella M. Valenzuela
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0058208
Abstract: Objectives Gold nanoparticles (AuNPs) of 21 nm have been previously well characterized in vitro for their capacity to target macrophages via active uptake. However, the short-term impact of such AuNPs on physiological systems, in particular resident macrophages located in fat tissue in vivo, is largely unknown. This project investigated the distribution, organ toxicity and changes in inflammatory cytokines within the adipose tissue after mice were exposed to AuNPs. Methods Male C57BL/6 mice were injected intraperitoneally (IP) with a single dose of AuNPs (7.85 μg AuNPs/g). Body weight and energy intake were recorded daily. Tissues were collected at 1 h, 24 h and 72 h post-injection to test for organ toxicity. AuNP distribution was examined using electron microscopy. Proinflammatory cytokine expression and macrophage number within the abdominal fat pad were determined using real-time PCR. Results At 72 hours post AuNP injection, daily energy intake and body weight were found to be similar between Control and AuNP treated mice. However, fat mass was significantly smaller in AuNP-treated mice. Following IP injection, AuNPs rapidly accumulated within the abdominal fat tissue and some were seen in the liver. A reduction in TNFα and IL-6 mRNA levels in the fat were observed from 1 h to 72 h post AuNP injection, with no observable changes in macrophage number. There was no detectable toxicity to vital organs (liver and kidney). Conclusion Our 21 nm spherical AuNPs caused no measurable organ or cell toxicity in mice, but were correlated with significant fat loss and inhibition of inflammatory effects. With the growing incidence of obesity and obesity-related diseases, our findings offer a new avenue for the potential development of gold nanoparticles as a therapeutic agent in the treatment of such disorders.
“Nanoporous gold”, A. Wittstock et al. (eds.)
M. B. Cortie
Gold Bulletin , 2012, DOI: 10.1007/s13404-012-0072-7
Conference Report: Nano Tech + Future 2003 Chiba, Japan, February ’03
M. B. Cortie
Gold Bulletin , 2003, DOI: 10.1007/BF03214870
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