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Search Results: 1 - 10 of 20737 matches for " Miao Zhong "
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Endovascular therapy of ischemic cerebrovascular disease
MIAO Zhong-rong,MA Ning
Chinese Journal of Contemporary Neurology and Neurosurgery , 2013, DOI: 10.3969/j.issn.1672-6731.2013.03.003
Nanotechnologies for Curcumin: An Ancient Puzzler Meets Modern Solutions
Shengpeng Wang,Miao Tan,Zhangfeng Zhong,Meiwan Chen,Yitao Wang
Journal of Nanomaterials , 2011, DOI: 10.1155/2011/723178
Abstract: Curcumin, a low-molecular-weight natural polyphenol mainly found in the plant Curcuma longa (turmeric), is widely used as a food colorant and as a potential protective agent against several chronic diseases including cancer, HIV-infection, neurological, cardiovascular, and skin diseases. Moreover, evidences from long-term use process and preclinical trials have demonstrated low toxicity of curcumin, even at relatively high doses. However, it has been well known that the application of curcumin was limited owing to its water insolubility, instability, and poor bioavailability. For decades, many attempts have been made to compensate for these disadvantages, with the development of improved delivery platforms as the feasible approaches. The past ten years witnessed the encouraging progress in the use of nanoscale drug delivery systems on curcumin such as loading curcumin into liposomes or nanoparticles, forming self-microemulsifying drug delivery systems (SMEDDS), cyclodextrin inclusions, and solid dispersions, as well as the latest reported technologies such as nadodisks and nanotubes. This paper summarizes the recent works on the design and development of nanoscale delivery systems of curcumin, with the goal of harnessing the true difficulties of this multifunctional agent in the clinical arena. 1. Introduction Curcumin (Figure 1), an active constituent mainly derived from Curcuma longa (turmeric), is a natural yellow-orange polyphenol which has been used for its medicinal benefits for centuries [1, 2]. Curcumin was firstly extracted in impure form in 1815, then in 1870 the pure crystalline state was prepared. Almost three decades later, its composition was finally elucidated as 1, 6-heptadiene-3, 5-dione-1, 7-bis-(4-hydroxy-3-methoxyphenyl)-(1E, 6E) [3–6]. In China, curcumin has been used as a part of herbal medicine for centuries to alleviate throbbing pain in the chest and hypochondriac region, mass in abdomen, and pain of the shoulder due to win-cold or traumatic injuries. The accumulating of experimental and clinical evidences indicates that curcumin has a variety of pharmacological activities, such as antitumor, antiinflammatory, antivirus, antioxidation, anti-HIV, and low toxicity [7–11]. Figure 1: Chemical structure of curcumin. However, good things never come easy. Applicational advancement of curcumin has been hindered by its water insolubility, degradation at alkaline pH, and photodegradation and thus extremely low bioavailability in both vascular and oral administration [12, 13]. Therefore, many approaches have been investigated, including
In Situ Biodiesel Production from Fast-Growing and High Oil Content Chlorella pyrenoidosa in Rice Straw Hydrolysate
Penglin Li,Xiaoling Miao,Rongxiu Li,Jianjiang Zhong
Journal of Biomedicine and Biotechnology , 2011, DOI: 10.1155/2011/141207
Abstract: Rice straw hydrolysate was used as lignocellulose-based carbon source for Chlorella pyrenoidosa cultivation and the feasibility of in situ biodiesel production was investigated. 13.7 g/L sugar was obtained by enzymatic hydrolyzation of rice straw. Chlorella pyrenoidosa showed a rapid growth in the rice straw hydrolysate medium, the maximum biomass concentration of 2.83 g/L was obtained in only 48 hours. The lipid content of the cells reached as high as 56.3%. In situ transesterification was performed for biodiesel production. The optimized condition was 1 g algal powder, 6 mL n-hexane, and 4 mL methanol with 0.5 M sulfuric acid at the temperature of 90°C in 2-hour reaction time, under which over 99% methyl ester content and about 95% biodiesel yield were obtained. The results suggested that the method has great potential in the production of biofuels with lignocellulose as an alternative carbon source for microalgae cultivation.

MIAO Zhong-Lin,

红外与毫米波学报 , 2001,
Abstract: GaAs/AlGaAs asymmetrical coupling double quantum wells (ACDQW) were grown with MBE with the combinative implantation method, and several areas of coupling quantum well with different implantation ion of As + and H + and different ion doses in single wafer were obtained. Without rapid thermal annealing procedure, maximum difference of transition energy of intersubbands of 100meV was found from the photoluminescence spectra measured at room temperature. During the implantation process, the energy shift caused by combinative implanation was found to be larger than that caused by ion implantation individually.
Situs inversus totalis with carcinoma of gastric cardia: a case report
Ke Pan,Dewu Zhong,Xiongying Miao,Guoqing Liu
World Journal of Surgical Oncology , 2012, DOI: 10.1186/1477-7819-10-263
Abstract: Situs inversus is an uncommon anomaly with rare incidence. Some cases of situs inversus totalis have been described with different types of associations. Here we report a case of situs inversus with carcinoma of the gastric cardia.
Related complications of angioplasty and stenting in the treatment for intracranial atherosclerotic stenosis
LI Xin,MA Ning,LIU Lian,MIAO Zhong-rong
Chinese Journal of Contemporary Neurology and Neurosurgery , 2013, DOI: 10.3969/j.issn.1672-6731.2013.03.005
Abstract: Intracranial atherosclerotic stenosis causes acute ischemic stroke in a significant number of patients. Nowadays, the percutaneous transluminal angioplasty and stenting (PTAS) is a major method for the treatment of intracranial atherosclerotic stenosis, which can be used in patients with acute or subacute ischemic stroke, especially in patients with severe intracranial arterial stenosis, avoiding the onset of stroke. The periprocedural and long-term complications include implantation failure, intracranial bleeding, vessel rupture, embolism and in-stent restenosis. Medical treatment with anticoagulant drugs in periprocedural stage may prevent for the happening of complications.
Genetic Diversity and Population Structure of Siberian apricot (Prunus sibirica L.) in China
Ming Li,Zhong Zhao,Xingjun Miao,Jingjing Zhou
International Journal of Molecular Sciences , 2014, DOI: 10.3390/ijms15010377
Abstract: The genetic diversity and population genetic structure of 252 accessions from 21 Prunus sibirica L. populations were investigated using 10 ISSR, SSR, and SRAP markers. The results suggest that the entire population has a relatively high level of genetic diversity, with populations HR and MY showing very high diversity. A low level of inter-population genetic differentiation and a high level of intra-population genetic differentiation was found, which is supported by a moderate level of gene flow, and largely attributable to the cross-pollination and self-incompatibility reproductive system. A STRUCTURE (model-based program) analysis revealed that the 21 populations can be divided into two main groups, mainly based on geographic differences and genetic exchanges. The entire wild Siberia apricot population in China could be divided into two subgroups, including 107 accessions in subgroup (SG) 1 and 147 accessions in SG 2. A Mantel test revealed a significant positive correlation between genetic and geographic distance matrices, and there was a very significant positive correlation among three marker datasets. Overall, we recommend a combination of conservation measures, with ex situ and in situ conservation that includes the construction of a core germplasm repository and the implement of in situ conservation for populations HR, MY, and ZY.
Electronic transport of a large scale system studied by renormalized transfer matrix method: application to armchair graphene nanoribbons between quantum wires
Miao Gao,Gui-Ping Zhang,Zhong-Yi Lu
Physics , 2013, DOI: 10.1016/j.cpc.2013.12.006
Abstract: Study on the electronic transport of a large scale two dimensional system by the transfer matrix method (TMM) based on the Sch\"{o}rdinger equation suffers from the numerical instability. To address this problem, we propose a renormalized transfer matrix method (RTMM) by setting up a set of linear equations from U times of multiplication of traditional transfer matrix (U=N/S}with N and S being the atom number of length and the transfer step), and smaller S is required for wider systems. Then we solve the above linear equations by Gauss elimination method and further optimize to reduce the computational complexity from O(U^3M^3) to O(UM^3), in which M is the atom number of the width. Applying RTMM, we study transport properties of large scale pure and long-range correlated disordered armchair graphene nanoribbon (AGR) (carbon atoms up to 10^6 for pure case) between quantum wire contacts. As for pure AGR, the conductance is superlinear with the Fermi energy and the conductance is linear with the width while independent of the length, showing characteristics of ballistic transport. As for disordered AGR with long-range correlation, there is metal-insulator transition induced by the correlation strength of disorder. It is straightforward to extend RTMM to investigate transport in large scale system with irregular structure.
Investigation of atomic and electronic structures of MgOFeSe studied by the first-principles calculations
Kai Liu,Miao Gao,Zhong-Yi LU,Tao Xiang
Physics , 2013,
Abstract: In order to assist the search of new superconductors in iron selenide materials by intercalation, we calculate the crystal and electronic structures of MgOFeSe using the first-principles density functional theory. MgOFeSe is isotructural to the parent compound of iron pnictide superconductor LaOFeAs. In LaOFeAs, the anion O$^{2-}$ is located at the center of each LaO tetrahedra. But for MgOFeSe, we find that the crystal structure with the cation Mg$^{2+}$ as the tetrahedral center in the MgO layer is energetically more stable. The low energy band structures around the Fermi surfaces of MgOFeSe are contributed mainly by Fe 3$d$ orbitals. The ground state of MgOFeSe is collinearly antiferromagnetically ordered. The height of Se atoms above the Fe-Fe layer is about 1.38 \AA, which is close to the height of As from the Fe-Fe layer in the iron pnictide superconductors with optimal superconducting transition temperatures.
Atomic and electronic structures of ternary iron arsenides $A$Fe$_2$As$_2$(001) surfaces ($A$=Ba, Sr, or Ca)
Miao Gao,Fengjie Ma,Zhong-Yi Lu,Tao Xiang
Physics , 2009, DOI: 10.1103/PhysRevB.81.193409
Abstract: By the first-principles electronic structure calculations, we find that energetically the most favorable cleaved $A$Fe$_2$As$_2$(001) surface ($A$=Ba, Sr, or Ca) is $A$-terminated with a $(\sqrt{2}\times \sqrt{2})R45^{\circ}$ or $(1\times 2)$ order. The $(1\times 2)$ ordered structure yields a $(1\times 2)$ dimerized STM image, in agreement with the experimental observation. The $A$ atoms are found to diffuse on the surface with a small energy barrier so that the cleaving process may destroy the $A$ atoms ordering. At the very low temperatures this may result in an As-terminated surface with the $A$ atoms in randomly assembling. The As-terminated BaFe$_2$As$_2$ surface in orthorhombic phase is $(\sqrt{2}\times\sqrt{2})R45^{\circ}$ buckled, giving rise to a switchable $(\sqrt{2}\times \sqrt{2})R45^{\circ}$ STM pattern upon varying the applied bias. No any reconstruction is found for the other As-terminated surfaces. There are surface states crossing or nearby the Fermi energy in the As-terminated and $(1\times 2)$ $A$-terminated surfaces. A unified physical picture is thus established to help understand the cleaved $A$Fe$_2$As$_2$(001) surfaces.
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