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Search Results: 1 - 10 of 11105 matches for " Meihong Ye "
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Research on Strengthening Tax Follow-Up Management and Preventing Tax Law Enforcement Risks in the Context of Simplified Administration and Power Decentralization  [PDF]
Meihong Li, Hanchun Wei
Journal of Financial Risk Management (JFRM) , 2016, DOI: 10.4236/jfrm.2016.54026
Abstract: This paper summarizes and analyzes the problems existing in the follow-up management and tax law enforcement in the context of function transformation of tax authorities, simplified administration and power decentralization, and discusses the approach to strengthen the follow-up management and prevent the tax law enforcement risk.
Protective Effect of Corn Oligopeptides on Acute Alcoholism in Rodent Models
Feng Zhang,Jiali Zhang,Meihong Xu,Xiaoqian Dai,Yujie Li,Ye Ding,Zhaofeng Zhang,Yong Li
Journal of Animal and Veterinary Advances , 2012, DOI: 10.3923/javaa.2012.2070.2074
Abstract: The present study aimed to investigate the effects of Corn Oligopeptides (COP) on acute alcoholism in rat models. Female SD rats were randomly assigned to 4 groups per test including control group and 3 COP intervention groups (2.25, 4.5 and 9 g/kg/BW). About 5 g/kg/BW ethanol (8 g/kg/BW for loss of righting reflex test) was given intragastricly 10 min before COP treatment. Ethanol levels in blood, behavioral studies and ADH activity in liver were assayed. Researchers found that COP treatment could promote the alcohol metabolism and correct the movement disorder caused by alcohol consumption to some extent. However, the ADH levels had no changes among different groups. These findings suggest that COP have a protective effect on acute alcoholism in rats.
A Comparison of Business Negotiation Behavior between Korea and China
Meihong Sun
International Journal of Business and Management , 2009, DOI: 10.5539/ijbm.v4n12p212
Abstract: With the establishment of Korea and China’s diplomatic relationship in 1992, the business activities between Korea and China show the trend of booming during this decade; these two countries have become close trading partners to each other. The process from “strangers” to close friends in business just happened during this decade. The reason why these two countries have been so close in business is because of the geographic advantage and similar cultural roots, Confucianism. Though these two countries have similar cultural roots, due to different social backgrounds, there are still differences in their business cultures. Therefore, this paper picks negotiation as the core and does some comparisons about negotiation behavior between Koreans and Chinese, aiming to provide some useful reminders when conducting business activities in these two countries, for negotiation is the constant factor in business life.
Ceramide Mediates Ox-LDL-Induced Human Vascular Smooth Muscle Cell Calcification via p38 Mitogen-Activated Protein Kinase Signaling
Lizhen Liao, Qin Zhou, Yan Song, Weikang Wu, Huimin Yu, Sheng Wang, Yanling Chen, Meihong Ye, Lihe Lu
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0082379
Abstract: Vascular calcification is associated with significant cardiovascular morbidity and mortality, and has been demonstrated as an actively regulated process resembling bone formation. Oxidized low density lipoprotein (Ox-LDL) has been identified as a regulatory factor involved in calcification of vascular smooth muscle cells (VSMCs). Additionally, over-expression of recombinant human neutral sphingomyelinase (N-SMase) has been shown to stimulate VSMC apoptosis, which plays an important role in the progression of vascular calcification. The aim of this study is to investigate whether ceramide regulates Ox-LDL-induced calcification of VSMCs via activation of p38 mitogen-activated protein kinase (MAPK) pathway. Ox-LDL increased the activity of N-SMase and the level of ceramide in cultured VSMCs. Calcification and the osteogenic transcription factor, Msx2 mRNA expression were reduced by N-SMase inhibitor, GW4869 in the presence of Ox-LDL. Usage of GW4869 inhibited Ox-LDL-induced apoptosis in VSMCs, an effect which was reversed by C2-ceramide. Additionally, C2-ceramide treatment accelerated VSMC calcification, with a concomitant increase in ALP activity. Furthermore, C2-ceramide treatment enhanced Ox-LDL-induced VSMC calcification. Addition of caspase inhibitor, ZVAD-fmk attenuated Ox-LDL-induced calcification. Both Ox-LDL and C2-ceramide treatment increased the phosphorylation of p38 MAPK. Inhibition of p38 MAPK by SB203580 attenuated Ox-LDL-induced calcification of VSMCs. These data suggest that Ox-LDL activates N-SMase-ceramide signaling pathway, and stimulates phosphorylation of p38 MAPK, leading to apoptosis in VSMCs, which initiates VSMC calcification.
Steady State Solution and Stability of an Age-Structured MSIQR Epidemic Model  [PDF]
Meihong Qiao, Huan Qi, Tianhai Tian
Intelligent Information Management (IIM) , 2010, DOI: 10.4236/iim.2010.25037
Abstract: The importance of epidemiology in our life has stimulated researchers to extend the classic Susceptibles-Infectives-Removed (SIR) model to sophisticated models by including more factors in order to give detailed transmission dynamics of epidemic diseases. However, the integration of the quarantine policy and age-structure is less addressed. In this work we propose an age-structured MSIQR (temporarily immune-susceptibles-infectives-quarantined-removed) model to study the impact of quarantine policies on the spread of epidemic diseases. Specifically, we investigate the existence of steady state solutions and stability property of the proposed model. The derived explicit expression of the basic reproductive number shows that the disease-free equilibrium is globally asymptotically stable if, and that the unique endemic equilibrium exists if. In addition, the stability conditions of the endemic equilibrium are derived.
Meihong Hu,Shishen Zhang
Acta Crystallographica Section E , 2009, DOI: 10.1107/s1600536809027044
Abstract: In the crystal structure of the centrosymmetric title compound, [Zn2Cl4(C14H14N4)2], the ZnII atom is coordinated by two N atoms from two 1,2-bis(imidazol-1-ylmethyl)benzene ligands and two Cl atoms to confer a distorted tetrahedral geometry at the metal center.
Study on the Mathematical Thinking Ability in College Education
Meihong Qiao,Anping Liu
Education Research Frontier , 2013,
Abstract: The critical aspect of cultivating mathematical ability is the training of mathematics thinking. In the process of mathematics education, it should coach the creative thinking continually, and College mathematics will play an important role in training students’ thinking ability. As the matter of fact, mathematics can explain many phenomena simply and accurately. Through the living feeling, leading students to study these things, which can form the habit of being happy to analyze mathematics and communicate with each other. It could strengthen students’ awareness of applying mathematics and improve the ability of using mathematics. According to three effective ways of coaching students, in order to apply mathematic knowledge in all kinds of social topics, the author will study how to train student’s mathematical thinking from the perspective of college mathematical teaching in this topic.
Role of Human Endogenous Retroviral Long Terminal Repeats (LTRs) in Maintaining the Integrity of the Human Germ Line
Meihong Liu,Maribeth V. Eiden
Viruses , 2011, DOI: 10.3390/v3060901
Abstract: Retroviruses integrate a reverse transcribed double stranded DNA copy of their viral genome into the chromosomal DNA of cells they infect. Occasionally, exogenous retroviruses infect germ cells and when this happens a profound shift in the virus host dynamic occurs. Retroviruses maintained as hereditable viral genetic material are referred to as endogenous retroviruses (ERVs). After millions of years of co-evolution with their hosts many human ERVs retain some degree of function and a few have even become symbionts. Thousands of copies of endogenous retrovirus long terminal repeats (LTRs) exist in the human genome. There are approximately 3000 to 4000 copies of the ERV-9 LTRs in the human genome and like other solo LTRs, ERV-9 LTRs can exhibit distinct promoter/enhancer activity in different cell lineages. It has been recently reported that a novel transcript of p63, a primordial member of the p53 family, is under the transcriptional control of an ERV-9 LTR [1]. The expression of different p63 transcript isoforms has been previously shown to have an important role in replenishing cutaneous epithelial stem cells and maintaining the fidelity of the female germ line [2]. In this recent report, a novel p63 transcript, designated GTAp63, is described as specifically expressed in healthy human testes and germ cell precursors of human testes but not in testicular cancer cells. The ability of ERV-9 regulatory regions to contribute to the maintenance of male germ line stability is yet another example of how ERVs have evolved to serve an important function in the physiology of their human hosts.
The receptors for gibbon ape leukemia virus and amphotropic murine leukemia virus are not downregulated in productively infected cells
Meihong Liu, Maribeth V Eiden
Retrovirology , 2011, DOI: 10.1186/1742-4690-8-53
Abstract: We used replication-competent GFP-expressing viruses containing either an amphotropic murine leukemia virus (A-MLV) or the gibbon ape leukemia virus (GALV) envelope. We also constructed similar viruses containing fluorescence-labeled Gag proteins for the detection of viral particles. Using this repertoire of reagents together with a wide range of antibodies, we were able to determine the presence and availability of viral receptors, and detect viral envelope proteins and particles presence on the cell surface of chronically infected cells.A-MLV or GALV receptors remain on the surface of chronically infected cells and are detectable by respective antibodies, indicating that these receptors are not downregulated in these infected cells as previously proposed. We were also able to detect viral envelope proteins on the infected cell surface and infected cells are unable to bind soluble A-MLV or GALV envelopes indicating that receptor binding sites are masked by endogenously expressed A-MLV or GALV viral envelope. However, receptor masking does not completely prevent A-MLV or GALV superinfection.Rubin and co-workers discovered, many years ago, that chicken embryos productively infected with Rous Sarcoma Virus (RSV) were resistant to subsequent RSV challenge [1]. This phenomenon was designated as viral superinfection interference. It was later shown that chicken embryos productively infected by RSV were resistant to avian leukosis virus [2]. It is now well established that resistance to superinfection occurs among many genera of retroviruses [3]. Cells productively infected with gammaretroviruses are resistant to challenge infection. This is thought to occur because primary viral envelope expression prevents superinfection by interfering with the binding of viruses that recognize the same receptor. It remains unclear how access of most gammaretroviruses to their receptors are blocked; in superinfection specifically, it is unclear whether the envelope protein interacts wit
A mutant retroviral receptor restricts virus superinfection interference and productive infection
Meihong Liu, Maribeth V Eiden
Retrovirology , 2012, DOI: 10.1186/1742-4690-9-51
Abstract: In this study we analyzed the binding affinity of the mutant receptor PiT2K522E and determined that it has a 1000 fold decreased GALV envelope binding affinity compared to the GALV wild type receptor. The decreased affinity does not restrict the initiation of cell-free GALV infection. The diminished binding affinity does, however, correlate with a decrease in the ability of GALV to spread in cells expressing this mutant receptor.The reduced ability of GALV to subsequently spread among cells expressing PiT2K522E is likely resulted from reduced cell-cell transmission, the decreased ability of PiT2K522E-expressing cells to establish superinfection interference, and attendant cytopathic affects.
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