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Search Results: 1 - 10 of 2655 matches for " Masato Abe "
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Stainability and Fine Structure of Intracytoplasmic Inclusion Bodies in the Locus Ceruleus of Mouse  [PDF]
Yoshimitsu Y. Katoh, Kazuyoshi Sakai, Chiyuki Kaneko, Masato Abe
Journal of Behavioral and Brain Science (JBBS) , 2013, DOI: 10.4236/jbbs.2013.37058
Abstract: The present study compared intracytoplasmic inclusion bodies in the locus ceruleus (LC) of mouse with protein bodies in the LC of human. Phosphotungstic acid-hematoxylin (PTAH) and the Mallory method were used as the anionic stains. The inclusion bodies and protein bodies, which stained with PTAH and the Mallory method in the brain, contain proteins that appear to belong to the same family. Although both inclusion and protein bodies were formed with the same arginine composition, their distribution in the brain was similar and similar physiological changes by morbidity were observed, and the fine structure of the inclusion bodies and protein bodies appeared to be different. The present findings suggest that mouse inclusion bodies and human protein bodies are different.
The Perineal Membrane: Its Composite Fibers and Nerve Content, and Relationship to the Levator Ani and Deep Transverse Perineal Muscles  [PDF]
Tetsuji Kurokawa, Nobuyuki Hinata, Hiromasa Sasaki, Gen Murakami, Masato Fujisawa, Shin-Ichi Abe, Yoshio Yosida
Open Journal of Obstetrics and Gynecology (OJOG) , 2014, DOI: 10.4236/ojog.2014.47061

The perineal membrane (PM) is a thick, elastic fiber-rich, smooth muscle-poor membrane extending along the vestibule and lower vaginal wall and embedding the urethrovaginal sphincter and compressor urethrae muscles. To provide a better understanding of the topographical relationship between the PM and the levator ani muscle, we examined histological sections from 15 female cadavers. The composite fibers of the PM were usually continuous with that of a fascia covering the inferior or lateral surface of the levator ani (fascia diaphragmatis pelvis inferior) rather than the endopelvic fascia covering the superior or medial surface of the latter muscle. However, this fascial connection was sometimes interrupted by a venous plexus. The deep transverse perineal muscle was consistently adjacent to the posterolateral aspect of the PM, but whether it extended superficially or deeply to the PM depended on size of the muscle. In contrast to the endopelvic fascia embedding abundant middle-sized nerves (cavernous and sphincter nerves; 0.05 - 0.1 mm in thickness), the PM contained very thin nerves: many in 10 cadavers but few in 5 cadavers. Most of the nerves seemed to be sensory on the basis of immunohistochemistry. The levator ani muscle was considered likely to provide traction force to the PM, but active elevation appeared to be difficult because of the highly elastic nature of the PM and the interrupting venous plexus. Loss of nerves in the PM might be one of a number of factors that can accelerate pelvic organ prolapse.

Effect of the Suppression of Cariesitic Bacterial Growth and Biofilm Formation Using Hydrogen/Free Chlorine Mixed Water Produced by an Electrolysis-Type Hydrogen Generator  [PDF]
Ryusuke Suzuki, Rin Kaneko, Masaru Nakano, Masato Kanda, Yuji Sebata, Shota Motegi, Tomoko Abe, Kazuaki Muramatsu
Health (Health) , 2019, DOI: 10.4236/health.2019.112013
Abstract: OBJECTS: Hydrogen has been shown to possess antibacterial effects at high concentrations. In addition, chlorine has a strong bactericidal effect even at low concentrations. Electrolysis is a way to simultaneously generate these two components. However, the concentration of hydrogen/free chlorine mixed water generated through electrolysis decreases quickly. It is predicted that the concentration of hydrogen/free chlorine mixed water will vary depending on the quality of water used. After investigating the optimum generation conditions, the effects of the most stable concentration of hydrogen/free chlorine mixed water on carious tooth fungus were evaluated in vitro. Thus, in this experiment, our goal was to evaluate the effects of hydrogen/free chlorine mixed water on oral bacteria. MATERIALS AND METHODS: Using a device that generates hydrogen/free chlorine through electrolysis, the differences in the concentrations of hydrogen and free chlorine based on electrolysis time were evaluated using tap water. Additionally, various concentration changes due to electrolysis time on the hydrogen/free chlorine mixed water were evaluated. Distilled tap water as a control group, hydrogen/free chlorine mixed water, and commercially available mouthwash were added for 1 minute to cultured Streptococcus mutans and then rinsed out with the culture medium. Bacterial growth (600 nm) and biofilm formation (590 nm) were measured at 3 and 6 hours after the addition of the medium. RESULTS: The concentration of hydrogen/chlorine mixed water produced by electrolysis varied depending on electrolysis time and the water used. The inhibitory effect of bacterial growth was enhanced depending on the chlorine concentration. Regarding the inhibitory effect on biofilm formation, only the mixed water of hydrogen/free chlorine concentration (500 ppb - 1.0 mg/L) had a suppressing effect after 6 hours. CONCLUSION: It was suggested that hydrogen/chlorine mixed water can be easily produced by electrolysis and has the effect of suppressing the growth of dental caries; therefore, it could be used as a cleaning agent in oral care products.
Developing an Internet Oriented Platform for Earthquake Engineering Application and Web-based Virtual Reality Simulation System for Seismic hazards: Towards Disaster Mitigation in Metropolises
Ali Alaghehbandian,Ping Zhu,Masato Abe,Junji Kiyono
Journal of Systemics, Cybernetics and Informatics , 2003,
Abstract: This paper reviews the state of the art on risk communication to the public, with an emphasis on simulation of seismic hazards using VRML. Rapid growth computer technologies, especially the Internet provide human beings new measures to deal with engineering and social problems which were hard to solve in traditional ways. This paper presents a prototype of an application platform based on the Internet using VR (Virtual Reality) for civil engineering considering building an information system of risk communication for seismic hazards and at the moment in the case of bridge structure.
Global network structure of dominance hierarchy of ant workers
Hiroyuki Shimoji,Masato S. Abe,Kazuki Tsuji,Naoki Masuda
Computer Science , 2014,
Abstract: Dominance hierarchy among animals is widespread in various species and believed to serve to regulate resource allocation within an animal group. Unlike small groups, however, detection and quantification of linear hierarchy in large groups of animals are a difficult task. Here, we analyse aggression-based dominance hierarchies formed by worker ants in Diacamma sp. as large directed networks. We show that the observed dominance networks are perfect or approximate directed acyclic graphs, which are consistent with perfect linear hierarchy. The observed networks are also sparse and random but significantly different from networks generated through thinning of the perfect linear tournament (i.e., all individuals are linearly ranked and dominance relationship exists between every pair of individuals). These results pertain to global structure of the networks, which contrasts with the previous studies inspecting frequencies of different types of triads. In addition, the distribution of the out-degree (i.e., number of workers that the focal worker attacks), not in-degree (i.e., number of workers that attack the focal worker), of each observed network is right-skewed. Those having excessively large out-degrees are located near the top, but not the top, of the hierarchy. We also discuss evolutionary implications of the discovered properties of dominance networks.
Real-time imaging and analysis of differences in cadmium dynamics in rice cultivars (Oryza sativa) using positron-emitting107Cd tracer
Satoru Ishikawa, Nobuo Suzui, Sayuri Ito-Tanabata, Satomi Ishii, Masato Igura, Tadashi Abe, Masato Kuramata, Naoki Kawachi, Shu Fujimaki
BMC Plant Biology , 2011, DOI: 10.1186/1471-2229-11-172
Abstract: Imaging and quantitative analyses revealed the different patterns in time-varying curves of Cd amounts in the roots of rice cultivars tested. Three low-Cd accumulating cultivars (japonica type) showed rapid saturation curves, whereas three high-Cd accumulating cultivars (indica type) were characterized by curves with a peak within 30 min after107Cd supplementation, and a subsequent steep decrease resulting in maintenance of lower Cd concentrations in their roots. This difference in Cd dynamics may be attributable to OsHMA3 transporter protein, which was recently shown to be involved in Cd storage in root vacuoles and not functional in the high-Cd accumulating cultivars. Moreover, the PETIS analyses revealed that the high-Cd accumulating cultivars were characterized by rapid and abundant Cd transfer to the shoots from the roots, a faster transport velocity of Cd to the panicles, and Cd accumulation at high levels in their panicles, passing through the nodal portions of the stems where the highest Cd intensities were observed.This is the first successful visualization and quantification of the differences in whole-body Cd transport from the roots to the grains of intact plants within rice cultivars that differ in grain Cd concentrations, by using PETIS, a real-time imaging method.Cadmium (Cd) has an important impact on agriculture, as the excessive consumption of Cd from contaminated food crops can lead to toxicity in humans. High-dose Cd exposure is particularly toxic to the kidney and leads to renal proximal tubular dysfunction [1]. In Japan, itai-itai disease (renal osteomalacia), which is characterized by complaints of spinal and leg bone pain, was recognized as a type of chronic toxicity induced by excess Cd contamination of drinking water and cereals (mainly rice). Since then, the contamination of rice by Cd has been monitored to prevent it from being distributed to consumers in Japan, in accordance with the Food Sanitation Act established in 1969 in Japan. Neve
Membrane Protein Location-Dependent Regulation by PI3K (III) and Rabenosyn-5 in Drosophila Wing Cells
Masato Abe, Yuka Setoguchi, Tsubasa Tanaka, Wakae Awano, Kuniaki Takahashi, Ryu Ueda, Akira Nakamura, Satoshi Goto
PLOS ONE , 2009, DOI: 10.1371/journal.pone.0007306
Abstract: The class III phosphatidylinositol-3 kinase (PI3K (III)) regulates intracellular vesicular transport at multiple steps through the production of phosphatidylinositol-3-phosphate (PI(3)P). While the localization of proteins at distinct membrane domains are likely regulated in different ways, the roles of PI3K (III) and its effectors have not been extensively investigated in a polarized cell during tissue development. In this study, we examined in vivo functions of PI3K (III) and its effector candidate Rabenosyn-5 (Rbsn-5) in Drosophila wing primordial cells, which are polarized along the apical-basal axis. Knockdown of the PI3K (III) subunit Vps15 resulted in an accumulation of the apical junctional proteins DE-cadherin and Flamingo and also the basal membrane protein β-integrin in intracellular vesicles. By contrast, knockdown of PI3K (III) increased lateral membrane-localized Fasciclin III (Fas III). Importantly, loss-of-function mutation of Rbsn-5 recapitulated the aberrant localization phenotypes of β-integrin and Fas III, but not those of DE-cadherin and Flamingo. These results suggest that PI3K (III) differentially regulates localization of proteins at distinct membrane domains and that Rbsn-5 mediates only a part of the PI3K (III)-dependent processes.
Genetic diversity of arsenic accumulation in rice and QTL analysis of methylated arsenic in rice grains
Masato Kuramata , Tadashi Abe , Akira Kawasaki, Kaworu Ebana, Taeko Shibaya, Masahiro Yano and Satoru Ishikawa
Rice , 2013, DOI: 10.1186/1939-8433-6-3
Abstract: Based on the results provided, one strategy for developing rice cultivars with a low level of toxic As would be to change the proportion of organic As on the basis of a low level of total As content.
The Effect of the Pressure for the Formation of YBa2Cu3O7–d Bulk Ceramics with Domestic Microwave Oven  [PDF]
Masato Ohmukai
Engineering (ENG) , 2011, DOI: 10.4236/eng.2011.311136
Abstract: We fabricated YBa2Cu3O7–d bulk ceramics with a domestic microwave oven and investigated the effect of pressure at the press procedure. If the pressure was not high enough, the ratio of BaCuO2 phase became large, estimated from x-ray diffraction (XRD) measurements. We found that the pressure should be 700 kgf/cm2 at least in order to suppress the BaCuO2 phase.
Effects of Beam Startup Characteristics on Dose Delivery Accuracy at Low Monitor Units in Step-and-Shoot Intensity Modulated Radiation Therapy  [PDF]
Kazunori Fujimoto, Kunihiko Tateoka, Yuji Yaegashi, Katsumi Shima, Junji Suzuki, Yuichi Saito, Akihiro Nakata, Takuya Nakazawa, Tadanori Abe, Masaki Yano, Masanori Someya, Kensei Nakata, Masakazu Hori, Masato Hareyama, Koichi Sakata
International Journal of Medical Physics,Clinical Engineering and Radiation Oncology (IJMPCERO) , 2013, DOI: 10.4236/ijmpcero.2013.21001

Intensity modulated radiation therapy (IMRT) is a highly accurate technique that is usually implemented in either dynamic or step-and-shoot fashion with many segments each having low monitor units (MUs). The present study evaluated the effects of beam startup characteristics on the dose delivery accuracy for each segment at low MUs for step-and-shoot IMRT with an Elekta Precise accelerator at the highest dose rates. We used a two-dimensional semi-conductor detector for the dose measurements. The field size of each segment was assumed to be 20 ×20 cm2 and each segment was set to deliver 1 - 10 MUs. Our results show a variation in dose delivery accuracy between segments for the same IMRT beam, which can be attributed to the beam startup characteristics. This variability is attributed to the changes in the transient changes in the temperatures of the electron gun filament and the magnetron. That is, the transient increase in the temperature of the filament leads to increasing doses with time and that of the magnetron leads to decreasing doses with time during the first few MUs.

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