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Search Results: 1 - 10 of 26601 matches for " Martin;Coulibaly "
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Critique of John Locke Objection to the Innate Ideas  [PDF]
Coulibaly Yacouba
Open Journal of Philosophy (OJPP) , 2016, DOI: 10.4236/ojpp.2016.64030
Abstract: The debate about innetivism is not a new subject in philosophy. From the earlier philosophers up to the recent ones, the main question that remains is: men are born with some ideas or we only know through experience? In this study, the emphasis will not be the process of human knowledge but the controversy in the objection of Locke to the innate Idea. From the beginning of his objection, John Locke shows that we are born with empty mind. Then through experience we build the knowledge little by little. But later on, Locke recognizes that it’s also possible that children may have some ideas from the womb. They may experience wants, diseases, hunger, and heat. To him many of those ideas which were produced in the minds of children, in the beginning of their sensation, if they are not repeated in future, then they are quite lost. If we choose the fact that people are born with ideas from pre-experience, that view is more scientific and more logical than the religious view of Plato. The paper concludes that even though there is no complete agreement on how innate ideas are made, we did not come in the world with blank mind and what is important is not how innate ideas have been made but their existence and application in life.
Enzyme Inhibition Effect and Polyphenolic Content of Medicinal Plant Extracts from Burkina Faso
Mindiediba Jean Bangou,Martin Kiendrebeogo,Moussa Compaore,Ahmed Yacouba Coulibaly
Journal of Biological Sciences , 2011,
Abstract: In the present study, 36 plant extracts, belonging to 6 families from Burkina Faso were used to evaluate their glutathione-S-transferase (GST), acetylcholinesterase (AChE), carboxylesterase (CES) and xanthine oxidase (XO) inhibitory activities and their phenolic, tannin and flavonoids contents by using spectrophotometrical methods. At 100 μg mL-1, Lippia chevalieri, Eclipta prostrata, Lantana camara and Indigofera pulchra extracts showed the best percentage of inhibition by regulating GST, AChE, CES and XO activities, respectively. The phytochemical investigations showed that all plant extracts were rich in biological compounds, namely phenolic, tannin and flavonoids. Particularly Cassia mimosoides extract presented the best phenolic, tannin and flavonoid contents. This result indicated that phenolic from Ceasalpiniaceae, flavonoids from Combretaceae and tannin from Verbenaceae contribute significantly to the inactivation of CES, AchE and GST, respectively. However, no significant correlation was found between polyphenolic compounds content and XO inhibitory activity. Present findings could partially justify the traditional uses of these plants in the treatment of mental disorders, gout, painful inflammations and cardiovascular diseases.
From the Failure of African Socialism, How to Set a New Trend for a New Generation?  [PDF]
Coulibaly Yacouba, Belko Wologueme
Open Journal of Social Sciences (JSS) , 2018, DOI: 10.4236/jss.2018.62003
Abstract:
From 1960, most of the African nations got their political independence. Many countries started to establish national and regional vision about the future. Then some political scientist, state men and scholars came out with a new philosophy called socialism. The concept of socialism was at the same time philosophical and ideological conviction made to promote national and regional unity in Africa. Unfortunately, the concept was misunderstood by most of the leaders to some extent, but also, the lack of good will led some others to mislead their own people by fighting against the idea of socialism. The fact that many Africans were not educated, contributed to the growth and expansion of socialism with effectiveness. For all these reasons, the application of socialism was difficult, even impossible. In this article, we are trying to explain the main reason of the failure of this political and philosophical thought and set a new trend for the new generation.
Evaluation of Enzymes Inhibition Activities of Medicinal Plant from Burkina Faso
Mindiediba Jean Bangou,Martin Kiendrebeogo,Nag-Tiero Roland Meda,Ahmed Yacouba Coulibaly
Pakistan Journal of Biological Sciences , 2011,
Abstract: The aim of the present study was to evaluate some enzymes inhibitory effects of 11 plant species belonging to 9 families from Burkina Faso. Methanolic extracts were used for their Glutathione-s-transferase (GST), Acetylcholinesterase (AChE), Carboxylesterase (CES) and Xanthine Oxidase (XO) inhibitory activities at final concentration of 100 μg mL-1. The total phenolics, flavonoids and tannins were also determined spectrophotometrically using Folin-Ciocalteu, AlCl3 and ammonium citrate iron reagents, respectively. Among the 11 species tested, the best inhibitory percentages were found with Euphorbia hirta, Sclerocarya birrea and Scoparia dulcis (inhibition>40%) followed by Annona senegalensis, Annona squamosa, Polygala arenaria and Ceratotheca sesamoides (inhibition>25%). The best total phenolic and tannin contents were found with S. birrea with 56.10 mg GAE/100 mg extract and 47.75 mg TAE/100 mg extract, respectively. E hirta presented the higher total flavonoids (9.96 mg QE/100 mg extract). It's was found that Sclerocarya birrea has inhibited all enzymes at more than 30% and this activity is correlated to total tannins contents. Contrary to S. birrea, the enzymatic activities of E. hirta and S. dulcis are correlated to total flavonoids contents. Present findings suggest that the methanolic extracts of those plant species are potential inhibitors of GST, AChE, CES and XO and confirm their traditional uses in the treatment of mental disorders, gout, painful inflammations and cardiovascular diseases.
Antiacetylcholinesterase and antioxidant activity of essential oils from six medicinal plants from Burkina Faso
Martin Kiendrebeogo,Ahmed Y. Coulibaly,Roger C. H. Nebie,Boukaré Zeba
Revista Brasileira de Farmacognosia , 2011,
Abstract: In this investigation, we evaluated essential oils from six medicinal plants from Burkina Faso for their antiacetylcholinesterase and antioxidant abilities. The chemotype of most active were also determined. The best antiacetylcholinesterase activities were recorded for the essential oils of Eucalyptus camaldulensis (IC50 18.98 μ g/mL) and Ocimum canum (IC50 36.16 μ g/mL). Their chemotype have been related to the 1,8-cineole one. Both essential oils demonstrated a linear mixed non competitive inhibition. The essential oil of Ocimum basilicum which belong to the linalool-eugenol chemotype exhibited the best radical scavenging activity (IC50 3.82 μ g/mL) and reducing power (531.75 mg AAE/g). In comparison with gallic and ascorbic acids, O. basilicum essential oil evidenced interesting antioxidant activities. The antiacetylcholinesterase and antioxidant activities of essential oils were discussed in regard with their chemical composition.
Common Behavior in the Practice of Democracy in Africa  [PDF]
Coulibaly Yacouba, Traore Sanibe Emmanuel
Open Journal of Political Science (OJPS) , 2017, DOI: 10.4236/ojps.2017.71002
Abstract: Africa is a vast continent with such a diverse and complex culture, which requires us to be careful in our language as we discuss and debate about the continent. Thus, the question of democracy in Africa is nowadays a debate that divides very schematically the political scientists. For instance, it is when it comes to the identification of the beginning of democratization in the continent, the description of the level of advancement in the democratic practice or even the nature of democracy that the differences arise. Although one thing remains undisputable: the practice of democracy in Africa suffers from many problems such as, misunderstanding, violence, problem of adaptation, multiple numbers of political party. Africa is a vast continent with such a diverse and complex culture, which requires us to be careful in our language as we discuss and debate about the continent. Thus, the question of democracy in Africa is nowadays a debate that divides very schematically the political scientists. For instance, it is when it comes to the identification of the beginning of democratization in the continent, the description of the level of advancement in the democratic practice or even the nature of democracy that the differences arise. However, one thing remains undisputable: the practice of democracy in Africa suffers from many problems such as, misunderstanding, violence, problem of adaptation, multiple numbers of political party.
Migrants’ Remittances as a Source of Funding Local Development: Case of Burkinabè Migrants in C?te d’Ivoire  [PDF]
Zié Ballo, Coulibaly Okayo Alphonsine
Theoretical Economics Letters (TEL) , 2018, DOI: 10.4236/tel.2018.87091
Abstract: This paper examines the possibility of directing remittances from Burkinabè migrants to the municipalities of their home country through loans. The descriptive results indicate that 94% of Burkinabè migrants agree to lend to the municipalities of their country. The econometric results obtained using the Tobit model show that variables of interest and economic variables such as profit, economic development, poverty reduction and job creation do not influence loan consent to the municipalities. On the other hand, cultural variables such as community spirit, unity, and mutual support, belief in God, conformism, and gerontocracy explain agreement to lend.
Assessment of Wastewater Management and Health Impacts in African Secondary Cities: Case of Dimbokro (C?te D’Ivoire)  [PDF]
Sandotin Lassina Coulibaly, Drissa Sangaré, Sylvain Kouakou Akpo, Seydou Coulibaly, Habib Ben Bamba, Lacina Coulibaly
Journal of Geoscience and Environment Protection (GEP) , 2016, DOI: 10.4236/gep.2016.48002
Abstract: The majority of population growth in developing countries will occur in secondary cities where there is limited access to clean water and sanitation. Wastewater management priorities in these cities will be different from those in larger cities and developed countries. For this reason, it is important to assess wastewater management in these cities of sub-Saharan Africa. This study assessed clean water supply, wastewater and faecal sludge management and associated health risks in Dimbokro, C?te D’Ivoire. The study was performed in March 2015 in 12 neighborhoods with a total of 703 households. In these neighborhoods, the questions were addressed and discussed with household head. The study revealed that the households of the city were structured on three topology habitats: residential (5%), economic (42%) and evolutive or yards housing (53%). For water supply, 99.4% of the households used water from SODECI, the local public water supply network, while the remaining 0.6% of surveyed household obtained water from wells. Domestic wastewater, used for doing laundry, dishwashing and showering, was disposed of in the following ways: directly into the street (33%), septic tank (23%), backyards (18%), storm drain (16%), sewer network (6%), pit latrine (3%) or into soakaway (2%). In addition, untreated wastewater was sometimes discharged into the N’Ziriver by certain households. 52% of households surveyed emptied latrines manually and 48 % used mechanic drain services. The most frequent diseases occurring in the households were Malaria (63%), Diarrhoea (13%) and Typhoid fever (9%) in the households of the city. In the light of this study, the municipal authorities of Dimbokro should provide the city with wastewater systems that drain to a central outlet system where the waste-water?can be easily treated before final disposal for reuse in agriculture.
Situation a-didactique et dispositif d’apprentissage instrumenté : cas de construction de projets de service
Bernard Coulibaly
Questions Vives : Recherches en éducation , 2011, DOI: 10.4000/questionsvives.227
Abstract: Dans cette contribution nous tentons d’analyser une situation didactique instrumentée sur une plate forme d’apprentissage à distance, situation dans laquelle des étudiants de Master 2 professionnel sont invités à réaliser un projet de service fictif. Cet apprentissage s’opère en groupe de 3 à 4 étudiants et vise l’acquisition de compétences en matière de conduite de projet de service dans le domaine de l’ingénierie en milieu socio-éducatif. L’article analyse, à partir des traces d’interaction, le processus de construction de ces savoir-faire en management de projet. Il met en évidence les stratégies de contournement et d’adaptation que les étudiants élaborent pour échapper aux contraintes d’une situation didactique fondée sur un dispositif pédagogique instrumenté .Il permet ainsi de comprendre le r le que des apprenants peuvent jouer dans la conception d’une situation didactique. In this paper we analyze an instrumented didactic situation that takes place on a distance learning platform. In this situation students in a professional master’s degree curriculum are invited to create a fictitious service project. They have to achieve this task in groups of 3 to 4 students. The task aims at making students acquire competences in terms of project management in the field of educational engineering. The article analyzes the process of building these skills in project management from traces of interaction. It highlights the strategies of circumvention and adaptation that students develop to escape the constraints of a teaching situation based on an instrumented educational device. It helps understand the role that learners can play in the design of a teaching situation.
Expression of the cytochrome P450s, CYP6P3 and CYP6M2 are significantly elevated in multiple pyrethroid resistant populations of Anopheles gambiae s.s. from Southern Benin and Nigeria
Rousseau F Djouaka, Adekunle A Bakare, Ousmane N Coulibaly, Martin C Akogbeto, Hilary Ranson, Janet Hemingway, Clare Strode
BMC Genomics , 2008, DOI: 10.1186/1471-2164-9-538
Abstract: All mosquitoes sampled belonged to the M form of An. gambiae s.s. There were high levels of permethrin resistance in an agricultural area (Akron) and an urban area (Gbedjromede), low levels of resistance in mosquito samples from an oil contaminated site (Ojoo) and complete susceptibility in the rural Orogun location. The target site mutation kdrW was detected at high levels in two of the populations (Akron f = 0.86 and Gbedjromede f = 0.84) but was not detected in Ojoo or Orogun. Microarray analysis using the Anopheles gambiae detox chip identified two P450s, CYP6P3 and CYP6M2 up regulated in all three populations, the former was expressed at particularly high levels in the Akron (12.4-fold) and Ojoo (7.4-fold) populations compared to the susceptible population. Additional detoxification and redox genes were also over expressed in one or more populations including two cuticular pre-cursor genes which were elevated in two of the three resistant populations.Multiple resistance mechanisms incurred in the different breeding sites contribute to resistance to permethrin in Benin. The cytochrome P450 genes, CYP6P3 and CYP6M2 are upregulated in all three resistant populations analysed. Several additional potential resistance mechanisms were also identified that warrant further investigation. Metabolic genes were over expressed irrespective of the presence of kdr, the latter resistance mechanism being absent in one resistant population. The discovery that mosquitoes collected from different types of breeding sites display differing profiles of metabolic genes at the adult stage may reflect the influence of a range of xenobiotics on selecting for resistance in mosquitoes.National Malaria Control Programmes are becoming increasingly reliant on strategies targeting the mosquito vectors. These almost invariably involve the use of long lasting insecticide treated nets (LLINs) or indoor residual spraying (IRS). Unfortunately the emergence of mosquito populations capable of withsta
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