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Search Results: 1 - 10 of 42510 matches for " Marlene Ant?nia dos;Castro "
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Relationship between the morphologic alterations of vocal cords from adult autopsies and the cause of death
Salge Ana Karina Marques,Castro Eumenia Costa da Cunha,Ferraz Mara Lúcia Fonseca,Reis Marlene Antnia dos
Revista do Hospital das Clínicas , 2004,
Abstract: PURPOSE: The purpose of this study was to identify the possible alteration in the thickness of the epithelium basal membrane of the vocal cords and correlate it with the cause of death. METHOD: Larynxes collected from adult autopsies during the period of 1993 to 2001 were utilized. We used the hematoxylin-eosin and periodic acid-Schiff staining methods for the morphological and morphometric analysis. RESULTS: Sixty-six vocal cords were analysed; increased thickness was identified in 14 cases (21.2%), with equal proportions between the genders. Increased vocal-cord thickness was more frequent in patients of the white ethnicity (12 cases, 85.7%). Respiratory alterations were found in 10 (71.4%) of the cases with increased vocal-cord thickness. Of the patients that were maintained with mechanical ventilation before death, 7 (18.4%) had thickening of the basal membrane. Among the smokers, 9 (19.63%) had basal membrane thickening. CONCLUSION: No statistically significant differences were found between the cases in which the cause of death was related to respiratory diseases as compared to non-respiratory diseases and the thickening of the basal membrane of the vocal cords. However, new studies are needed in order to verify the etiopathogenesis of this thickening.
Doen?as infecciosas como causas de morte em idosos autopsiados
Oliveira, Flávia Aparecida de;Reis, Marlene Antnia dos;Castro, Eumênia Costa da Cunha;Cunha, Selma Freire de Carvalho da;Teixeira, Vicente de Paula Antunes;
Revista da Sociedade Brasileira de Medicina Tropical , 2004, DOI: 10.1590/S0037-86822004000100009
Abstract: the population aging in brazil was associated with the alterations in the morbimortality of the population. the aim of this study was to verify the causes of death and other pathological processes in autopsied elderly. the elderly with 60 years or more in the period from 1976 to 1998 represented 394 cases (24.4%). the age median was 69 years ranged from 60 to 120 years, being higher in the women (70.5 versus 68yrs;p<0.05). the male gender (67.5%), white color (69.8%), and the cardiovascular (43.7%) and infectious (31%) causes of death were dominate. in the malnourished (76.2%) it had association of pneumonia and cystitis, (p<0.05). arteriosclerosis (61.9%), and the chagasic (42.1%) and hypertensive cardiopathies (39.1%) were the most frequent processes. therefore, it was observed an overlapping of chronic-degenerative and infectious causes of death. this study shows the necessity to value of follow up of body mass index and of risk factors for the development of illness in aging patients like pneumonia.
Doen as infecciosas como causas de morte em idosos autopsiados
Oliveira Flávia Aparecida de,Reis Marlene Antnia dos,Castro Eumênia Costa da Cunha,Cunha Selma Freire de Carvalho da
Revista da Sociedade Brasileira de Medicina Tropical , 2004,
Abstract: O envelhecimento populacional no Brasil está associado às altera es na morbimortalidade da popula o. Nesse estudo, foi verificado as causas de morte e outros processos patológicos em idosos autopsiados. Os idosos com idade maior ou igual a 60 anos, no período de 1976 a 1998 representaram 394 casos (24,4%). A mediana da idade foi 69 (60 a 120) anos, sendo maior nas mulheres (70,5 versus 68 anos; p<0,05). O sexo masculino (67,5%), a cor branca (69,8%) e as causas de morte cardiovascular (43,7%) e infecciosa (31%) prevaleceram. A subnutri o (76,2%) estava associada à pneumonite e cistite, (p<0,05). A arteriosclerose (61,9%) e as cardiopatias chagásica (42,1%) e hipertensiva (39,1%) foram os processos mais freqüentes. Portanto, foi observado sobreposi o das causas de morte cr nico-degenerativas e infecciosas. Isso demonstra a necessidade de valorizar medidas como o acompanhamento do índice de massa corporal e dos fatores de risco para o desenvolvimento de doen as no envelhecimento, como a pneumonite.
Relationship between the morphologic alterations of vocal cords from adult autopsies and the cause of death
Salge, Ana Karina Marques;Castro, Eumenia Costa da Cunha;Ferraz, Mara Lúcia Fonseca;Reis, Marlene Antnia dos;Teixeira, Vicente de Paula Antunes;
Revista do Hospital das Clínicas , 2004, DOI: 10.1590/S0041-87812004000200003
Abstract: purpose: the purpose of this study was to identify the possible alteration in the thickness of the epithelium basal membrane of the vocal cords and correlate it with the cause of death. method: larynxes collected from adult autopsies during the period of 1993 to 2001 were utilized. we used the hematoxylin-eosin and periodic acid-schiff staining methods for the morphological and morphometric analysis. results: sixty-six vocal cords were analysed; increased thickness was identified in 14 cases (21.2%), with equal proportions between the genders. increased vocal-cord thickness was more frequent in patients of the white ethnicity (12 cases, 85.7%). respiratory alterations were found in 10 (71.4%) of the cases with increased vocal-cord thickness. of the patients that were maintained with mechanical ventilation before death, 7 (18.4%) had thickening of the basal membrane. among the smokers, 9 (19.63%) had basal membrane thickening. conclusion: no statistically significant differences were found between the cases in which the cause of death was related to respiratory diseases as compared to non-respiratory diseases and the thickening of the basal membrane of the vocal cords. however, new studies are needed in order to verify the etiopathogenesis of this thickening.
Widespread hematogenous metastases and Trousseau's syndrome in gastric adenocarcinoma
Santos, Vitorino Modesto dos;Rodrigues, Denise Bertulucci Rocha;Castro, Eumênia Costa da Cunha;Saldanha, Jo?o Carlos;Soares, Sheila;Teixeira, Vicente de Paula Antunes;Reis, Marlene Antnia dos;
Revista do Hospital das Clínicas , 2001, DOI: 10.1590/S0041-87812001000300005
Abstract: a case of widespread hematogenous metastases and trousseau's syndrome is reported in a 40 year-old white housewife with gastric cancer, presenting subdural hematoma, ecchymoses, epistaxis, stomach and uterine bleeding. after undergoing hematoma drainage, she was unsuccessfully treated with platelets, red blood cells, plasma cryoprecipitate transfusions, and antibiotics. necropsy disclosed gastric ring-signet adenocarcinoma invading the serous layer, with massive disseminated intravascular coagulation and systemic neoplastic embolism. multiple old and recent hyaline (rich in fibrin and platelets) microthrombi, and tumor emboli were observed in the bone marrow, meninges, liver, lungs, kidneys, lymph nodes, adrenals, thyroid, heart, pancreas, and ovaries (krukenberg tumor).
Influência das intercorrências maternas e fetais nos diferentes graus de corioamnionite
Machado, Juliana Reis;Rocha, Laura Penna;Barrilari, Sue Ellen Gon?alves;Pucci, Karla Roberta Martins;Reis, Marlene Antnia dos;Castro, Eumênia Costa da Cunha;Corrêa, Rosana Rosa Miranda;
Revista Brasileira de Ginecologia e Obstetrícia , 2012, DOI: 10.1590/S0100-72032012000400003
Abstract: purpose: to evaluate the influence of maternal complications, prematurity, fetal anthropometric parameters and conditions of the newborn on different degrees of chorioamnionitis. methods: we analyzed 90 placentas from deliveries performed at the general hospital of triangulo mineiro federal university with a diagnosis of inflammation in the anatomopathological exams. we reviewed the medical records to obtain relevant maternal and fetal information. the infections were classified as grade i - deciduitis; grade ii - chorioamnionitis; grade iii - chorioamnionitis and vasculitis; grade iv - neonatal sepsis and grade v - fetal death and pneumonitis. results: among the pregnant women analyzed, 50.0% had no complications, 15.0% had ruptured membranes, 15.0% urinary tract infection, 7.5% hypertensive disorders, 7.5% transvaginal infection, 5.0% hematogenous infection, and 11.1% other complications. more than a half the neonates were males and 72.2% were born at term. analysis of the degree of chorioamnionitis showed that 56.7% had grade i, 22.2% grade ii, 4.4% grade iii, 10.0% grade iv, and 6.7% grade v. data were analyzed statistically by the χ2 test for qualitative variables and by the spearman test for correlation analysis. the higher grades of chorioamnionitis were observed in cases of maternal complications. we observed negative correlations between all parameters and the degree of fetal chorioamnionitis, which were significant regarding weight, length, thoracic circumference and apgar score in the first and fifth minutes. conclusions: the different patterns of chorioamnionitis were related to different maternal and fetal clinical features, affecting the life conditions of the newborn and the severity of morphological lesions found in stillbirths.
O peso do ba?o em chagásicos cr?nicos
Pereira, Sanívia Aparecida de Lima;Corrêa, Beatriz Soares;Minicucci, Gisela Paludeto;Lopes, Glauce Marlei Aires;Castro, Eumênia Costa da Cunha;Reis, Marlene Antnia dos;Teixeira, Vicente de Paula Antunes;
Revista da Sociedade Brasileira de Medicina Tropical , 1999, DOI: 10.1590/S0037-86821999000200008
Abstract: during the course of systemic inflammatory reactions and chronic venous congestion, the documented phenomenon of increased spleen size is respectively called reactional hyperplasia and congestive splenomegaly. in chagas' disease, the inflammatory process observed in the heart of chronically infected patients can result in heart failure and ultimately in congestive failure. in order to evaluate the spleen response to both inflammatory and cardiac processes, in this retrospective study we compare the weight of spleens from normal and chagasic patients, with or without congestive failure. information about patient age, sex, race and spleen weight was collected from autopsy reports. eighty-eight selected cases were divided into four groups: 1) chagasic patients with congestive failure, 2) chagasic patients without congestive failure, 3) non-chagasic patients with congestive failure, 4) non-chagasic patients without congestive failure. the average age was 44.9 ± 15.4 years, 53.4% were caucasians and 70.5% were males, and no significant difference in these parameters was observed between the four groups. the spleen weight for the groups presenting congestive failure was 183.7 ± 85.9g for chagasic and 206.3 ± 101.0g for non-chagasic patients; for the groups without congestive failure the average spleen weight was 173.7 ± 118.9g for the chagasic and 117.2 ± 52.0g for non-chagasic patients. the spleen weight was significantly higher for the chagasic patients without congestive failure when compared to the non-chagasic group without congestive failure. these results suggest that the inflammatory component in chagas' disease plays an important role in the increase of spleen weight together with hemodynamic alterations arising from congestive heart failure.
Vilosite placentária e sua rela??o com intercorrências fetais e maternas
Castro, Eumenia Costa da Cunha;Salge, Ana Karina Marques;Galdino, Fabiana Jorge Bueno;Ferraz, Mara Lúcia Fonseca;Reis, Marlene Antnia dos;Corrêa, Rosana Rosa Miranda;Teixeira, Vicente de Paula Antunes;
Revista Brasileira de Ginecologia e Obstetrícia , 2004, DOI: 10.1590/S0100-72032004001000008
Abstract: purpose: placental villitis has been correlated with perinatal infection, although a percentage of cases remains etiologically unknown. the present study was aimed at the systematic morphological study of placentas for imunohistochemical characterization of villitis and assessment of its possible correlation with maternal and fetal outcome. methods: a hundred and twenty-eight placentas were studied. gross examination was performed and all collected fragments were analyzed microscopically by the hematoxylin-eosin method. villits was classified according to the inflammatory degree in to mild, moderate and severe. the immunohistochemical study to identify infectious agents was performed using monoclonal antibodies against toxoplasma gondii and cytomegalovirus. for inflammatory cell phenotype identification monoclonal antibodies against cd68, cd57, cd3, and cd20 were used. statistical analysis was performed with the variables: maternal age and fetal gestational age, fetal and placental weight, and fetal and maternal outcomes. to compare the two groups we used the mann-whitney test and for proportions we used the c2 test. the differences in the mean values between the treatment groups were considered statistically significant when p<0.05 (5%). results: villitis was identified in 11.7% of the cases. in 40% of the cases the children were stillborn (p=0.003). one case showed positive staining for toxoplasmosis while the remaining cases were negative. imunohistochemical staining showed cd68+ cells, pant+ cells and negative cd57 and panb cells. conclusion: we concluded that the intensity of the inflammatory process in the placenta was correlated with the severity of the fetal disease. the inflammatory cells in the villitis focus were macrophages; however, we could not identify infectious agents correlated with the villitis.
Altera??es anatomopatológicas da placenta e varia??es do índice de Apgar
Corrêa, Rosana Rosa Miranda;Salge, Ana Karina Marques;Ribeiro, Gustavo Augusto;Ferraz, Mara Lúcia Fonseca;Reis, Marlene Antnia dos;Castro, Eumenia Costa da Cunha;Teixeira, Vicente de Paula Antunes;
Revista Brasileira de Saúde Materno Infantil , 2006, DOI: 10.1590/S1519-38292006000200012
Abstract: objectives: to describe possible placental anatomopathological alterations associated to fetal hypoxia as evaluated by the apgar score. methods: one hundred sixty seven placentas of children delivered at the hospital escola da universidade federal do triangulo mineiro, uberaba city were analyzed both macro and microscopically; their clinical records were reviewed as well. apgar scores below 7 were considered consistent with fetal hypoxia. results: placental alterations compatible with inflammatory infiltrate and arterial hypertension were found. the latter was more often diagnosed in fetuses with 5 minutes apgar scores below 7 (p=0.017). conclusions: there may be a relationship between placental alterations and fetal hypoxia as diagnosed by the apgar score. therefore, the exam of the placenta by the pathologist could be a mean to elucidate a plausible cause of clinically undetected perinatal hypoxia.
Altera es anatomopatológicas renais em indivíduos com a síndrome da imunodeficiência adquirida
Laguna-Torres Victor Alberto,Reis Marlene Antnia dos,Menegaz Renato Augusto,Pelá Giovana Auad
Revista da Sociedade Brasileira de Medicina Tropical , 1998,
Abstract: As altera es anatomopatológicas renais foram estudadas em 119 casos de indivíduos com a síndrome da imunodeficiência humana adquirida (SIDA) no Hospital Escola da Faculdade de Medicina do Triangulo Mineiro, Uberaba MG. A partir das amostras de rim fixadas em formol, foram confeccionadas laminas e analisadas ao microscópio de luz. Dos 119 casos estudados, 67 tiveram diagnóstico de nefrite túbulo intersticial (NTI), sendo 18 inespecíficas, 2 xantogranulomatosas e encontrou-se agente infeccioso em 48: fungos em 28 (16 Cryptococcus sp, 9 Histoplasma sp, 1 Candida sp e 2 Paracoccidioides brasiliensis); bactérias em 18 (9 Mycobacterium sp); vírus em 6, Citomegalovírus. Em 43 havia necrose tubular aguda (NTA). Outros diagnósticos foram: nefrocalcinose (15,1%) e hialinose arteriolar (22,7%). Encontrou-se também 2 casos com glomeruloesclerose segmentar focal (GESF) e um caso de hiperplasia mesangial difusa. Houve predomínio da NTI, que pode ser devido às infec es oportunistas, predominando as fúngicas; a toxicidade por drogas ou ainda devido a possível a o direta do próprio vírus. A necrose tubular aguda (NTA), foi a segunda causa em freqüência, de acometimento renal da amostra. Concluiu-se que o envolvimento renal nos pacientes com SIDA apresenta um espectro variado de processos patológicos, principalmente relacionados com infec es oportunistas, o tratamento e os procedimentos para diagnósticos, e ainda as nefropatias associadas ao vírus da imunodeficiência humana (VIH).
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