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Search Results: 1 - 10 of 169430 matches for " Mariangela E. Alencar; "
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Paracoccidioidomicose: freqüência, morfologia e patogênese de les?es tegumentares
Marques, Silvio Alencar;Cortez, Daniela Barros;Lastória, Joel Carlos;Camargo, Rosangela M. Pires de;Marques, Mariangela E. Alencar;
Anais Brasileiros de Dermatologia , 2007, DOI: 10.1590/S0365-05962007000500003
Abstract: background: paracoccidioidomycosis is a highly prevalent systemic mycosis in brazil. the oral and cutaneous lesions are useful for diagnostic proposals and clinical follow-up. objective: to quantify and qualify skin lesions associated to active paracoccidioidomycosis and to correlate them with the clinical form and severity of cases. methods: an observational clinical study of cases was performed. patients were classified according to the clinical form, topographic distribution and morphology of skin lesions. results: a total of 152 patients classified as chronic form (adult type) (87.5%) or acute-subacute form (juvenile type) (12.5%) were studied. skin lesion was diagnosed in 61.2% of patients. there was no statistical correlation between presence of skin lesion and clinical form (p=1.000), nor between skin lesion and severity of disease (p=0.5607). there was statistical correlation between mucosal lesion and adult patients (p <0.001). the lesions were on the cephalic segment (47.6%), trunk (14.9%), upper limbs (14.9%), lower limbs (21.7%) and genital region (0.7%). the ulcerated lesions (42.8%) and infiltrative (26.6%) lesions prevailed. conclusion: the frequency of skin lesions and their morphology are useful for diagnosis of paracoccidioidomycosis. oral lesions in the acute-subacute form (juvenile type) are not common.
Caso para diagnóstico
Marques, Silvio Alencar;Camargo, Rosangela M. Pires de;Marques, Mariangela E. A.;
Anais Brasileiros de Dermatologia , 2007, DOI: 10.1590/S0365-05962007000600013
Abstract: paracoccidioidomycosis is a potentially severe disease that may lead to death. specific skin lesions are common and suitable for early diagnosis. dissemination to the reticuloendothelial system is the main characteristic of the acute and subacute clinical forms. pleural exudate and ascitis are rare in paracoccidioidomycosis. in the present case, these followed an acute hemorrhagic pancreatitis. amphotericin b and proper hospital care are crucial for the recovery of severe cases.
Leishmaniose cutanea acidental
Dillon, Neuza Lima;Stolf, Hamilton Ometto;Yoshida, Elizaide L. Alvarenga;Marques, Mariangela E. Alencar;
Revista do Instituto de Medicina Tropical de S?o Paulo , 1993, DOI: 10.1590/S0036-46651993000400015
Abstract: the authors report the 3rd case of cutaneous leishmaniasis due to accidental contamination of a student of biological sciences during laboratory research. the inoculation ocurred when amastigotes of leishmania (viannia) braziliensis from infected hamsters were injected in healthy animals. at this stage, the student had her glove bitten by a healthy hamster and the infection was probably conveyed by the direct contact of the inoculum with the skin.
Pythium insidiosum: relato do primeiro caso de infec??o humana no Brasil
Marques, Silvio Alencar;Bagagli, Eduardo;Bosco, Sandra M. G.;Camargo, Rosangela M. P.;Marques, Mariangela E. A.;
Anais Brasileiros de Dermatologia , 2006, DOI: 10.1590/S0365-05962006000500012
Abstract: pythiosis is caused by an aquatic fungus-like organism, pythium insidiosum, pathogenic to men and animals. a patient with a phagedenic ulcer on the leg is reported. histopathological examination was suggestive of zygomycosis, response to antifungal drugs was poor and cure was obtained by means of wide surgical excision. etiologic diagnosis was confirmed by molecular amplification and dna sequencing of colonies isolated in sabouraud agar. after blast analysis, the sequence showed 100% identity with those of p. insidiosum deposited on the genbank.
Avalia??o da gordura orbitária de coelhos após enuclea??o e eviscera??o
Shiratori, Claudia Akemi;Schellin, Silvana Artioli;Marques, Mariangela E. Alencar;Padovani, Carlos Roberto;Padovani, Carlos Roberto Pereira;
Arquivos Brasileiros de Oftalmologia , 2005, DOI: 10.1590/S0004-27492005000500011
Abstract: purpose: to evaluate rabbit adipocytes of the orbital fat tissue after enucleation and evisceration. methods: twenty-tree specimens from 23 rabbits aged 42 days which had undergone socket surgery (evisceration and enucleation) were evaluated. the animals were sacrificed on the 30th, 90th and 180th postoperative day. the orbital fat tissue was prepared for light microscope evaluation (magnification: 200x) and analyzed by ipwin 32 software program. the number of cells in each field and the area of each adipocyte were used to calculate the cell median area. the data were compared between the groups (enucleation and evisceration) and submitted to statistical analysis by a non-parametrical test. results: there were no statistical differences when considering the mean area of adipocytes between enucleation or evisceration or time of sacrifice. conclusion: the volume decrease in the anophthalmic cavity is not related to orbital fat atrophy. the genesis of orbital volume reduction might result from the spacial distribution and interrelationships of the orbital soft tissue rather than changes in volume of adipocytes.
Tratamento da úlcera corneana experimental com membrana amniótica
Monteiro, Eliana Cristina Louza;Schellini, Silvana Artioli;Marques, Mariangela E. Alencar;Kamegasawa, Amélia;Padovani, Carlos Roberto;
Arquivos Brasileiros de Oftalmologia , 2000, DOI: 10.1590/S0004-27492000000100007
Abstract: purpose: to evaluate healing of experimental corneal ulcer of rabbit eyes terated with homologous amniotic membrane (am) graft. methods: 18 rabbits were used and divided into two experimental groups: corneal ulcer (g1) and corneal ulcer treated with am graft (g2). corneal ulcer was induced by a total epithelial removal using a scalpel and absolute alcohol. the animals were sacrificed at three experimental moments: 7 days (m1), 15 days (m2) and 30 days (m3) after the induction of the ulceration. corneal defects were evaluated with image analyzer luzex-f and histopathologic examinations and the results were compared through variance analysis. results: morphometric results showed corneal ulcer in g2 at m1; corneal opacity was identified in the central area and was significantly larger in g1 at m3. new corneal vessels were more active in the g1 animals. histopathologic evaluation revealed epithelial defects in two animals of g1 at m2, and in two of g2 at m1; stromal edema was more intense in g1, as well as the presence of new vessels. conclusion: the use of homologous ma in the treatment of experimental corneal ulcer did not accelerate epithelial healing but it prevented stromal edema and new vessel formation. epithelial healing was poorer in the central region of the cornea.
Surto de leishmaniose tegumentar americana em Itaporanga, S?o Paulo (Brasil)
Stolf, Hamilton Ometto;Marques, Silvio Alencar;Marques, Mariangela E. A.;Yoshida, Elizaide L. A.;Dillon, Neuza Lima;
Revista do Instituto de Medicina Tropical de S?o Paulo , 1993, DOI: 10.1590/S0036-46651993000500009
Abstract: an outbreak of cutaneous leishmaniasis in a small rural settlement, located in the southern of s?o paulo state - brazil was observed. this region has basic agricultural activities, and has no forests. two hundred and thirty one persons were evaluated, and the following aspects were observed: 1) 67 individuals (29%) had skin lesions, confirmed by histopathologic study and the montenegro skin test; 2) of these cases, 40 (59.7%) were males; 3) the youngest patients were 2 years (5 cases), and the oldest, 86 (1 case); 4) the following types of cutaneous lesions, were observed: a) 54 cases (80.6%) had ulcers, 13 (19.4%) had nodules, 4 (5.9%) had verrucose lesions, and 3 (4.4%) had typical scars. in all the cases, the parasite identified was leishmania (viannia) braziliensis. the vector captured in the region was lutzomyia intermedia, a strong anthropophilic sandfly very frequently observed in s?o paulo. this study shows that apart from the well-known outbreak observed in the forest environments, leishmaniasis can be transmitted within or around dwellings.
Prevalence of precancerous skin lesions and non-melanoma skin cancer in Japanese-Brazilians in Bauru, S?o Paulo State, Brazil
Ishioka, Priscila;Marques, Sílvio Alencar;Hirai, Amélia Toyomi;Marques, Mariangela E. A.;Hirata, Sérgio Henrique;Yamada, Sérgio;
Cadernos de Saúde Pública , 2009, DOI: 10.1590/S0102-311X2009000500003
Abstract: precancerous lesions and skin cancer are infrequent in asians, and have received little documentation in the literature. brazil has the world's largest contingent of japanese immigrants and their descendants, and 70% live in the state of s?o paulo. the prevalence of such skin lesions in japanese-brazilians is unknown. this study aimed to assess the prevalence of actinic keratoses and non-melanoma skin cancer in first and second-generation japanese-brazilians over 30 years of age, without miscegenation, living in the city of bauru, s?o paulo state, in 2006. of the 567 japanese-brazilians that underwent dermatological examination, actinic keratosis was diagnosed in 76, with a mean age of 68.9 years, and a single case of basal cell carcinoma was detected in a 39-year-old female patient. in japan, prevalence of actinic keratosis varies from 0.76% to 5%, and the incidence of non-melanoma skin cancer is 1.2 to 5.4/100 thousand. japanese-brazilians from bauru showed a 13.4% prevalence of actinic keratoses and earlier age at onset. proximity to the equator and a history of farming contribute to these higher rates. presence of solar melanosis was associated with a 1.9-fold risk of developing actinic keratosis.
Paracoccidioidomycosis: infiltrated, sarcoid-like cutaneous lesions misinterpreted as tuberculoid leprosy
Marques, Sílvio Alencar;Lastória, Joel Carlos;Putinatti, Maria Stella de M.A.;Camargo, Rosangela Maria Pires de;Marques, Mariangela E. A.;
Revista do Instituto de Medicina Tropical de S?o Paulo , 2008, DOI: 10.1590/S0036-46652008000100010
Abstract: the authors report a case of paracoccidioidomycosis misinterpreted as tuberculoid leprosy, both on clinical and histological examination. sarcoid-like cutaneous lesion as the initial presentation is rare in young patient with paracoccidioidomycosis and can simulate other infectious or inflammatory diseases. on histology, tuberculoid granuloma presented similar difficulties. treatment with dapsone, a sulfonamide derivative, could have delayed the presumed natural clinical course to the classical juvenile type of paracoccidioidomycosis, observed only 24 months after the patient had been treated for leprosy.
Critérios anatomopatológicos para melanoma maligno cutaneo: análise qualitativa de sua eficácia e revis?o da literatura
Veronese, Luiz Alberto;Marques, Mariangela Esther Alencar;
Jornal Brasileiro de Patologia e Medicina Laboratorial , 2004, DOI: 10.1590/S1676-24442004000200009
Abstract: the challenge and the diagnostic difficulty imposed by some melanocytic lesions are well known by the pathologists. the lack of uniform diagnostic criteria is, without a doubt, one of the main causes for the high rates of disagreement described in literature. the aim of this report is to review twelve selected criteria in order to reduce diagnostic disagreement. these are: 1) size; 2) symmetry; 3) lateral delimitation; 4) maturation; 5) pagetoid spreading; 6) necrosis/ulceration; 7) inflammatory reaction; 8) regression; 9) cellular atypias; 10) mitosis; 11) melanization; 12) isolated cells proliferation. the characteristics of each one and their application in the diagnosis of melanomas were shown, always remembering possible exceptions in which these criteria might present in benign melanocytic lesions. farther more, tables of differential diagnostic features are offered, for benign and malignant melanocytic lesions, using these histopathological criteria. as any criterion must not be considered by itself, the rigorous application of this data set here provided can substantially help the generalist surgical pathologist (non-specialist in melanocytic lesions) to solve some of the problems at his daily routine.
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