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Search Results: 1 - 10 of 230757 matches for " Mariana da Cunha Lopes de;Santos "
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Estimation of absolute renal uptake with technetium-99m dimercaptosuccinic acid: direct comparison with the radioactivity of nephrectomy specimens
Lima, Mariana da Cunha Lopes de;Ramos, Celso Darío;Brunetto, Sérgio Quirino;Lima, Marcelo Lopes de;Ferreira, Ubirajara;Etchebehere, Elba Cristina Sá Camargo;Santos, Allan de Oliveira;Netto Júnior, Nelson Rodrigues;Camargo, Edwaldo Eduardo;
Sao Paulo Medical Journal , 2008, DOI: 10.1590/S1516-31802008000300003
Abstract: context and objective: studies using radionuclides are the most appropriate method for estimating renal function. dimercaptosuccinic acid chelate labeled with technetium-99m (99mtc-dmsa) is the radiopharmaceutical of choice for high-resolution imaging of the renal cortex and estimation of the functional renal mass. the aim of this study was to evaluate a simplified method for determining the absolute renal uptake (aru) of 99mtc-dmsa prior to nephrectomy, using the radioactivity counts of nephrectomy specimens as the gold standard. design and setting: prospective study at the division of nuclear medicine, department of radiology, universidade estadual de campinas. methods: seventeen patients (12 females; range 22-82 years old; mean age 50.8 years old) underwent nephrectomy for various reasons. renal scintigraphy was performed three to four hours after intravenous administration of a mean dose of 188.7 mbq (5.1 mci) of 99mtc-dmsa, which was done six to 24 hours before surgery. the in vivo renal uptake of 99mtc-dmsa was determined using the radioactivity of the syringe before the injection (measured using a dose calibrator) and the images of the syringe and kidneys, obtained from a scintillation camera. after surgery, the reference value for renal uptake of 99mtc-dmsa was determined by measuring the radioactivity of the nephrectomy specimen using the same dose calibrator. results: the aru measurements were very similar to those obtained using the reference method, as determined by linear regression (r-squared = 0.96). conclusion: aru estimation using the proposed method before nephrectomy seems to be accurate and feasible for routine use.
Functional electrical stimulation improves brain perfusion in cranial trauma patients
Amorim, Bárbara Juarez;Santos, Allan de Oliveira;Oberg, Telma Dagmar;Romanato, Juliana;Anjos, Dalton A.;Lima, Mariana da Cunha Lopes de;Ramos, Celso Darío;Honorato, Donizete Cesar;Camargo, Edwaldo Eduardo;Etchebehere, Elba Cristina de Sá Camargo;
Arquivos de Neuro-Psiquiatria , 2011, DOI: 10.1590/S0004-282X2011000500020
Abstract: objective: demonstrate brain perfusion changes due to neuronal activation after functional electrical stimulation (fes). method: it was studied 14 patients with hemiplegia who were submitted to a program with fes during fourteen weeks. brain perfusion spect was performed before and after fes therapy. these patients were further separated into 2 groups according to the hemiplegia cause: cranial trauma and major vascular insults. all spect images were analyzed using spm. results: there was a significant statistical difference between the two groups related to patient's ages and extent of hypoperfusion in the spect. patients with cranial trauma had a reduction in the hypoperfused area and patients with major vascular insult had an increase in the hypoperfused area after fes therapy. conclusion: fes therapy can result in brain perfusion improvement in patients with brain lesions due to cranial trauma but probably not in patients with major vascular insults with large infarct area.
Low sensitivity of three-phase bone scintigraphy for the diagnosis of repetitive strain injury
Amorim, Bárbara Juarez;Etchebehere, Elba Cristina Sá de Camargo;Torre, Graciella Dalla;Lima, Mariana da Cunha Lopes de;Santos, Allan de Oliveira;Ramos, Celso Darío;Gonzalez, Luiz Ricardo;Oliveira, José Inácio;Camargo, Edwaldo Eduardo;
Sao Paulo Medical Journal , 2006, DOI: 10.1590/S1516-31802006000300007
Abstract: context and objective: the diagnosis of repetitive strain injury (rsi) is subjective and solely based on clinical signs and physical examination. the aim of this paper was to assess the usefulness of three-phase bone scintigraphy (tpbs) in diagnosing rsi. design and setting: prospective study at the division of nuclear medicine, department of radiology, school of medical sciences, universidade estadual de campinas (unicamp). methods: seventy-three patients (mean age 31.2 years; 47 males) with clinical suspicion of rsi in the upper limbs were studied. a total of 127 joints with suspicion of rsi were studied. the shoulders, elbows and wrists were analyzed semi-quantitatively, using the shafts of the humeri and ulnae as references. the results were compared with a control group of 40 normal individuals. the patients? signs and symptoms were used as the "gold standard" for calculating the probabilities. results: from visual analysis, abnormalities were observed in the flow phase for four joints, in the blood pool phase for 11 joints and in the delayed images for 26 joints. visual analysis of the joints of the control group did not show any abnormalities. semi-quantitative analysis showed that most of the patients? joint ratios were normal. the exceptions were the wrists of patients with left-sided rsi (p = 0.0216). however, the sensitivity (9%) and accuracy (41%) were very low. conclusion: tpbs with semi-quantitative analysis has very low sensitivity and accuracy in the detection of rsi abnormalities in the upper limbs.
Brain SPECT in mesial temporal lobe epilepsy: comparison between visual analysis and SPM
Amorim, Bárbara Juarez;Ramos, Celso Darío;Santos, Allan Oliveira dos;Lima, Mariana da Cunha Lopes de;Min, Li Li;Camargo, Edwaldo Eduardo;Cendes, Fernando;Etchebehere, Elba Cristina Sá de Camargo;
Arquivos de Neuro-Psiquiatria , 2010, DOI: 10.1590/S0004-282X2010000200001
Abstract: objective: to compare the accuracy of spm and visual analysis of brain spect in patients with mesial temporal lobe epilepsy (mtle). method: interictal and ictal spects of 22 patients with mtle were performed. visual analysis were performed in interictal (visual(inter)) and ictal (visual(ictal/inter)) studies. spm analysis consisted of comparing interictal (spm(inter)) and ictal spects (spm(ictal)) of each patient to control group and by comparing perfusion of temporal lobes in ictal and interictal studies among themselves (spm(ictal/inter)). results: for detection of the epileptogenic focus, the sensitivities were as follows: visual(inter)=68%; visual(ictal/inter)=100%; spm(inter)=45%; spm(ictal)=64% and spm(ictal/inter)=77%. spm was able to detect more areas of hyperperfusion and hypoperfusion. conclusion: spm did not improve the sensitivity to detect epileptogenic focus. however, spm detected different regions of hypoperfusion and hyperperfusion and is therefore a helpful tool for better understand pathophysiology of seizures in mtle.
Fatores associados ao padr?o de sono em pacientes com insuficiência cardíaca
Santos, Mariana Alvina dos;Cruz, Diná de Almeida Lopes Monteiro da;Barbosa, Ricardo Luís;
Revista da Escola de Enfermagem da USP , 2011, DOI: 10.1590/S0080-62342011000500011
Abstract: the objective of this study was to describe sleep patterns in patients with heart failure (hf) and analyze associations between sleep and the following variables: gender, age, fatigue, fatigue on exertion, physical activity, functional class, drug therapy, dyspnea, and body mass index. the nonprobability sample consisted of 400 patients (mean age 57.8 years; 64.8% were men, average schooling of 6.1 years; 82.5% functional class ii or iii). the prevalence of poor sleepers was 68.5%, and 46.5% rated sleep as poor or very poor. scores suggest that the bad sleeper category was associated with: female, unemployed, fatigue, fatigue on exertion, dyspnea and higher functional classes of hf. the proportion of poor sleepers among patients with hf is among the highest in chronic diseases. dyspnea and fatigue, common symptoms of this disease, significantly increase the chance of being a bad sleeper.
Diagnóstico da tuberculose em indígenas menores de quinze anos por meio de um sistema de pontua o em Mato Grosso do Sul Scoring system for the diagnosis of tuberculosis in indigenous children and adolescents under 15 years of age in the state of Mato Grosso do Sul, Brazil
Sandra Christo dos Santos,Ana Maria Campos Marques,Roselene Lopes de Oliveira,Rivaldo Venancio da Cunha
Jornal Brasileiro de Pneumologia , 2013,
Abstract: OBJETIVO: Avaliar o processo diagnóstico da tuberculose pulmonar em indígenas menores de 15 anos, por meio do Sistema de Pontua o do Ministério da Saúde Modificado (SP-MSm), em crian as e adolescentes com resultados negativos na baciloscopia. MéTODOS: Estudo descritivo retrospectivo de 49 casos de tuberculose em indígenas menores de 15 anos no estado do Mato Grosso do Sul entre 2007 e 2010. RESULTADOS: Dos 49 pacientes, 27 (56%) eram menores de 5 anos, 33 (67%) apresentavam sintomas sugestivos de tuberculose, 24 (49%) tinham baixo peso, e 36 (73,5%) haviam sido vacinados com BCG. O teste tuberculínico foi reator em 28 pacientes (57%). Dentre esses, 18 (64%) apresentaram endura o > 10 mm. Foram realizadas radiografias de tórax em 37 pacientes (76%), sendo que 31 (84%) fizeram apenas um exame. Desses 37 pacientes, os achados radiológicos eram sugestivos de tuberculose em 16 (43%), de infiltrado/condensa o em 10 (27%) e normais em 4 (11%). As Equipes de Saúde Indígena foram responsáveis pelo diagnóstico em 31 (63%) dos casos, mas o SP-MS original só foi utilizado em 14 (45%). Os escores do SP-MSm foram determinados em 30 pacientes (61%). Dos 30 casos pontuados, os resultados dos escores indicaram diagnóstico de tuberculose muito provável, possível e pouco provável em 16 (53%), 11 (37%) e 3 (10%), respectivamente. CONCLUS ES: A propor o de diagnóstico muito provável e possível foi concordante com o diagnóstico padr o do servi o (90%), evidenciando a aplicabilidade epidemiológica do SP-MSm para o diagnóstico da tuberculose pulmonar em indígenas, de forma compatível com a realidade do servi o de saúde prestado. OBJECTIVE: To evaluate the process of diagnosing pulmonary tuberculosis in smear-negative indigenous children and adolescents under 15 years of age with the modified Brazilian National Ministry of Health Scoring System (mBNMH-SS). METHODS: This was a retrospective descriptive study involving 49 indigenous patients under 15 years of age with tuberculosis, treated between 2007 and 2010 in the state of Mato Grosso do Sul, Brazil. RESULTS: Of the 49 patients, 27 (56%) were under 5 years of age, 33 (67%) had symptoms suggestive of tuberculosis, 24 (49%) were underweight, and 36 (73.5%) had been BCG vaccinated. The tuberculin skin test was positive in 28 patients (57%), 18 (64%) of whom had an induration > 10 mm. Chest X-rays were performed in 37 (76%) of the patients, 31 (84%) of whom had only one chest X-ray taken. Among those 37 patients, the radiological findings were suggestive of tuberculosis in 16 (43%), infiltration/condensation in 10 (27%), and
-DTPA Study to Validate an Experimental Model of Ureteral Obstruction in Rabbits: Preliminary Results
Marcelo Lopes de Lima,Rodolfo Bertti,Juliano César Moro,Fábio Coltro Neto,Ricardo Miyaoka,Adriano Fregonesi,Mariana da Cunha Lopes de Lima,Celso Darío Ramos
Advances in Urology , 2013, DOI: 10.1155/2013/929620
Abstract: Objective. To create a ureteral obstruction experimental model that can be proved through -DTPA renal scintigraphy and histopathological studies, without causing total renal function loss. Materials and Methods. Ten New Zealand white rabbits were submitted to a surgical experiment to create a model of unilateral obstruction to urinary flow. Surgery procedure provided unilateral ureteral obstruction (left kidney) to urinary flow and posteriorly was evaluated by -DTPA renal scintigraphy and histopathological study. -DTPA renal study was performed to detect and quantify signs of obstruction and to evaluate renal function. Statistical analysis was performed through the Student -test with a significance level of . Results. Nine of the ten rabbits presented left renal unit obstruction and one nonobstructive on the -DTPA and histopathological studies. All the right renal units, which were not submitted to surgical procedure, were nonobstructed by the studies. There was a general agreement between scintigraphy and histopathological results in both groups. Conclusion. The experimental model promoted the creation of ureteral obstruction in rabbits, confirmed by nuclear medicine scintigraphy and histopathology, and could be used in further studies to better understand urinary obstruction. 1. Introduction Pelvi-ureteric junction (PUJ) obstruction is one of the most frequent congenital anomalies of the urinary tract system. It is associated with pain, hydronephrosis, urinary tract infections, and eventually loss of renal function [1, 2]. It affects around 40% to 60% of all newborns with hydronephrosis [3], two times more common in males, and may be bilateral in 5% to 15% of cases [1, 4]. PUJ obstruction may be caused by intrinsic factors, like aperistaltic ureteral segment, obstructive fold mucosa, ureteral polyp, or ureteral stenosis [5]. Among extrinsic factors stands inferior renal polar vessel crossing anteriorly the PUJ [6]. Treatment varies from clinical observation to surgery. There are some surgical modalities available to correct the PUJ obstruction, differing from the open pyeloplasty to the latest in technology such as robotic assisted surgeries and endourological procedures [7–9]. Currently scientific literature is short in ureteral obstruction models that accurately reproduce the clinical and microscopic features of this infirmity [10–12]. The creation of a standardized experimental model that would be able to cause obstructive disturbance without leading to renal function loss would provide information capable of enhancing not only the diagnosis but
Gallium-67 imaging in a patient with paracoccidioidomycosis: a case report
TEIXEIRA Ana Beatriz Marinho de Jesus,ETCHEBEHERE Elba Cristina Sá de Camargo,LIMA Mariana Cunha Lopes de,SANTOS Allan de Oliveira
Revista do Instituto de Medicina Tropical de S?o Paulo , 2000,
Abstract: A 26 year-old female was admitted with abdominal pain, fever and weight loss. The clinical and laboratory investigations led to the diagnosis of paracoccidioidomycosis. Gallium-67 whole body images correlated well with the clinical course of the disease and with the patient's prognosis.
A TRANSPARêNCIA DA INFORMA O POR PARTE DOS EMITENTES TRANSPARENCY OF INFORMATION ON THE PART OF EMITTERS
Helena Maria Santos de Oliveira,Cláudia Maria Ferreira Pereira Lopes,Carlos Alberto da Silva e Cunha
Revista Universo Contábil , 2008,
Abstract: Neste trabalho, efectuamos uma revis o de literatura sobre a relevancia da transparência da informa o financeira por parte dos emitentes de valores mobiliários admitidos à negocia o em mercados regulamentados que se situem nos Estados membros da Uni o Europeia. Desta resulta consensual que a transparência nas demonstra es financeiras (DF) é uma quest o cada vez mais fundamental dada a forte internacionaliza o das empresas e globaliza o dos mercados, afectando o fluxo de capitais e o próprio desenvolvimento dos mercados financeiros. A Directiva 2004/109/CE do Parlamento Europeu e do Conselho, de 15 de dezembro de 2004, reflecte a preocupa o dos Estados membros em harmonizar os requisitos e critérios de transparência, particularmente no seguimento da Directiva 2003/34/CE, sobre os Prospectos, no que se refere às informa es respeitantes aos emitentes de valores mobiliários. Esta quest o da transparência foi também muito impulsionada pela promulga o da Sarbanes-Oxley Act. In this work, we review some of the literature that deals with the relevance of the transparency of financial information disclosed by firms whose stock is traded on regulated financial markets located in the European Union. From this review it is agreed that the transparency of financial reports is becoming an increasingly important question since the internationalization of firms and globalization of markets are becoming stronger. These situations affect capital flow and the development of financial markets. Directive 2004/109/CE of the European Parliament and Council, issue on 15th December 2004, shows the preoccupation of European Members about the use the of criteria for transparency, namely in following the 2003/34/CE Directive, related with the Prospectus, in the case of firms that have issued stock. The importance of transparency also increases with the Sarbanes-Oxley Act.
Gallium-67 imaging in a patient with paracoccidioidomycosis: a case report
TEIXEIRA, Ana Beatriz Marinho de Jesus;ETCHEBEHERE, Elba Cristina Sá de Camargo;LIMA, Mariana Cunha Lopes de;SANTOS, Allan de Oliveira;PIRES, Bruno Cunha;VALEN?A JR., José Telmo;RAMOS, Celso Darío;CAMARGO, Edwaldo E.;
Revista do Instituto de Medicina Tropical de S?o Paulo , 2000, DOI: 10.1590/S0036-46652000000300011
Abstract: a 26 year-old female was admitted with abdominal pain, fever and weight loss. the clinical and laboratory investigations led to the diagnosis of paracoccidioidomycosis. gallium-67 whole body images correlated well with the clinical course of the disease and with the patient's prognosis.
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