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Search Results: 1 - 10 of 38526 matches for " Mariana Sant’Anna Pereira Nicolau "
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Expression Analysis of Two Genes Coding for Trehalose-6-Phosphate Synthase (TPS), in Sugarcane (Saccharum spp.) under Water Stress  [PDF]
Nilson Nicolau Junior, Mariana SantAnna Pereira Nicolau, Luana Jandhy Mantovanini, Sonia Marli Zingaretti
American Journal of Plant Sciences (AJPS) , 2013, DOI: 10.4236/ajps.2013.412A3011
Abstract:

The accumulation of trehalose (α-D-glucopyranosyl-[1,1]-α-D-glucopyranoside), a sugar with osmoprotectant properties, is very common in microorganisms, invertebrates and in resurrection plants. However, in the majority of higher plants, it is found in trace amounts. Trehalose is synthesized from the UDP-glucose and glucose-6-phosphate in a two-step process with two enzymes, trehalose-6-phosphate synthase or TPS (EC 2.4.1.15 and EC 2.4.1.36) and trehalose-6-phosphate phosphatase or TPP (EC 3.1.3.12). The trehalose-6-phosphate synthase and its product of the trehalose-6-phosphate (T6P) are probable signaling molecules in the carbohydrate metabolism, contributing to enhancing the plants tolerance to water stress. Water scarcity is one of the most important factors that influence productivity in sugarcane (Saccharum spp.) and it activates a cascade of metabolic events and necessary morphologic changes for the survival of the plant under stress. Here we show the in silico expression study of TPS in different libraries from the SUCEST project. Our results showed that the TPS genes are present in all tissues and that they are divided into two subfamilies (class I and II). It is shown that STPS1 belongs to the class I, therefore, it does not have an active phosphatase (TPP) domain, whereas, the STPS2 has an active TPP domain (class II) determined by the presence of phosphatase boxes. Expression analyses based on the semi-quantitative method of the reverse transcription polymerase chain reaction (RT-PCR) show that the STPS1 gene is up-regulated in the tolerant cultivar under stress and down-regulated in susceptible plants. The STPS2 gene does not show considerable variations in the expression levels under the same treatments. The discovery of active genes such as STPS1 and STPS2 in plants under water stress, contributes for the concerning about the cascade of responses in plants under water deficit and points out to target genes for plant breeding.

ESQUERDAS LATINO-AMERICANAS E GASTO SOCIAL: Há COERêNCIA ENTRE PROPOSTAS E PRáTICAS?
Julia Sant'Anna,Fabricio Pereira da Silva
Revista Debates , 2008,
Abstract: This paper analyses social spending of left and center-left governments recently elected in Latin American countries. It compares the expenditure on targeted social programs as well as on health and education trying to identify what the actions these so-called progressive administrations would be bringing to thesocial field with regards to old practices. It also stresses the relation between proposals presented by these progressive actors before they were in power and what the put in practice afterwards.
“Masculin Fèminin” sob as lentes de Clio
Ivonete Pereira,Mara Rúbia Sant'Anna
Espa?o Plural , 2010,
Abstract: Through analysis of the movie "MasculinFéminin", this article aims to reflect on the intricateability that cinematographic language contains initself to construct and deconstruct discourses, tounderline behavioral models, human types, subjectiveconditions of being and living. In particular, we willfocus in the gender relations, that appear in the movie,from images and dialogues cuts and discontinuousrhythms.
Analgesia pós-operatória para cesariana: a adi??o de clonidina à morfina subaracnóidea melhora a qualidade da analgesia?
Neves, José Francisco Nunes Pereira das;Monteiro, Giovani Alves;Almeida, Jo?o Rosa de;Sant'Anna, Roberto Silva;Saldanha, Rodrigo Machado;Moraes, José Mariano Soares de;Nogueira, Emerson Salim;Coutinho, Fernando Lima;Neves, Mariana Moraes Pereira das;Araújo, Fernando Paiva;Nóbrega, Paula Brazilio;
Revista Brasileira de Anestesiologia , 2006, DOI: 10.1590/S0034-70942006000400005
Abstract: background and objectives: the mechanism of action of a2-adrenergic analgesia has been explored for more than one hundred years. the increased duration of the sensitive and motor blockades caused by clonidine is dose-dependent and has antinociceptive properties. the objective of this study was to evaluate whether the addition of 15 to 30 μg of clonidine to spinal anesthesia for cesarean sections with 0.5% hyperbaric bupivacaine (12.5 mg) and morphine (100 μg) improves the quality of postoperative analgesia. methods: we realized a prospective, randomized study that included 60 patients divided in 3 groups: bm - 0.5% hyperbaric bupivacaine (12.5 mg) and morphine (100 μg), bm15 - 0.5% hyperbaric bupivacaine (12.5 mg), morphine (100 μg), and clonidine (15 mg), and bm30 - 0.5% hyperbaric bupivacaine (12.5 mg), morphine (100 μg), and clonidine (30 μg), administered separately. in the perioperative period the use of ephedrine and the newborn's apgar score were recorded. in the postoperative period, the pain was evaluated in the 12th h by the vas, the length of time it took the patient to ask for analgesics, and the postoperative side effects, such as pruritus, nausea, vomiting, bradycardia, hypotension, and sedation. the values were considered significant when p < 0.05. results: the groups were homogenous. the use of ephedrine and the evaluation by the apgar score did not show statistically significant differences among the different groups. the pain scores and the average time to start analgesia showed differences among the groups bm and bm15/bm30, and there were no differences regarding the incidence of postoperative side effects. conclusions: the addition of clonidine to spinal anesthesia with 0.5% hyperbaric bupivacaine (12.5 mg) and morphine (100 μg) for cesarean section improved the quality of the postoperative analgesia without increasing the incidence of side effects. we suggest that the dose of 15 μg of clonidine should be used.
“Fixar a onda de luz”: O problema da transi o das épocas históricas no conceito de helenismo em Johann Gustav Droysen
Pedro Spinola Pereira Caldas,Henrique Modanez de SantAnna
História da Historiografia , 2008,
Abstract: O objetivo deste artigo consiste na análise da importancia da obra de Johann Gustav Droysen sobre o período helenístico para a legitima o da historiografia e sua autonomia perante a filosofia hegeliana da história. Com o fito de compreender tal papel, será essencial discutir o conceito de transi o histórica.
CPP-TRI: UM MéTODO DE CLASSIFICA O ORDENADA BASEADO EM COMPOSI O PROBABILíSTICA
Annibal Parracho SantAnna,Helder Gomes Costa,Valdecy Pereira
Relatórios de Pesquisa em Engenharia de Produ??o , 2012,
Abstract: Prop e-se aqui um método de classifica o multicritério baseado em rela es de sobreclassifica o que prescinde completamente da atribui o de pesos aos critérios. Este método é baseado no ELECTRE-TRInC, distinguindo-se por substituir o uso de patamares de indecis o pela adi o de perturba es aleatórias para levar em conta a imprecis o nas avalia es. Assim os valores segundo cada critério, tanto para asavalia es das alternativas quanto para os perfis característicos das classes s o tratados como parametros de loca o de distribui es de probabilidades e as compara es s o realizadas entre tais distribui es. Isto permite que a credibilidade das rela es e a composi o dos critérios sejam baseadas em probabilidade conjuntas. O modelo proposto foi aplicado aos dados do caso reportado em Almeida Dias et al. (2012), sendo os resultados contrastados
Environmental health in public health community practice: An integrative review of the literature  [PDF]
Marta Regina Cezar-Vaz, Clarice Alves Bonow, Cynthia Fontella SantAnna, Laurelize Pereira Rocha, Marlise Capa Verde de Almeida, Mara Regina Santos da Silva
Health (Health) , 2013, DOI: 10.4236/health.2013.59194
Abstract:

It is understood that the performance of Public Health Nursing is indispensable for the development of sustainable health communities, with regard to sub-standard living conditions in environments that include physical, chemical and biological factors influencing these conditions. This work is in an integrative review which aims to characterize how Environmental Health appears in scientific Public Health Nursing production, for the development of community health. Out of 442 articles, 30 met the search criteria. The publications covered contamination and exposure to environmental risks; strengthening of community groups for environmental health and workforce development of public health nursing for community practice in environmental health. The results summarized in the present study support the growing trend of interest in Environmental Health as knowledge which is essential to Public Health Nursing practice in the community.

A novel method to discover fluoroquinolone antibiotic resistance (qnr) genes in fragmented nucleotide sequences
Boulund Fredrik,Johnning Anna,Pereira Mariana Buongermino,Larsson DG Joakim
BMC Genomics , 2012, DOI: 10.1186/1471-2164-13-695
Abstract: Background Broad-spectrum fluoroquinolone antibiotics are central in modern health care and are used to treat and prevent a wide range of bacterial infections. The recently discovered qnr genes provide a mechanism of resistance with the potential to rapidly spread between bacteria using horizontal gene transfer. As for many antibiotic resistance genes present in pathogens today, qnr genes are hypothesized to originate from environmental bacteria. The vast amount of data generated by shotgun metagenomics can therefore be used to explore the diversity of qnr genes in more detail. Results In this paper we describe a new method to identify qnr genes in nucleotide sequence data. We show, using cross-validation, that the method has a high statistical power of correctly classifying sequences from novel classes of qnr genes, even for fragments as short as 100 nucleotides. Based on sequences from public repositories, the method was able to identify all previously reported plasmid-mediated qnr genes. In addition, several fragments from novel putative qnr genes were identified in metagenomes. The method was also able to annotate 39 chromosomal variants of which 11 have previously not been reported in literature. Conclusions The method described in this paper significantly improves the sensitivity and specificity of identification and annotation of qnr genes in nucleotide sequence data. The predicted novel putative qnr genes in the metagenomic data support the hypothesis of a large and uncharacterized diversity within this family of resistance genes in environmental bacterial communities. An implementation of the method is freely available at http://bioinformatics.math.chalmers.se/qnr/.
Detec??o do risco para interna??o hospitalar em popula??o idosa: um estudo a partir da porta de entrada no sistema de saúde suplementar
Estrella, Kylza;Oliveira, Claudia E. F.;Sant'Anna, Anne A.;Caldas, Célia Pereira;
Cadernos de Saúde Pública , 2009, DOI: 10.1590/S0102-311X2009000300005
Abstract: population aging requires new strategies for the evaluation and care of different elderly groups. the aim of this study was to present a single entry point model for health care to the elderly in a health maintenance organization. the model prioritizes care for individuals at greatest risk, defining the groups followed subsequently under a specific program for prevention and care. telephone interviews were used to evaluate the probability of hospitalization for 2,637 users of the health plan. 53.9% of the individuals who were contacted agreed to participate in the survey, and an index was calculated to estimate the probability of hospitalization. 3.23% of subjects were classified as high risk, 7.23% as medium-high risk, and 13.4% as medium risk. subsequent prioritization of care was based on this stratification. the model will enable improved planning and definition of priorities for resource allocation within a health care system subject to serious funding limitations. studies that identify criteria for the distribution of health care resources are thus essential to the success of consistent and realistic health policies for the elderly.
Restringindo flexibilidade de pesos em DEA utilizando análise de regress?o MSEA
Alcantara, Antonio Allen Meireles;Sant'Anna, Annibal Parracho;Lins, Marcos Pereira Estellita;
Pesquisa Operacional , 2003, DOI: 10.1590/S0101-74382003000200006
Abstract: in this paper we present a procedure based on the use of minimum sum of absolute errors (msae) regression for the treatment of factor weights in data envelopment analysis (dea). it develops and presents alternative method to limit the range within which these factor weights are allowed to vary when models using a single output are analyzed.
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