Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99


Search Results: 1 - 10 of 1412 matches for " Marian Beekman "
All listed articles are free for downloading (OA Articles)
Page 1 /1412
Display every page Item
Flapteksten. Een verkennend onderzoek
Beekman, Klaus
Neerlandistiek.nl , 2007,
Evaluating a Student MIS in the Tertiary Education Sector: Addressing Functional-Operational Misalignment through Continuous Participative Evaluation  [PDF]
Marian Carcary
Journal of Service Science and Management (JSSM) , 2010, DOI: 10.4236/jssm.2010.31004
Abstract: The Information and Communications Technology (ICT) evaluation literature spans several decades. ICT evaluation approaches range from objective and positivistic to subjective and interpretive. While positivistic approaches have dominated the past, there is increasing recognition of the value of interpretivist methods and the need for ongoing project evaluation. Formative continuous participative evaluation (CPE) offers several benefits in terms of project control, enhanced stakeholder relationships and benefit realisation; nonetheless this is often ignored in practice. There is a paucity of ICT evaluation within the Higher Education sector. The 14 Irish Institutes of Technology (IoTs) recently underwent an extensive transformation of their ICT systems, through a nationwide implementation of a suite of integrated IS. This research study, centred on the evaluation of the Student MIS implementation was interpretive in nature; case studies were conducted in five IoTs. This paper focuses specifically on one issue uncovered through the research i.e. the misalignment between the Student MIS and the IoTs requirements. The paper proposes a set of guidelines for addressing this issue through focusing on the theoretical underpinnings of CPE and its importance for organisational learning and benefit realisation.
Cancer Status: Mocb and tPSA Prostate Cancer Markers  [PDF]
Marian Surma
Journal of Cancer Therapy (JCT) , 2012, DOI: 10.4236/jct.2012.36144
Abstract: On the basis of the results of magneto-optical studies and their comparison with the outcome of medical tests magneto-optical MOCB and tPSA serum markers of cancer/recovered patient are presented. Status of the cancer serum donor is recognized as presence of the laevorotatory optical active molecules of (-)p density in serum while status of the recovered donor is recognized as quantitative domination of the dextrorotatory (+)p molecules in serum. These molecular information carriers (-)p and (+)p are recorded by the magneto-optical circular birefringence MOCB effect in B2 magnetic field. The laevo/dextrorotatory carriers are enantiomers in the case of (-)p = (+)p relations fulfilled for any individual cancer and the same recovered patient. The positive predictive value PPV of MOCB results is 100%.
Enantiomers Present in Serum Carry Cancer and/or Recovery Status Information  [PDF]
Marian Surma
Journal of Cancer Therapy (JCT) , 2014, DOI: 10.4236/jct.2014.56071

Human blood serum of cancer, cancer-recovered and healthy patients contains laevorotatory and dextrorotatory B2 active molecules. The laevorotatory B2 active carriers in patient serum carry information on the cancer status while the dextrorotatory B2 active carriers carry information on the recovered and/or healthy patient status. Their magneto-optical characteristic is analysed by the B2 Magneto Optical Circular Birefringence. By applying the MOCB experimental technique, it is possible to differentiate between the cancer and non-cancer patients. The paper introduces a purely molecular physics approach for description of the cancer/recovered and also non-cancer patients status.

“To Understand Russia”? Question about Russia as a Philosophical Problem  [PDF]
Marian Broda
Open Journal of Philosophy (OJPP) , 2014, DOI: 10.4236/ojpp.2014.44063
Abstract: The aim of this article is to identify and explain the cognitive possibilities which—for the sake of analysis of the questions about Russia and the efforts to “understand Russia”, for centuries central to the Russian intellectual and cultural tradition—are offered by the post-Kantian philosophical perspective. The fundamental research method is the analysis of texts in which representative members of the Russian philosophical and broader intelectual-cultural tradition undertake selfcoqnitive attempts, asking questions about Russia. The analyses which I have undertaken, show that in the post-Kantian theoretical perspective it is possible to strive for recognition of the basic assumptions, structures, properties and conditions of the sense-making processes, which are invisible for such a subject, which is directly involved in a specific cognitive relation. It is then possible and required to determine which forms and structures can appear—and why—within those basic assumptions or conditions as important—from the perspective of subject, object or axiology—the recognition of factors, conditions and limits of heterogenization of the basic structural and substantial solutions, the recurring relations of senses and the types of their specifications, and the scope and methods of permitted self-problematization. In conclusion, I wish to state that the questions about Russia are, therefore, truly questions of their authors about themselves and their way of understanding the world.
Molecular Marker of Tumours  [PDF]
Marian Surma
Journal of Cancer Therapy (JCT) , 2016, DOI: 10.4236/jct.2016.710070
Abstract: Molecular structure of the marker of tumour is determined by magneto-optical analysis of blood serum. The marker is the laevorotatory enantiomer of alanine. The cancer status of a subject is described by the number of molecules of the laevorotatory alanine enantiomer (-)ρ and the effectiveness of therapy is measured by the number of molecules of the dextrorotatory alanine enantiomer (+)ρ. The values of (-)ρ and (+)ρ are determined separately for the patient before and after therapy.
The role of stepped surfaces on the magnetotransport in strained thin films of La0.67Ca0.33MnO3
C. Beekman,J. Aarts
Physics , 2012,
Abstract: We report a comparative study of the properties of very thin films of La0.67Ca0.33MnO3 grown epitaxially under strain on flat SrTiO3 (STO) and on 1 deg miscut STO. For the films on flat STO the transport properties show well-known behavior, namely values of the metal-insulator transition temperature which are strongly reduced with respect to the bulk value. The reduction in films on miscut STO is significantly less strong than in films on flat STO, even though they appear similar as to strain state. Moreover, the residual resistance at low temperatures is lower than for the case of flat films. Magnetically, we find reduced values of the saturation magnetization with respect to the bulk value, indicating the presence of a dead layer in both cases. We argue that the higher density of the step edges on the miscut substrates lead to strain relaxation in the form of point defects and an increased electronic bandwidth, which actually make the electronic properties more robust.
Criteria for the absence of quantum fluctuations after spontaneous symmetry breaking
Aron J. Beekman
Physics , 2014, DOI: 10.1016/j.aop.2015.07.008
Abstract: The lowest-energy state of a macroscopic in which symmetry is spontaneously broken, is a very stable wavepacket centered around a spontaneously chosen, classical direction in symmetry space. However, for a Heisenberg ferromagnet the quantum groundstate is exactly the classical groundstate. This coincides with other exceptional properties of the ferromagnet, including spontaneous time-reversal symmetry breaking, a reduced number of Nambu-Goldstone modes and the absence of a thin spectrum (Anderson tower of states). Recent discoveries of other non-relativistic systems with fewer Nambu-Goldstone modes suggest these specialties apply there as well. I establish precise criteria for the absence of quantum fluctuations and all the other features. In particular, it is not sufficient that the order parameter commute with the Hamiltonian. It leads to a measurably larger coherence time of superpositions in small but macroscopic systems.
Decreased Levels of Bisecting GlcNAc Glycoforms of IgG Are Associated with Human Longevity
L. Renee Ruhaak,Hae-Won Uh,Marian Beekman,Carolien A. M. Koeleman,Cornelis H. Hokke,Rudi G. J. Westendorp,Manfred Wuhrer,Jeanine J. Houwing-Duistermaat,P. Eline Slagboom,André M. Deelder
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0012566
Abstract: Markers for longevity that reflect the health condition and predict healthy aging are extremely scarce. Such markers are, however, valuable in aging research. It has been shown previously that the N-glycosylation pattern of human immunoglobulin G (IgG) is age-dependent. Here we investigate whether N-linked glycans reflect early features of human longevity.
Lipoprotein Particle Profiles Mark Familial and Sporadic Human Longevity
Bastiaan T Heijmans ,Marian Beekman,Jeanine J Houwing-Duistermaat,Mark R Cobain,Jonathan Powell,Gerard Jan Blauw,Frans van der Ouderaa,Rudi G. J Westendorp,P. Eline Slagboom
PLOS Medicine , 2006, DOI: 10.1371/journal.pmed.0030495
Abstract: Background Genetic and biochemical studies have indicated an important role for lipid metabolism in human longevity. Ashkenazi Jewish centenarians and their offspring have large low-density lipoprotein (LDL) and high-density lipoprotein (HDL) particles as compared with control individuals. This profile also coincided with a lower prevalence of disease. Here, we investigate whether this observation can be confirmed for familial longevity in an outbred European population and whether it can be extended to sporadic longevity in the general population. Methods and Findings NMR-measured lipoprotein profiles were analyzed in 165 families from the Leiden Longevity Study, consisting of 340 long-lived siblings (females >91 y, males >89 y), 511 of their offspring, and 243 partners of the offspring. Offspring had larger (21.3 versus 21.1 nm; p = 0.020) and fewer (1,470 versus 1,561 nmol/l; p = 0.011) LDL particles than their same-aged partners. This effect was even more prominent in the long-lived siblings (p < 10?3) and could be pinpointed to a reduction specifically in the concentration of small LDL particles. No differences were observed for HDL particle phenotypes. The mean LDL particle sizes in 259 90-y-old singletons from a population-based study were similar to those in the long-lived siblings and thus significantly larger than in partners of the offspring, suggesting that the relevance of this phenotype extends beyond familial longevity. A low concentration of small LDL particles was associated with better overall health among both long-lived siblings (p = 0.003) and 90-y-old singletons (p = 0.007). Conclusions Our study indicates that LDL particle profiles mark both familial and sporadic human longevity already in middle age.
Page 1 /1412
Display every page Item

Copyright © 2008-2017 Open Access Library. All rights reserved.