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Search Results: 1 - 10 of 438033 matches for " Maria del Mar;Ponce-de-León-Rosales "
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Incidence and risk factors for cutaneous adverse drug reactions in an intensive care unit
Campos-Fernández, Maria del Mar;Ponce-de-León-Rosales, Samuel;Archer-Dubon, Carla;Orozco-Topete, Rocío;
Revista de investigación clínica , 2005,
Abstract: objective. to evaluate the incidence of adverse cutaneous drug reactions in intensive care unit patients. design. cohort study. setting. general adult intensive care unit of an institutional tertiary care hospital. patients. patients in the intensive care unit during a consecutive 8-month period were examined for adverse cutaneous drug reactions. results. patients in the intensive care unit have an incidence of 11.6% of adverse cutaneous drug reactions. associated risk factors were female gender, obesity, age over 60 and immune dysregulation (systemic lupus erythematosus, dysthyroidism, and antiphospholipid antibodies syndrome). few patients had previous history of adverse cutaneous drug reactions. antimicrobials were the main drug involved. morbilliform rash followed by urticary were the most frequently observed reactions. interestingly, over 50% of patients with massive edema -independent of etiology- died. conclusions. intensive care unit patients are particularly at risk for developing an adverse cutaneous drug reaction.
Factores relacionados con la percepción subjetiva de la calidad de vida de pacientes con diabetes
árcega-Domínguez, Arturo;Lara-Mu?oz, Carmen;Ponce-de-León-Rosales, Sergio;
Revista de investigación clínica , 2005,
Abstract: objective. to determine the relationship between some clinical and psychosocial factors and the quality of life of a group of diabetic patients. method. a cross sectional study was done with diabetic patients attending a primary care unit. quality of life was evaluated with a verbal global scale. the clinical and psychosocial factors studied were: type of diabetes, duration of the disease, type of treatment, associated diseases, complications, metabolic control (glycosylated hemoglobin), treatment compliance, coping styles, negative attitude to disease, social support, and socioeconómica! level. results. we interviewed 173 patients, most women (73%), most type 2 (95%). we found that being a woman was a factor negatively related to quality of life. of clinical variables, only duration of disease was slightly correlated with quality of life (-0.14). psychological and social variables were significantly correlated with quality of life. we performed a stepwise multiple regression analysis and we found that seven psychosocial variables explained 30% of variance of quality of life. conclusions. our results indicate that clinical factors did not correlate with quality of life. it is the way the patient lives with diabetes and not the diabetes by itself what affects the quality of life of diabetic patients. some psychological and social variables were significantly related to quality of life of these patients.
Eva Sanz-Arazuri,Ana Ponce-de-León-Elizondo,María ángeles Valdemoros-San-Emeterio
Journal of Sports Science and Medicine , 2012,
Abstract: The purpose of this study was to determine some parental predictors of physical inactivity in Spanish adolescents. The sample comprised 1,978 children, aged between 12 and 16 years. A quantitative and qualitative technical triangulation was employed. The study analyzed data of the parents' educational level, the importance they grant to physical-sport activities, and their physical-sport practice. Quantitative technique: a questionnaire (MACOFYD) was used to collect the data. Descriptive, bivariate, and multinomial regression analyses were employed. Statistical significance was set at p < 0.05. Qualitative technique: four discussion groups were conducted, consisting of parents, physical education teachers, teachers of other subjects, and children aged between 12 and 16 years. The results indicated that adolescents are four times more likely to be physically inactive if their parents have never exercised (odds ratio [OR] = 4.065, and = 3.487, for the fathers and mothers, respectively, p < 0.05). When parents grant "some" or "much" importance to physical-sport practice, adolescents are less likely to be physically inactive (OR = 0.185 and 0.118 respectively, p < 0.01). No significant correlation was found between adolescents' physical-sport activity and parents' educational level. However, young people reproach their parents because they emphasize academic goals more than physical-sport practice-an observation that teachers also confirm. Young people perceive their parents as being the education agents with the greatest influence over their inactive lifestyles. Many parents are unaware of their influence and, therefore, do not take responsibility, declaring that the teachers' influence is greater
Pathogenicity island cag, vacA and IS605 genotypes in Mexican strains of Helicobacter pylori associated with peptic ulcers
Fernando Antonio-Rincón, Yolanda López-Vidal, Gonzalo Castillo-Rojas, Eduardo C Lazcano-Ponce, Sergio Ponce-de-León, María L Tabche-Barrera, Germán R Aguilar-Gutiérrez
Annals of Clinical Microbiology and Antimicrobials , 2011, DOI: 10.1186/1476-0711-10-18
Abstract: The cag PAI integrity was performed by detection of eleven targeted genes along this locus using dot blot hybridization and PCR assays. The vacA allelic, cag PAI genotype 1 and IS605 status were determined by PCR analysis.Groups of 16-17 isolates (n = 50) from two patients with NPU, NBPU, and BPU, respectively, were studied. 90% (45/50) of the isolates harbored a complete cag PAI. Three BPU isolates lacked the cag PAI, and two of the NBPU had an incomplete cag PAI: the first isolate was negative for three of its genes, including deletion of the cagA gene, whereas the second did not have the cagM gene. Most of the strains (76%) had the vacA s1b/m1 genotype; meanwhile the IS605 was not present within the cag PAI of any strain but was detected elsewhere in the genome of 8% (4/50).The patients had highly virulent strains since the most of them possessed a complete cag PAI and had a vacA s1b/m1 genotype. All the isolates presented the cag PAI without any IS605 insertion (genotype 1). Combined vacA genotypes showed that 1 NPU, 2 NBPU, and 1 BPU patients (66.6%) had a mixed infection; coexistence of H. pylori strains with different cag PAI status was observed in 1 NBPU and 2 BPU (50%) of the patients, but only two of these patients (NBPU and BPU) had different vacA genotypes.H. pylori is a well-recognized pathogen that chronically infects the stomach of up to 50% of the world's human population. The prevalence of H. pylori is high in developing countries; in Mexico its seroprevalence is 66% of the general population and is common in asymptomatic population [1-5].There are two genotypic characteristics of virulent H. pylori strains: the vacA gene, and the cag PAI region. Virtually all H. pylori strains have a copy of vacA, but the structure among alleles varies in three regions: the signal (s) region that is present as type s1 (subtype a, b and c) or type s2, the intermediate (i) region that exists in subtype 1 and 2, and the middle (m) region that exists in three different
Teorizar la experiencia profesional del trabajo social Theorizing the Professional Experience of Social Work
Laura Ponce-de-León-Romero
Portularia : Revista de Trabajo Social , 2012, DOI: 10.5218/prts.2012.0015
Abstract: El objetivo de este trabajo es analizar el proceso histórico de la profesión de Trabajo Social, utilizando como elemento integrador el binomio práctica-teoría. La experiencia y la formación de un cuerpo teórico sólido y amplio de conocimiento han generado el reconocimiento profesional del Trabajo Social, desligándose de sus raíces benéfico-asistenciales. También se analizan las áreas, las teorías vigentes y las nuevas tendencias emergentes que han dado contenido a la sistematización y a la complejidad metodológica del Trabajo Social. The aim of this work is to analyze the historical process of the profession of Social Work using the binomial practice-theory as an integrating element. The experience and the formation of a solid and broad theoretical basis of knowledge have enabled the recognition of professional Social Work, leaving aside its charitable roots. We analyze current theories and trends that have given substance to the systematization and methodological complexity of Social Work.
Distributed Diagnosability Analysis with Petri Nets
Laura Brandán-Briones,Agnes Madalinski,Hernán Ponce-de-León
Computer Science , 2015,
Abstract: We propose a framework to distributed diagnos- ability analysis of concurrent systems modeled with Petri nets as a collection of components synchronizing on common observable transitions, where faults can occur in several components. The diagnosability analysis of the entire system is done in parallel by verifying the interaction of each component with the fault free versions of the other components. Furthermore, we use existing efficient methods and tools, in particular parallel LTL-X model checking based on unfoldings, for diagnosability verification.
Unfolding-Based Process Discovery
Hernán Ponce-de-León,César Rodríguez,Josep Carmona,Keijo Heljanko,Stefan Haar
Computer Science , 2015,
Abstract: This paper presents a novel technique for process discovery. In contrast to the current trend, which only considers an event log for discovering a process model, we assume two additional inputs: an independence relation on the set of logged activities, and a collection of negative traces. After deriving an intermediate net unfolding from them, we perform a controlled folding giving rise to a Petri net which contains both the input log and all independence-equivalent traces arising from it. Remarkably, the derived Petri net cannot execute any trace from the negative collection. The entire chain of transformations is fully automated. A tool has been developed and experimental results are provided that witness the significance of the contribution of this paper.
High Diversity of vacA and cagA Helicobacter pylori Genotypes in Patients with and without Gastric Cancer
Yolanda López-Vidal, Sergio Ponce-de-León, Gonzalo Castillo-Rojas, Rafael Barreto-Zú?iga, Aldo Torre-Delgadillo
PLOS ONE , 2008, DOI: 10.1371/journal.pone.0003849
Abstract: Background Helicobacter pylori is associated with chronic gastritis, peptic ulcers, and gastric cancer. The aim of this study was to assess the topographical distribution of H. pylori in the stomach as well as the vacA and cagA genotypes in patients with and without gastric cancer. Methodology/Principal Findings Three gastric biopsies, from predetermined regions, were evaluated in 16 patients with gastric cancer and 14 patients with dyspeptic symptoms. From cancer patients, additional biopsy specimens were obtained from tumor centers and margins; among these samples, the presence of H. pylori vacA and cagA genotypes was evaluated. Positive H. pylori was 38% and 26% in biopsies obtained from the gastric cancer and non-cancer groups, respectively (p = 0.008), and 36% in tumor sites. In cancer patients, we found a preferential distribution of H. pylori in the fundus and corpus, whereas, in the non-cancer group, the distribution was uniform (p = 0.003). A majority of the biopsies were simultaneously cagA gene-positive and -negative. The fundus and corpus demonstrated a higher positivity rate for the cagA gene in the non-cancer group (p = 0.036). A mixture of cagA gene sizes was also significantly more frequent in this group (p = 0.003). Ninety-two percent of all the subjects showed more than one vacA gene genotype; s1b and m1 vacA genotypes were predominantly found in the gastric cancer group. The highest vacA-genotype signal-sequence diversity was found in the corpus and 5 cm from tumor margins. Conclusion/Significance High H. pylori colonization diversity, along with the cagA gene, was found predominantly in the fundus and corpus of patients with gastric cancer. The genotype diversity observed across systematic whole-organ and tumor sampling was remarkable. We find that there is insufficient evidence to support the association of one isolate with a specific disease, due to the multistrain nature of H. pylori infection shown in this work.
Microbiological Implications of Periurban Agriculture and Water Reuse in Mexico City
Marisa Mazari-Hiriart, Sergio Ponce-de-León, Yolanda López-Vidal, Pilar Islas-Macías, Rosa Isabel Amieva-Fernández, Francisco Qui?ones-Falconi
PLOS ONE , 2008, DOI: 10.1371/journal.pone.0002305
Abstract: Background Recycled treated or untreated wastewater represents an important health challenge in developing countries due to potential water related microbiological exposure. Our aim was to assess water quality and health implications in a Mexico City periurban agricultural area. Methodology/Principal Findings A longitudinal study in the Xochimilco wetland area was conducted, and 42 sites were randomly selected from 211, including irrigation water canals and effluents of treatment plants. Sample collection took place during rainy and dry seasons (2000–2001). Microbiological parameters (total coliforms, fecal coliforms, streptococci/enterococci, and bacteria other than Vibrio grown on TCBS), Helicobacter pylori, and physicochemical parameters including trihalomethanes (THM) were determined. Fecal coliforms and fecal streptococci are appropriate indicators of human or animal fecal contamination. Fecal coliform counts surpass Mexican and World Health Organization irrigation water guidelines. Identified microorganisms associated with various pathologies in humans and domestic animals comprise Escherichia coli, Klebsiella spp., Salmonella spp., Enterobacter spp., Enterococcus spp., and Pseudomonas spp; H. pylori was also present in the water. An environmental characteristic of the canal system showed high Total Organic Carbon content and relatively low dissolved oxygen concentration; residual chlorine as a disinfection control is not efficient, but THMs do not represent a problem. During the rainy season, temperature and conductivity were higher; in contrast, pH, dissolved oxygen, ammonia, and residual chlorine were lower. This is related with the continuous load of feces from human and animal sources, and to the aquatic systems, which vary seasonally and exhibit evidence of lower water quality in effluents from treatment plants. Conclusions/Significance There is a need for improvement of wastewater treatment systems, as well as more efficient monitoring, regulation, and enforcement procedures for wastewater disposal into bodies of water.
Surveillance of nosocomial infections in a Mexican community hospital: how are we doing?
García-García,Lourdes; Jiménez-Corona,María-Eugenia; Ramírez-López,Laura-Elizabeth; Báez-Salda?a,Renata; Ferreyra-Reyes,Leticia; Ferreira-Guerrero,Elizabeth; Cano-Arellano,Bulmaro; Cruz-Hervert,Pablo; Téllez-Vázquez,Norma Araceli; Verduzco-Rodríguez,Leonardo; Jaramillo-Cosme,Yolanda; Luna-Téllez,Eleazar; León-Rosales,Samuel Ponce de;
Salud Pública de México , 2010, DOI: 10.1590/S0036-36342010000600005
Abstract: objective. to compare the nosocomial infection (ni) rate obtained from a retrospective review of clinical charts with that from the routine nosocomial infection surveillance system in a community hospital. material and methods. retrospective review of a randomized sample of clinical charts.results were compared to standard surveillance using crude and adjusted analyses. results. a total of 440 discharges were reviewed, there were 27 episodes of nis among 22 patients. cumulated incidence was 6.13 ni per 100 discharges. diarrhea, pneumonia and peritonitis were the most common infections. predictors of ni by cox regression analysis included pleural catheter (hr 16.38), entry through the emergency ward, hospitalization in the intensive care unit (hr 7.19), and placement of orotracheal tube (hr 5.54). conclusions. frequency of nis in this community hospital was high and underestimated. we identified urgent needs in the areas of training and monitoring.
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