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Search Results: 1 - 10 of 108746 matches for " Maria Rita Leal;Ferreira-Gon?alves "
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A regress?o observada no tratamento do desvio fonológico
Checalin, Mard?nia Alves;Ghisleni, Maria Rita Leal;Ferreira-Gonalves, Giovana;Keske-Soares, Márcia;Mota, Helena Bolli;
Pró-Fono Revista de Atualiza??o Científica , 2010, DOI: 10.1590/S0104-56872010000300034
Abstract: background: relapse in phonological performance. aim: to verify relapse in the phonological performance related to sound production in the treatment of phonological disorder. method: three subjects with phonological disorders, aged 6:0, 7:0, 7:0 years, were treated for phoneme /r/ using the abab-withdrawal and multiple probes model. after a cycle of treatment, the phonemes that presented relapse in terms of production percentage were compared. results: the results indicate that relapse occurred in the phonological system of all subjects. the involved features were mainly related to the main category. conclusion:a relationship between the features of the treated phoneme and the ones that presented relapse was observed for all of the studied cases.
Histopathological and ultrastructural aspects of mice lungs experimentally infected with dengue virus serotype 2
Barreto, Débora Ferreira;Takiya, Christina Maeda;Schatzmayr, Hermann Gonalves;Nogueira, Rita Maria Ribeiro;Farias-Filho, José da Costa;Barth, Ortrud Monika;
Memórias do Instituto Oswaldo Cruz , 2007, DOI: 10.1590/S0074-02762007005000007
Abstract: histological and ultrastructural alterations in lung tissue of balb/c mice infected with dengue virus serotype 2 (non-neuroadapted), by intraperitoneal and intravenous routes were analyzed. lung tissues were processed following the standard techniques for photonic and electron transmission microscopies. histopathological and ultrastructural studies showed interstitial pneumonia, characterized by the presence of mononuclear cells. in the mouse model, the dengue virus serotype 2 seems to led to a transient inflammatory process without extensive damage to the interalveolar septa, but caused focal alterations of the blood-exchange barrier. endothelial cells of blood capillaries exhibited phyllopodia suggesting activation by presence of dengue virus. morphometrical analysis of mast cells showed an expressive increase of the number of these cells in peribronchiolar spaces and adjacent areas to the interalveolar septa. alveolar macrophages showed particles dengue virus-like inside rough endoplasmic reticulum and golgi complex, suggesting viral replication. the tissue alterations observed in our experimental model were similar to the observed in human cases of dengue fever and dengue hemorrhagic fever. our results show that balb/c mice are permissive host for dengue virus serotype 2 replication and therefore provides an useful model to study of morphological aspects of dengue virus infection.
Estresse oxidativo: conceito, implica??es e fatores modulatórios
Barbosa, Kiriaque Barra Ferreira;Costa, Neuza Maria Brunoro;Alfenas, Rita de Cássia Gonalves;De Paula, Sérgio Oliveira;Minim, Valéria Paula Rodrigues;Bressan, Josefina;
Revista de Nutri??o , 2010, DOI: 10.1590/S1415-52732010000400013
Abstract: there is evidence that oxidative stress, defined as a persistent imbalance between the production of highly oxidative compounds and antioxidant defenses, leads to tissue damage. oxygen metabolism generates free radicals and/or non-radical reactive oxygen species. the mitochondria, through the electron transport chain, are the main generator of these species. the antioxidant defense system has the function of inhibiting and/or reducing the damage caused by the deleterious free radicals and/or non-radical reactive oxygen species. this system is divided into enzymatic (superoxide dismutase, catalase and glutathione peroxidase), and nonenzymatic. the nonenzymatic system consists of a variety of antioxidant substances, which may be endogenous or dietary. this study proposed to review the main mechanisms of reactive oxygen species generation and the role of the most relevant agents of the antioxidant defense system on the biomarkers of oxidative stress. the main exogenous factors that modulate oxidative stress will also be discussed.
A greve académica de 1907. Suas repercuss?es políticas e educacionais
Gonalves,Maria Neves Leal;
Revista Lusófona de Educa??o , 2007,
Abstract: this article aims to revisit the 1970?s portuguese academic strike while integrating it in the decline of the constitutional monarchy scenery in the promising atmosphere of the new republican order. firstly, this article considers the origin, development and the consequences of that student strike. then, we have studied some of the parliament speeches that such historical moment has forced to emerge at the portuguese parliament. we stress and focus in antónio josé de almeida?s eloquent discourses for he was one of the great republicans of his epoch.
Prevalência de diabetes melito e tolerancia à glicose diminuída na popula??o urbana de 30 a 79 anos da cidade de S?o Carlos, S?o Paulo
Bosi, Paula Lima;Carvalho, Arlety Morais;Contrera, Daniele;Casale, Guilherme;Pereira, Marina Alexandre;Gronner, Matheus Ferreira;Diogo, Thatiana Melo;Torquarto, Maria Tereza da Costa Gonalves;Oishi, Jorge;Leal, Angela Merice de Oliveira;
Arquivos Brasileiros de Endocrinologia & Metabologia , 2009, DOI: 10.1590/S0004-27302009000600006
Abstract: objective: to assess the prevalence of diabetes mellitus (dm) and impaired glucose tolerance (igt) in the urban population aged 30-79 years of the city of s?o carlos, s?o paulo, brazil. methods: it was performed a population survey, from august 2007 to june 2008. non diabetic individuals, excluding pregnant women, and those with fasting capillary glycemia < 199 mg/dl were administered oral glucose tolerance test and classified as diabetic, with igt or with normal glucose tolerance. results: the number of individuals who participated in the study was 1,116. the overall rates of dm and igt were 13.5% and 5%, respectively. dm and igt were associated with age, education, body mass index and waist. they were not associated with gender, race or income. conclusions: the prevalence of dm has increased when compared with previous studies in brazil and in the state. improvement in the diagnosis has occurred, however, treatment requires optimization.
Dengue virus type 4 in Niterói, Rio de Janeiro: the role of molecular techniques in laboratory diagnosis and entomological surveillance
Castro, Márcia Gonalves de;Nogueira, Rita Maria Ribeiro;Filippis, Ana Maria Bispo de;Ferreira, Anielly Alves;Lima, Monique da Rocha Queiroz;Faria, Nieli Rodrigues da Costa;Nogueira, Fernanda de Bruycker;Sim?es, Jaqueline Bastos Santos;Nunes, Priscila Conrado Guerra;Sampaio, Simone Alves;Louren?o-de-Oliveira, Ricardo;Santos, Flávia Barreto dos;
Memórias do Instituto Oswaldo Cruz , 2012, DOI: 10.1590/S0074-02762012000700017
Abstract: in niterói, state of rio de janeiro, dengue virus type 4 (denv-4) was isolated for the first time in march 2011. we analysed the laboratory findings of the first cases and evaluated the use of molecular techniques for the detection of denv-4 in aedes aegypti that were field-caught. conventional reverse transcriptase-polymerase chain reaction (rt-pcr) and simplexatm dengue real-time rt-pcr confirmed denv-4 infection in all cases. additionally, denv-4 was confirmed in a female ae. aegypti with 1.08 x 103 copies/ml of virus, as determined by quantitative real-time rt-pcr. this is the first time the simplexatm dengue real-time assay has been used for the classification of cases of infection and for entomological investigations. the use of these molecular techniques was shown to be important for the surveillance of dengue in humans and vectors.
Estudo da anatomia do nervo tibial e seus ramos ao nível do ter?o distal da perna
Torres, André Leal Gonalves;Ferreira, Marcus Castro;
Acta Ortopédica Brasileira , 2012, DOI: 10.1590/S1413-78522012000300005
Abstract: objective: determine, through dissection in fresh cadavers, the topographic anatomy of the tibial nerve and its branches at the ankle, in relation to the tarsal tunnel. methods: bilateral dissections were performed on 26 fresh cadavers and the locations of the tibial nerve bifurcation and its branches were measured in millimeters. for the calcaneal branches, the amount and their respective nerves of origin were also analyzed. results: the tibial nerve bifurcation occurred under the tunnel in 88% of the cases and proximally in 12%. as for the calcaneal branches, the medial presented with one (58%), two (34%) and three (8%) branches, with the most common source occurring in the tibial nerve (90%) and the lower with a single branch per leg and lateral plantar nerve as origin most common (70%). level of evidence, v expert opinion.
Do ensino da língua à língua no ensino
Olívia Maria Ferreira Gonalves Figueiredo
Linguarum Arena : Revista do Programa Doutoral em Didáctica de Línguas da Universidade do Porto , 2011,
Abstract: In this article we offer an overview of the main trends that have been the methodological basis of the field of mother tongue didactics, particular by over the last fifty years, relating essential aspects such as: psychological, linguistic and pedagogical. Methods based on essential traits of communicative methodology are analysed. The need to establish principles aimed at pointing out each learning situation are highlighted.
Regulation of Inflammatory Chemokine Receptors on Blood T Cells Associated to the Circulating Versus Liver Chemokines in Dengue Fever
Luzia Maria de-Oliveira-Pinto, Cíntia Ferreira Marinho, Tiago Fajardo Povoa, Elzinandes Leal de Azeredo, Luiza Assed de Souza, Luiza Damian Ribeiro Barbosa, Ana Rita C. Motta-Castro, Ada M. B. Alves, Carlos André Lins ávila, Luiz José de Souza, Rivaldo Venancio da Cunha, Paulo Vieira Damasco, Marciano Viana Paes, Claire Fernandes Kubelka
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0038527
Abstract: Little is known about the role of chemokines/chemokines receptors on T cells in natural DENV infection. Patients from DENV-2 and -3- outbreaks were studied prospectively during the acute or convalescent phases. Expression of chemokine receptor and activation markers on lymphocyte subpopulations were determined by flow cytometry analysis, plasma chemokine ligands concentrations were measured by ELISA and quantification of CCL5/RANTES+ cells in liver tissues from fatal dengue cases was performed by immunochemistry. In the acute DENV-infection, T-helper/T-cytotoxic type-1 cell (Th1/Tc1)-related CCR5 is significantly higher expressed on both CD4 and CD8 T cells. The Th1-related CXCR3 is up-regulated among CD4 T cells and Tc2-related CCR4 is up-regulated among CD8 T cells. In the convalescent phase, all chemokine receptor or chemokine ligand expression tends to reestablish control healthy levels. Increased CCL2/MCP-1 and CCL4/MIP-1β but decreased CCL5/RANTES levels were observed in DENV-patients during acute infection. Moreover, we showed an increased CD107a expression on CCR5 or CXCR3-expressing T cells and higher expression of CD29, CD44HIGH and CD127LOW markers on CCR4-expressing CD8 T cells in DENV-patients when compared to controls. Finally, liver from dengue fatal patients showed increased number of cells expressing CCL5/RANTES in three out of four cases compared to three death from a non-dengue patient. In conclusion, both Th1-related CCR5 and CXCR3 among CD4 T cells have a potential ability to exert cytotoxicity function. Moreover, Tc1-related CCR5 and Tc2-related CCR4 among CD8 T cells have a potential ability to exert effector function and migration based on cell markers evaluated. The CCR5 expression would be promoting an enhanced T cell recruitment into liver, a hypothesis that is corroborated by the CCL5/RANTES increase detected in hepatic tissue from dengue fatal cases. The balance between protective and pathogenic immune response mediated by chemokines during dengue fever will be discussed.
Regulation of Respiratory and Ligninolytic Enzyme Activity of Lentinula edodes by Selenium  [PDF]
Regiane Gonalves Feitosa Leal Nunes, Jose Maria Rodrigues da Luz, Elizabete Fantuzzi, Maria Catarina Megumi Kasuya, Maria Cristina Dantas Vanetti
Advances in Microbiology (AiM) , 2013, DOI: 10.4236/aim.2013.38A006

The production of mushrooms enriched with essential elements, e.g. selenium, for human health is an interesting strategy to improve the functional foods supply. The selenium is an essential mineral and makes part of structure of enzymes involved in the oxidative metabolism. However, the selenium effect on the activity of respiratory and lignocellulolytic enzymes has not been considered. The understanding of this effect is important to determine the selenium concentration that increases the mushroom productivity and the degradation rate of the substrate. In this study, it was observed reduction of the respiratory activity of Lentinula edodes (Berk.) Pegler, the shiitake mushroom, in function of the increasing of the sodium selenite concentration in the substrate (p < 0.05). Selenium did not inhibit the activity of the hydrolytic enzymes (cellulase and xylanase), but it increased the activity of the oxidative enzyme (laccase). Respiratory activity of L. edodes has a negative correlation with sodium selenite concentration added in substrate. Thus is important to define the ideal dose of selenium to be added to the substrate for increasing lignocellulosic residues degradation and, consequently, guarantee a higher production of Se-enriched mushrooms.

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