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Search Results: 1 - 10 of 72257 matches for " Maria Emilia Cosenza;Cosenza "
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Interictal brain SPECT in patients with medically refractory temporal lobe epilepsy
ANDRAUS MARIA EMILIA COSENZA
Arquivos de Neuro-Psiquiatria , 2000,
Abstract:
Non-epileptiform EEG abnormalities: an overview
Andraus, Maria Emilia Cosenza;Alves-Leon, Soniza Vieira;
Arquivos de Neuro-Psiquiatria , 2011, DOI: 10.1590/S0004-282X2011000600020
Abstract: more than 80 years after its introduction by hans berger, the electroencephalogram (eeg) remains as an important supplementary examination in the investigation of neurological disorders and gives valuable and accurate information about cerebral function. abnormal eeg findings may include ictal patterns, interictal epileptiform activity and non-epileptiform abnormalities. the aim of this study is to make an overview on the main non-epileptiform eeg abnormalities, emphasizing the pathologic findings and the importance of their recognition, excluding periodic patterns and eeg physiologic changes. scientific articles were selected from medline and pubmed database. the presence of non-epileptiform eeg abnormalities provide evidence of brain dysfunction that are not specific to a particular etiology and may be related to a number of disorders affecting the brain. although these abnormalities are not specific, they can direct attention to the diagnostic possibilities and guide the best treatment choice.
SPECT cerebral interictal em pacientes com epilepsia do lobo temporal de difícil controle
Andraus Maria Emilia Cosenza,Cosenza Carlos Alberto Nunes,Fonseca Léa Mirian Barbosa da,Andraus Cesar Fantezia
Arquivos de Neuro-Psiquiatria , 2002,
Abstract: O objetivo desse estudo foi avaliar a utilidade do SPECT cerebral interictal na localiza o do foco epileptogênico em 23 pacientes do Ambulatório de Epilepsias do Hospital Universitário Clementino Fraga Filho (HUCFF/UFRJ), com epilepsia do lobo temporal (ELT) de difícil controle e tomografia computadorizada (TC) do cranio normal, estudando a correla o entre SPECT interictal, eletrencefalograma (EEG) e, em 11 casos, ressonancia magnética (RM) do cranio, e comparar os resultados com os de outras seis séries da literatura. Doze (52,2%) pacientes apresentaram SPECT anormal. Entre esses, cinco (41,6% dos SPECTs anormais) apresentaram altera o unilateral ao SPECT do mesmo lado do EEG (hipoperfus o em 4 e hiperperfus o em 1), três (25% dos SPECTs anormais) apresentaram hipoperfus o bilateral ao SPECT e altera es também bilaterais ao EEG e 4 (33,3% dos SPECTs anormais) apresentaram hipoperfus o unilateral ao SPECT e EEG bilateral. A análise estatística fundamentou-se na lógica fuzzy. Os índices de correla o entre SPECT X EEG, SPECT X RM e SPECT X EEG X RM foram altamente significativos, com níveis de significancia de 0,01, p < 0,0005 e intervalo de 99% de confian a em todas as correla es. Os estudos de correla o entre as séries estudadas apresentaram resultados semelhantes entre si.
Periodic EEG patterns: importance of their recognition and clinical significance
Andraus, Maria Emilia Cosenza;Andraus, Cesar Fantezia;Alves-Leon, Soniza Vieira;
Arquivos de Neuro-Psiquiatria , 2012, DOI: 10.1590/S0004-282X2012000200014
Abstract: periodic electroencephalographic (eeg) patterns consist of discharges usually epileptiform in appearance, which occur at regular intervals, in critical patients. they are commonly classified as periodic lateralized epileptiform discharges (pleds), bilateral independent pleds or bipleds, generalized epileptiform discharges (gpeds) and triphasic waves. stimulus-induced rhythmic, periodic or ictal discharges (sirpids) are peculiar eeg patterns, which may be present as periodic discharges. the aim of this study is to make a review of the periodic eeg patterns, emphasizing the importance of their recognition and clinical significance. the clinical significance of the periodic eeg patterns is uncertain, it is related to a variety of etiologies, and many authors suggest that these patterns are unequivocally epileptogenic in some cases. their recognition and classification are important to establish an accurate correlation between clinical, neurological, laboratorial and neuroimaging data with the eeg results.
SPECT cerebral interictal em pacientes com epilepsia do lobo temporal de difícil controle
Andraus, Maria Emilia Cosenza;Cosenza, Carlos Alberto Nunes;Fonseca, Léa Mirian Barbosa da;Andraus, Cesar Fantezia;D'Andrea, Isabela;Alves-Leon, Soniza Vieira;
Arquivos de Neuro-Psiquiatria , 2002, DOI: 10.1590/S0004-282X2002000500019
Abstract: the objective of this study was to evaluate the utility of interictal brain spect in localizing the epileptogenic focus in a population of patients of epilepsy clinic of hospital universitário clementino fraga filho (hucff/ufrj), with medically refractory temporal lobe epilepsy (tle) and normal computed tomography (ct) scans, studying the correlation between spect, electroencephalogram (eeg) and, in 11 cases, brain magnectic resonance imaging (mri), and to compare the results to the other six literatura series. twelve (52.2%) patients presented abnormal spect. among these, five (41.6% of abnormal spects) presented unilateral spect changes at the same side of eeg (hypoperfusion in four and hyperperfusion in one), three (25% of abnormal spects) presented bilateral hypoperfusion and bilateral eeg changes too, and four (33.3%) presented unilateral hypoperfusion and bilateral eeg changes. the statistical analysis was based on fuzzy logic. the correlation index among spect x eeg, spect x mri and spect x eeg x mri were highly significant, with signifcance levels at 0.01, p < 0.0005 and trust interval at 99% in all correlations. the correlation studies between the series presented similar results.
Clinical and electroencephalographic characteristics of benign occipital epilepsy of childhood in two tertiary Brazilian hospitals
Alves-Leon, Soniza Vieira;Nunes, Renata Gomes;Andraus, Maria Emilia Cosenza;Biagini Junior, José Carlos;Hemb, Marta;Genofre, Maria Alice;
Arquivos de Neuro-Psiquiatria , 2011, DOI: 10.1590/S0004-282X2011000500014
Abstract: this study intended to investigate the clinical and electroencephalographic benign occipital epilepsy of childhood (boec) characteristics in a population sample of patients from two tertiary brazilian hospitals. we analyzed retrospectively 4912 electroencephalograms (eegs) records, and the included patients were submitted to a new clinical and eeg evaluation. were included 12 (0.92%) patients; 4 (33.3%) with criteria for early boec; 6 (50%) for late form and 2 (16.7%) with superimposed early and late onset forms. after new investigation, 2 (16.7%) had normal eeg; 4 (33.3%) had paroxysms over the occipital region; 3 (25%) over the temporal posterior regions and 3 (25%) over the posterior regions. sharp waves were the predominant change, occurring in 8 (66.6%); spike and slow wave complexes in 1 (8.3%) and sharp and slow wave complexes in 1 (8.3%). vomiting, headache and visual hallucinations were the most common ictal manifestations, presented in 100% of patients with superimposed forms. vomiting were absent in the late form and headache was present in all forms of boec.
Italian Mediterranean river buffalo CSN2 gene structure and promoter analysis
Gianfranco Cosenza,Maria Feligini,Andrea Mancusi,Annalisa D'Avino
Italian Journal of Animal Science , 2010, DOI: 10.4081/ijas.2009.s2.57
Abstract: The nucleotide sequence of the whole buffalo β-casein encoding gene (CSN2) plus 1,476 nt at the 5' flanking region and 51 nt at the 3' flanking region was determined. The gene is spread over 10.2 kb and consists of 9 exons varying in length from 24 (exon 5) to 498 bp (exon 7) and 8 introns from 92 bp (intron 5) to 22 59 bp (intron 1). Furthermore, highly conserved sequences, mainly located in the 5' flanking region, were found between this gene and the β-casein encoding genes of other species. The comparison between the obtained promoter and exonic regions and buffalo sequences present in EMBL evidenced different polymorphic sites. Finally, 5 interspersed repeated elements (4 in the bovine CSN2 gene) were also identified at 3 different locations of the sequenced region: 5' untranscribed region, intron 1, and intron 4.
The Mapping and Characterization of Cruella (Cru), a Novel Allele of Capping Protein α (Cpa), Identified from a Conditional Screen for Negative Regulators of Cell Growth and Cell Division  [PDF]
Ashley Cosenza, Jacob D. Kagey
Advances in Bioscience and Biotechnology (ABB) , 2016, DOI: 10.4236/abb.2016.710036
Abstract: A Flp/FRT EMS mutagenesis screen was conducted in the eye of Drosophila melanogaster on chromosome 2R to identify negative regulators of cell growth and cell division. In addition to the EMS mutation in the mosaic eye, an ark loss of function allele (ark82) was utilized to block apoptosis in the homozygous mutant cells, setting up a screen for conditional regulators of cell growth and cell division. In the present study, we focus on the characterization and mapping of one mutant that resulted from this screen, Cruella (cru). A cross between flies with the flippase enzyme directed to the developing eye and flies with the mutations cru, ark82, revealed an unusual phenotype that resulted in the homozygous mutant tissue appearing black, in contrast to the expected red. To map the location of this mutation, complementation tests against the Bloomington deficiency kit were conducted. Cru failed to complement previously characterized alleles of capping protein α (cpa). Thus, cpacru is a novel allele of cpa and displays phenotypes similar to previously characterized alleles such as cpa 107E, cpa 69E, and cpascrd . The human homolog, Cap Z, is conserved in humans and serves a similar role in act in filament regulation.
Ideal speaker-hearer o Sujet Parlant?
Giuseppe Cosenza
Rivista Italiana di Filosofia del Linguaggio , 2012,
Abstract: This paper sketches a comparison between the concepts of the subjectivity in Chomsky’s and Saussure’s language theory. This is important for two principal reasons. First, the current debate in cognitive sciences requires a reflection to be made in the different sciences that are geared towards this paradigm; second, the subjectivity notion and its relative definition, as an object of study, represents the key of the stone arch in the theory of cognitive sciences. The inquiry on the role of the subject in the language studies can contribute to the debate of social and biological aspects in human. Furthermore, linguistic study have always had an important relationship with cognitive science, because both share a fundamental difficulty due to the complexity of their object of study and of the finding of appropriate research methods.
A eficácia informativa da demonstra??o do valor adicionado
Cosenza, José Paulo;
Revista Contabilidade & Finan?as , 2003, DOI: 10.1590/S1519-70772003000400001
Abstract: nowadays, the global environment is characterized by significant changes in the social, political and economic areas with direct impacts on managerial activities, through the imposition of new patterns of competitiveness and a need to change work processes and managerial practices. in this context, the traditional accounting information does not totally attend the users' new demands, whose interests are different from those contemplated in the traditional accounting reports. the value added statement is part of this new group of accounting reports created to attend to those emerging needs in a better way, mainly seeking to disclose companies' social activities, clearly presenting the generated wealth so that the whole society knows about the its positive function in the creation of value for the community. this paper presents aspects related to the value added by enterprises and analyzes the importance of this report in making it easier to understand socioeconomic information about the company and its relationship with the environment in which it is located.
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