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Search Results: 1 - 10 of 223091 matches for " Maria Elisabete Amaral de;Nascimento "
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Efeito do peso de tilápia no nilo (Oreochromis niloticus) sobre e rendimento e a qualidade de seus filés defumados com e sem pele
Souza, Maria Luiza Rodrigues de;Viegas, Elisabete M. Macedo;Sobral, Paulo José do Amaral;Kronka, Sérgio do Nascimento;
Ciência e Tecnologia de Alimentos , 2005, DOI: 10.1590/S0101-20612005000100009
Abstract: the objective of this study was to evaluate the effect of different weights of nile tilapia (oreochromis niloticus) on yield and quality of smoked and in natura fillets, with and without skin. one hundred tilapias, divided into three weight classes (c1=500-600g; c2=601-700g; c3=701-800g) were used. two fillet types, with skin and without skin were removed from each sample, salted and hot smoked. weight affected yield of in natura (c1 = 38.54; c2 = 40.23 e c3 = 40.47%) and smoked fillets (c1 = 22.97; c2 = 24.51 e c3 = 24.68%), and in natura fillet mass index (c1 = 36.69; c2 = 39.45 e c3 = 41.18 g.cm-2). the latter was higher in classes c2 and c3. fillet with skin had a higher (p<0.05) water activity (0.99) rate than that of fillet without skin (0.98). salt rate was higher (p<0.01) in smoked fillets than in natura ones. it was observed higher salt levels in the c1 skinless class. with the exception of a* and b* in natura fillet, no difference was reported in color. smoked fillets from c3 class fish were more acceptable by judges. in larger fish the equation y= -21.52 + 0.16034x (r=0.80), where x is the weight of fish, may be employed to calculate smoked fillets size, while y= -17.74 + 0.14198x (r=0.81) for smoked skin-less fillets. regardless of skin presence, the smoked fillets from largest fishes (c2 and c3 classes) yielded better results (approximately 24%), as well as in the sensorial analysis, related to salt ratio and general acceptance. fillets in natura showed low values to a* and b*. weight classes and skin presence in the fillets had no influence in composition, but caused a variation in their area and thickness. the largest fillets were with skin, belonging to class c3.
Identification of mechanisms involved in the relaxation of rabbit cavernous smooth muscle by a new nitric oxide donor ruthenium compound
Cerqueira, Jo?o Batista Gadelha de;Gonzaga-Silva, Lúcio Flávio;Silva, Francisco Ordelei Nascimento da;Cerqueira, Jo?o Victor Medeiros de;Oliveira, Ricardo Reges Maia;Moraes, Maria Elisabete Amaral de;Nascimento, Nilberto Robson Falc?o do;
International braz j urol , 2012, DOI: 10.1590/S1677-55382012000500015
Abstract: purpose: the aim of this study was to evaluate the relaxation in vitro of cavernous smooth muscle induced by a new no donor of the complex nitrosil-ruthenium, named trans-[ru(nh3)4(caffeine)(no)]c13 (rut-caf) and sodium nitroprusside (snp). materials and methods: the tissues, immersed in isolated bath systems, were pre-contracted with phenilephrine (pe) (1 μm) and then concentration-response curves (10-12 - 10-4 m) were obtained. to clarify the mechanism of action involved, it was added to the baths odq (10 μm, 30 μm), oxyhemoglobin (10 μm), l-cysteine (100 μm), hydroxicobalamine (100 μm), glibenclamide, iberotoxin and apamine. tissue samples were frozen in liquid nitrogen to measure the amount of cgmp and camp produced. results: the substances provoked significant relaxation of the cavernous smooth muscle. both rut-caf and snp determined dose-dependent relaxation with similar potency (pec50) and maximum effect (emax). the substances showed activity through activation of the soluble guanylyl cyclase (sgc), because the relaxations were inhibited by odq. oxyhemoglobin significantly diminished the relaxation effect of the substances. l-cysteine failed to modify the relaxations caused by the agents. hydroxicobalamine significantly diminished the relaxation effect of rut-caf. glibenclamide significantly increased the efficacy of rut-caf (pec50 4.09 x 7.09). there were no alterations of potency or maximum effect of the substances with the addition of the other ion channel blockers. rut-caf induced production of significant amounts of cgmp and camp during the relaxation process. conclusions: in conclusion, rut-caf causes relaxation of smooth muscle of corpus cavernosum by means of activation of sgc with intracellular production of cgmp and camp; and also by release of no in the intracellular environment. rut-caf releases the no free radical and it does not act directly on the potassium ion channels.
Determination of nimodipine in plasma by HPLC-MS/MS and pharmacokinetic application
Nascimento, Demétrius Fernandes do;Moraes, Manoel Odorico de;Bezerra, Fernando Ant?nio Frota;Pontes, Andréa Vieira;Uchoa, Célia Regina Amaral;Moraes, Renata Amaral de;Leite, Ismenia Osório;Santana, Gilmara Silva de Melo;Santana, Ana Paula Macedo;Leite, Ana Lourdes Almeida e Silva;Pedrazzoli Júnior, José;Moraes, Maria Elisabete Amaral de;
Brazilian Journal of Pharmaceutical Sciences , 2010, DOI: 10.1590/S1984-82502010000400008
Abstract: to develop and validate a rapid, specific and highly sensitive method to quantify nimodipine in human plasma using dibucaine as the internal standard (is). the analyte and is were extracted from plasma samples by liquid-liquid extraction using hexane-ethyl acetate (1:1 v/v). the chromatographic separation was performed on a varian? polaris c18 analytical column (3 μm, 50 x 2.0 mm) and pre-column securityguardtm c18 (4.0 x 3.0 mm) with a mobile phase of acetonitrile-ammonium acetate 0.02 ml/l (80:20v/v). the method had a chromatographic run time of 4.5 min and linear calibration curve over the range of 0.1- 40 ng/ml (r > 0.9938). the limit of quantification was 100 pg/ml. acceptable precision and accuracy were obtained for concentrations over the standard curve ranges. this validated method was successfully applied in determining the pharmacokinetic profile of nimodipine tablets of 30 mg administered to 24 healthy volunteers. the proposed method of analysis provided a sensitive and specific assay for nimodipine determination in human plasma. the time for the determination of one plasma sample was 4.5 min. this method is suitable for the analysis of nimodipine in human plasma samples collected for pharmacokinetic, bioavailability or bioequivalence studies in humans.
O papel das intera es sociais e de atividades propostas para o ensino-aprendizagem de conceitos químicos The role of social interactions and of proposed activities in the teaching and learning of Chemistry
Juciene Moura de Nascimento,Edenia Maria Ribeiro do Amaral
Ciência & Educa??o (Bauru) , 2012, DOI: 10.1590/s1516-73132012000300006
Abstract: Este trabalho teve como objetivo analisar o papel das intera es sociais e de atividades didáticas propostas em aulas de Química. Apresenta discuss es com base nas teorias sociointeracionistas de Vygotsky e Leontiev, suas implica es e abordagens nos diversos processos de constru o de conceitos. O trabalho foi realizado em uma Escola Pública de Pernambuco, onde foram observados doze alunos, os quais participaram de diferentes tipos de atividade em sala de aula. Essas atividades, realizadas em pequenos grupos, sob a supervis o da professora, foram analisadas considerando-se como relevantes as oportunidades de intera o e discuss o que as mesmas possam ter possibilitado entre os alunos durante as aulas. Os resultados apontaram para a importancia do planejamento de atividades que promovam um processo coletivo, cooperativo e interacionista de ensino e aprendizagem, refor ando o papel do outro na forma o mais ampla dos alunos e contribuindo para uma melhor significa o dos conceitos científicos. This study aimed to analyze the role played by social interactions and by didactical activities in chemistry classes. We have taken into account aspects of sociointeractionist theory such as proposed by Vygotsky and Leontiev, and their implications and approaches applied to the processes for concept formation. The investigation was carried in a Public School of Recife, PE - Brazil, where different types of didactical activities were proposed in the chemistry classroom. These activities were performed by students in small groups under teacher supervision and analyzed by considering as relevant opportunities for interaction and discussion among students which started from tasks demanded during the classes. The results pointed out the importance in planning activities which encourage students to engage in a collective, cooperative and interactional process in teaching and learning, reinforcing the role played by pairs in the learning and contributing from students in making scientific concepts meaningful.
Defuma??o da tilápia do Nilo (Oreochromis niloticus) inteira eviscerada e filé: aspectos referentes às características organolépticas, composi??o centesimal e perdas ocorridas no processamento
Souza, Maria Luiza Rodrigues de;Baccarin, Ana Eliza;Viegas, Elisabete Maria Macedo;Kronka, Sérgio do Nascimento;
Revista Brasileira de Zootecnia , 2004, DOI: 10.1590/S1516-35982004000100005
Abstract: the objective of the experiment was to evaluate the smoking process effect of whole eviscerated and fillet of nile tilapia on the organoleptic characteristics (appearance, aroma, color, flavor, texture, salt content and general acceptance), percent weight loss (pp) and proximate composition. fp1 (whole eviscerated fish, 5 hour smoking) and fp2 (fillet, 4 hour smoking) were compared. scaled, eviscerated fish, fp1 and fillets cut by only one person, fp2 were submitted to brine (30%) and smoking process. average yield for fp1 and fp2 was 63.98% and 27.11%, respectively. average loss weight during smoking for fillet (31.33%) was higher, when compared to whole fish (27.04%). sensorial analysis showed that whole fish was more accepted, regarding flavor and salt content; however, aroma, color and texture were not different between whole fish and fillet. smoking process reduced moisture and increased crude protein, lipid and ash contents. losses were higher for fillet, which presented higher crude protein and lower lipid contents compared to whole fish. it was also verified that fillet flavor can be improved by correcting the brine step.
Biodigest o anaeróbia de dejetos de bovinos leiteiros submetidos a diferentes tempos de reten o hidráulica
Amaral Cecília Maria Costa do,Amaral Luiz Augusto do,Lucas Júnior Jorge de,Nascimento Adjair Ant?nio do
Ciência Rural , 2004,
Abstract: Utilizando-se biodigestores contínuos, abastecidos com dejetos de bovinos leiteiros e operados sob três tempos de reten o hidráulica, avaliou-se o efeito do processo de digest o anaeróbia sobre o número de microrganismos indicadores de polui o fecal, sobre a ocorrência de ovos e larvas de helmintos parasitas de ruminantes, analisando-se também os teores de sólidos totais e voláteis do afluente e dos efluentes, bem como a produ o e a qualidade do biogás produzido. Verificou-se que vinte dias de reten o hidráulica foram suficientes para reduzir significativamente o número de microorganismos indicadores de polui o fecal e a quantidade de ovos de helmintos parasitas de ruminantes. Os resultados obtidos nas análises de sólidos totais e voláteis, bem como a produ o de biogás (m3/dia), permitem concluir que o biodigestor modelo Chinês operado com 20 dias de tempo de reten o hidráulica, apresentou mais eficiência. Vale ressaltar que vinte dias de reten o foram insuficientes para impedir a sobrevivência de larvas de helmintos parasitas de ruminantes.
Effects of hot and cold smoking processes on organoleptic properties, yield and composition of matrinxa fillet
Franco, Maria Luiza Rodrigues de Souza;Viegas, Elisabete Maria Macedo;Kronka, Sérgio Nascimento;Vidotti, Rose Meire;Assano, Marcelo;Gasparino, Eliane;
Revista Brasileira de Zootecnia , 2010, DOI: 10.1590/S1516-35982010000400001
Abstract: the effects of hot (45-90oc/5 hours) and cold (27-45oc/10 hours) smoking processes on the organoleptic properties, yield and composition of matrinxa (brycon cephalus) fillets are evaluated. no significant differences were observed for fillet yield in both non-smoked and smoked fillets. smoking process losses were significantly higher for hot smoked (19.37%) when compared to cold smoked (17.08%). smoking process reduced moisture (in natura = 72.91%, for hot = 58.51% and cold = 59.68%) and increased crude protein, lipid and ash contents. however, there was a significant difference only for protein level between hot smoked (28.07%) and cold smoked (27.14%). cold smoked process resulted in better fillet appearance and color, while hot smoked presented superior flavor, salt content and general acceptance. aroma and texture did not differ significantly among processes. therefore, hot smoking process shows the best results for organoleptic properties and protein levels.
Complica??es e condutas fisioterapêuticas após cirurgia por cancer de mama: estudo retrospectivo
Nascimento, Simony Lira do;Oliveira, Riza Rute de;Oliveira, Mariana Maia Freire de;Amaral, Maria Teresa Pace do;
Fisioterapia e Pesquisa , 2012, DOI: 10.1590/S1809-29502012000300010
Abstract: after breast cancer surgery, women may develop some physical complications. thus, the aims of this study were to investigate the outcome of these women, who participated in a rehabilitation program for one month, as well to identify along two years the most frequent complications and adopted physical therapy conducts. it was a descriptive and retrospective study with 707 medical records of women treated for breast cancer at the women's hospital professor doutor josé aristodemo pinotti, universidade estadual de campinas, between january 2006 and december 2007, admitted in the division of physical therapy. analysis was performed by means, standard deviation, absolute and relative frequencies. by the end of the program, 55% of women were discharged, 17% required additional treatment, and 26% did not join it. the most frequent complications were: pericicatricial adherence (26%), range of motion (rom) restriction (24%), and scar dehiscence (17%). in the first year after surgery (n=460), the main complaints were: pain (28.5%), heaviness (21.5%), and restriction of shoulder range of motion (16.7%); in the second year (n=168), they were pain (48.2%), heaviness (42.8%), and lymphedema (23.2%). it was concluded that most women were discharged in the end of the program and, over the years, they presented reduction of shoulder range of motion frequency and lymphedema increase. care of the arm, home exercises, and self-lymphatic drainage were the most adopted conducts.
Um novo modelo de isolamento do tumor de Walker utilizando o gradiente de Ficoll-Hypaque
Silva, S?nia Leite;Silva, Silvia Fernandes Ribeiro;Farias, Italo Nascimento;Mota, Rosa Salani;Moraes, Maria Elisabete;Campos, Henry de Holanda;Ferreira, Francisco Valdeci;Moraes Filho, Manoel Odorico;
Acta Cirurgica Brasileira , 2006, DOI: 10.1590/S0102-86502006000200009
Abstract: purpose: the purpose was to evaluate a novel technique for isolation of walker's tumoral cells using a ficoll-hypaque gradient and its further influence on tumor development. methods: twenty male wistar rats have been divided in 2 groups: g1= without ficoll, g2= with ficoll. tumor was excised, homogenized and suspended in lactate ringer. a sample of the cell suspension was adjusted at a concentration of 1x106 cells/ml (g1). a second sample was centrifuged on a ficoll-hypaque gradient and the cell concentration was then adjusted (g2). tumor was implanted by subcutaneous injection of 1.0 ml in the right armpit of rats. tumor volume (tv) and tumor weight (tw) were compared in two groups. results: there were no differences between the two groups in tv (g1=17.9±3.8cm3 vs. g2=17.2±4.4cm3; p=0.190) and tw (g1=7.0±1.8g vs. g2=7.3±2.8g; p=0.569). the histological analysis showed similar patterns of infiltration by small-undifferentiated cells and necrosis in both groups. however, a mild to moderate granulocytic exsudate was more frequent in the animals whose tumors derived from ficoll-isolated cells. hemorrhage from slight to moderate was only observed in this group. conclusion: a ficoll-hypaque gradient can provide more adequate isolation of walker's tumor and the cell suspension obtained by this technique has lower contamination by other cell types.
Brazilian clinical trial of uniform multidrug therapy for leprosy patients: the correlation between clinical disease types and adverse effects
Gon?alves, Heitor de Sá;Pontes, Maria Araci de Andrade;Bührer-Sékula, Samira;Cruz, Rossilene;Almeida, Paulo Cesar;Moraes, Maria Elisabete Amaral de;Penna, Gerson Oliveira;
Memórias do Instituto Oswaldo Cruz , 2012, DOI: 10.1590/S0074-02762012000900013
Abstract: this study sought to verify the correlation between leprosy types and the adverse effects of treatment drugs. this quantitative, prospective, nested study was developed at the dona libania dermatology centre in fortaleza, brazil. data were collected from november 2007-november 2008. during this period, 818 leprosy patients were diagnosed and began treatment. forty patients with tuberculoid leprosy (tt) were selected. twenty patients followed a standard therapy of dapsone and rifampicin and 20 were administered dapsone, rifampicin and clofazimine (u-mdt). twenty patients with borderline lepromatous (bl) and lepromatous leprosy (ll) were also selected and treated with u-mdt. all of the subjects received six doses. with the exception of haemolytic anaemia, there was a low incidence of adverse effects in all the groups. we did not observe any differences in the incidence of haemolytic anaemia or other side effects across groups of patients with tt, bl or ll treated with u-mdt.
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