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Search Results: 1 - 10 of 10572 matches for " Marcos Manzanares "
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Productivity in Physical and Chemical Science Predicts the Future Economic Growth of Developing Countries Better than Other Popular Indices
Klaus Jaffe, Mario Caicedo, Marcos Manzanares, Mario Gil, Alfredo Rios, Astrid Florez, Claudia Montoreano, Vicente Davila
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0066239
Abstract: Scientific productivity of middle income countries correlates stronger with present and future wealth than indices reflecting its financial, social, economic or technological sophistication. We identify the contribution of the relative productivity of different scientific disciplines in predicting the future economic growth of a nation. Results show that rich and poor countries differ in the relative proportion of their scientific output in the different disciplines: countries with higher relative productivity in basic sciences such as physics and chemistry had the highest economic growth in the following five years compared to countries with a higher relative productivity in applied sciences such as medicine and pharmacy. Results suggest that the economies of middle income countries that focus their academic efforts in selected areas of applied knowledge grow slower than countries which invest in general basic sciences.
Hiperglucemia de estrés y su control con insulina en el paciente crítico: evidencia actual
Manzanares,W.; Aramendi,I.;
Medicina Intensiva , 2010,
Abstract: objective: to analyze the current evidence on glycemic control with insulin therapy in the critically ill. recent findings: stress hyperglycemia in critically ill patients has been associated with increased morbidity and mortality. furthermore, current evidence suggests that glucose variability has a predictive value for hospital mortality. initially, the leuven studies showed that intensive insulin therapy was capable of reducing the mortality among surgical and medical icu patients. nevertheless, this strategy significantly increases the incidence of severe hypoglycemia. three important trials on glucose control have been published recently: the visep, the glucontrol study and the nice-sugar. they have shown that strict control of glycemia is associated with a higher incidence of mortality and severe hypoglycemia. furthermore, according to a recent meta-analysis, intensive insulin therapy may be beneficial for patients admitted to a surgical icu. further studies should be able to address some queries about these results on glycemic control in the critically ill.
Selenio en los pacientes críticos con Respuesta Inflamatoria Sistémica
Manzanares Castro,W.;
Nutrición Hospitalaria , 2007,
Abstract: selenium is an essential micronutrient for humans. critically ill patients with systemic inflammatory response syndrome (sirs) and multiple organ dysfunction (mod) -such as severe sepsis, trauma, severe pancreatitis and critical burns- are exposed to severe oxidative stress. these patients exhibit decreased serum selenium and selenoenzymes like glutathione peroxidase and selenoprotein p. selenoenzymes play a major role in protecting cells against lipid peroxidation and they are involved in the inflammatory response regulation. the degree of selenium deficiency correlates with disease severity and the incidence of mortality. in the past years, some clinical trials have studied selenium supplementation effects in critical illness with sirs-mod. this therapeutic strategy could improve the outcome and prognosis in critically ill patients. few small trials have demonstrated selenium supplementation beneficial effects, reducing the rate of infectious complications and length of hospital stay. however, no clinical trials using selenium supplementation in high doses have yet demonstrated significant improvement in mortality. the aims of this review are to evaluate: a) selenium metabolism, b) the role of selenoenzymes during critical illness, c) clinical studies using selenium alone or in combination with other antioxidants in critically ill patients and d) to analyze current parenteral selenium replacement strategies and their results. further multicentre, well designed randomized, double blind clinical trials about selenium supplementation in critically ill patients with sirs and mods are required and appear to be attractive, necessary and challenging.
Suplementación con selenio en el paciente crítico: aspectos farmacológicos y evidencia actual
Manzanares,W.; Hardy,G.;
Nutrición Hospitalaria , 2009,
Abstract: high dose intravenous selenium may be associated with a significant reduction in mortality among critically ill patients with systemic inflammation. currently, parenteral selenium as sodium selenite seems to be a cornerstone of the antioxidant defence in the critically ill. so far, several clinical trials have evaluated the effects of selenium in monotherapy or as part of a multi-micronutrient approach, on relevant clinical end points for critically ill patients. nonetheless, the results from these studies have sometimes been contradictory. we now have a better understanding of the pharmacokinetics of the initial and transient pro-oxidant effect of an intravenous bolus followed by the antioxidant effect of continuous infusion, which seems efficacious and safe among critically ill patients. clinical confirmation of the potentially advantageous synergism between selenium and glutamine may soon be forthcoming but the most appropriate and the optimum time of supplementation remains undetermined. short-term intravenous selenite (bolus injection plus continuous infusion) has shown to be safe and capable of optimizing serum selenium and antioxidant selenoenzymes activities. however, additional dose-ranging trials are necessary to elucidate an optimal and safe posology with confirmed pharmacokinetic profiles before more definitive phase iii trials can be conducted.
Analytic Expression for the Effective Plasma Frequency in One-Dimensional Metallic-Dielectric Photonic Crystal
Jesus Manzanares-Martinez
PIER M , 2010, DOI: 10.2528/PIERM10061905
Abstract: In this work, an analytic expression to define the effective plasma frequency of an one-dimensional periodic system containing alternating dielectric and metallic slabs is proposed. Such metallic elements are considered to have a Drude dielectric function. The effective plasma frequency is obtained as a simple average of the constitutive materials, and its cutoff frequency for the propagating modes is compared with band structure calculations. We also explore the role of absorption in the transparency frequency cutoff.
Hiperglucemia de estrés y su control con insulina en el paciente crítico: evidencia actual Stress hyperglycemia and its control with insulin in critically ill patients: Current evidence
W. Manzanares,I. Aramendi
Medicina Intensiva , 2010,
Abstract: Objetivo: Analizar la evidencia actual sobre el control de la glucemia con insulina en el paciente crítico. La hiperglucemia de estrés incrementa la morbimortalidad en el paciente crítico y se ha reconocido a la variabilidad de la glucemia como un predictor independiente de mortalidad. Inicialmente, los estudios Leuven han demostrado que el control estricto de la glucemia es capaz de reducir la mortalidad en pacientes críticos médicos y quirúrgicos. Sin embargo, esta estrategia terapéutica incrementa de modo significativo la incidencia de hipoglucemia grave. Recientemente, se han publicado los estudios Efficacy of Volume Substitution and Insulin Therapy in Severe Sepsis, GluControl y Normoglycemia in Intensive Care Evaluation and Survival Using Glucose Algorithm Regulation, los que han demostrado que el control estricto de la glucemia incrementa la mortalidad y la incidencia de hipoglucemia grave. Asimismo, un reciente metaanálisis indica que el control estricto de la glucemia podría ser beneficioso en pacientes críticos quirúrgicos. Futuras investigaciones deberían ser capaces de responder algunos interrogantes importantes surgidos a partir de los diferentes estudios existentes. Objective: To analyze the current evidence on glycemic control with insulin therapy in the critically ill. Recent findings: Stress hyperglycemia in critically ill patients has been associated with increased morbidity and mortality. Furthermore, current evidence suggests that glucose variability has a predictive value for hospital mortality. Initially, the Leuven studies showed that intensive insulin therapy was capable of reducing the mortality among surgical and medical ICU patients. Nevertheless, this strategy significantly increases the incidence of severe hypoglycemia. Three important trials on glucose control have been published recently: the VISEP, the Glucontrol study and the NICE-SUGAR. They have shown that strict control of glycemia is associated with a higher incidence of mortality and severe hypoglycemia. Furthermore, according to a recent meta-analysis, intensive insulin therapy may be beneficial for patients admitted to a surgical ICU. Further studies should be able to address some queries about these results on glycemic control in the critically ill.
Encefalopatía hiponatrémica y muerte cerebral en la intoxicación por éxtasis (3,4-metilendioximetanfetamina) Hyponatremic encephalopathy and brain death in Ecstasy (3,4-methylenedioxymethamphetamine) intoxication
I. Aramendi,W. Manzanares
Medicina Intensiva , 2010,
Abstract:
Transferencia de carga a través de la interfase de dos soluciones electrolíticas inmiscibles: fundamento y caso de estudio
Miguel Velázquez Manzanares
Revista de la Sociedad Química de México , 2003,
Abstract: En el presente trabajo se discute la transferencia de carga a través de dos soluciones electrolíticas inmiscibles (sistemas IDSEI). Inicialmente, se exponen los antecedentes y el fundamento de la extracción líquido-líquido mediante técnicas electroquímicas. Posteriormente, se discute la transferencia del catión orgánico tetrametilamonio (TMA+) a través de la interfase agua-1,2-dicloroetano, con el fin de caracterizar las celdas electroquímicas utilizadas en este tipo de sistemas. Finalmente y como caso de estudio, se analiza la transferencia del H+facilitada por la amina 4-octilanilina a través de la interfase agua-1,2-dicloroetano. De esta manera, se muestra que el uso de la IDSEI puede ser una valiosa herramienta para explicar los mecanismos de transferencia de carga en sistemas hidrofóbicos.
La independencia e imparcialidad de los árbitros en el arbitraje comercial internacional desde una perspectiva teórica y práctica.
Bruno Manzanares Bastidas
Revista e-Mercatoria , 2007,
Abstract: El objetivo de este artículo es analizar el papel que juegan los árbitros hoy día dentro del arbitraje comercial internacional y, más concretamente, establecer si los requisitos de imparcialidad e independencia que son obligatorios en cualquier actuación de un juez son aplicables de la misma manera a los árbitros, en especial a aquellos nombrados por las partes.
"Donde quiera que me paro, soy yo". Mujeres indígenas desde una perspectiva de género
Alberti Manzanares, Pilar
Anuario de Estudios Americanos , 1994,
Abstract: Not available. En este artículo se presentan tres puntos de vista acerca de las mujeres indígenas: el académico, el de las instancias oficiales mexicanas y el de las propias mujeres indígenas. El análisis y la crítica que se plantean derivan del marco teórico de la Antropología de Género. De estos tres discursos enfatizo el referido a las propuestas de las mujeres indígenas planteando que existen dos claras vertientes en el mismo: la de la unidad global y la de la conciencia de género. También se mencionan los temas más tratados en el ámbito académico mexicano sobre las mujeres indígenas con la intención de buscar nuevos temas que completen la visión que sobre las mujeres indígenas se tiene actualmente.
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