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Search Results: 1 - 10 of 15370 matches for " Marco Guida "
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Presence of Illicit Drugs in the Sarno River (Campania Region, Italy)  [PDF]
Massimo Maddaloni, Sara Castiglioni, Ettore Zuccato, Flaminia Gay, Anna Capaldo, Vincenza Laforgia, Salvatore Valiante, Maria De Falco, Marco Guida
Pharmacology & Pharmacy (PP) , 2014, DOI: 10.4236/pp.2014.57085
Abstract:

The presence of illicit drugs and their metabolites in surface waters has to be considered a new type of hazard, still unknown, for both the human health and the aquatic ecosystem, due to the potent pharmacological activities of all the illicit drugs. Our research was aimed at evaluating the presence of illicit drugs in the Sarno River (Campania region, Italy), crossing a densely populated area, the basin of the Sarno River, one of the largest and most important economic areas in Campania region, famous for the presence of zones with high landscape-environmental value. The drugs selected for this study were the most used in Campania region. The presence of illicit drugs in surface water was analyzed by a selective multi-residue assay based on liquid chromatographytandem mass spectrometry. The analysis showed the presence of all the illicit drugs investigated: cocaine and its main metabolites (benzoylecgonine, nor-benzoylecgonine), morphine, THC-COOH and codeine; cocaine was the most abundant illicit drug. The presence of illicit drugs and their metabolites in the Sarno River suggests new potential risk for the basin’s inhabitants, using water in the food chain, via field irrigation and animal feed, and for the health of the aquatic fauna.

Assessment of DNA Damage by RAPD in Paracentrotus lividus Embryos Exposed to Amniotic Fluid from Residents Living Close to Waste Landfill Sites
Maurizio Guida,Marco Guida,Bruna De Felice,Daniela Santafede,Raffaella D'Alessandro,Attilio Di Spiezio Sardo,Marianna Scognamiglio,Cinzia Ferrara,Giuseppe Bifulco,Carmine Nappi
Journal of Biomedicine and Biotechnology , 2010, DOI: 10.1155/2010/251767
Abstract: The aim of this study was to assess the genotoxic effects of environmental chemicals on residents living near landfills. The study was based on samples of amniotic fluid from women living in the intensely polluted areas around the Campania region of Italy compared to a nonexposed control group. We evaluated the genetic effects that this amniotic fluids collected in contaminated sites had on Paracentrotus lividus embryos. DNA damage was detected through changes in RAPD (Random Amplified Polymorphism DNA) profiles. The absence of the amplified DNA fragments indicated deletions in Paracentrotus lividus DNA exposed to the contaminated amniotic fluids when compared to equal exposure to uncontaminated fluids. These results show the ability of RAPD-PCR to detect and isolate DNA sequences representing genetic alterations induced in P. lividus embryos. Using this method, we identified two candidate target regions for DNA alterations in the genome of P. lividus. Our research indicates that RAPD-PCR in P. lividus embryo DNA can provide a molecular approach for studying DNA damage from pollutants that can impact human health. To our knowledge, this is the first time that assessment of DNA damage in P. lividus embryos has been tested using the RAPD strategy after exposure to amniotic fluid from residents near waste landfill sites.
Numerical Studies of Disordered Photonic Crystals
G. Guida
PIER , 2003, DOI: 10.2528/PIER02010805
Abstract: Since the first demonstration of a complete photonic band gap by E. Yablonovitch in 1987 [1], photonic band gap materials have attracted a very significant interest in Electromagnetism but also in Solid State Physics. Doped photonic crystals that have a point defect (a local disturbance) have been extensively studied with the emergence of this new area of Physics. They present localized modes in the band gap and triggered many potential applications. Fewer papers have been devoted to strongly disordered photonic crystals that are periodic on the average. These structures are disturbed on the overall feature and the defect corresponding is referred to as extended. Analogue at a first glance to amorphous semiconductors, these materials could present interesting properties. Moreover, manufacture of photonic crystals is still a real challenge for the optical domain and undesirable extended defects can appear leading to a compulsory study of the tolerances of periodicity for such new materials.
L’Invention du Brésil entre deux monarchies. Gouvernement et pratiques politiques de l’Amérique portugaise dans l’union ibérique (1580 - 1640)
Guida Marques
Atelier du Centre de Recherches Historiques , 2010, DOI: 10.4000/acrh.2275
Abstract: Date de soutenance : 20 mai 2009.Composition du JuryMonsieur Pedro Cardim (professeur à l’Université Nouvelle de Lisbonne), Monsieur Guy Saupin (Professeur à l’Université de Nantes), Monsieur Jean - Frédéric Schaub (directeur d’études à l’éHESS), Monsieur Alain Tallon (professeur à l’Université de Paris IV Sorbonne), Monsieur Bernard Vincent (directeur d’études à l’éHESS et directeur de la thèse).RésuméCette thèse explore la dimension impériale de l’union dynastique des couronnes de Portugal ...
Awareness of health risks related to body art practices among youth in Naples, Italy: a descriptive convenience sample study
Francesca Gallè, Caterina Mancusi, Valeria Di Onofrio, Aniello Visciano, Vincenza Alfano, Roberto Mastronuzzi, Marco Guida, Giorgio Liguori
BMC Public Health , 2011, DOI: 10.1186/1471-2458-11-625
Abstract: We investigated perceptions of and knowledge about health risks. To highlight differences among age groups, we gathered data from students at high schools and universities in the province of Naples.Of 9,322 adolescents, 31.3% were pierced and 11.3% were tattooed. Of 3,610 undergraduates, 33% were pierced and 24.5% were tattooed (p < 0.05). A higher number of females were pierced in both samples, but there were no gender differences among tattooed students. Among high school students, 79.4% knew about infectious risks and 46% about non-infectious risks; the respective numbers among university students were 87.2% and 59.1%. Only 3.5% of students in high school and 15% of university undergraduates acknowledged the risk of viral disease transmission; 2% and 3% knew about allergic risks. Among adolescents and young adults, 6.9% and 15.3%, respectively, provided signed informed consent; the former were less knowledgeable about health risks (24.7% vs. 57.1%) (p < 0.05). Seventy-three percent of the high school students and 33.5% of the university students had body art done at unauthorized facilities. Approximately 7% of both samples reported complications from their purchased body art.Results indicate a need for adequate information on health risks associated with body art among students in Naples, mainly among high school students. Therefore, adolescents should be targeted for public health education programs.Recently, piercing and tattooing have gained increasing popularity worldwide. Although the literature differs on the basis of area and population studied, it indicates that body art is increasingly accepted by all social classes and age groups, but especially by youths [1-3]. In Western society, body piercing and tattooing have become mainstream activities among adolescents (12 to 18 years of age) and young adults (18 to 25 years of age) [1,3,4]. Prevalence of body art in these age groups vary by country and setting, ranging from 6.5% to 56% for pierced subjects, and
Antenatal physical activity: Investigating the effects on postpartum depression  [PDF]
Jennifer Guida, Swathy Sundaram, Jenn Leiferman
Health (Health) , 2012, DOI: 10.4236/health.2012.412188
Abstract: Engaging in regular moderate-intensity physical activity has been demonstrated as a successful treatment modality for both major and minor depression and as effective as pharmacologic treatments. However, less is known about the use of antenatal physical activity as a preventive modality for depression during the perinatal period. The objective of the present study was to determine if there is an association between antenatal physical activity and PPD. A cross-sectional study using the 2007-2008 Pregnancy Risk Assessment Monitoring System (PRAMS) data from Colorado and North Carolina (N = 6026) was conducted. PRAMS self-reported data are from a large randomized sample collected by the CDC that assesses maternal demographic, socio-economic, and prepregnancy and perinatal behaviors. Multivariable logistic regression was used to examine the relationship between antenatal sedentary behavior and PPD. Upon adjusting for maternal age, education, race, marital status, parity, stress, smoking, drinking, and prenatal care utilization, women who did not engage in antenatal physical activity were 1.34 times more likely to screen positive for PPD than women who exercised 5 or more days per week [OR 1.34; 95% CI: (1.04, 1.74); p = 0.03]. These findings suggest that not engaging in antenatal exercise may be associated with an increase risk of PPD. Further research is warranted to better understand the effects of antenatal sedentary behavior on PPD and the potential use of physical activity as a preventive modality for PPD.
Increased carotid IMT in overweight and obese women affected by Hashimoto's thyroiditis: an adiposity and autoimmune linkage?
Marco M Ciccone, Giovanni De Pergola, Maria T Porcelli, Pietro Scicchitano, Pasquale Caldarola, Massimo Iacoviello, Guida Pietro, Francesco Giorgino, Stefano Favale
BMC Cardiovascular Disorders , 2010, DOI: 10.1186/1471-2261-10-22
Abstract: A total of 104 obese women (BMI ≥ 25.0 kg/m-2), with FT3 and FT4 serum levels in the normal range and TSH levels < 4.5 μU/ml, were investigated. None of these patients was taking any kind of drug influencing thyroid function. Measurements were made of the IMT-CCT, BMI, waist circumference, blood pressure levels, as well as fasting TSH, FT3, FT4, anti-thyroid antibodies, insulin, fasting glycemia, triglycerides, total and HDL-cholesterol serum concentrations.Of the 104 women, 30 (28.8%) were affected by autoimmune thyroiditis. Significantly higher values of IMT-CCT (p < 0.05), TSH (p < 0.05), and triglycerides (p < 0.05) were obtained, and significantly lower values of FT4 (p < 0.05), in patients with Hashimoto's thyroiditis as compared to those with a normal thyroid function. When examining the whole group together, at multiple regression analysis Hashimoto's thyroiditis maintained a positive association with the IMT (p < 0.001), independently of age, hypertension, BMI, and the fasting serum levels of TSH, FT3, FT4, insulin, fasting glycemia, triglycerides, total and HDL-cholesterol levels.The present study shows that Hashimoto's thyroiditis is associated to an increased IMT only in overweight and obese, independently of the thyroid function, BMI and cardiovascular risk factors. These results suggest that Hashimoto's thyroiditis is a marker of evolution of the atherosclerosis if combined to adiposity.Although published data [1-3] clearly indicate that there is a close relationship between even sub-clinical thyroid dysfunction and an increased cardiovascular risk, the underlying pathogenic process is still unknown. Researchers have so far concentrated on demonstrating the existence of the correlation and evaluating the extent to which different degrees of thyroid dysfunction increase the risk [4-6], but the study populations have rarely been subdivided on the basis of the type of thyroid disease. We believe that this second approach could highlight the close relation
A civiliza??o maia: contextualiza??o historiográfica e arqueológica
Navarro, Alexandre Guida;
História (S?o Paulo) , 2008, DOI: 10.1590/S0101-90742008000100015
Abstract: this article deals with the historiographic and archeological contextualization of the mayan civilization. its purpose is to trace the profile of the first explorations into archeological sites, the construction of the knowledge created around the first information obtained by archeology, as well as the diverse research links undertaken in relation to the historical contexts of its time, and the theories used at present by the mayanists.
Invas?o tolteca em Chichén Itzá? Uma nova leitura da quest?o a partir da cultura material das Terras Maias Baixas do Norte
Navarro, Alexandre Guida;
História (S?o Paulo) , 2010, DOI: 10.1590/S0101-90742010000200016
Abstract: this article aims to study one the most controversial questions about mexican archaeology: the toltec invasion on chichén itzá's city. the issue divides the opinion. there is a group of searches that believe that chichén itzá is a city built by toltecs. on the other hands, others searches thinks that chichén itzá is a city purely maya. in this text, we present some archaeological evidences that show the impossibility of the invasion of tula on chichén itzá's urban centre.
Incidentes críticos na Polícia Judiciária
Manuel,Guida; Soeiro,Cristina;
Análise Psicológica , 2010,
Abstract: the aim of this research is to identify and characterise the main critical incidents experienced by the portuguese criminal investigation police officers and the related stress reactions, to organise a critical incidents intervention program to support those police officers. the data was collected using the critical incidents questionnaire for criminal investigation police (manuel & soeiro, 2009) through 255 individual interviews. the participants described two critical incidents involving operational work, firearms, difficult/violent individuals, evident human suffering and car accidents. participants identify as symptoms, cognitive, emotional and physical reactions. changes in the organisational policy, psychological intervention and increase social support were suggested to avoid critical incidents impact.
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